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  • 1
    In: Scientific Reports, Springer Science and Business Media LLC, Vol. 13, No. 1 ( 2023-05-24)
    Abstract: Secondary transports of patients from one hospital to another are indicated for medical reasons or to address local constraints in capacity. In particular, interhospital transports of critically ill infectious patients present a logistical challenge and can be key in the effective management of pandemic situations. The state of Saxony in Germany has two characteristics that allow for an extensive evaluation of secondary transports in the pandemic year 2020/2021. First, all secondary transports are centrally coordinated by a single institution. Second, Saxony had the highest SARS-CoV-2 infection rates and the highest COVID-19 associated mortality in Germany. This study evaluates secondary interhospital transports from March 2019 to February 2021 in Saxony with a detailed analysis of transport behaviour during the pandemic phase March 2020 to February 2021. Our analysis includes secondary transports of SARS-CoV-2 patients and compares them to secondary transports of non-infectious patients. In addition, our data show differences in demographics, SARS-CoV-2- incidences, ICU occupancy of COVID-19 patients, and COVID-19 associated mortality in all three regional health clusters in Saxony. In total, 12,282 secondary transports were analysed between March 1st, 2020 and February 28th, 2021, of which 632 were associated with SARS-CoV-2 (5.1%) The total number of secondary transports changed slightly during the study period March 2020 to February 2021. Transport capacities for non-infectious patients were reduced due to in-hospital and out-of-hospital measures and could be used for transport of SARS-CoV-2 patients. Infectious transfers lasted longer despite shorter distance, occurred more frequently on weekends and transported patients were older. Primary transport vehicles were emergency ambulances, transport ambulances and intensive care transport vehicles. Data analysis based on hospital structures showed that secondary transports in correlation to weekly case numbers depend on the hospital type. Maximum care hospitals and specialized hospitals show a maximum of infectious transports approximately 4 weeks after the highest incidences. In contrast, standard care hospitals transfer their patients at the time of highest SARS-CoV-2 case numbers. Two incidence peaks were accompanied by two peaks of increased secondary transport. Our findings show that interhospital transfers of SARS-CoV-2 and non-SARS-CoV-2 patients differ and that different hospital care levels initiated secondary transports at different times during the pandemic.
    Type of Medium: Online Resource
    ISSN: 2045-2322
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2023
    detail.hit.zdb_id: 2615211-3
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  • 2
    Online Resource
    Online Resource
    Informa UK Limited ; 2012
    In:  Critical Reviews in Environmental Science and Technology Vol. 42, No. 8 ( 2012-04-15), p. 857-890
    In: Critical Reviews in Environmental Science and Technology, Informa UK Limited, Vol. 42, No. 8 ( 2012-04-15), p. 857-890
    Type of Medium: Online Resource
    ISSN: 1064-3389 , 1547-6537
    Language: English
    Publisher: Informa UK Limited
    Publication Date: 2012
    detail.hit.zdb_id: 2030115-7
    detail.hit.zdb_id: 1156240-7
    SSG: 12
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  • 3
    Online Resource
    Online Resource
    IWA Publishing ; 2012
    In:  Journal of Water, Sanitation and Hygiene for Development Vol. 2, No. 3 ( 2012-09-01), p. 146-156
    In: Journal of Water, Sanitation and Hygiene for Development, IWA Publishing, Vol. 2, No. 3 ( 2012-09-01), p. 146-156
    Abstract: Investigations and established causal relationship of waterborne outbreaks (WOs) from developing countries and countries in transition are sparse and mainly centered on agents, such as from Vibrio cholera and Shigella dysenteriae. Information, however, prevails in countries like Armenia with an epidemiological system in place. Groundwater is the main drinking water source (96%); water is delivered intermittently 12–14 hours per day. In 2005 about 7% of all infant deaths were attributed to intestinal infectious diseases. Recorded information on WOs and supply systems (1992–2010) was obtained from published official sources, from ‘gray-literature reports’, primary data collection from statistical records and through personal communication. Epidemiological descriptive analysis was made and Geographical Information System (GIS) applied for results visualization. In-depth outbreak analysis was conducted on selected cases. Overall, 104 WOs caused by different etiological agents were revealed. The main drinking water source in areas where outbreaks occurred was the centralized water supplies (69.2%) based on GIS mapping. The major cause of outbreaks was the cross-contamination of drinking-water distribution by wastewater. In Armenia the main areas to be addressed for the future are: service quality, source protection, delivery interruption and subsequent microbial contamination.
    Type of Medium: Online Resource
    ISSN: 2043-9083 , 2408-9362
    Language: English
    Publisher: IWA Publishing
    Publication Date: 2012
    detail.hit.zdb_id: 2642398-4
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  • 4
    In: Das Gesundheitswesen, Georg Thieme Verlag KG, Vol. 81, No. 02 ( 2019-02), p. 82-87
    Abstract: Einführung Die Bedeutung von multiresistenten gramnegativen Erregern als Ursache von lebensbedrohlichen Infektionen lässt dem Antibiotic Stewardship höchste Bedeutung zukommen. Ziel Erkennen von Schwächen bei Antibiotikaverschreibungen in Krankenhäusern und Vergleich zwischen 2009 und 2014. Methoden Ein Fragebogen wurde 2014 an alle 380 Ärzte von 7 Krankenhäusern, der Grund-, Regel- und Maximalversorgung verteilt. Erfasst wurden berufliche Entwicklung, Funktion, Kenntnisstand und Vorhandensein und Einsatz von Regeln zum Umgang mit Antibiotika. Die 119 beantworteten Fragebögen von 2014 wurden mit den 3613 aus 2009 verglichen. Ergebnisse 31% der Fragebögen wurden zurückgeschickt, 53,8% von Assistenzärzten, die Hälfte ohne Facharztanerkennung. 32,8% wurden von Oberärzten, 12,6% von Chefärzten beantwortet. 22.6% waren Internisten, 18,4% Chirurgen, 10,9% Urologen und 9,2% Anaesthesisten. Mehrheitlich wurden Antibiotika täglich verschrieben, von Assistenzärzten zu 66%. 23% der Assistenzärzte gaben an, täglich andere Kollegen zu beraten und 61% mind. 1-mal in der Woche. Der häufigste Anlass hierfür ist die perioperative Antibiotikaprophylaxe (35), der Harnwegsinfekt (32) und die Pneumonie (29). Die Standarddauer der Gabe war 7 Tage bei Pneumonie, 5 Tage beim Harnwegsinfekt und 1 Tag bei der perioperativen Antibiotikaprophylaxe.In fast der Hälfte der Fälle wurde die perioperative Antibiotikaprophylaxe auf 3, 5, 7,8 und 10 Tage ausgedehnt. 93,3% der Ärzte berichteten Antibiotikaleitlinien des eigenen Hauses oder von Fachgesellschaften zu benutzen. Nur 59,3% wussten über die Resistenzen an ihrem Arbeitsplatz Bescheid. 52,1% verschreiben Breitspektrumantibiotika ohne Rücksprache mit dem Oberarzt oder Chefarzt. Im Vergleich zu 2009 sind Kenntnisstand über Antibiotikaresistenzen des Hauses, Benutzung von Leitlinien und Rücksprache mit Ober- bzw. Chefarzt jeweils um ca. 5% angestiegen. Schlussfolgerung Trotz Verbesserung im Vergleich zu 2009 kannten 38,9% der Befragten die antibiotische Resistenzlage in ihrem Haus nicht und die Hälfte aller Chirurgen setzte die perioperative Prophylaxe länger als 24 Stunden ein. Da die Bereitschaft antibiotische Leitlinien zu benutzen mit 93,3% sehr hoch ist, sollten diese ausgeweitet und regelmäßig an die Resistenzlage angepasst werden. Ferner sollte die perioperative Antibiotikaprophylaxe länger als einen Tag wegen der zusätzlichen Nebenwirkungen ohne weiteren Benefit kritisch hinterfragt werden.
    Type of Medium: Online Resource
    ISSN: 0941-3790 , 1439-4421
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    Language: German
    Publisher: Georg Thieme Verlag KG
    Publication Date: 2019
    detail.hit.zdb_id: 1101426-X
    SSG: 20,1
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  • 5
    Online Resource
    Online Resource
    Elsevier BV ; 2020
    In:  International Journal of Hygiene and Environmental Health Vol. 226 ( 2020-05), p. 113506-
    In: International Journal of Hygiene and Environmental Health, Elsevier BV, Vol. 226 ( 2020-05), p. 113506-
    Type of Medium: Online Resource
    ISSN: 1438-4639
    Language: English
    Publisher: Elsevier BV
    Publication Date: 2020
    detail.hit.zdb_id: 2039765-3
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  • 6
    In: SSRN Electronic Journal, Elsevier BV
    Type of Medium: Online Resource
    ISSN: 1556-5068
    Language: English
    Publisher: Elsevier BV
    Publication Date: 2020
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  • 7
    Online Resource
    Online Resource
    Springer Science and Business Media LLC ; 2020
    In:  Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschutz Vol. 63, No. 10 ( 2020-10), p. 1231-1240
    In: Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschutz, Springer Science and Business Media LLC, Vol. 63, No. 10 ( 2020-10), p. 1231-1240
    Abstract: Pediatric outpatients with respiratory tract infections (RTIs) comprise an important target population for antibiotic stewardship (ABS) intervention. Objectives The aim of this qualitative study was to determine which clinical and contextual factors have a significant impact on antibiotic therapy (ABT) in pediatric patients with RTIs. Materials and methods An online survey was developed and carried out in Germany in cooperation with the Federal Association of Pediatricians and the German Society for Pediatric Infectious Diseases. Pediatricians and general practitioners were invited to participate. Results The survey yielded 555 complete response data sets. Diagnostic uncertainty, time constraints for repeated consultations, and fear of complications were identified by 50% of both medical specialties as contextual factors fostering ABT. The risk of serious complications (e.g., mastoiditis) was overestimated by the majority of participants. More than 40% of respondents lacked knowledge concerning official guidelines, and RTIs with fever lasting longer than three days appeared to be an important criterion for ABT for 30–40%. Fewer than 60% of physicians were using a point-of-care device to determine C‑reactive protein. Conclusion Although most participants acknowledged the growing prevalence of antibiotic-resistant pathogens as an important problem, this survey identifies targets for ABS in pediatric outpatients with RTIs. Ongoing education and training (e.g., better communication strategies in response to parental concerns) should become mandatory for those who prescribe ABT for children with RTIs.
    Type of Medium: Online Resource
    ISSN: 1436-9990 , 1437-1588
    Language: German
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2020
    detail.hit.zdb_id: 1470303-8
    SSG: 20,1
    SSG: 8,1
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  • 8
    Online Resource
    Online Resource
    MDPI AG ; 2023
    In:  International Journal of Environmental Research and Public Health Vol. 20, No. 3 ( 2023-01-18), p. 1809-
    In: International Journal of Environmental Research and Public Health, MDPI AG, Vol. 20, No. 3 ( 2023-01-18), p. 1809-
    Abstract: Nosocomial outbreaks require quick epidemiological clarification of possible chains of infection, since the pathogen usually has a head start that has to be caught up. Identification of people and areas at risk is crucial for efficient confinement. This paper describes a concept which can be applied to healthcare settings. The application skips the time-consuming and imperfect reconstruction of direct and indirect contacts. Indoor mobility of people and devices are instead measured precisely, and the mobility history is used to construct a spatio-temporal ‘landscape of infection’. This landscape allows for the calculation of a modelled ‘contamination landscape’ (CL) adding location-based prolongation of infectivity. In that way, the risk per person can be derived in case of an outbreak. The CL concept is extremely flexible and can be adapted to various pathogen-specific settings. The combination of advanced measurements and specific modelling results in an instant list of possible recipients who need to be examined directly. The modelled, pathogen-specific parameters can be adjusted to get as close as possible to the results of mass screenings.
    Type of Medium: Online Resource
    ISSN: 1660-4601
    Language: English
    Publisher: MDPI AG
    Publication Date: 2023
    detail.hit.zdb_id: 2175195-X
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  • 9
    Online Resource
    Online Resource
    Informa UK Limited ; 2012
    In:  Critical Reviews in Environmental Science and Technology Vol. 42, No. 4 ( 2012-02-15), p. 378-411
    In: Critical Reviews in Environmental Science and Technology, Informa UK Limited, Vol. 42, No. 4 ( 2012-02-15), p. 378-411
    Type of Medium: Online Resource
    ISSN: 1064-3389 , 1547-6537
    Language: English
    Publisher: Informa UK Limited
    Publication Date: 2012
    detail.hit.zdb_id: 2030115-7
    detail.hit.zdb_id: 1156240-7
    SSG: 12
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  • 10
    Online Resource
    Online Resource
    Elsevier BV ; 2017
    In:  International Journal of Hygiene and Environmental Health Vol. 220, No. 7 ( 2017-10), p. 1110-1123
    In: International Journal of Hygiene and Environmental Health, Elsevier BV, Vol. 220, No. 7 ( 2017-10), p. 1110-1123
    Type of Medium: Online Resource
    ISSN: 1438-4639
    Language: English
    Publisher: Elsevier BV
    Publication Date: 2017
    detail.hit.zdb_id: 2039765-3
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