Note: Cover -- Title Page -- Copyright -- Contents -- Preface -- Chapter 1 Overview of Mammary Development -- Evolutionary Aspects -- Species Variation -- Fundamentals of Structure and Function -- Mammary Secretions and Milk -- Evaluation of Mammary Development -- Tissue, Cells, and Organization -- How to Quantify Mammary Development -- Gross Measures -- Biochemical Indices -- Histological Indices -- Technology Advances -- Cytology Indices -- Summary -- Structural Aspects of Mammary Development -- Fetal Development -- Structural Precursors of Mammary Glands -- Gland Number, Sexual Differentiation, and Species Variation -- Summary -- Birth to Conception -- Conception to Parturition -- Parenchymal and Stromal Tissue Development -- Appearance of Alveoli and Secretory Cells -- Mammary Cell Differentiation -- Lactating Mammary Gland -- Onset of Lactation to Mammary Involution -- The Lactation Curve -- Mammary Involution -- Unique Aspects of Involution in the Dairy Cow -- Chapter 2 Mammary Development, Anatomy, and Physiology -- Overview of Interactions-Focus on the Dairy Cow -- Blood Supply -- Angiogenesis -- Circulatory Route -- The Lymphatic System -- Significance of Blood Flow in Milk Production -- Nervous System -- Organizational Overview -- Autonomic Nervous System -- Milk Ejection and the Nervous System -- Endocrine System -- Classification of Endocrine Glands and Secretions -- Mechanisms of Hormone Action -- Chapter 3 Functional Developmentof the Mammary Gland -- Onset of Milk Secretion -- Lactogenesis -- Cellular Differentiation -- Cell-Cell Interactions -- Role of Milk Removal in Milk Secretion -- Milk Component Biosynthesis -- Structure and Function at the Secretory Cell Level -- Pathways for Protein and Lactose Secretion -- Pathways for Lipid Secretion -- Secretion of Other Milk Constituents -- Chapter 4 Milk Component Biosynthesis. , Metabolic Pathways and Precursors for Milk Biosynthesis -- Glycolysis, Gluconeogenesis, Krebs Cycle, and Energy Requirements -- Lactose Biosynthesis -- Milk Fat Biosynthesis -- Milk Protein Biosynthesis -- Biotechnologies and the Mammary Gland -- Chapter 5 Milking Management -- Physiological Factors and Machine Milking -- Teat Structure -- Teat Opening, Teat Canal, and Teat End -- Milking Machine Components -- Machine Milking and Mastitis Control -- Monitoring Udder Health -- Chapter 6 Endocrine, Growth Factor, and Neural Regulation of Mammary Development -- Steroid Hormones and Mammogenesis -- Steroids and Pregnancy -- Anterior Pituitary Hormones and Mammogenesis -- Other Hormones and Mammogenesis -- Local Tissue Mediators of Endocrine Action in Mammogenesis -- The Insulin-like Growth Factors Axis -- Epidermal Growth Factor Family -- Fibroblast Growth Factors -- Transforming Growth Factor -β -- Hepatocyte Growth Factor -- Parathyroid Hormone-Related Peptide -- Other Stroma-Derived Growth Regulators -- Chapter 7 Endocrine, Growth Factor, and Neural Regulation of Mammary Function -- Endocrine Regulation of Lactogenesis -- Periparturient Endocrine Profiles -- Essential Roles of Prl, Glucocorticoids, and Progesterone -- Endocrine Regulation of Galactopoiesis -- Hormone Secretion with Milking and Suckling -- Hormones and Galactopoiesis -- Prolactin -- Glucocorticoids -- Oxytocin -- Insulin -- Thyroid Hormones -- Somatotropin -- Somatotropin Effects on Milk Production -- Mode of Action for bST -- Effects on Udder Health -- Galactopoiesis and GH in Other Species -- Insulin-like Growth Factors and Galactopoiesis -- Pregnancy and Galactopoiesis -- Galactopoietic Effect of Milk Removal -- Other Aspects of Galactopoiesis -- Chapter 8 Biochemical Properties of Mammary Secretions -- Colostrum Formation -- Immunity Overview -- Antibody Structure and Function. , Antibody Transport and Receptors -- Colostrum Feeding and Management -- Milk Yield and Composition During Lactation -- Bioactive Milk Peptides, Growth Factors, and Hormones in Milk -- Hormones and Growth Factors in Milk -- Bioactive Peptides -- Chapter 9 Management and Nutritional Impacts on Mammary Development and Lactational Performance -- Interactions Between Metabolism and Intake -- Hormone and Metabolic Adjustments to Support Lactation -- Factors Controlling Voluntary Dry Matter Intake -- Role of the Hormone Leptin -- Other Hormones and VDMI in Ruminants -- Ketosis and Other Metabolic Disorders -- Parturient Hypocalcemia (Milk Fever) -- Acidosis and Laminitis -- Factors Affecting Milk Production -- Environmental Conditions -- Animal Factors Affecting Milk Production -- Role of Stress on Milk Production and Health -- Chapter 10 Manipulation of Mammary Development and Milk Production -- Photoperiod Effects on Dairy Cattle -- Effect of Dietary Manipulation on Mammary Development -- Effect of Growth Hormone on Mammary Development -- References -- Glossary -- Index.