Description: This dataset comprises new data and previously published data on marine lipid biomarkers (brassicasterol, dinosterol, C37 alkenones, and the sum of them [∑PB]) in surface suspended particles at 334 stations from seven cruises between 2010 and 2015, and in surface sediments at 258 stations from eight cruises between 2006 and 2012 in the eastern China marginal seas (ECMS). Of all marine lipid biomarker data, 107 surface suspended particle samples were newly measured, with 227 surface suspended particle samples and 258 sediment samples previously published. We also provide the following oceanographic data, most of which were collected from published results (as described in the publication): sea surface temperature (SST, n = 273, from five cruises in summer of 2010–2015), salinity (n = 273, from five cruises in summer of 2010–2015), nutrient concentrations (dissolved inorganic nitrogen [DIN], dissolved inorganic phosphorus [DIP] and silicate [Si]) (n = 133, from three cruises in summer of 2011 and 2015) and Chl a (chlorophyll a, n = 229, from five cruises in summer of 2010–2014) in the surface water, as well as terrestrial biomarker [∑(C27 + C29 + C31) n-alkanes] contents (n = 226), TOC (total organic carbon content, n = 200), δ13CTOC (stable carbon isotope values for TOC, n=269), and sedimentation rate (n = 220) in surface sediments. Some data were measured using in situ CTD instrument in this study: sea surface temperature and salinity in the East China Sea in June 2010 and July 2013 (n = 54), and Chl a in the Changjiang River Estuary in August 2015 (n = 33). The contents of ∑(C27 + C29 + C31) n-alkanes in the southern Yellow Sea in April 2012 (n = 32) were also newly measured. The surface suspended particle samples were obtained by filtering on Whatman GF/F filters, and the surface sediments were collected by multiple corers or stainless-steel grab samplers. Marine and terrestrial lipid biomarkers were analyzed by gas chromatograph (Agilent 6890N) according to the method in Zhao et al. 2006 (doi: 10.1016/j.orggeochem.2005.08.022) and Wu et al. 2016 (doi: 10.1002/2015JG003167). The study resulting from this analysis has been published in Frontiers in Marine Science (doi:10.3389/fmars.2022.824181).

Description: Crystal Growth & Design DOI: 10.1021/acs.cgd.5b01559

Description: Background : HBsAg clearance represents a clinical cure although the clearance rate is extremely low. The aim of this study was to evaluate the feasibility and safety profiles of pegylated-interferon α-2a (PEG-IFNα-2a) as a therapeutic option for inactive HBsAg carriers (IHCs). Methods : 144 IHCs were enrolled and divided into a therapeutic group (102 subjects) and control group (42 subjects). PEG-IFNα-2a and PEG-IFNα-2a combined with Adefovir Dipivoxil (ADV) were used for treatment group subjects with hepatitis B virus (HBV) DNA 〈20 IU/mL and 20 IU/mL≤HBV DNA〈2000 IU/mL, respectively. Total therapy duration was no more than 96 weeks. HBsAg clearance and seroconversion rates at the therapeutic week 48 and 96 were used to evaluate the therapeutic efficacy. Results : Per-protocol (PP) analysis showed that HBsAg clearance rate and seroconversion rate in the treatment group were 29.8% and 20.2% at week 48, increased to 44.7% and 38.3% at week 96. However, the HBsAg clearance rate in control group was 2.4% at weeks 48 and 96, and no subject achieved seroconversion. The quantitative HBsAg levels and the changes during the early period of treatment (at week 12 and week 24), alanine transaminase (ALT) elevation at week 12 were strong predictors of HBsAg clearance. The adverse events were similar to the treatment for chronic hepatitis B patients. Conclusion : High rates of HBsAg clearance and seroconversion could achieve by PEG-IFN α-2a based treatments and the treatments were relatively safe for IHCs. This article is protected by copyright. All rights reserved.

Description: Microscopic vision measurement precision has been largely limited by inaccurately calibrated model parameters, because image plane is near parallel to reference plane in the narrow depth of field. This article proposes a method of precise microscopic vision measurement based on the adaptive positioning of the camera coordinate frame. The microscopic vision measurement movably attaches the origin of the camera coordinate frame along the optical axis. By finding the optimal position, the nonlinearity of the objective function in calibration optimization is decreased and the optimization sensitivity to initial values is reduced. Therefore, we obtain a high calibration precision and eventually ensure a high measurement precision. Mathematical simulations illustrate that the calibration precision of the proposed microscopic vision measurement model is higher than that of the conventional vision measurement model. The experiment shows that with magnification of 3.024×, the presented system achieves a precision of 0.12% based on the proposed microscopic vision measurement model, which is two times higher than the one based on the conventional vision measurement model. Microsc. Res. Tech. 2012. © 2012 Wiley Periodicals, Inc.