GLORIA

GEOMAR Library Ocean Research Information Access

X

Ihre E-Mail wurde erfolgreich gesendet. Bitte prüfen Sie Ihren Maileingang.

Leider ist ein Fehler beim E-Mail-Versand aufgetreten. Bitte versuchen Sie es erneut.

Vorgang fortführen?

Exportieren
Filter
Materialart
Verlag/Herausgeber
Person/Organisation
Sprache
Erscheinungszeitraum
FID
Fachgebiete(RVK)
  • 1
    Online-Ressource
    Online-Ressource
    The CanMars Mars Sample Return analogue mission
    Elsevier BV ; 2019
    In:  Planetary and Space Science Vol. 166 ( 2019-02), p. 110-130
    Details
    In: Planetary and Space Science, Elsevier BV, Vol. 166 ( 2019-02), p. 110-130
    Materialart: Online-Ressource
    ISSN: 0032-0633
    URL: Article
    DOI: 10.1016/j.pss.2018.07.011
    Sprache: Englisch
    Verlag: Elsevier BV
    Publikationsdatum: 2019
    ZDB Id: 2012795-9
    SSG: 16,12
    Standort Signatur Einschränkungen Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    Online-Ressource
  • 2
    Online-Ressource
    Online-Ressource
    Fetal brain activity and hemodynamic response to a vibroacoustic stimulus
    Wiley ; 2004
    In:  Human Brain Mapping Vol. 22, No. 2 ( 2004-06), p. 116-121
    Details
    In: Human Brain Mapping, Wiley, Vol. 22, No. 2 ( 2004-06), p. 116-121
    Kurzfassung: Previous studies have demonstrated the practicality of using functional magnetic resonance imaging (fMRI) techniques to assess fetal brain activity. The purpose of this study was to compare the fetal hemodynamic response to that of the adult. Seventeen pregnant subjects, all of whom were at more than 36 weeks gestation were scanned while the fetus was exposed to a vibroacoustic stimulus. Thirteen adult subjects were scanned with an equivalent acoustic stimulus. Of the fetal subjects, two could not be analyzed due to technical problems, eight did not show significant activation, and seven showed significant activation. In all cases, activation was localized within the temporal region. Measures of fetal hemodynamic responses revealed an average time to peak (ttp) of 7.36 ± 0.94 sec and an average percentage change of 2.67 ± 0.93%. In contrast, activation was detected in 5 of 13 adults with an average ttp of 6.54 ± 0.54 sec and an average percentage change of 1.02 ± 0.40%. The measurement of changes in the fetal hemodynamic response may be important in assessing compromised pregnancies. Hum. Brain Mapping 22:118–123, 2004. © 2004 Wiley‐Liss, Inc.
    Materialart: Online-Ressource
    ISSN: 1065-9471 , 1097-0193
    URL: Issue
    URL: Article
    DOI: 10.1002/hbm.v22:2
    DOI: 10.1002/hbm.20019
    Sprache: Englisch
    Verlag: Wiley
    Publikationsdatum: 2004
    ZDB Id: 1492703-2
    Standort Signatur Einschränkungen Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    Online-Ressource
  • 3
    Online-Ressource
    Online-Ressource
    Network analysis of nitrate-sensitive oral microbiome reveals interactions with cognitive function and cardiovascular health across dietary interventions
    Elsevier BV ; 2021
    In:  Redox Biology Vol. 41 ( 2021-05), p. 101933-
    Details
    In: Redox Biology, Elsevier BV, Vol. 41 ( 2021-05), p. 101933-
    Materialart: Online-Ressource
    ISSN: 2213-2317
    URL: Article
    DOI: 10.1016/j.redox.2021.101933
    Sprache: Englisch
    Verlag: Elsevier BV
    Publikationsdatum: 2021
    ZDB Id: 2701011-9
    Standort Signatur Einschränkungen Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    Online-Ressource
  • 4
    Online-Ressource
    Online-Ressource
    Muscle metabolism during fatiguing isometric quadriceps exercise in adolescents and adults
    Canadian Science Publishing ; 2014
    In:  Applied Physiology, Nutrition, and Metabolism Vol. 39, No. 4 ( 2014-04), p. 439-445
    Details
    In: Applied Physiology, Nutrition, and Metabolism, Canadian Science Publishing, Vol. 39, No. 4 ( 2014-04), p. 439-445
    Kurzfassung: Children and adolescents are less susceptible to muscle fatigue during repeated bouts of high-intensity exercise than adults, but the physiological basis for these differences is not clear. The purpose of the current investigation was to investigate the muscle metabolic responses, using 31-phosphorus magnetic resonance spectroscopy, during fatiguing isometric quadriceps exercise in 13 adolescents (7 females) and 14 adults (8 females). Participants completed 30 maximal voluntary contractions (6-s duration) separated by 6 s of rest. Fatigue was quantified as the relative decrease in force over the test. Fatigue was not significantly different with age (p = 0.20) or sex (p = 0.63). Metabolic perturbation (change in phosphocreatine, inorganic phosphate, and ADP concentrations) was significantly greater in adults compared with adolescents; no sex effects were present. Muscle pH did not differ with age or sex. Phosphocreatine recovery following exercise was not significantly different with age (p = 0.27) or sex (p = 0.97) but a significant interaction effect was present (p = 0.04). Recovery tended to be faster in boys than men but slower in girls than women, though no significant group differences were identified. The results of this study show that at a comparable level of muscle fatigue, the metabolic profile is profoundly different between adolescents and adults.
    Materialart: Online-Ressource
    ISSN: 1715-5312 , 1715-5320
    URL: Article
    DOI: 10.1139/apnm-2013-0192
    Sprache: Englisch
    Verlag: Canadian Science Publishing
    Publikationsdatum: 2014
    SSG: 31
    Standort Signatur Einschränkungen Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    Online-Ressource
  • 5
    Online-Ressource
    Online-Ressource
    The Impact of Disuse and High-Fat Overfeeding on Forearm Muscle Amino Acid Metabolism in Humans
    The Endocrine Society ; 2020
    In:  The Journal of Clinical Endocrinology & Metabolism Vol. 105, No. 7 ( 2020-07-01), p. e2547-e2562
    Details
    In: The Journal of Clinical Endocrinology & Metabolism, The Endocrine Society, Vol. 105, No. 7 ( 2020-07-01), p. e2547-e2562
    Kurzfassung: Anabolic resistance is mechanistically implicated in muscle disuse atrophy. Objective The objective of this study is to assess whether anabolic resistance is associated with reduced postprandial amino acid uptake or exacerbated by excess lipid availability. Design, Setting, Participants, and Interventions Twenty men underwent 7 days of forearm immobilization while consuming a eucaloric (CON; n = 11) or high-fat overfeeding (HFD; n = 9; 50% excess energy as fat) diet (parallel design) within our Nutritional Physiology Research Unit. Main Outcome Measures Preimmobilization and postimmobilization we measured forearm muscle cross-sectional area (aCSA), and postabsorptive and postprandial (3-hour postingestion of a liquid, protein-rich, mixed meal) forearm amino acid metabolism using the arterialized venous-deep venous balance method and infusions of L-[ring-2H5]phenylalanine and L-[1-13C] leucine. Results Immobilization did not affect forearm muscle aCSA in either group, but tended to reduce postabsorptive phenylalanine (P = .07) and leucine (P = .05) net balances equivalently in CON and HFD. Mixed-meal ingestion switched phenylalanine and leucine net balances from negative to positive (P & lt; .05), an effect blunted by immobilization (P & lt; .05) and to a greater extent in HFD than CON (P & lt; .05). Preimmobilization, meal ingestion increased leucine rates of disappearance (Rd; P & lt; .05), with values peaking at 191% (from 87 ± 38 to 254 ± 60 µmol·min–1·100 mL forearm volume–1) and 183% (from 141 ± 24 to 339 ± 51 µmol·min–1·100 mL–1) above postabsorptive rates in CON and HFD, respectively, with meal-induced increases not evident postimmobilization in either group (P & gt; .05). Conclusions Disuse impairs the ability of a protein-rich meal to promote positive muscle amino acid balance, which is aggravated by dietary lipid oversupply. Moreover, disuse reduced postprandial forearm amino acid uptake; however, this is not worsened under high-fat conditions.
    Materialart: Online-Ressource
    ISSN: 0021-972X , 1945-7197
    URL: Article
    DOI: 10.1210/clinem/dgaa184
    RVK:
    XA 10000
    Sprache: Englisch
    Verlag: The Endocrine Society
    Publikationsdatum: 2020
    ZDB Id: 2026217-6
    Standort Signatur Einschränkungen Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    Online-Ressource
  • 6
    Online-Ressource
    Online-Ressource
    Muscle damaging eccentric exercise attenuates disuse-induced declines in daily myofibrillar protein synthesis and transiently prevents muscle atrophy in healthy men
    American Physiological Society ; 2021
    In:  American Journal of Physiology-Endocrinology and Metabolism Vol. 321, No. 5 ( 2021-11-01), p. E674-E688
    Details
    In: American Journal of Physiology-Endocrinology and Metabolism, American Physiological Society, Vol. 321, No. 5 ( 2021-11-01), p. E674-E688
    Kurzfassung: Short-term disuse leads to muscle loss driven by lowered daily myofibrillar protein synthesis (MyoPS). However, disuse commonly results from muscle damage, and its influence on muscle deconditioning during disuse is unknown. Twenty-one males [20 ± 1 yr, BMI = 24 ± 1 kg·m −2 (± SE)] underwent 7 days of unilateral leg immobilization immediately preceded by 300 bilateral, maximal, muscle-damaging eccentric quadriceps contractions (DAM; subjects n = 10) or no exercise (CON; subjects n = 11). Participants ingested deuterated water and underwent temporal bilateral thigh MRI scans and vastus lateralis muscle biopsies of immobilized (IMM) and nonimmobilized (N-IMM) legs. N-IMM quadriceps muscle volume remained unchanged throughout both groups. IMM quadriceps muscle volume declined after 2 days by 1.7 ± 0.5% in CON ( P = 0.031; and by 1.3 ± 0.6% when corrected to N-IMM; P = 0.06) but did not change in DAM, and declined equivalently in CON [by 6.4 ± 1.1% (5.0 ± 1.6% when corrected to N-IMM)] and DAM [by 2.6 ± 1.8% (4.0 ± 1.9% when corrected to N-IMM)] after 7 days. Immobilization began to decrease MyoPS compared with N-IMM in both groups after 2 days ( P = 0.109), albeit with higher MyoPS rates in DAM compared with CON ( P = 0.035). Frank suppression of MyoPS was observed between days 2 and 7 in CON (IMM = 1.04 ± 0.12, N-IMM = 1.86 ± 0.10%·day −1 ; P = 0.002) but not DAM (IMM = 1.49 ± 0.29, N-IMM = 1.90 ± 0.30%·day −1 ; P 〉 0.05). Declines in MyoPS and quadriceps volume after 7 days correlated positively in CON ( r 2  = 0.403; P = 0.035) but negatively in DAM ( r 2  = 0.483; P = 0.037). Quadriceps strength declined following immobilization in both groups, but to a greater extent in DAM. Prior muscle-damaging eccentric exercise increases MyoPS and prevents loss of quadriceps muscle volume after 2 (but not 7) days of disuse. NEW & NOTEWORTHY We investigated the impact of prior muscle-damaging eccentric exercise on disuse-induced muscle deconditioning. Two and 7 days of muscle disuse per se lowered quadriceps muscle volume in association with lowered daily myofibrillar protein synthesis (MyoPS). Prior eccentric exercise prevented the decline in muscle volume after 2 days and attenuated the decline in MyoPS after 2 and 7 days. These data indicate eccentric exercise increases MyoPS and transiently prevents quadriceps muscle atrophy during muscle disuse.
    Materialart: Online-Ressource
    ISSN: 0193-1849 , 1522-1555
    URL: Article
    DOI: 10.1152/ajpendo.00294.2021
    Sprache: Englisch
    Verlag: American Physiological Society
    Publikationsdatum: 2021
    ZDB Id: 1477331-4
    SSG: 12
    Standort Signatur Einschränkungen Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    Online-Ressource
  • 7
    Online-Ressource
    Online-Ressource
    Muscle metabolic responses during high-intensity intermittent exercise measured by 31 P-MRS: relationship to the critical power concept
    American Physiological Society ; 2013
    In:  American Journal of Physiology-Regulatory, Integrative and Comparative Physiology Vol. 305, No. 9 ( 2013-11-01), p. R1085-R1092
    Details
    In: American Journal of Physiology-Regulatory, Integrative and Comparative Physiology, American Physiological Society, Vol. 305, No. 9 ( 2013-11-01), p. R1085-R1092
    Kurzfassung: We investigated the responses of intramuscular phosphate-linked metabolites and pH (as assessed by 31 P-MRS) during intermittent high-intensity exercise protocols performed with different recovery-interval durations. Following estimation of the parameters of the power-duration relationship, i.e., the critical power ( CP) and curvature constant ( W′), for severe-intensity constant-power exercise, nine male subjects completed three intermittent exercise protocols to exhaustion where periods of high-intensity constant-power exercise (60 s) were separated by different durations of passive recovery (18 s, 30 s and 48 s). The tolerable duration of exercise was 304 ± 68 s, 516 ± 142 s, and 847 ± 240 s for the 18-s, 30-s, and 48-s recovery protocols, respectively ( P 〈 0.05). The work done 〉 CP ( W 〉 CP ) was significantly greater for all intermittent protocols compared with the subjects' W′, and this difference became progressively greater as recovery-interval duration was increased. The restoration of intramuscular phosphocreatine concentration during recovery was greatest, intermediate, and least for 48 s, 30 s, and 18 s of recovery, respectively ( P 〈 0.05). The W 〉 CP in excess of W′ increased with greater durations of recovery, and this was correlated with the mean magnitude of muscle phosphocreatine reconstitution between work intervals ( r = 0.61; P 〈 0.01). The results of this study show that during intermittent high-intensity exercise, recovery intervals allow intramuscular homeostasis to be restored, with the degree of restoration being related to the duration of the recovery interval. Consequently, and consistent with the intermittent CP model, the ability to perform W 〉 CP during intermittent high-intensity exercise and, therefore, exercise tolerance, increases when recovery-interval duration is extended.
    Materialart: Online-Ressource
    ISSN: 0363-6119 , 1522-1490
    URL: Article
    DOI: 10.1152/ajpregu.00406.2013
    Sprache: Englisch
    Verlag: American Physiological Society
    Publikationsdatum: 2013
    ZDB Id: 1477297-8
    SSG: 12
    Standort Signatur Einschränkungen Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    Online-Ressource
  • 8
    Online-Ressource
    Online-Ressource
    Contralateral fatigue during severe-intensity single-leg exercise: influence of acute acetaminophen ingestion
    American Physiological Society ; 2019
    In:  American Journal of Physiology-Regulatory, Integrative and Comparative Physiology Vol. 317, No. 2 ( 2019-08-01), p. R346-R354
    Details
    In: American Journal of Physiology-Regulatory, Integrative and Comparative Physiology, American Physiological Society, Vol. 317, No. 2 ( 2019-08-01), p. R346-R354
    Kurzfassung: Exhaustive single-leg exercise has been suggested to reduce time to task failure (T lim ) during subsequent exercise in the contralateral leg by exacerbating central fatigue development. We investigated the influence of acetaminophen (ACT), an analgesic that may blunt central fatigue development, on T lim during single-leg exercise completed with and without prior fatiguing exercise of the contralateral leg. Fourteen recreationally active men performed single-leg severe-intensity knee-extensor exercise to T lim on the left (Leg 1 ) and right (Leg 2 ) legs without prior contralateral fatigue and on Leg 2 immediately following Leg 1 (Leg 2-CONTRA ). The tests were completed following ingestion of 1-g ACT or maltodextrin [placebo (PL)] capsules. Intramuscular phosphorus-containing metabolites and substrates and muscle activation were assessed using 31 P-MRS and electromyography, respectively. T lim was not different between Leg 1ACT and Leg 1PL conditions (402 ± 101 vs. 390 ± 106 s, P = 0.11). There was also no difference in T lim between Leg 2ACT-CONTRA and Leg 2PL-CONTRA (324 ± 85 vs. 311 ± 92 s, P = 0.10), but T lim was shorter in Leg 2ACT-CONTRA and Leg 2PL-CONTRA than in Leg 2CON (385 ± 104 s, both P 〈 0.05). There were no differences in intramuscular phosphorus-containing metabolites and substrates or muscle activation between Leg 1ACT and Leg 1PL and between Leg 2ACT-CONTRA and Leg 2PL-CONTRA (all P 〉 0.05). These findings suggest that levels of metabolic perturbation and muscle activation at T lim are not different during single-leg severe-intensity knee-extensor exercise completed with or without prior fatiguing exercise of the contralateral leg. Despite contralateral fatigue, ACT ingestion did not alter neuromuscular responses, muscle metabolites, or exercise performance.
    Materialart: Online-Ressource
    ISSN: 0363-6119 , 1522-1490
    URL: Article
    DOI: 10.1152/ajpregu.00084.2019
    Sprache: Englisch
    Verlag: American Physiological Society
    Publikationsdatum: 2019
    ZDB Id: 1477297-8
    SSG: 12
    Standort Signatur Einschränkungen Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    Online-Ressource
  • 9
    Online-Ressource
    Online-Ressource
    Muscle damage alters the metabolic response to dynamic exercise in humans: a 31 P-MRS study
    American Physiological Society ; 2011
    In:  Journal of Applied Physiology Vol. 111, No. 3 ( 2011-09), p. 782-790
    Details
    In: Journal of Applied Physiology, American Physiological Society, Vol. 111, No. 3 ( 2011-09), p. 782-790
    Kurzfassung: We used 31 P-magnetic resonance spectroscopy to test the hypothesis that exercise-induced muscle damage (EIMD) alters the muscle metabolic response to dynamic exercise, and that this contributes to the observed reduction in exercise tolerance following EIMD in humans. Ten healthy, physically active men performed incremental knee extensor exercise inside the bore of a whole body 1.5-T superconducting magnet before (pre) and 48 h after (post) performing 100 squats with a load corresponding to 70% of body mass. There were significant changes in all markers of muscle damage [perceived muscle soreness, creatine kinase activity (434% increase at 24 h), and isokinetic peak torque (16% decrease at 24 h)] following eccentric exercise. Muscle phosphocreatine concentration ([PCr] ) and pH values during incremental exercise were not different pre- and post-EIMD ( P 〉 0.05). However, resting inorganic phosphate concentration ([P i ]; pre: 4.7 ± 0.8; post: 6.7 ± 1.7 mM; P 〈 0.01) and, consequently, [P i ]/[PCr] values (pre: 0.12 ± 0.02; post: 0.18 ± 0.05; P 〈 0.01) were significantly elevated following EIMD. These mean differences were maintained during incremental exercise ( P 〈 0.05). Time to exhaustion was significantly reduced following EIMD (519 ± 56 and 459 ± 63 s, pre- and post-EIMD, respectively, P 〈 0.001). End-exercise pH (pre: 6.75 ± 0.04; post: 6.83 ± 0.04; P 〈 0.05) and [PCr] (pre: 7.2 ± 1.7; post: 14.5 ± 2.1 mM; P 〈 0.01) were higher, but end-exercise [P i ] was not significantly different (pre: 19.7 ± 1.9; post: 21.1 ± 2.6 mM, P 〉 0.05) following EIMD. The results indicate that alterations in phosphate metabolism, specifically the elevated [P i ] at rest and throughout exercise, may contribute to the reduced exercise tolerance observed following EIMD.
    Materialart: Online-Ressource
    ISSN: 8750-7587 , 1522-1601
    URL: Article
    DOI: 10.1152/japplphysiol.01021.2010
    RVK:
    WA 15000
    RVK:
    XA 52094
    Sprache: Englisch
    Verlag: American Physiological Society
    Publikationsdatum: 2011
    ZDB Id: 1404365-8
    SSG: 12
    SSG: 31
    Standort Signatur Einschränkungen Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    Online-Ressource
  • 10
    Online-Ressource
    Online-Ressource
    Influence of intermittent hypoxic training on muscle energetics and exercise tolerance
    American Physiological Society ; 2013
    In:  Journal of Applied Physiology Vol. 114, No. 5 ( 2013-03-01), p. 611-619
    Details
    In: Journal of Applied Physiology, American Physiological Society, Vol. 114, No. 5 ( 2013-03-01), p. 611-619
    Kurzfassung: Intermittent hypoxic training (IHT) is sometimes used by athletes to enhance nonhematological physiological adaptations to simulated altitude. We investigated whether IHT would result in greater improvements in muscle energetics and exercise tolerance compared with work-matched intermittent normoxic training (INT). Nine physically active men completed 3 wk of intensive, single-leg knee-extensor exercise training. Each training session consisted of 25 min of IHT (Fi O 2 14.5 ± 0.1%) with the experimental leg and 25 min of INT with the alternate leg, which served as a control. Before and after the training intervention, subjects completed a test protocol consisting of a bout of submaximal constant-work-rate exercise, a 24-s high-intensity exercise bout to quantify the phosphocreatine recovery time constant ([PCr]-τ), and an incremental test to the limit of tolerance. The tests were completed in normoxia and hypoxia in both INT and IHT legs. Muscle metabolism was assessed noninvasively using 31 P-magnetic resonance spectroscopy. Improvements in the time-to-exhaustion during incremental exercise were not significantly different between training conditions either in normoxia (INT, 28 ± 20% vs. IHT, 25 ± 9%; P = 0.86) or hypoxia (INT, 21 ± 10% vs. IHT, 15 ± 11%; P = 0.29). In hypoxia, [PCr]-τ was speeded slightly but significantly more post-IHT compared with post-INT (−7.3 ± 2.9 s vs. −3.7 ± 1.7 s; P 〈 0.01), but changes in muscle metabolite concentrations during exercise were essentially not different between IHT and INT. Under the conditions of this investigation, IHT does not appreciably alter muscle metabolic responses or incremental exercise performance compared with INT.
    Materialart: Online-Ressource
    ISSN: 8750-7587 , 1522-1601
    URL: Article
    DOI: 10.1152/japplphysiol.01331.2012
    RVK:
    WA 15000
    RVK:
    XA 52094
    Sprache: Englisch
    Verlag: American Physiological Society
    Publikationsdatum: 2013
    ZDB Id: 1404365-8
    SSG: 12
    SSG: 31
    Standort Signatur Einschränkungen Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    Online-Ressource
Schließen ⊗
Diese Webseite nutzt Cookies und das Analyse-Tool Matomo. Weitere Informationen finden Sie hier...