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  • 1
    Online Resource
    Online Resource
    New York :Oxford University Press, Incorporated,
    Keywords: Virus diseases - Transmission. ; Electronic books.
    Description / Table of Contents: Introduction: Virus Basics and the Concept of Viral FitnessJaap Goudsmit1. As Natural As Breathing: The Flu Virus2. Farming and Feeding the Hungry: Plant Viruses and Human Enteroviruses3. Raising Cattle and Eating Meat: Rinderpest, Measles, and Mad Cow Disease4. Slaking Our Thirst: The Cholera Bacteria and Its Toxic Viruses5. Weathering Storms and Droughts: West Nile Virus and Others6. Getting Lucky With a Faulty Gene: Escape from Simple Retroviruses7 Taking Chances With Sex: The Herpes and Papova Viruses.8. Risking Death with Sex: The AIDS Virus9. Warring Against Humans and Other Animals:Smallpox, Monkeypox, and Others10. Raiding the Wild For Delicacies: The SARS VirusEpilogueGlossaryBibliographyIndex.
    Type of Medium: Online Resource
    Pages: 1 online resource (204 pages)
    Edition: 1st ed.
    ISBN: 9780198029922
    DDC: 614.5/8
    Language: English
    Note: Intro -- Contents -- Introduction: Virus Basics and the Concept of Viral Fitness -- 1 As Natural As Breathing: The Flu Virus -- 2 Farming and Feeding the Hungry: Plant Viruses and Human Enteroviruses -- 3 Raising Cattle and Eating Meat: Rinderpest, Measles, and Mad Cow Disease -- 4 Slaking Our Thirst: The Cholera Bacteria and Its Toxic Viruses -- 5 Weathering Storms and Droughts: West Nile Virus and Others -- 6 Getting Lucky With a Faulty Gene: Escape from Simple Retroviruses -- 7 Taking Chances With Sex: The Herpes and Papova Viruses -- 8 Risking Death with Sex: The AIDS Virus -- 9 Warring Against Humans and Other Animals: Smallpox, Monkeypox, and Others -- 10 Raiding the Wild For Delicacies: The SARS Virus -- Epilogue -- Glossary -- A -- B -- C -- D -- E -- F -- G -- H -- K -- L -- M -- N -- O -- P -- Q -- R -- S -- T -- V -- W -- X -- Z -- Bibliography -- Index -- A -- B -- C -- D -- E -- F -- G -- H -- I -- J -- K -- M -- N -- O -- P -- Q -- R -- S -- T -- U -- V -- W -- X.
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Journal of molecular evolution 40 (1995), S. 173-180 
    ISSN: 1432-1432
    Keywords: African monkeys ; mtDNA ; 12S rRNA gene ; Phylogeny
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract The suborder Anthropoidea of the primates has traditionally been divided in three superfamilies: the Hominoidea (apes and humans) and the Cercopithecoidea (Old World monkeys), together comprising the infraorder Catarrhini, and the Ceboidea (New World monkeys) belonging to the infraorder Platyrrhini. We have sequenced an approximately 390-base-pair part of the mitochondrial 12S rRNA gene for 26 species of the major groups of African monkeys and apes and constructed an extensive phylogeny based upon DNA evidence. Not only is this phylogeny of great importance in classification of African guenons, but it also suggests rearrangements in traditional monkey taxonomy and evolution. Baboons and mandrills were found to be not directly related, while we could confirm that the known four superspecies of mangabeys do not form a monophyletic group, but should be separated into two genera, one clustering with baboons and the other with mandrills. Patas monkeys are clearly related to members of the genus Cercopithecus despite their divergence in build and habitat, while the talapoin falls outside the Cercopithecus clade (including the patas monkey).
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1432-1432
    Keywords: Nuclear integrations ; Mitochondrial 12S rRNA gene ; Ancient DNA ; primates
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Monkey mummy bones and teeth originating from the North Saqqara Baboon Galleries (Egypt), soft tissue from a mummified baboon in a museum collection, and nineteenth/twentieth-century skin fragments from mangabeys were used for DNA extraction and PCR amplification of part of the mitochondrial 12S rRNA gene. Sequences aligning with the 12S rRNA gene were recovered but were only distantly related to contemporary monkey mitochondrial 12S rRNA sequences. However, many of these sequences were identical or closely related to human nuclear DNA sequences resembling mitochondrial 12S rRNA (isolated from a cell line depleted in mitochondria) and therefore have to be considered contamination. Subsequently in a separate study we were able to recover genuine mitochondrial 12S rRNA sequences from many extant species of nonhuman Old World primates and sequences closely resembling the human nuclear integrations. Analysis of all sequences by the neighbor-joining (NJ) method indicated that mitochondrial DNA sequences and their nuclear counterparts can be divided into two distinct clusters. One cluster contained all temporary cytoplasmic mitochondrial DNA sequences and approximately half of the monkey nuclear mitochondriallike sequences. A second cluster contained most human nuclear sequences and the other half of monkey nuclear sequences with a separate branch leading to human and gorilla mitochondrial and nuclear sequences. Sequences recovered from ancient materials were equally divided between the two clusters. These results constitute a warning for when working with ancient DNA or performing phylogenetic analysis using mitochondrial DNA as a target sequence: Nuclear counterparts of mitochondrial genes may lead to faulty interpretation of results.
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 1546-170X
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Medicine
    Notes: [Auszug] Multiphasic HIV decrease in individuals treated with anti-retroviral drugs has been modeled as the independent decay, with different half-lives, of distinct pools of cells infected before the initiation of treatment. We analyzed the kinetics of plasma HIV RNA in individuals receiving combinations ...
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature 360 (1992), S. 215-216 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] SIR - Although human immunodeficiency virus-1 (HIV-1) has been demonstrated to infect an ever-increasing array of human cell types, isolation and localization of the virus in vivo suggests that cells of the lympho-reticular system are predominantly affected. Understanding the viral-specific ...
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature 346 (1990), S. 801-801 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] SIR-The role of human immunodeficiency virus type 1 (HIV-1) in the pathogenesis of Kaposi's sarcoma is thought to be indirect. HIV-1 sequences are absent in DNA from cultured Kaposi's sarcoma-derived cells', and transgenic mice carrying the tat gene and developing Kaposi's-like lesions express tat ...
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    [s.l.] : Macmillan Magazines Ltd.
    Nature 400 (1999), S. 325-326 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] The moment in history when subtypes of the human immunodeficiency virus HIV-1 became distinguishable is hotly debated,. Zhu et al. have provided a unique HIV-1 sequence from 1959, known as ZR59. Based on the position of ZR59 in phylogenetic trees and its distance from the common node of the ...
    Type of Medium: Electronic Resource
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  • 8
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] A common viral immune evasion strategy involves mutating viral surface proteins in order to evade host neutralizing antibodies. Such immune evasion tactics have not previously been intentionally applied to the development of novel viral gene delivery vectors that overcome the critical problem ...
    Type of Medium: Electronic Resource
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  • 9
    ISSN: 1432-1203
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The genetic polymorphism of group-specific component (GC) was investigated with isoelectric focusing in 351 homosexual men at risk for HIV infection, 96 male patients with AIDS, and 86 heterosexual controls. No significant differences in GC phenotype distribution were seen between controls and any of the at risk groups or patients, neither between HIV-Ab-positive/Ag-negative and HIV-Ab-positive/Ag-positive homosexual men nor between HIV-Ab-positive/Ag-positive homosexual men and AIDS patients, suggesting that the GC system is not involved in the infective susceptibility or progression of HIV infection to AIDS-related complex and AIDS.
    Type of Medium: Electronic Resource
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