Note: Cover -- Half Title -- Title Page -- Copyright Page -- Preface -- Contents -- Contributors -- 1 Endotoxin: Historical Perspectives -- 2 Lipopolysaccharide and the Permeability of the Bacterial Outer Membrane -- 3 Lipopolysaccharide Phase Variation in Haemophilus and Neisseria -- 4 Antigenic Mimicry in Neisseria Species -- 5 Antibiotic-Induced Endotoxin Release: Important Parameters Dictating Responses -- 6 Complement-Mediated Lipopolysaccharide Release -- 7 Chemical Structure of Lipid A: Recent Advances in Structural Analysis of Biologically Active Molecules -- 8 Chemical Structure of the Core Region of Lipopolysaccharides -- 9 The Chemistry of O-Polysaccharide Chains in Bacterial Lipopolysaccharides -- 10 The Chemistry and Biology of Lipooligosaccharides: The Endotoxins of Bacteria of the Respiratory and Genital Mucosae -- 11 A Biophysical View on the Function and Activity of Endotoxins -- 12 Lipopolysaccharide Preparations in Aqueous Media: Implications for Solution Versus Suspension -- 13 Chlamydial Lipopolysaccharide -- 14 The Chemical Synthesis of Lipid A -- 15 Chemical Synthesis of Core Structures -- 16 Microbial Pathways of Lipid A Biosynthesis -- 17 Biosynthesis and Genetics of Lipopolysaccharide Core -- 18 Genetics and Biosynthesis of Lipopolysaccharide O-Antigens -- 19 Lipopolysaccharide-Binding Protein -- 20 Bactericidal/Permeability-Increasing Protein, p15s and Phospholipases A2, Endogenous Antibiotics in Host Defense Against Bacterial Infection -- 21 Interactions of Lipopolysaccharides and Lipoproteins -- 22 Effects of Human Hemoglobin on Bacterial Endotoxin In Vitro and In Vivo -- 23 LPS/Lipid A-Binding Synthetic Peptides -- 24 The Interaction of Lipid A and Lipopolysaccharide with Human Serum Albumin -- 25 Endothelial Cell Activation by Lipopolysaccharide: Role of Soluble CD14 -- 26 Scavenger Receptors and Lipopolysaccharide. , 27 The Role of Platelet-Activating Factor in Endotoxin-Related Disease -- 28 CD14, An Innate Immune Receptor for Various Bacterial Cell Wall Components -- 29 The Role of MAP Kinases, Phosphatidylinositol 3-Kinase, and Ceramide in LPS-Induced Signaling in Macrophages -- 30 Endotoxin Effects on Synthesis of Phosphatidic Acid and Phosphatidic Acid-Derived Diacylglyceride Species -- 31 Endotoxic Shock and the Sphingomyelin Pathway -- 32 Role of NF-κB in Macrophage Activation -- 33 Internalization of Lipopolysaccharide by Phagocytes -- 34 Multifunctional G Proteins: Implication in Endotoxin Cellular Responses -- 35 Immediate Cytokine Responses to Endotoxin: Tumor Necrosis Factor-α and the Interleukin-1 Family -- 36 Platelet-Activating Factor in Sepsis: An Update -- 37 Interleukin-10 and Other Suppressive Cytokines -- 38 Nitric Oxide as a Signaling Molecule in the Systemic Inflammatory Response to LPS -- 39 Studies of the Primate Inflammatory Hemostatic Axis and Its Response to Inflammatory Mediators -- 40 Biological Functions of Lipopolysaccharide Antibodies -- 41 Specificity and Neutralizing Properties of Cross-Reactive Anti-Core LPS Monoclonal Antibodies -- 42 Effects of Lipopolysaccharide on T Cells -- 43 Immunological Properties of Microbial Outer Membrane Proteins and Their Effects as Modulators of LPS Immunobiology -- 44 Opsonization of Actinobacillus actinomycetemcomitans by LPS-Directed IgG Antibodies in Sera of Juvenile Periodontitis Patients -- 45 Apoptotic Cell Death in Response to Lipopolysaccharide -- 46 Nontoxic RsDPLA As a Potent Antagonist of Toxic Lipopolysaccharide -- 47 Synthetic Endotoxin Antagonists -- 48 Bacteria-Induced Hypersensitivity to Endotoxin -- 49 Genetic Control of Endotoxin Responsiveness: The Lps Gene Revisited -- 50 Endotoxin Tolerance -- 51 Glucocorticoid Control of Endotoxin Responses. , 52 Gene Knockout Technology and the Host Response to Endotoxin: Role of CD14 and Other Inflammatory Mediators -- 53 Endotoxemia in Primate Models -- 54 The Value of Animal Models in Endotoxin Research -- 55 Pathophysiological Responses to Endotoxin in Humans -- 56 Endotoxin Detection in Body Fluids: Chemical Versus Bioassay Methodology -- 57 The Relevance of Endotoxin Detection in Sepsis -- 58 The Role of Gut-Derived Endotoxin in the Pathogenesis of Multiple Organ Dysfunction -- 59 Therapeutic Approaches Targeting Endotoxin-Derived Mediators -- 60 Human Responses to Endotoxin: Role of the Genetic Background -- 61 Endotoxin, Antibiotics, and Inflammation in Gram-Negative Infections -- 62 Lipopolysaccharide from Oral Bacteria: Role in Innate Host Defense and Chronic Inflammatory Disease -- 63 Endotoxin and Cancer -- 64 The Future of Endotoxin Research -- Index.

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