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  • 1
    Electronic Resource
    Electronic Resource
    Modified Combustion Procedure for Determining Carbon and Hydrogen in Certain Organometallic Compounds (1956)
    s.l. : American Chemical Society
    Analytical chemistry 28 (1956), S. 1172-1174 
    Details
    ISSN: 1520-6882
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/ac60115a031
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  • 2
    Electronic Resource
    Electronic Resource
    Oxidative damage increases with age in a canine model of human brain aging (2002)
    Oxford, UK : Blackwell Science Ltd
    Journal of neurochemistry 82 (2002), S. 0 
    Details
    ISSN: 1471-4159
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: We assayed levels of lipid peroxidation, protein carbonyl formation, glutamine synthetase (GS) activity and both oxidized and reduced glutathione to study the link between oxidative damage, aging and β-amyloid (Aβ) in the canine brain. The aged canine brain, a model of human brain aging, naturally develops extensive diffuse deposits of human-type Aβ. Aβ was measured in immunostained prefrontal cortex from 19 beagle dogs (4–15 years). Increased malondialdehyde (MDA), which indicates increased lipid peroxidation, was observed in the prefrontal cortex and serum but not in cerebrospinal fluid (CSF). Oxidative damage to proteins (carbonyl formation) also increased in brain. An age-dependent decline in GS activity, an enzyme vulnerable to oxidative damage, and in the level of glutathione (GSH) was observed in the prefrontal cortex. MDA level in serum correlated with MDA accumulation in the prefrontal cortex. Although 11/19 animals exhibited Aβ, the extent of deposition did not correlate with any of the oxidative damage measures, suggesting that each form of neuropathology accumulates in parallel with age. This evidence of widespread oxidative damage and Aβ deposition is further justification for using the canine model for studying human brain aging and neurodegenerative diseases.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1471-4159.2002.00969.x
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  • 3
    Electronic Resource
    Electronic Resource
    Di-t-butylberyllium and Beryllium Hydride1 (1957)
    s.l. : American Chemical Society
    Journal of the American Chemical Society 79 (1957), S. 3687-3689 
    Details
    ISSN: 1520-5126
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/ja01571a023
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  • 4
    Electronic Resource
    Electronic Resource
    Effects of air ions on the neonatal growth of laboratory rats (1981)
    Springer
    International journal of biometeorology 25 (1981), S. 323-329 
    Details
    ISSN: 1432-1254
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geography , Physics
    Notes: Abstract The effect of continuous positive and negative ionization on the growth of rats during the pre and post natal period, up to 10 weeks of age was investigated. It was found that continuous exposure to 1.0×104 pos. ions/ml had no detrimental effect on the animals at any stage of their development. In contrast, exposure to 1.0×104 neg. ions/ml, during gestation and the early post natal period, resulted in some adverse effects on growth and development. However, when exposure to this level of negative ions began at the time of weaning, no adverse effects were observed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02198247
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  • 5
    Electronic Resource
    Electronic Resource
    Depth profiles of plankton, particulate organic matter and microbial activity in the eastern Canadian Arctic during summer (1987)
    Springer
    Polar biology 7 (1987), S. 207-224 
    Details
    ISSN: 1432-2056
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary Deep profiles of particulate organic matter, microplankton (phytoplankton and bacteria), zooplankton and their metabolic activities were investigated during two summer voyages to the eastern Canadian Arctic. Magnitudes and depth distributions were similar in many respects to observations from temperate and tropical waters. Strong gradients in most properties were observed in the upper 50–100 m and subsurface maxima were generally associated with the upper mixed-layer (〉50 m). In addition to the general vertical decreases in plankton biomass and metabolic activity there was evidence for both rapid transport (sinking) of organic matter and for enhanced (above background) levels of microbial metabolic activity in deep waters (〉500 m). Zooplankton depth distributions differed from the pattern generally observed at lower latitudes; in the Arctic, zooplankton abundance decreased to a lesser degree with depth than particulate organics and microplankton. The overwintering behavior of high-latitude zooplankton appeared to be the best explanation for their relatively high abundance at depth. Despite this, however, zooplankton apparently contributed little to the total column community metabolism.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00287417
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  • 6
    Electronic Resource
    Electronic Resource
    A rapid method for the purification of octopine dehydrogenase for the determination of cell metabolites (1979)
    Springer
    Cellular and molecular life sciences 35 (1979), S. 304-305 
    Details
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Unlike other NAD+-dependent dehydrogenases, octopine dehydrogenase was not bound by blue Sepharose. A rapid 2-step purification procedure (gel filtration on Sephadex G-100 followed by affinity chromatography on blue Sepharose) resulted in a final preparation of octopine dehydrogenase which had a sp. act. of 65 units/mg protein and was free of contaminating NAD+-oxidoreductases. This preparation has been used successfully for the estimation of phospho-L-arginine, L-arginine and octopine in perchloric acid extracts.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01964314
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  • 7
    Electronic Resource
    Electronic Resource
    Effects of negative air ions on growth and regeneration in the Indian stick insect (1983)
    Springer
    International journal of biometeorology 27 (1983), S. 165-171 
    Details
    ISSN: 1432-1254
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geography , Physics
    Notes: Abstract Nymphs of the Indian stick insectCarausius morosus, Brunner were maintained at ambient or 4.2×104 negative ions per c.c. Regenerative processes were initiated in each nymph by stimulation of the leg autotomy reflex. Aspects of growth, the moulting cycles and leg renewal were studied. Few significant weight differences were found between the insects growing in the control and ionized environments. However, the growth curve of the ion treated insects was irregular, unlike that of the control group which increased smoothly. Slight delays in the intermoult period and in the rate of leg regeneration were also noted in those insects exposed to negative ions. Previous workers have shown significant increases in the growth of some insects exposed to negative ions. These new results show no significant effects but suggest growth may be inhibited.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02185748
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  • 8
    Electronic Resource
    Electronic Resource
    The effect of negative air ionization on the growth of four generations of laboratory rats (1984)
    Springer
    International journal of biometeorology 28 (1984), S. 163-168 
    Details
    ISSN: 1432-1254
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geography , Physics
    Notes: Abstract Initial work indicated an inhibition of pre-weaning growth in the first generation of rats born and raised at high negative ion levels. This effect, however, was not carried through to the successive generations. Negative ionization had little apparent effect on post-weaning growth throughout the four generations studied.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02191730
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  • 9
    Electronic Resource
    Electronic Resource
    The effect of positive air ions on reproduction and growth in laboratory rats (1986)
    Springer
    International journal of biometeorology 30 (1986), S. 69-75 
    Details
    ISSN: 1432-1254
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geography , Physics
    Notes: Abstract The aim of the present investigation was to determine the growth rates, reproductive success and early mortality of laboratory rats maintained at 10,000 positive ions/ml over two generations. These findings were compared with those from animals maintained at ambient ion levels. The present work indicates that positive ions do not have any adverse effects on the reproductive capabilities or the growth of laboratory rats. In contrast it is shown that exposure to elevated levels of positive ions promotes overall growth, particularly in male rats. This action of positive ions increases with each successive generation exposed to the ions. It is suggested that the growth promoting effect of positive ions may be mediated via some modulation of the endocrine system.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02192062
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  • 10
    Electronic Resource
    Electronic Resource
    Physiological adaptations of an under-ice population of Pseudocalanus in Barrow Strait (N.W.T) to increasing food supply in spring (1990)
    Springer
    Polar biology 10 (1990), S. 561-570 
    Details
    ISSN: 1432-2056
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary Zooplankton and water samples were collected at weekly intervals between April 25 and May 30, 1986 in Barrow Strait, N.W.T. (Canadian Arctic Archipelago). In tows from 0–30 m, the zooplankton community (〉202 μm) was dominated by Pseudocalanus. The population was apparently growing and developing as shown by an increase in the proportion of adults (stage VI) and decreases in the proportion of stages III, IV, and V as the season progressed. Respiration and excretion rates of the Pseudocalanus populations were probably linked, there being an immediate increase in excretion rate, accompanying an increase in feeding rate when chlorophyll concentrations increased, which was followed by a smaller increase in respiration rate after a time lag. Hence, there was a large decrease in the O∶N ratio. Increased metabolism coincided with changes in the population structure, as did protease and bodily protein, but could not be clearly linked to dietary acclimation. Only laminarinase activity could be statistically related to an identifiable fraction of potential nutritional value in the water, particulate soluble carbohydrate, but neither showed overall seasonal change.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00239367
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