Notes: Summary Intraseasonal variation of tropical convergence zones (TCZ) is studied focussing on the three major features of the TCZ over the Indian longitudes during the summer monsoon viz. (i) the oscillation between active and weak spells, (ii) the occurrence of two favourable zones — one over the equatorial oceans and another over the heated continent and (iii) poleward propagations of the oceanic TCZ onto the heated continent. An observational study of the intraseasonal variation over different parts of the tropics has shown that the first feature may be an ubiquitous feature of the TCZ variations, the second occurs only over the Asian summer and winter monsoon zones, and the third only over the Asian summer monsoon. Analysis of a simple monsoon model has revealed that poleward propagation occurs in the presence of a meridional surface temperature gradient because the convective heating is asymmetric, with more heating on the poleward side. Preliminary analysis of the T-21 version of the ECMWF model has shown that it is capable of simulating the three major features of the intraseasonal variation of the TCZ over the Indian longitudes during the summer monsoon.

Notes: Summary Observational studies indicate that the convective activity of the monsoon systems undergo intraseasonal variations with multi-week time scales. The zone of maximum monsoon convection exhibits substantial transient behavior with successive propagating from the North Indian Ocean to the heated continent. Over South Asia the zone achieves its maximum intensity. These propagations may extend over 3000 km in latitude and perhaps twice the distance in longitude and remain as coherent entities for periods greater than 2–3 weeks. Attempts to explain this phenomena using simple ocean-atmosphere models of the monsoon system had concluded that the interactive ground hydrology so modifies the total heating of the atmosphere that a steady state solution is not possible, thus promoting lateral propagation. That is, the ground hydrology forces the total heating of the atmosphere and the vertical velocity to be slightly out of phase, causing a migration of the convection towards the region of maximum heating. Whereas the lateral scale of the variations produced by the Webster (1983) model were essentially correct, they occurred at twice the frequency of the observed events and were formed near the coastal margin, rather than over the ocean. Webster's (1983) model used to pose the theories was deficient in a number of aspects. Particularly, both the ground moisture content and the thermal inertia of the model were severely underestimated. At the same time, the sea surface temperatures produced by the model between the equator and the model's land-sea boundary were far too cool. Both the atmosphere and the ocean model were modified to include a better hydrological cycle and ocean structure. The convective events produced by the modified model possessed the observed frequency and were generated well south of the coastline. The improved simulation of monsoon variability allowed the hydrological cycle feedback to be generalized. It was found that monsoon variability was constrained to lie within the bounds of a positive gradient of aconvective intensity potential (I). The function depends primarily on the surface temperature, the availability of moisture and the stability of the lower atmosphere which varies very slowly on the time scale of months. The oscillations of the monsoon perturb the mean convective intensity potential causing local enhancements of the gradient. These perturbations are caused by the hydrological feedbacks, discussed above, or by the modification of the air-sea fluxes caused by variations of the low level wind during convective events. The final result is the slow northward propagation of convection within an even slower convective regime. The ECMWF analyses show very similar behavior of the convective intensity potential. Although it is considered premature to use the model to conduct simulations of the African monsoon system, the ECMWF analysis indicates similar behavior in the convective intensity potential suggesting, at least, that the same processes control the low frequency structure of the African monsoon. The implications of the hypotheses on numerical weather prediction of monsoon phenomenon are discussed.

Notes: Abstract  We present an analysis of the seasonal precipitation associated with the African, Indian and the Australian-Indonesian monsoon and the interannual variation of the Indian monsoon simulated by 30 atmospheric general circulation models undertaken as a special diagnostic subproject of the Atmospheric Model Intercomparison Project (AMIP). The seasonal migration of the major rainbelt observed over the African region, is reasonably well simulated by almost all the models. The Asia West Pacific region is more complex because of the presence of warm oceans equatorward of heated continents. Whereas some models simulate the observed seasonal migration of the primary rainbelt, in several others this rainbelt remains over the equatorial oceans in all seasons. Thus, the models fall into two distinct classes on the basis of the seasonal variation of the major rainbelt over the Asia West Pacific sector, the first (class I) are models with a realistic simulation of the seasonal migration and the major rainbelt over the continent in the boreal summer; and the second (class II) are models with a smaller amplitude of seasonal migration than observed. The mean rainfall pattern over the Indian region for July-August (the peak monsoon months) is even more complex because, in addition to the primary rainbelt over the Indian monsoon zone (the monsoon rainbelt) and the secondary one over the equatorial Indian ocean, another zone with significant rainfall occurs over the foothills of Himalayas just north of the monsoon zone. Eleven models simulate the monsoon rainbelt reasonably realistically. Of these, in the simulations of five belonging to class I, the monsoon rainbelt over India in the summer is a manifestation of the seasonal migration of the planetary scale system. However in those belonging to class II it is associated with a more localised system. In several models, the oceanic rainbelt dominates the continental one. On the whole, the skill in simulation of excess/deficit summer monsoon rainfall over the Indian region is found to be much larger for models of class I than II, particularly for the ENSO associated seasons. Thus, the classification based on seasonal mean patterns is found to be useful for interpreting the simulation of interannual variation. The mean rainfall pattern of models of class I is closer to the observed and has a higher pattern correlation coefficient than that of class II. This supports Sperber and Palmer’s (1996) result of the association of better simulation of interannual variability with better simulation of the mean rainfall pattern. The hypothesis, that the skill of simulation of the interannual variation of the all-India monsoon rainfall in association with ENSO depends upon the skill of simulation of the seasonal variation over the Asia West Pacific sector, is supported by a case in which we have two versions of the model where NCEP1 is in class II and NCEP2 is in class I. The simulation of the interannual variation of the local response over the central Pacific as well as the all-India monsoon rainfall are good for NCEP2 and poor for NCEP1. Our results suggest that when the model climatology is reasonably close to observations, to achieve a realistic simulation of the interannual variation of all-India monsoon rainfall associated with ENSO, the focus should be on improvement of the simulation of the seasonal variation over the Asia West Pacific sector rather than further improvement of the simulation of the mean rainfall pattern over the Indian region.

Notes: Abstract The aim of this paper is to provide a summary of clinical findings regarding the safety of tacrolimus in pregnancy. From 1992 to 1998 data were collected on 100 pregnancies from 84 mothers who received tacrolimus systemically; 83 cases of solid organ transplantation, and 1 case of Behçet's disease. Maternal mean age at conception was 28 years and pregnancy outcome was live birth in 68 %, spontaneous abortion in 12 %, induced abortion in 12 %, stillbirth/perinatal death in 3 %, ongoing pregnancy in 2 %, and lost to follow up in 3 %. Fifty-nine percent of the neonates were delivered prematurely ( 〈 37 weeks of gestation). Birth weight was appropriate for the gestational age in 90 % of the cases. Malformations occurred in 4 neonates: case 1, meningocele and urogenital defects; case 2, alcoholic embryopathy; case 3, ear defect, cleft palate and hypospadia; case 4, multicystic dysplastic kidney. There was no consistent pattern of malformations and 2 mothers subsequently delivered a healthy neonate while on tacrolimus therapy. Nearly 70 % of pregnancies following systemic tacrolimus administration resulted in a favourable outcome without any significant effect on intrauterine growth. The incidence of malformations was similar to that reported with other immunosuppressants in transplant recipients.