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  • 1
    Online Resource
    Online Resource
    The endocrine response to acute illness (1999)
    Basel : Karger
    Details Availability
    Keywords: Homeostasis ; Hormones Metabolism ; Endocrine glands Pathophysiology ; Endocrine manifestations of general diseases ; Endocrine Glands metabolism ; Hormones metabolism ; Acute Disease ; Endocrinology ; Biochemistry ; Biology for Physicians ; Genetics ; Molecular Biology ; Neuroendocrinology
    Description / Table of Contents: Advances in medicine have led to the survival of critically ill patients who would previously have died. The physiological response of patients to critical illness is becoming more clearly defined and this book aims to describe the current state of knowledge of the endocrine aspects of that response. The opening chapter with a careful consideration of carbohydrate metabolism, discusses the changes seen in peripheral glucose uptake and hepatic glucose output in illness. In the next chapter body fluids, solutes, osmolality, the role of the kidneys, thirst and its regulation are considered. Chapter three details work which suggests that there is hypersecretion of parathyroid hormone from an early stage of illness, amongst other topics. Characteristic changes seen in thyroid hormone concentrations during illness and the underlying pathophysiological processes are mentioned in chapter four. With further chapters on the Pituitary Gonadal Axis, The Neuroendocrine Regulation of GH Secretion and GH/IGF-1 as Anabolic Therapy this book provides an overview of the current state of knowledge of endocrine and metabolic function in acute illness. This book will be of interest to physicians, anaesthetists and endocrinologists involved in the care of patients with critical illness
    Type of Medium: Online Resource
    Pages: VIII + 206 S
    Edition: Online-Ausg. Online-Ressource Karger eBooks Collection 1997-2009
    ISBN: 9783318003932 , 0585440972 , 9780585440972
    Series Statement: Frontiers of hormone research 24
    URL: http://dx.doi.org/10.1159/isbn.978-3-318-00393-2
    URL: https://karger.com/books/book/2316
    URL: http://www.gbv.de/dms/bowker/toc/9783805568227.pdf
    DOI: 10.1159/isbn.978-3-318-00393-2
    DDC: 616.4
    Language: English
    Note: Includes bibliographical references and index , ""Contents""; ""Preface""; ""Introduction""; ""Glucose Metabolism""; ""Salt and Water Homeostasis""; ""Calcium Metabolism""; ""Thyroid Hormones""; ""The Pituitary Adrenal Axis""; ""The Pituitary Gonadal Axis""; ""The Regulation of Growth Hormone Secretion""; ""Growth Hormone and IGF-I as Anabolic Therapy""; ""Subject Index""; ""A""; ""B""; ""C""; ""D""; ""E""; ""F""; ""G""; ""H""; ""I""; ""L""; ""M""; ""O""; ""P""; ""R""; ""S""; ""T""; ""U""; ""V""
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  • 2
    Electronic Resource
    Electronic Resource
    New source performance standards (1972)
    s.l. : American Chemical Society
    Environmental science & technology 6 (1972), S. 884-888 
    Details
    ISSN: 1520-5851
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology , Energy, Environment Protection, Nuclear Power Engineering
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/es60069a013
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    An origin for arsenobetaine involving bacterial formation of an arsenic–carbon bond (2004)
    Oxford, UK : Blackwell Publishing Ltd
    FEMS microbiology letters 235 (2004), S. 0 
    Details
    ISSN: 1574-6968
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology
    Notes: Lysed-cell extract of a Pseudomonas sp. was shown to catalyse bioconversion of dimethylarsinoylacetate to arsenobetaine and dimethylarsinate. Provision of the universal methyl donor S-adenosylmethionine to bioconversion mixtures promoted both the rate and extent of arsenobetaine formation. These findings suggest that in the proposed biosynthesis of arsenobetaine from dimethylarsinoylethanol, oxidation (i.e. the formation of the carboxymethyl group of dimethylarsinoylacetate) would precede the reduction and methylation at the arsenic atom. The presence of enzyme(s) capable of methylating dimethylarsinoylacetate in a bacterial isolate from marine mussel (Mylitus edulis), highlights a possible direct involvement of prokaryotic organisms in the biosynthesis of organoarsenic compounds within marine animals.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1574-6968.2004.tb09572.x
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  • 4
    Electronic Resource
    Electronic Resource
    New 1:1 adduct of trimethylamine and trichlorosilane, trimethylammonium trichlorosilyl (1971)
    s.l. : American Chemical Society
    Journal of the American Chemical Society 93 (1971), S. 265-267 
    Details
    ISSN: 1520-5126
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/ja00730a053
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  • 5
    Electronic Resource
    Electronic Resource
    Cot mattresses as reservoirs of potentially harmful bacteria and the sudden infant death syndrome (2004)
    Oxford, UK : Blackwell Publishing Ltd
    FEMS immunology and medical microbiology 42 (2004), S. 0 
    Details
    ISSN: 1574-695X
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology , Medicine
    Notes: Cot mattress materials were investigated as potential reservoirs of bacteria in relation to the sudden infant death syndrome (SIDS). The sleeping position of the infant significantly influenced bacterial population density of cot mattress polyurethane foams (p〈0.0000001) and their covers (p〈0.004). Staphylococcus aureus was isolated at significantly higher frequency (p〈0.03) from the infant's head region of cot mattress materials. Significantly higher bacterial population densities (p〈0.001) were associated with polyurethane foams from non-integral mattresses (exposed polyurethane foam), when compared to those from mattresses completely covered by polyvinyl chloride (integral type mattress). The frequency of isolation of S. aureus from polyurethane foams from non-integral mattresses was also significantly higher (p=0.03) than from foams from the integral type. The following factors were significantly associated with increased frequency of isolation of S. aureus: from the polyurethane foam, previous use of non-integral mattresses by another child (p=0.03 for all sample sites, p=0.01 for torso region); from the covers, sleeping in the prone position (p=0.003 head region, p=0.001 torso region). Prone sleeping was also significantly associated with increased bacterial population levels (p=0.01) and increased frequency of isolation of Escherichia coli (p=0.02) from the torso region of cot mattress covers. These findings could explain some recently identified risk factors for SIDS associated with type and previous use of cot mattresses. Clostridium perfringens was isolated at very low frequency and Streptococcus pyogenes was not isolated from any cot mattress materials tested.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1016/j.femsim.2004.06.011
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  • 6
    Electronic Resource
    Electronic Resource
    Evidence for more than one form of toluene cis-glycol dehydrogenase from Pseudomonas putida NCIB11767 (1987)
    Oxford, UK : Blackwell Publishing Ltd
    FEMS microbiology letters 44 (1987), S. 0 
    Details
    ISSN: 1574-6968
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology
    Notes: A number of mutants which were unable to grow on toluene were isolated after transposon mutagenesis of Pseudomonas putida NCIB11767. All of these mutants lacked functional toluene dioxygenase and our inability to isolate other classes of mutant suggested the possible functional or structural duplication of other genes involved in toluene oxidation. However, a mutant lacking toluene cis-glycol (TCG) dehydrogenase (strain NG1) had previously been isolated by NTG mutagenesis. This strain was apparently a double mutant since it reverted to produce two classes of revertant characterised by strains NGL and NGS. Both revertants displayed phenotypic differences from the wild-type strain and further reversion of strain NGS to wild-type was demonstrated. Two protein bands (A and B) possessing TCG-dependent dehydrogenase activity were demonstrated after non-denaturing gel electrophoresis of extracts of strain 11767. Extracts of NGL and NGS displayed only the A or B band, respectively. The TCG dehydrogenase activities of crude extracts of NGL and NGS differed in their sensitivities to inhibitors, substrate affinities and pH optima. We suggest that strain 11767 contains two forms of TCG dehydrogenase which were the products of two different genes.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1574-6968.1987.tb02269.x
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  • 7
    Electronic Resource
    Electronic Resource
    The use of indole as a spectrophotometric assay substrate for toluene dioxygenase (1985)
    Oxford, UK : Blackwell Publishing Ltd
    FEMS microbiology letters 30 (1985), S. 0 
    Details
    ISSN: 1574-6968
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology
    Notes: Abstract Cell extracts of toluene-grown Pseudomonas putida produced a soluble yellow dye during aerobic incubations with indole and NADH. Accumulation of indoxyl in reaction mixtures corresponded with a linear increase in absorbance at 400 nm. The rate of increase in absorbance was shown to be a specific measure of toluene dioxygenase activity. The primary product of toluene oxidation, cis-toluene dihydrodiol, inhibited dioxygenase activity in cell extracts containing no detectable activity of cis-toluene dihydrodiol dehydrogenase.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1574-6968.1985.tb01017.x
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  • 8
    Electronic Resource
    Electronic Resource
    Stressors, burnout and social support: nurses in acute mental health settings (2004)
    Oxford, UK : Blackwell Science Ltd
    Journal of advanced nursing 48 (2004), S. 0 
    Details
    ISSN: 1365-2648
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Aims.  This paper reports a study which aims (1) to investigate and compare levels of stressors and burnout of qualified and unqualified nursing staff in acute mental health settings; (2) to examine the relationships between stressors and burnout and (3) to assess the impact of social support on burnout and stressor–burnout relationships.Background.  Several studies have noted that the work of mental health nurses can be highly stressful, but relatively few have focused specifically on staff working in acute inpatient settings. Although many of the pressures faced by this group are similar to those in other nursing specialities, a number of demands relate specifically to mental health settings, including the often intense nature of nurse–patient interaction and dealing with difficult and challenging patient behaviours on a regular basis.Methods.  A convenience sample of 93 nursing staff from 11 acute adult mental health wards completed the Mental Health Professionals Stress Scale, Maslach Burnout Inventory and House and Wells Social Support Scale.Results.  Lack of adequate staffing was the main stressor reported by qualified staff, while dealing with physically threatening, difficult or demanding patients was the most stressful aspect for unqualified staff. Qualified nurses reported significantly higher workload stress than unqualified staff. Approximately half of all nursing staff showed signs of high burnout in terms of emotional exhaustion. A variety of stressors were positively correlated with emotional exhaustion and depersonalization. Higher levels of support from co-workers were related to lower levels of emotional exhaustion. Higher stressor scores were associated with higher levels of depersonalization for staff reporting high levels of social support, but not for those reporting low levels of support (a reverse buffering effect).Conclusions.  Qualified and unqualified nursing staff differed in terms of the prominence given to individual stressors in their work environment. The findings were consistent with the notion of burnout developing in response to job-related stressors. While staff support groups may be useful in alleviating feelings of burnout, the reverse buffering effect suggests that they should be structured in a way that minimizes negative communication and encourages staff to discuss their concerns in a constructive way.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2648.2004.03240.x
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  • 9
    Electronic Resource
    Electronic Resource
    Are enigmatic markings in Adelaidean of Flinders Ranges fossil ice-tracks? (1986)
    [s.l.] : Nature Publishing Group
    Nature 323 (1986), S. 472-472 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] SEVERAL questions may be raised concerning the provenance of markings recently described by Dyson1 as "unequivocal metazoan remains" from the "base" of the "Wilpena Group" in the southern Flinders Ranges, South Australia. Dyson2 indicated that the markings occurred in sandstones ~25 m ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/323472a0
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  • 10
    Electronic Resource
    Electronic Resource
    The determination of benzidine in wastewaters (1975)
    Springer
    Bulletin of environmental contamination and toxicology 13 (1975), S. 436-442 
    Details
    ISSN: 1432-0800
    Source: Springer Online Journal Archives 1860-2000
    Topics: Energy, Environment Protection, Nuclear Power Engineering , Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01721849
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