Note: Organophosphorus Chemistry -- Contents -- Chapter 1 Phosphines and Phosphonium Salts -- 1 Phosphines -- 1.1 Preparation -- 1.1.1 From Halogenophosphines and Organometallic Reagents -- 1.1.2 From Metallated Phosphines -- 1.1.3 By Addition of P-H to Unsaturated Compounds -- 1.1.4 By Reduction -- 1.1.5 Miscellaneous Methods -- 1.2 Reactions -- 1.2.1 Nucleophilic Attack at Carbon -- 1.2.2 Nucleophilic Attack at Halogen -- 1.2.3 Nucleophilic Attack at Other Atoms -- 1.2.4 Miscellaneous Reactions -- 2 Halogenophosphines -- 2.1 Preparation -- 2.2 Reactions -- 3 Phosphonium Salts -- 3.1 Preparation -- 3.2 Reactions -- 4 pπ-Bonded Phosphorus Compounds -- 5 Phospholes and Phosphorins -- References -- Chapter 2 Pentaco-ordinated and Hexaco-ordinated Compounds -- 1 Introduction -- 2 Structure and Bonding -- 3 Phosphoranes that contain a P-H Bond -- 4 Acyclic Phosphoranes -- 5 Four-membered-ring Phosphoranes -- 6 Five- and Six-membered-ring Phosphoranes -- 7 Hexaco-ordinated Phosphorus Compounds -- References -- Chapter 3 Phosphine Oxides and Related Compounds -- 1 Introduction -- 2 Preparation of Acyclic Phosphine Oxides -- 3 Preparation of Cyclic Phosphine Oxides -- 4 Structure and Physical Aspects -- 5 Reactions at Phosphorus -- 6 Reactions of the Side-chain -- 7 Phosphine Oxide Complexes and Extractants -- References -- Chapter 4 Tervalent Phosphorus Acids -- 1 Introduction -- 2 Nucleophilic Reactions -- 2.1 Attack on Saturated Carbon -- 2.2 Attack on Unsaturated Carbon -- 2.3 Attack on Chalcogen or Halogen -- 3 Electrophilic Reactions -- 3.1 Preparation -- 3.2 Mechanistic Studies -- 3.3 Use for Nucleotide Synthesis -- 3.4 Miscellaneous -- 4 Reactions involving Two-co-ordinate Phosphorus -- 5 Miscellaneous Reactions -- References -- Chapter 5 Quinquevalent Phosphorus Acids -- 1 Introduction -- 2 Phosphoric Acids and their Derivatives -- 2.1 Synthesis. , 2.2 Reactions -- 3 Phosphonic and Phosphinic Acids and their Derivatives -- 3.1 Synthesis -- 3.2 Reactions -- 4 Miscellaneous Syntheses -- 5 Miscellaneous Reactions -- 6 Structure -- References -- Chapter 6 Phosphates and Phosphonates of Biochemical Interest -- 1 Introduction -- 2 Coenzymes and Cofactors -- 3 Sugar Phosphates -- 4 Phospholipids -- 5 Phosphonates -- 6 Enzyme Mechanisms -- 7 Phosphoproteins -- 8 Other Compounds of Biochemical Interest -- References -- Chapter 7 Nucleotides and Nucleic Acids -- 1 Introduction -- 2 Mononucleotides -- 2.1 Chemical Synthesis -- 2.2 Cyclic Nucleotides -- 3 Nucleoside Polyphosphates -- 4 Oligo- and Poly-nucleotides -- 4.1 Chemical Synthesis -- 4.2 Enzymatic Synthesis -- 5 Other studies -- 5.1 Affinity Separation -- 5.2 Affinity Labelling -- 5.3 Post-synthetic Modification -- 5.4 Sequencing and Cleavage Studies -- 5.5 Metal Complexes -- 6 Analytical Techniques and Physical Methods -- References -- Chapter 8 Ylides and Related Compounds -- 1 Introduction -- 2 Methylenephosphoranes -- 2.1 Preparation and Structure -- 2.2 Reactions -- 2.2.1 Reactions with Aldehydes -- 2.2.2 Reactions with Ketones -- 2.2.3 Miscellaneous Reactions -- 3 Reactions of Phosphonate Anions -- 4 Selected Applications in Synthesis -- 4.1 Carbohydrates -- 4.2 β-Lactams -- 4.3 Leukotrienes and Related Compounds -- 4.4 Macrolides -- 4.5 Pheromones -- 4.6 Prostaglandins -- 4.7 Steroids and Related Compounds -- 4.8 Miscellaneous Applications -- References -- Chapter 9 Phosphazenes -- 1 Introduction -- 2 Acyclic Phosphazenes -- 3 Cyclophosphazenes -- 4 Cyclophospha(thia)zenes -- 5 Miscellaneous Phosphazene-containing Ring Systems -- 6 Polyphosphazenes -- 7 Molecular Structures of Phosphazenes Determined by X-Ray Diffraction -- References -- Chapter 10 Physical Methods -- 1 Nuclear Magnetic Resonance Spectroscopy -- 1.1 Biological Aspects. , 1.2 Chemical Shifts and Shielding Effects -- 1.2.1 Phosphorus-31 -- δP of n2 compounds -- δP of n3 compounds -- δP of n4 compounds -- δP of n5 compounds -- 1.2.2 Hydrogen-1 and -2 -- 1.2.3 Carbon-13 -- 1.2.4 Nitrogen-15 and Oxygen-17 -- 1.3 Studies of Equilibria, Shift Reagents, and Medium Effects -- 1.4 Inversion -- 1.5 Restricted Rotation and Pseudorotation -- 1.6 Spin-Spin Couplings -- 1 .6.1 J(PM) and J( PP) -- 1.6.2 J(P15 N) -- 1.6.3 J(PC) -- 1.6.4 J(PH) -- 1.7 Relaxation, N.O.E., and N.Q.R. -- 2 Electron Spin Resonance -- 3 Vibrational and Rotational Spectroscopy -- 3.1 Assignments -- 3.2 Bonding and Reactions -- 3.3 Stereochemistry -- 4 Electronic Spectroscopy -- 4.1 Absorption Spectroscopy -- 4.2 Photoelectron Spectroscopy -- 5 Diffraction -- 5.1 X-Ray Diffraction -- 5.1.1 n1 and n2 Compounds -- 5.1.2 n3 Compounds -- 5.1.3 n4 Compounds -- 5.1.4 n5 Compounds -- 5.2 Electron Diffraction -- 6 Dipole Moments and Kerr Effects -- 7 Mass Spectrometry -- 8 Values of pKa and Thermochemical Studies -- 9 Chromatography -- 9.1 Gas‒Liquid Chromatography -- 9.2 Thin-layer Chromatography -- 9.3 High Performance Liquid Chromatography -- 9.4 Column and Ion-exchange Chromatography -- References -- Author Index.

Note: Organophosphorus Chemistry -- Contents -- Chapter 1 Phosphines and Phosphonium Salts -- 1 Phosphines -- Preparation -- From Halogenophosphines and Organometallic Reagents -- From Metallated Phosphines -- By Addition of P-H to Unsaturated Compounds -- By Reduction -- Miscellaneous Methods of Preparation -- Reactions -- Nucleophilic Attack at Carbon -- Nucleophilic Attack at Halogen -- Nucleophilic Attack at Other Atoms -- Miscellaneous Reactions -- 2 Phosphonium Salts -- Preparation -- Reactions -- Alkaline Hydrolysis -- Additions to Unsaturated Phosphonium Salts -- Miscellaneous Reactions -- 3 Phospholes and Phosphorins -- Chapter 2 Quinquecovalent Phosphorus Compounds -- 1 Introduction -- 2 Structure and Bonding -- 3 Phosphoranes containing a P-H Bond -- 4 Acyclic Phosphoranes -- 5 Four-membered-ring Phosphoranes -- 6 Five-membered-ring Phosphoranes -- 7 Hexaco-ordinated Phosphorus Compounds -- Chapter 3 Halogenophosphines and Related Compounds -- 1 Introduction -- 2 Halogenophosphines -- Preparation -- Reactions with Carbonyl Compounds and Related Compounds -- Reactions with Group V Donors -- Reactions with Carbanions, Alkenes, and Aromatic Compounds -- Insertion Reactions of Silylphosphines -- Physical and Structural Aspects -- 3 Halogenophosphoranes -- Structural -- Preparation -- Reactions with Nitrogen Compounds -- Reactions Relevant to Organic Synthesis -- Chapter 4 Phosphine Oxides and Related Compounds -- 1 Introduction -- 2 Preparation of Acyclic Oxides -- 3 Preparation of Cyclic Oxides -- 4 Structural and Physical Aspects -- 5 Reactions at Phosphorus -- 6 Reactions of the Side-Chain -- 7 Phosphine Oxide Donor-Acceptor Complexes, and Extractants -- Chapter 5 Tervalent Phosphorus Acids -- 1 Introduction -- 2 Phosphorous Acid and its Derivatives -- Nucleophilic Reactions -- Attack on Saturated Carbon -- Attack on Unsaturated Carbon. , Attack on Nitrogen -- Attack on Oxygen -- Attack on Halogen -- Electrophilic Reactions -- Cyclic Esters of Phosphorous Acid -- Miscellaneous Reactions -- 3 Phosphonous and Phosphinous Acids and their Derivatives -- Chapter 6 Quinquevalent Phosphorus Acids -- 1 Synthetic Methods -- General -- Phosphoric Acid and its Derivatives -- Phosphonic and Phosphinic Acids and their Derivatives -- 2 Reactions -- General -- Phosphoric Acid and its Derivatives -- Phosphonic and Phosphinic Acids and their Derivatives -- Chapter 7 Phosphates and Phosphonates of Biochemical Interest -- 1 Introduction -- 2 Coenzymes and Cofactors -- 3 Sugar Phosphates -- 4 Phospholipids -- 5 Phosphonates -- 6 Enzyme Mechanisms -- 7 Phosphorylated Proteins -- 8 Other Compounds of Biochemical Interest -- Chapter 8 Cyclophosphamide and its Congeners -- 1 Introduction -- 2 The Rationale for the Synthesis of Cyclophosphamide -- 3 The Current Status of Knowledge of the Metabolism of Cyclophosphamide -- 4 The Synthesis of Analogues of Cyclophosphamide and their Metabolites -- 5 Biological Properties of Newly Synthesized Analogues of Cyclophosphamide -- 6 Concluding Remarks -- Chapter 9 Nucleotides and Nucleic Acids -- 1 Introduction -- 2 Mononucleotides -- Chemical Synthesis -- Cyclic Nucleotides -- Affinity Chromatography -- 3 Nucleoside Polyphosphates -- Chemical Synthesis -- Affinity Labelling -- 4 Oligo- and Poly-nucleotides -- Chemical Synthesis -- Enzymatic Synthesis -- Sequencing -- Other Studies -- 5 Analytical Techniques and Physical Methods -- Chapter 10 Ylides and Related Compounds -- 1 Methylenephosphoranes -- Preparation and Structure -- Reactions -- Aldehydes -- Ketones -- Miscellaneous -- 2 Reactions of Phosphonate Anions -- 3 Selected Applications in Synthesis -- Pheromones -- Prostaglandins -- Carbohydrates -- Carotenoids and Related Compounds -- β-Lactam Antibiotics. , Non-benzenoid Aromatic Compounds -- Miscellaneous Applications -- Chapter 11 Physical Methods -- 1 Nuclear Magnetic Resonance Spectroscopy -- Biological Applications and Instrumental Techniques -- Chemical Shifts and Shielding Effects -- Phosphorus-31 -- δP of n2 compounds -- δP of n3 compounds -- δP of n4 compounds -- δP of n6 compounds -- Carbon-13 -- Nitrogen-15 -- Chlorine-35 -- Studies of Equilibria, Shift Reagents, and Liquid Crystals -- Variable-temperature Studies -- Pseudorotation -- Restricted Rotation -- Studies of Configuration -- Spin-Spin Coupling -- J(PP) and J(PM) -- J(PC) -- J(PH) -- J(PCnH) and J(PXCnH) -- Studies of Relaxation, CIDNP, and N.Q.R. -- 2 Electron Spin Resonance Spectroscopy -- 3 Vibrational and Rotational Spectroscopy -- Band Assignments and Absorptivity -- Bonding -- Stereochemistry -- Rotational Data -- 4 Electronic Spectroscopy -- Absorption Spectroscopy -- Photoelectron Spectroscopy -- X-Ray Fluorescence Spectroscopy -- 5 Diffraction -- X-Ray Diffraction -- Electron Diffraction -- 6 Dipole Moments and the Kerr Effect -- 7 Mass Spectrometry -- 8 pKa and Thermochemical and Kinetic Studies -- 9 Chromatography -- Gas-Liquid Chromatography -- Thin-layer Chromatography and Paper Chromatography -- High-performance Liquid Chromatography -- Column Chromatography -- Author Index.

Note: Organophosphorus Chemistry -- Contents -- Chapter 1 Phosphines and Phosphonium Salts -- 1 Phosphines -- Preparation -- From Halogenophosphines and Organometallic Reagents -- From Metallated Phosphines -- By Addition of P-H to Unsaturated Compounds -- By Reduction -- Miscellaneous -- Reactions -- Nucleophilic Attack at Carbon -- Nucleophilic Attack at Halogen -- Nucleophilic Attack at Other Atoms -- Miscellaneous -- 2 Phosphonium Salts -- Preparation -- Reactions -- Alkaline Hydrolysis -- Additions to Unsaturated Phosphonium Salts -- Miscellaneous -- 3 Phospholes -- 4 Phosphorins -- Chapter 2 Quinquecovalent Phosphorus Compounds -- 1 Introduction -- 2 Structure and Bonding -- 3 Acyclic Systems -- 4 Four-membered Rings -- 5 Five-membered Rings -- Phospholans -- 1,2-Oxaphospholans -- 1,2-Oxaphospholens -- 1,3,2-Dioxaphospholans -- 1,3,2-Dioxaphospholens -- Nitrogen-containing Rings -- 6 Six-membered Rings -- 7 Higher-membered Rings -- 8 Six-co-ordinate Species -- Chapter 3 Halogenophosphines and Related Compounds -- 1 Introduction -- 2 Halogenophosphines -- Preparation -- Reactions with Alkenes and Related Compounds -- Reactions with Carbonyl Compounds and their Derivatives -- Reactions with Hydroxy-groups -- Reactions with Amines and Derivatives -- Miscellaneous Aspects -- Silylphosphines and Related Compounds -- 3 Halogenophosphoranes -- Preparation -- By Addition of Halogen to Phosphorus(III) -- By Insertion of Phosphorus(III) into other Halogen Compounds -- By Reactions of Phosphorus(III) with C=O Compounds -- By Exchange Reactions of Phosphoranes -- From Arsenic(IV) Compounds -- Reactions of Halogenophosphoranes -- Miscellaneous -- Chapter 4 Phosphine Oxides and Sulphides -- 1 Introduction -- 2 Preparation -- via Alkenes -- via Carbonyl Compounds -- via Phosphorus(IV) Chlorides -- P-P Compounds via P(O) Anions -- Miscellaneous Syntheses. , 3 Reactions -- Reactions at the P=X Group -- Reactions of the Side-chain -- 4 Structural and Physical Properties -- Chapter 5 Tervalent Phosphorus Acids -- 1 Phosphorous Acid and its Derivatives -- Nucleophilic Reactions -- Attack on Saturated Carbon -- Attack on Unsaturated Carbon -- Attack on Nitrogen -- Attack on Oxygen -- Attack on Halogen -- Electrophilic Reactions -- Rearrangements -- Cyclic Esters of Phosphorous Acid -- Miscellaneous Reactions -- 2 Phosphonous and Phosphinous Acids and their Derivatives -- Chapter 6 Quinquevalent Phosphorus Acids -- 1 Synthetic Methods -- General -- Phosphoric Acid and its Derivatives -- Phosphonic and Phosphinic Acids and their Derivatives -- 2 Reactions -- General -- Reactions of Phosphoric Acid and its Derivatives -- Reactions of Phosphonic and Phosphinic Acids and their Derivatives -- 3 Structure -- Chapter 7 Phosphates and Phosphonates of Biochemical Interest -- 1 Introduction -- 2 Coenzymes and Cofactors -- Nicotinamide Nucleotides -- Pyridoxal Phosphate -- Other Cofactors -- 3 Sugar Phosphates -- 4 Phospholipids -- 5 Phosphonates -- 6 Oxidative Phosphorylation -- 7 Enzymology -- Enzyme Mechanisms -- Phosphoproteins -- Protein Purification -- 8 Other Compounds of Biochemical Interest -- Chapter 8 Nucleotides and Nucleic Acids -- 1 Introduction -- 2 Mononucleotides -- Chemical Synthesis -- Cyclic Nucleotides -- Affinity Chromatography -- 3 Polyphosphates -- Chemical Synthesis -- Affinity Labelling -- 4 Oligo- and Poly-nucleotides -- Chemical Synthesis -- Enzymatic Synthesis -- Sequencing -- Other Studies -- 5 Analytical Techniques and Physical Methods -- Chapter 9 Ylides and Related Compounds -- 1 Methylenephosphoranes -- Preparation and Structure -- Reactions -- Aldehydes -- Ketones -- Miscellaneous -- 2 Reactions of Phosphonate Anions -- 3 Selected Applications in Synthesis -- Pheromones. , Prostaglandins -- Carbohydrates -- Carotenoids -- Non-benzenoid Aromatic Compounds -- Chapter 10 Phosphazenes -- 1 Introduction -- 2 Synthesis of Acyclic Phosphazenes -- From Amines and Phosphorus(V) Halides -- From Azides and Phosphorus(III) Compounds -- Other Methods -- 3 Properties of Acyclic Phosphazenes -- Halogeno-derivatives -- Amino-, Alkoxy-, Alkyl-, and Aryl-derivatives -- 4 Synthesis of Cyclic Phosphazenes -- 5 Properties of Cyclic Phosphazenes -- Halogeno-derivatives -- Amino-derivatives -- Alkoxy- and Aryloxy-derivatives -- Alkyl and Aryl Derivatives -- 6 Polymeric Phosphazenes -- 7 Phosphazenes as Fire Retardants -- 8 Molecular Structures of Phosphazenes that have been determined by X-Ray Diffraction Methods -- Chapter 11 Physical Methods -- 1 Nuclear Magnetic Resonance Spectroscopy -- Biological Applications -- Chemical Shifts and Shielding Effects -- Phosphorus-31 -- δP of PII Compounds -- δP of PIII Compounds -- δP of PIV Compounds -- δP of PV Compounds -- Carbon-13 -- Fluorine-19 -- Oxygen-17 and Nitrogen-15 and -14 -- Hydrogen-1 -- Equilibria and Shift Reagents -- Pseudorotation -- Restricted Rotation -- Inversion, Configuration, and Medium Effects -- Spin-Spin Coupling -- JPP -- JP17O and JP15N -- JPC -- JPH -- JPCnH -- JPXCH -- Double-resonance, Relaxation, C.I.D.N.P., and N.Q.R. Studies -- 2 Electron Spin Resonance Spectroscopy -- 3 Vibrational and Rotational Spectroscopy -- Band Assignments -- Stereochemistry -- Bonding -- Microwave Spectra -- 4 Electronic Spectroscopy -- Absorption -- Photoelectron -- 5 Diffraction -- X-Ray -- Electron -- 6 Dipole Moments, Conductance, and Polarography -- 7 Mass Spectrometry -- 8 pKa and Thermochemical Studies -- 9 Chromatography -- G.l.c. -- T.l.c. -- Paper Chromatography -- Column Chromatography -- Author Index.

Note: Organophosphorus Chemistry -- Contents -- Chapter 1 Phosphines and Phosphonium Salts -- 1 Phosphines -- 1.1 Preparation -- 1.1.1 From Halogenophosphines and Organometallic Reagents -- 1.1.2 From Metallated Phosphines -- 1.1.3 By Addition of P-H to Unsaturated Compounds -- 1.1.4 By Reduction -- 1.1.5 Miscellaneous Methods -- 1.2 Reactions -- 1.2.1 Nucleophilic Attack at Carbon -- 1.2.2 Nucleophilic Attack at Halogen -- 1.2.3 Nucleophilic Attack at Other Atoms -- 1.2.4 Miscellaneous Reactions -- 2 Halogenophosphines -- 2.1 Preparation -- 2.2 Reactions -- 3 Phosphonium Salts -- 3.1 Preparation -- 3.2 Reactions -- 4 pΠ-Bonded Phosphorus Compounds -- 5 Phospholes and Phosphorins -- References -- Chapter 2 Quinquecovalent Phosphorus Compounds -- 1 Introduction -- 2 Structure, Bonding, and Ligand Reorganization -- 3 Phosphoranes Containing a P-H Bond -- 4 Acyclic Phosphoranes -- 5 Ring-containing Phosphoranes -- 5.1 Monocyclic Phosphoranes -- 5.2 Bicyclic and Tricyclic Phosphoranes -- 6 Hexaco-ordinate Phosphorus Compounds -- References -- Chapter 3 Phosphine Oxides and Related Compounds -- 1 Introduction -- 2 Preparation of Acyclic Phosphine Oxides -- 3 Preparation of Cyclic Phosphine Oxides -- 4 Structure and Physical Aspects -- 5 Reactions at Phosphorus -- 6 Reactions at the Side-chain -- 7 Phosphine Oxide Complexes and Extractants -- References -- Chapter 4 Tervalent Phosphorus Acids -- 1 Introduction -- 2 Nucleophilic Reactions -- 2 . 1 Attack on Saturated Carbon -- 2 . 2 Attack on Unsaturated Carbon -- 2 . 3 Attack on Nitrogen, Chalcogen, or Halogen -- 3 Electrophilic Reactions -- 3.1 Preparation -- 3.2 Mechanistic Studies -- 3.3 Use for Nucleotide Synthesis -- 3.4 Miscellaneous -- 4 Reactions involving Two-co-ordinate Phosphorus -- 5 Miscellaneous Reactions -- References -- Chapter 5 Quinquevalent Phosphorus Acids -- 1 Introduction. , 2 Phosphoric Acids and their Derivatives -- 2.1 Synthesis -- 2.2 Reactions and Properties -- 3 Phosphonic and Phosphinic Acids and their Derivatives -- 3 . 1 Synthesis -- 3 . 2 Reactions -- 4 Miscellaneous Syntheses and Reactions -- References -- Chapter 6 Phosphates and Phosphonates of Biochemical -- 1 Introduction -- 2 Coenzymes and Cofactors -- 3 Sugar Phosphates -- 4 Phospholipids -- 5 Phosphonates -- 6 Enzyme Mechanisms and Phosphoproteins -- 7 Other Compounds of Biochemical Interest -- References -- Chapter 7 Nucleotides and Nucleic Acids -- 1 Introduction -- 2 Mononucleotides -- 2.1 Chemical Synthesis -- 2.2 Cyclic Nucleotides -- 3 Nucleoside Polyphosphates -- 4 Oligo- and Poly-nucleotides -- 4.1 Chemical Synthesis -- 4.2 Enzymatic Synthesis -- 5 Other Studies -- 5.1 Affinity Separation -- 5.2 Affinity Labelling -- 5.3 Post-synthetic Modification -- 5.4 Sequencing and Cleavage Studies -- 5.5 Metal Complexes -- 6 Analytical Techniques and Physical Methods -- References -- Chapter 8 Ylides and Related Compounds -- 1 Introduction -- 2 Methylenephosphoranes -- 2.1 Preparation and Structure -- 2.2 Reactions -- 2. 2.1 Reactions with Aldehydes -- 2.2.2 Reactions with Ketones -- 2.2.3 Miscellaneous Reactions -- 3 Reactions of Phosphonate Anions -- 4 Selected Applications in Synthesis -- 4.1 Carotenoids and Retinoids -- 4.2 β-Lactams -- 4.3 Leukotrienes and Related Compounds -- 4.4 Macrolides -- 4.5 Pheromones -- 4.6 Miscellaneous Applications -- References -- Chapter 9 Phosphazenes -- 1 Introduction -- 2 Acyclic Phosphazenes -- 3 Cyclophosphazenes -- 4 Cyclophospha(thia)zenes -- 5 Miscellaneous Phosphazene-containing Ring Systems -- 6 Polyphosphazenes -- 7 Molecular Structures of Phosphazenes -- References -- Chapter 10 Physical Methods -- 1 Nuclear Magnetic Resonance Spectroscopy -- 1.1 Biological Applications and Instrumental Techniques. , 1.2 Chemical Shifts and Shielding Effects -- 1.2.1 Phosphorus-31 -- δp of n2 compounds -- δp of n3 compounds -- δp of n4 compounds -- δP of n5 compounds -- δp of n6 compounds -- 1.2.2 Hydrogen-1 and -2 -- 1.3 Studies of Shift Reagents, Medium Effects, Liquid Crystals, and Solids -- 1.4 Inversion, Restricted Rotation, and Permutational Isomerism -- 1.5 Spin-Spin Couplings -- 1.5.1 J(PM) and J ( P P ) -- 1.5.2 J(PF) and J(PN) -- 1.5.3 J(PC) -- 1.5.4 J(PH) and J(P0CH) -- 1.6 Relaxation and N.Q.R. -- 2 Electron Spin Resonance -- 3 Vibrational Spectroscopy -- 3.1 Assignments -- 3.2 Bonding -- 3.3 Stereochemistry -- 4 Rotational Spectroscopy -- 5 Electronic Spectroscopy -- 5.1 Absorption Spectroscopy -- 5.2 Fluorescence -- 5.3 Optical Rotation -- 5.4 Photoelectron and X-Ray Spectroscopy -- 5.4.1 Photoelectron Spectroscopy -- 5.4.2 ESCA -- 6 Diffraction -- 6.1 X-R.ay Diffraction -- 6.1.1 n2 Compounds -- 6.1.2 n3 Compounds -- 6.1.3 n4 Compounds -- 6.1.4 n5 and n6 Compounds -- 6.2 Electron Diffraction -- 7 Dipole Moments, Kerr Effects, Polarography, and Conductance -- 7.1 Dipole Moment and Kerr Effect -- 7.2 Polarography and Conductance -- 8 Mass Spectrometry -- 9 Acidities, Basicities, and Thermochemistry -- 10 Chromatography -- 10.1 Gas-Liquid Chromatography -- 10.2 Thin-layer Chromatography -- 10.3 Liquid Chromatography -- 10.4 Gel Chromatography -- 10.5 Osmotic Properties, Solubilities, and Vapour Pressures -- References -- Author Index.

Note: OG9780851869803-FX001 -- OG9780851869803-FP001 -- OG9780851869803-FP005 -- OG9780851869803-FP007 -- OG9780851869803-FP013 -- OG9780851869803-00001 -- OG9780851869803-00033 -- OG9780851869803-00051 -- OG9780851869803-00069 -- OG9780851869803-00083 -- OG9780851869803-00104 -- OG9780851869803-00136 -- OG9780851869803-00150 -- OG9780851869803-00192 -- OG9780851869803-00219 -- OG9780851869803-00247 -- OG9780851869803-00273.

Note: Organophosphorus Chemistry -- Contents -- Chapter 1 Phosphines and Phosphonium Salts -- 1 Phosphines -- Preparation -- From Halogenophosphines and Organometallic Reagents -- From Metallated Phosphines -- By Addition of P-H to Unsaturated Compounds -- By Reduction -- Miscellaneous Methods -- Reactions -- Nucleophilic Attack at Carbon -- Nucleophilic Attack at Halogen -- Nucleophilic Attack at Other Atoms -- Miscellaneous Reactions -- 2 Phosphonium Salts -- Preparation -- Reactions -- Alkaline Hydrolysis -- Additions to Unsaturated Phosphonium Salts -- Miscellaneous Reactions -- 3 pπ-Bonded Phosphorus Compounds -- 4 Phospholes and Phosphorins -- Chapter 2 Quinquecovalent Phosphorus Compounds -- 1 Introduction -- 2 Structure, Bonding, and Reorganization of Ligands -- 3 Phosphoranes that contain a P-H Bond -- 4 Acyclic Phosphoranes -- 5 Four-membered-ring Phosphoranes -- 6 Five-membered-ring Phosphoranes -- 7 Six- and Seven-membered-ring Phosphoranes -- 8 Hexaco-ordinated Phosphorus Compounds -- Chapter 3 Halogenophosphines and Related Compounds -- 1 Introduction -- 2 Halogenophosphines -- Preparation -- Physical and Structural Aspects -- Reactions that lead to pπ Bonds to Phosphorus -- Reactions with Alkenes or Dienes -- Reactions with Carbanions -- Reactions with Carbonyl Compounds -- Reactions with Oxygen Nucleophiles -- Reactions with Phosphorus Nucleophiles -- Miscellaneous Reactions -- 3 Silylphosphines -- 4 Halogenophosphoranes -- Preparation -- Physical and Structural Aspects -- Reactions -- Chapter 4 Phosphine Oxides and Related Compounds -- 1 Introduction -- 2 Preparation of Acyclic Oxides -- 3 Preparation of Cyclic Oxides -- 4 Structural and Physical Aspects -- 5 Reactions at Phosphorus -- 6 Reactions of the Side-Chain -- 7 Phosphine Oxide Complexes and Extractants -- Chapter 5 Tervalent Phosphorus Acids -- 1 Introduction. , 2 Phosphorous Acid and its Derivatives -- Nucleophilic Reactions -- Attack on Saturated Carbon -- Attack on Unsaturated Carbon -- Attack on Oxygen -- Attack on Halogen -- Electrophilic Reactions -- Reactions involving Two- co-ordinate Phosphorus -- Cyclic Esters of Phosphorous Acid -- Miscellaneous Reactions -- 3 Phosphonous and Phosphinous Acids and their Derivatives -- Chapter 6 Quinquevalent Phosphorus Acids -- 1 Synthesis -- General -- Phosphoric Acid and its Derivatives -- Phosphonic and Phosphinic Acids and their Derivatives -- 2 Reactions -- General -- Phosphoric Acid and its Derivatives -- Phosphonic and Phosphinic Acids and their Derivatives -- Chapter 7 Phosphates and Phosphonates of Biochemical Interest -- 1 Introduction -- 2 Coenzymes and Cofactors -- 3 Sugar Phosphates -- 4 Phospholipids -- 5 Phosphonates -- 6 Enzyme Mechanisms -- 7 Other Compounds of Biochemical Interest -- Chapter 8 Nucleotides and Nucleic Acids -- 1 Introduction -- 2 Mononucleotides -- Chemical Synthesis -- Cyclic Nucleotides -- Affinity Chromatography -- 3 Nucleoside Polyphosphates -- Chemical Synthesis -- Affinity Labelling -- 4 Oligo- and Poly-nucleotides -- Chemical Synthesis -- Enzymatic Synthesis -- Sequencing -- Other Studies -- 5 Analytical Techniques and Physical Methods -- Chapter 9 Ylides and Related Compounds -- 1 Introduction -- 2 Methylenephosphoranes -- Preparation and Structure -- Reactions -- Aldehydes -- Ketones -- Miscellaneous -- 3 Reactions of Phosphonate Anions -- 4 Selected Applications in Synthesis -- Carbohydrates -- Carotenoids and Related Compounds -- β-Lactam Antibiotics -- Leucotrienes and Related Compounds -- Pheromones -- Prostaglandins -- Miscellaneous Applications -- Chapter 10 Mass Spectrometry of Organophosphorus Compounds -- 1 Introduction -- 2 Techniques -- Chemical Ionization and 'In-Beam' Evaporation Techniques. , Negative-ion Chemical Ionization -- Field Desorption and lonization by Energetic Particles -- Identification of Metastable Ions -- Liquid Chromatography -- 3 Natural Products -- Nucleotides -- Phospholipids -- Miscellaneous Natural Phosphates -- 4 Synthetic Compounds -- Organophosphorus Ester Pesticides -- Phosphates -- Phosphonates -- Phosphites -- Phosphinates -- Phosphines -- Phosphonium Salts -- Phosphazenes -- Miscellaneous -- Chapter 11 Physical Methods -- 1 Nuclear Magnetic Resonance Spectroscopy -- Biological, Analytical, and Instrumental Aspects -- Chemical Shifts and Shielding Effects -- Phosphorus-31 -- δp of n1 compounds -- δp of n2 compounds -- δp of n3 compounds -- δp of n4 compounds -- δp of n5 compounds -- Hydrogen-1, -2, and -3 -- Carbon-13 -- Oxygen-17 -- Fluorine-19 -- Studies of Equilibria, Hydrogen-Bonding, and Shift Reagents -- Variable-Temperature Studies: Inversion -- Restricted Rotation and Conformation -- Pseudorotation -- Spin-Spin Couplings -- J(PM) and J(PP) -- J(PF) -- J(PN) -- J(PC) -- 1J(PD) -- 2J(PCH) -- J(PCCnH) and J(POCnH) -- Relaxation, CIDNP, and N.Q.R. -- Relaxation -- CIDNP -- N.Q.R. -- 2 Electron Spin Resonance Spectroscopy -- 3 Vibrational and Rotational Spectroscopy -- Band Assignments and Absorptivity -- Bonding -- Stereochemistry -- Rotational Data -- 4 Electronic Spectroscopy -- Absorption Spectroscopy -- Photoelectron Spectroscopy -- Optical Rotation -- 5 Diffraction -- X-Ray Diffraction -- Electron Diffraction -- 6 Dipole Moments and Kerr Effects -- 7 Values of pKa and Thermochemical and Kinetic Studies -- 8 Chromatography and Surface Properties -- Gas-Liquid Chromatography -- Thin-Layer, Paper, and Gel Chromatographies -- High-Performance Liquid Chromatography -- Column Chromatography -- Surface Properties -- Author Index.

Note: Organophosphorus Chemistry -- Contents -- Chapter 1 Phosphines and Phosphonium Salts -- 1 Phosphines -- Preparation -- From Halogenophosphines and Organometallic Reagents -- From Metallated Phosphines -- By Addition of P-H to Unsaturated Compounds -- By Reduction -- Miscellaneous Methods -- Reactions -- Nucleophilic Attack at Carbon -- Nucleophilic Attack at Halogen -- Nucleophilic Attack at Other Atoms -- Miscellaneous -- 2 Phosphonium Salts -- Preparation -- Reactions -- Alkaline Hydrolysis -- Additions to Unsaturated Phosphonium Salts -- Miscellaneous -- 3 Phospholes and Phosphorins -- Chapter 2 Quinquecovalent Phosphorus Compounds -- 1 Introduction -- 2 Structure and Bonding -- 3 Hydroxyphosphoranes -- 4 PH-Phosphoranes -- 5 Acyclic Phosphoranes -- 6 Four-membered Phosphoranes -- 7 Five-membered Phosphoranes -- 8 Six-membered Phosphoranes -- 9 Six-co-ordinate Species -- Chapter 3 Halogenophosphines and Related Compounds -- 1 Introduction -- 2 Halogenophosphines -- Preparation -- Physical and Structural Properties -- Reactions with Alkenes or Alkynes -- Reactions with Amines and Derivatives -- Reactions with Carbonyl Compounds -- Reactions with Acetals and Alcohols -- Reactions with Phosphorus(III) Compounds -- Miscellaneous Reactions -- 3 Silylphosphines -- 4 Halogenophosphoranes -- Preparation -- Physical and Structural Aspects -- Reactions -- Reactions that are Relevant to Organic Synthesis -- Chapter 4 Phosphine Oxides and Related Compounds -- 1 Introduction -- 2 Preparation of Simple Oxides -- 3 Preparations and Reactions Related to Alkene Synthesis -- 4 Reactions and Properties involving the P=O Group -- 5 Reactions of the Side-chain -- 6 Chemistry of Cyclic Phosphine Oxides -- 7 Miscellaneous Structural and Physical Aspects -- Chapter 5 Tervalent Phosphorus Acids -- 1 Phosphorous Acid and its Derivatives -- Nucleophilic Reactions. , Attack on Saturated Carbon -- Attack on Unsaturated Carbon -- Attack on Nitrogen -- Attack on Oxygen -- Attack on Halogen -- Electrophilic Reactions -- Cyclic Esters of Phosphorous Acid -- Miscellaneous Reactions -- 2 Phosphonous and Phosphinous Acids and their Derivatives -- Chapter 6 Quinquevalent Phosphorus Acids -- 1 Synthetic Methods -- General -- Phosphoric Acid and its Derivatives -- Phosphonic and Phosphinic Acids and their Derivatives -- 2 Reactions -- General -- Phosphoric Acid and its Derivatives -- Phosphonic and Phosphinic Acids and their Derivatives -- Chapter 7 Phosphates and Phosphonates of Biochemical Interest -- 1 lntroduction -- 2 Coenzymes and Cofactors -- Nicotinamide Coenzymes -- Phosphoenolpyruvate -- Pyridoxal Phosphate -- Other Coenzymes -- 3 Sugar Derivatives -- 4 Phospholipids -- 5 Phosphonates -- 6 Enzymology -- Enzyme Mechanisms -- Phosphoproteins -- 7 Other Compounds of Biochemical Interest -- Chapter 8 Phosphoryl Transfer from Phosphomonoesters and Adenosine 5′-Triphosphate -- 1 Types of Phosphoryl Transfer -- 2 Phosphoryl Transfer from Aryl Dihydrogen Phosphates -- 3 Does PO3- Add to Non-enolized Ketones in Solution? -- 4 Mechanims of Non-enzymatic Phosphoryl Transfer from ATP -- 5 Enzymatic Hydrolysis of ATP : Actomyosin MgATPase in Muscle Contraction -- Chapter 9 Nucleotides and Nucleic Acids -- 1 Introduction -- 2 Mononucleotides -- Chemical Synthesis -- Cyclic Nucleotides -- Affinity Chromatography -- 3 Nucleoside Polyphosphates -- Chemical Synthesis -- Affinity Labelling -- 4 Oligo- and Poly-nucleotides -- Chemical Synthesis -- Enzymatic Synthesis -- Sequencing -- Other Studies -- 5 Analytical Techniques and Physical Methods -- Chapter 10 Ylides and Related Compounds -- 1 Methylenephosphoranes -- Preparation and Structure -- Reactions -- Aldehydes -- Ketones -- Miscellaneous -- 2 Reactions of Phosphonate Anions. , 3 Selected Applications in Synthesis -- Pheromones -- Prostaglandins -- Carbohydrates -- Carotenoids -- Non-benzenoid Aromatic Compounds -- Miscellaneous -- Chapter 11 Physical Methods -- 1 Nuclear Magnetic Resonance Spectroscopy -- Biological and Analytical Applications -- Chemical Shifts and Shielding Effects -- Phosphorus-31 -- δP of PII compounds -- δp of PIII and PIV compounds -- δp of PV and PVI compounds -- Carbon-13 -- Hydrogen-1 -- Equilibria, Shift Reagents, and Liquids Crystals -- Variable-temperature Studies -- Pseudorotation and Restricted Rotation -- Other Studies -- Configuration -- Spin-Spin Coupling -- JPP and JPM -- JPF and JPN -- JPC -- JPH -- JPCnH -- Relaxation and N.Q.R. Studies -- 2 Electron Spin Resonance Spectroscopy -- 3 Vibrational and Rotational Spectroscopy -- Band Assignments -- Stereochemistry -- Bonding -- Microwave Spectra -- 4 Electronic Spectroscopy -- Absorption -- Photoelectron -- 5 Diffraction -- X-Ray -- Electron and Neutron -- 6 Dipole Moments, Kerr Effect, and Polarography -- Dipole Moments and Kerr Effect -- Polarographic Studies -- 7 Mass Spectrometry -- 8 pKa, Thermochemical, and Kinetic Studies -- 9 Chromatography -- G.l.c. -- T.l.c. -- H.p.l.c. -- Column and Gel Chromatography -- Author Index.

Note: Organophosphorus Chemistry -- Contents -- Chapter 1 Phosphines and Phosphonium Salts -- 1 Phosphines -- Preparation -- From Halogenophosphines and Organometallic Reagents -- From Metallated Phosphines -- By Addition of P-H to Unsaturated Compounds -- By Reduction -- Miscellaneous Methods -- Reactions -- Nucleophilic Attack at Carbon -- Nucleophilic Attack at Halogen -- Nucleophilic Attack at Other Atoms -- Miscellaneous Reactions -- 2 Phosphonium Salts -- Preparation -- Reactions -- 3 pπ-Bonded Phosphorus Compounds -- 4 Phospholes and Phosphorins -- Chapter 2 Quinquecovalent Phosphorus Compounds -- 1 Introduction -- 2 Structure, Bonding, and Reorganization of Ligands -- 3 Phosphoranes containing a P-H Bond -- 4 Acyclic Phosphoranes -- 5 Three-, Four-, and Five-membered-ring Phosphoranes -- Monocyclic Systems -- Bicyclic Systems -- Tricylic Systems -- 6 Six-co-ordinated Phosphorus Compounds -- Addendum -- Chapter 3 Phosphine Oxides and Related Compounds -- 1 Introduction -- 2 Preparation of Acyclic Phosphine Oxides -- 3 Preparation of Cyclic Phosphine Oxides -- 4 Structural and Physical Aspects -- 5 Reactions at Phosphorus -- 6 Reactions of the Side-chain -- 7 Phosphine Oxide Complexes and Extractants -- Chapter 4 Tervalent Phosphorus Acids -- 1 Introduction -- 2 Nucleophilic Reactions -- Attack on Saturated Carbon -- Attack on Unsaturated Carbon -- Attack on Oxygen or Sulphur -- Attack on Halogen -- 3 Electrophilic Reactions -- 4 Reactions involving Two-co-ordinate Phosphorus -- 5 Miscellaneous Reactions -- Chapter 5 Quinquevalent Phosphorus Acids -- 1 Synthetic Methods -- General -- Phosphoric Acids and their Derivatives -- Phosphonic and Phosphinic Acids and their Derivatives -- 2 Reactions -- General -- Phosphoric Acids and their Derivatives -- Phosphonic and Phosphinic Acids and their Derivatives. , Chapter 6 Phosphates and Phosphonates of Biochemical Interest -- 1 Introduction -- 2 Coenzymes and Cofactors -- 3 Sugar Phosphates -- 4 Phospholipids -- 5 Phosphonates -- 6 Enzyme Mechanisms -- 7 Other Compounds of Biochemical Interest -- Chapter 7 Nucleotides and Nucleic Acids -- 1 Introduction -- 2 Mononucleotides -- Chemical Synthesis -- Cyclic Nucleotides -- 3 Nucleoside Polyphosphates -- 4 Oligo- and Poly-nucleotides -- Chemical Synthesis -- Enzymatic Synthesis -- 5 Other Studies -- Affinity Separation -- Affinity Labelling -- Post Synthetic Modification -- Sequencing and Cleavage Studies -- Metal Complexes -- 6 Analytical Techniques and Physical Methods -- Chapter 8 Ylides and Related Compounds -- 1 Introduction -- 2 Methylenephosphoranes -- Preparation and Structure -- Reactions of Methylenephosphoranes - Aldehydes -- Reactions of Ketones with Methylenephosphoranes -- Miscellaneous Reactions of Methylenephosphoranes -- 3 Reactions of Phosphonate Anions -- 4 Selected Applications in Synthesis -- Carbohydrates -- Carotenoids and Related Compounds -- β-Lactam Antibiotics -- Leukotrienes and Related Compounds. -- Pheromones -- Prostaglandins -- Miscellaneous Applications -- Chapter 9 Cyclic and Polymeric Phosphazenes* -- 1 Introduction -- 2 Cyclic Phosphazenes -- Introduction -- Formation of the Ring Skeleton -- Reactions with Amines -- Reactions with Alcohols -- Hydrolysis and Related Phenomena -- Reactions with Organometallic Reagents -- Miscellaneous Substitution Reactions -- Theory and Spectra -- Physiologically Active Compounds -- Miscellaneous Applications -- 3 Polyphosphazenes -- Introduction -- Poly[bis(halo)phosphazenes] -- Poly[(organophosphazenes)] -- Polyphosphazenes as Carriers for Active Groups -- 4 X-Ray Molecular Structure Determinations -- Chapter 10 Physical Methods -- 1 Nuclear Magnetic Resonance Spectroscopy. , Biological Aspects -- Chemical Shifts and Shielding Effects -- Anisotropy Effects -- Phosphorus-31 -- δp of n2 compounds -- δp of n3 compounds -- δp of n4 compounds -- δp of n5 compounds -- δp of n6 compounds -- Hydrogen-1 -- Carbon-13 -- Nitrogen-15 and Oxygen-17 -- Fluorine-19 -- Solvation and Shift Reagents -- Variable Temperature Studies -- Studies of Configuration -- Spin-Spin Coupling -- J(PP) and J(PM) -- J(PF) -- J(P17O) and J(P15N) -- J(PC) -- J(PH) -- Relaxation, CIDNP, and N.Q.R. -- Relaxation -- CIDNP -- N.Q.R. -- 2 Electron Spin Resonance Spectroscopy -- 3 Vibrational and Rotational Spectroscopy -- Bond Assignments -- Bonding -- Stereochemistry -- Rotational Spectra -- 4 Electronic Spectroscopy -- Absorption Spectroscopy -- Photoelectron Spectroscopy -- Emission Spectroscopy -- 5 Diffraction -- X-Ray Diffraction -- Electron Diffraction -- 6 Dipole Moments, Kerr Effects, and Polarography -- 7 Mass Spectrometry -- 8 Acidities and Basicities -- 9 Chromatography -- Gas-Liquid Chromatography -- Thin-layer and Paper Chromatography -- High Performance Liquid Chromatography -- Ion Exchange and Electrophoresis -- Surface Properties -- Author Index.