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  • 1
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    Benzo[a]pyrene exposure under future ocean acidification scenarios weakens the immune responses of blood clam, Tegillarca granosa (2017)
    PANGAEA
    In:  Supplement to: Su, Wenhao; Zha, Shanjie; Wang, Yichen; Shi, Wei; Xiao, Guoqiang; Chai, Xueliang; Wu, Hongxi; Liu, Guangxu (2017): Benzo[a]pyrene exposure under future ocean acidification scenarios weakens the immune responses of blood clam, Tegillarca granosa. Fish & Shellfish Immunology, 63, 465-470, https://doi.org/10.1016/j.fsi.2017.02.046
    Details
    Publication Date: 2024-03-15
    Description: Persistent organic pollutants (POPs) are known to converge into the ocean and accumulate in the sediment, posing great threats to marine organisms such as the sessile bottom burrowing bivalves. However, the immune toxicity of POPs, such as B[a]P, under future ocean acidification scenarios remains poorly understood to date. Therefore, in the present study, the impacts of B[a]P exposure on the immune responses of a bivalve species, Tegillarca granosa, under present and future ocean acidification scenarios were investigated. Results obtained revealed an increased immune toxicity of B[a]P under future ocean acidification scenarios in terms of reduced THC, altered haemocyte composition, and hampered phagocytosis, which may attribute to the synergetic effects of B[a]P and ocean acidification. In addition, the gene expressions of pathogen pattern recognition receptors (TLR1, TLR2, TLR4, TLR6), pathway mediators (TRAF6, TAK1, TAB2, IKKalpha and Myd88), and effectors (NF-kB) of the important immune related pathways were significantly down-regulated upon exposure to B[a]P under future ocean acidification scenarios. Results of the present study suggested an increased immune toxicity of B[a]P under future ocean acidification scenarios, which will significantly hamper the immune responses of T. granosa and subsequently render individuals more susceptible to pathogens challenges.
    Keywords: Alkalinity, total; Alkalinity, total, standard deviation; Animalia; Aragonite saturation state; Aragonite saturation state, standard deviation; Benthic animals; Benthos; Bicarbonate ion; Brackish waters; Calcite saturation state; Calcite saturation state, standard deviation; Calculated using CO2SYS; Calculated using seacarb after Nisumaa et al. (2010); Carbon, inorganic, dissolved; Carbon, inorganic, dissolved, standard error; Carbonate ion; Carbonate system computation flag; Carbon dioxide; Containers and aquaria (20-1000 L or 〈 1 m**2); Date; Experiment duration; Figure; Fugacity of carbon dioxide (water) at sea surface temperature (wet air); Gene expression; Gene expression, standard error; Gene expression (incl. proteomics); Granulocyte, basophil; Granulocyte, basophil, standard error; Granulocyte, red; Granulocyte, red, standard error; Hemocyte count; Hemocyte count, standard error; Hyalinocyte; Hyalinocyte, standard error; Immunology/Self-protection; Laboratory experiment; Mass; Mass, standard error; Mollusca; North Pacific; OA-ICC; Ocean Acidification International Coordination Centre; Organic toxins; Partial pressure of carbon dioxide, standard deviation; Partial pressure of carbon dioxide (water) at sea surface temperature (wet air); pH; pH, standard deviation; Phagocytosis; Phagocytosis, standard error; Potentiometric; Potentiometric titration; Registration number of species; Salinity; Salinity, standard deviation; Single species; Species; Tegillarca granosa; Temperate; Temperature, water; Temperature, water, standard deviation; Tissues; Treatment; Type; Uniform resource locator/link to reference
    Type: Dataset
    Format: text/tab-separated-values, 1812 data points
    Location Call Number Limitation Availability
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    DATA PANGAEA
  • 2
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    Seawater carbonate chemistry and sperm-egg collisions, gamete fusion, and generation of Ca2+ oscillations of a broadcast spawning bivalve, Tegillarca granosa (2017)
    PANGAEA
    In:  Supplement to: Shi, Wei; Han, Yu; Guo, Cheng; Zhao, Xinguo; Liu, Saixi; Su, Wenhao; Wang, Yichen; Zha, Shanjie; Chai, Xueliang; Liu, Guangxu (2017): Ocean acidification hampers sperm-egg collisions, gamete fusion, and generation of Ca 2+ oscillations of a broadcast spawning bivalve, Tegillarca granosa. Marine Environmental Research, 130, 106-112, https://doi.org/10.1016/j.marenvres.2017.07.016
    Details
    Publication Date: 2024-03-15
    Description: Although the effect of ocean acidification on fertilization success of marine organisms is increasingly well documented, the underlying mechanisms are not completely understood. The fertilization success of broadcast spawning invertebrates depends on successful sperm-egg collisions, gamete fusion, and standard generation of Ca2+oscillations. Therefore, the realistic effects of future ocean pCO2 levels on these specific aspects of fertilization of Tegillarca granosa were investigated in the present study through sperm velocity trials, fertilization kinetics model analysis, and intracellular Ca2+assays, respectively. Results obtained indicated that ocean acidification significantly reduced the fertilization success of T. granosa, which could be accountable by (i) decreased sperm velocity hence reducing the probability for sperm-egg collisions; (ii) lowered probability of gamete fusion for each gamete collision event; and (iii) disrupted intracellular Ca2+ oscillations.
    Keywords: Alkalinity, total; Alkalinity, total, standard error; Amplitude; Animalia; Aragonite saturation state; Aragonite saturation state, standard error; Average path velocity; Average path velocity, standard error; Benthic animals; Benthos; Bicarbonate ion; Bottles or small containers/Aquaria (〈20 L); Calcite saturation state; Calcite saturation state, standard error; Calculated using CO2SYS; Calculated using seacarb after Nisumaa et al. (2010); Carbon, inorganic, dissolved; Carbon, inorganic, dissolved, standard error; Carbonate ion; Carbonate system computation flag; Carbon dioxide; Coast and continental shelf; Curvilinear velocity; Curvilinear velocity, standard error; EXP; Experiment; Fertilization success rate; Fluorescence intensity; Fugacity of carbon dioxide (water) at sea surface temperature (wet air); Laboratory experiment; Mollusca; North Pacific; OA-ICC; Ocean Acidification International Coordination Centre; Other metabolic rates; Partial pressure of carbon dioxide (water) at sea surface temperature (wet air); Partial pressure of carbon dioxide (water) at sea surface temperature (wet air), standard error; pH; pH, standard error; Potentiometric; Potentiometric titration; Probability; Registration number of species; Replicate; Reproduction; Salinity; Salinity, standard error; Single species; Species; Straight line velocity; Straight line velocity, standard error; Tegillarca granosa; Temperate; Temperature, water; Temperature, water, standard error; Treatment; Type; Uniform resource locator/link to reference; Yueqing_Bay
    Type: Dataset
    Format: text/tab-separated-values, 1080 data points
    Location Call Number Limitation Availability
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    DATA PANGAEA
  • 3
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    Seawater carbonate chemistry and cytoskeleton, lysozymes, and nitric oxide in hemocytes of blood clams, Tegillarca granosa. (2018)
    PANGAEA
    In:  Supplement to: Su, Wenhao; Rong, Jiahuan; Zha, Shanjie; Yan, Maocang; Fang, Jun; Liu, Guangxu (2018): Ocean Acidification Affects the Cytoskeleton, Lysozymes, and Nitric Oxide of Hemocytes: A Possible Explanation for the Hampered Phagocytosis in Blood Clams, Tegillarca granosa. Frontiers in Physiology, 9, https://doi.org/10.3389/fphys.2018.00619
    Details
    Publication Date: 2024-03-15
    Description: An enormous amount of anthropogenic carbon dioxide (CO2) has been dissolved into the ocean, leading to a lower pH and changes in the chemical properties of seawater, which has been termed ocean acidification (OA). The impacts of pCO2-driven acidification on immunity have been revealed recently in various marine organisms. However, the mechanism causing the reduction in phagocytosis still remains unclear. Therefore, the impacts of pCO2-driven OA at present and near-future levels (pH values of 8.1, 7.8, and 7.4) on the rate of phagocytosis, the abundance of cytoskeleton components, the levels of nitric oxide (NO), and the concentration and activity of lysozymes (LZM) of hemocytes were investigated in a commercial bivalve species, the blood clam (Tegillarca granosa). In addition, the effects of OA on the expression of genes regulating actin skeleton and nitric oxide synthesis 2 (NOS2) were also analyzed. The results obtained showed that the phagocytic rate, cytoskeleton component abundance, concentration and activity of LZM of hemocytes were all significantly reduced after a 2-week exposure to the future OA scenario of a pH of 7.4. On the contrary, a remarkable increase in the concentration of NO compared to that of the control was detected in clams exposed to OA. Furthermore, the expression of genes regulating the actin cytoskeleton and NOS were significantly up-regulated after OA exposure. Though the mechanism causing phagocytosis seemed to be complicated based on the results obtained in the present study and those reported previously, our results suggested that OA may reduce the phagocytosis of hemocytes by (1) decreasing the abundance of cytoskeleton components and therefore hampering the cytoskeleton-mediated process of engulfment, (2) reducing the concentration and activity of LZM and therefore constraining the degradation of the engulfed pathogen through an oxygen-independent pathway, and (3) inducing the production of NO, which may negatively regulate immune responses.
    Keywords: Alkalinity, total; Alkalinity, total, standard error; Animalia; Aragonite saturation state; Aragonite saturation state, standard error; Benthic animals; Benthos; Bicarbonate ion; Calcite saturation state; Calcite saturation state, standard error; Calculated using CO2SYS; Calculated using seacarb after Nisumaa et al. (2010); Carbon, inorganic, dissolved; Carbon, inorganic, dissolved, standard error; Carbonate ion; Carbonate system computation flag; Carbon dioxide; Coast and continental shelf; Containers and aquaria (20-1000 L or 〈 1 m**2); EXP; Experiment; Experiment duration; Fluorescence; Fugacity of carbon dioxide (water) at sea surface temperature (wet air); Gene expression, fold change, relative; Gene expression, fold change, relative, standard deviation; Gene expression (incl. proteomics); Gene name; Laboratory experiment; Lysozyme enzyme activity, per cell; Lysozyme in hemocytes, per cell; Mollusca; Nitric oxide in hemocytes, per cell; North Pacific; OA-ICC; Ocean Acidification International Coordination Centre; Other studied parameter or process; Partial pressure of carbon dioxide (water) at sea surface temperature (wet air); Partial pressure of carbon dioxide (water) at sea surface temperature (wet air), standard error; pH; pH, standard error; Phagocytosis rate; Potentiometric; Potentiometric titration; Qingjiang; Registration number of species; Replicate; Salinity; Salinity, standard error; Single species; Species; Tegillarca granosa; Temperate; Temperature, water; Temperature, water, standard error; Type; Uniform resource locator/link to reference
    Type: Dataset
    Format: text/tab-separated-values, 2781 data points
    Location Call Number Limitation Availability
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    DATA PANGAEA
  • 4
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    Seawater carbonate chemistry and foraging behavior of Acanthopagrus schlegelii (2018)
    PANGAEA
    In:  Supplement to: Rong, Jiahuan; Su, Wenhao; Guan, Xiaofan; Shi, Wei; Zha, Shanjie; He, Maolong; Wang, Haifeng; Liu, Guangxu (2018): Ocean Acidification Impairs Foraging Behavior by Interfering With Olfactory Neural Signal Transduction in Black Sea Bream, Acanthopagrus schlegelii. Frontiers in Physiology, 9, https://doi.org/10.3389/fphys.2018.01592
    Details
    Publication Date: 2024-03-15
    Description: In recent years, ocean acidification (OA) caused by oceanic absorption of anthropogenic carbon dioxide (CO2) has drawn worldwide concern over its physiological and ecological effects on marine organisms. However, the behavioral impacts of OA and especially the underlying physiological mechanisms causing these impacts are still poorly understood in marine species. Therefore, in the present study, the effects of elevated pCO2 on foraging behavior, in vivo contents of two important neurotransmitters, and the expression of genes encoding key modulatory enzymes from the olfactory transduction pathway were investigated in the larval black sea bream. The results showed that larval sea breams (length of 4.71 +- 0.45 cm) reared in pCO2 acidified seawater (pH at 7.8 and 7.4) for 15 days tend to stall longer at their acclimated zone and swim with a significant slower velocity in a more zigzag manner toward food source, thereby taking twice the amount of time than control (pH at 8.1) to reach the food source. These findings indicate that the foraging behavior of the sea bream was significantly impaired by ocean acidification. In addition, compared to a control, significant reductions in the in vivo contents of gama-aminobutyric acid (GABA) and Acetylcholine (ACh) were detected in ocean acidification-treated sea breams. Furthermore, in the acidified experiment groups, the expression of genes encoding positive regulators, the olfaction-specific G protein (Golf) and the G-protein signaling 2 (RGS2) and negative regulators, the G protein-coupled receptor kinase (GRK) and arrestin in the olfactory transduction pathway were found to be significantly suppressed and up-regulated, respectively. Changes in neurotransmitter content and expression of olfactory transduction related genes indicate a significant disruptive effect caused by OA on olfactory neural signal transduction, which might reveal the underlying cause of the hampered foraging behavior.
    Keywords: Acanthopagrus schlegelii; Acetylcholine; Alkalinity, total; Alkalinity, total, standard error; Animalia; Aragonite saturation state; Aragonite saturation state, standard error; Behaviour; Bicarbonate ion; Calcite saturation state; Calcite saturation state, standard error; Calculated using seacarb after Nisumaa et al. (2010); Carbon, inorganic, dissolved; Carbon, inorganic, dissolved, standard error; Carbonate ion; Carbonate system computation flag; Carbon dioxide; Chordata; Coast and continental shelf; Containers and aquaria (20-1000 L or 〈 1 m**2); Curvilinear velocity; Experiment duration; Fugacity of carbon dioxide (water) at sea surface temperature (wet air); gamma-Aminobutyric acid; Gene expression; Gene expression (incl. proteomics); Laboratory experiment; Latency time; Linearity index; Nekton; North Pacific; OA-ICC; Ocean Acidification International Coordination Centre; Partial pressure of carbon dioxide (water) at sea surface temperature (wet air); Partial pressure of carbon dioxide (water) at sea surface temperature (wet air), standard error; Pelagos; pH; pH, standard error; Registration number of species; Response time; Salinity; Salinity, standard error; Single species; Species; Temperate; Temperature, water; Temperature, water, standard error; Type; Uniform resource locator/link to reference; Wobble
    Type: Dataset
    Format: text/tab-separated-values, 4491 data points
    Location Call Number Limitation Availability
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    DATA PANGAEA
  • 5
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    Seawater carbonate chemistry and sperm motility and fertilisation success in blood clam, Tegillarca granosa (2017)
    PANGAEA
    In:  Supplement to: Shi, Wei; Zhao, Xinguo; Han, Yu; Guo, Cheng; Liu, Saixi; Su, Wenhao; Wang, Yichen; Zha, Shanjie; Chai, Xueliang; Fu, Wandong; Yang, Huicheng; Liu, Guangxu (2017): Effects of reduced pH and elevated pCO2 on sperm motility and fertilisation success in blood clam, Tegillarca granosa. New Zealand Journal of Marine and Freshwater Research, 51(4), 543-554, https://doi.org/10.1080/00288330.2017.1296006
    Details
    Publication Date: 2024-03-15
    Description: Although it has been shown that ocean acidification generally has a negative impact on fertilisation success of broadcast spawning marine organisms, whether induced fertilisation success reduction is a consequence of elevated pCO2 or decreased pH remains unclear. Therefore, the impacts of HCl- and CO2-induced acidified seawater on sperm motility and gametes fertilisation capability of a broadcast spawning bivalve species, Tegillarca granosa were investigated in the present study. The results showed that the fertilisation capability of both gametes was significantly reduced in either HCl- or CO2-acidified seawater. In addition, significant impacts on sperm motility were observed in the group exposed to CO2-acidified seawater, suggesting that this parameter is sensitive to pCO2 instead of solely pH value. The differences between the two seawater acidification manipulating methods may be due to the intrinsic difference in diffusion capability of CO2 and protons.
    Keywords: Alkalinity, total; Alkalinity, total, standard deviation; Animalia; Aragonite saturation state; Aragonite saturation state, standard deviation; Average path velocity; Average path velocity, standard deviation; Benthic animals; Benthos; Bicarbonate ion; Bottles or small containers/Aquaria (〈20 L); Calcite saturation state; Calcite saturation state, standard deviation; Calculated using CO2SYS; Calculated using seacarb after Nisumaa et al. (2010); Carbon, inorganic, dissolved; Carbon, inorganic, dissolved, standard deviation; Carbonate ion; Carbonate system computation flag; Carbon dioxide; Coast and continental shelf; Curvilinear velocity; Curvilinear velocity, standard deviation; Fertilization success rate; Figure; Fugacity of carbon dioxide (water) at sea surface temperature (wet air); Laboratory experiment; Linearity; Linearity, standard deviation; Mollusca; North Pacific; OA-ICC; Ocean Acidification International Coordination Centre; Partial pressure of carbon dioxide, standard deviation; Partial pressure of carbon dioxide (water) at sea surface temperature (wet air); pH; pH, standard deviation; Potentiometric; Potentiometric titration; Registration number of species; Reproduction; Salinity; Salinity, standard deviation; Single species; Species; Straightness; Straightness, standard deviation; Tegillarca granosa; Temperate; Temperature, water; Temperature, water, standard deviation; Treatment; Type; Uniform resource locator/link to reference; Wobble; Wobble, standard deviation
    Type: Dataset
    Format: text/tab-separated-values, 870 data points
    Location Call Number Limitation Availability
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    DATA PANGAEA
  • 6
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    Seawater carbonate chemistry and microbial community composition and host-pathogen interactions between the blood clam and Vibrio harveyi (2017)
    PANGAEA
    In:  Supplement to: Zha, Shanjie; Liu, Saixi; Su, Wenhao; Shi, Wei; Xiao, Guoqiang; Yan, Maocang; Liu, Guangxu (2017): Laboratory simulation reveals significant impacts of ocean acidification on microbial community composition and host-pathogen interactions between the blood clam and Vibrio harveyi. Fish & Shellfish Immunology, 71, 393-398, https://doi.org/10.1016/j.fsi.2017.10.034
    Details
    Publication Date: 2024-03-15
    Description: It has been suggested that climate change may promote the outbreaks of diseases in the sea through altering the host susceptibility, the pathogen virulence, and the host-pathogen interaction. However, the impacts of ocean acidification (OA) on the pathogen components of bacterial community and the host-pathogen interaction of marine bivalves are still poorly understood. Therefore, 16S rRNA high-throughput sequencing and host-pathogen interaction analysis between blood clam (Tegillarca granosa) and Vibrio harveyi were conducted in the present study to gain a better understanding of the ecological impacts of ocean acidification. The results obtained revealed a significant impact of ocean acidification on the composition of microbial community at laboratory scale. Notably, the abundance of Vibrio, a major group of pathogens to many marine organisms, was significantly increased under ocean acidification condition. In addition, the survival rate and haemolytic activity of V. harveyi were significantly higher in the presence of haemolymph of OA treated T. granosa, indicating a compromised immunity of the clam and enhanced virulence of V. harveyi under future ocean acidification scenarios. Conclusively, the results obtained in this study suggest that future ocean acidification may increase the risk of Vibrio pathogen infection for marine bivalve species, such as blood clams.
    Keywords: Abundance; Alkalinity, total; Alkalinity, total, standard error; Animalia; Aragonite saturation state; Aragonite saturation state, standard error; Bacteria; Bacteria, abundance in colony forming units; Benthic animals; Benthos; Bicarbonate ion; Biomass/Abundance/Elemental composition; Calcite saturation state; Calcite saturation state, standard error; Calculated using CO2SYS; Calculated using seacarb after Nisumaa et al. (2010); Carbon, inorganic, dissolved; Carbonate ion; Carbonate system computation flag; Carbon dioxide; Coast and continental shelf; Community composition and diversity; Containers and aquaria (20-1000 L or 〈 1 m**2); Entire community; Experiment duration; Figure; Fugacity of carbon dioxide (water) at sea surface temperature (wet air); Group; Heterotrophic prokaryotes; Laboratory experiment; Mollusca; Mortality/Survival; North Pacific; OA-ICC; Ocean Acidification International Coordination Centre; Partial pressure of carbon dioxide (water) at sea surface temperature (wet air); Partial pressure of carbon dioxide (water) at sea surface temperature (wet air), standard error; Pelagos; pH; pH, standard error; Potentiometric; Potentiometric titration; Proteobacteria; Registration number of species; Replicate; Salinity; Salinity, standard error; Species; Species interaction; Survival; Temperate; Temperature, water; Temperature, water, standard error; Treatment; Type; Uniform resource locator/link to reference; Vibrio harveyi
    Type: Dataset
    Format: text/tab-separated-values, 7517 data points
    Location Call Number Limitation Availability
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    DATA PANGAEA
  • 7
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    Seawater carbonate chemistry and gustation mediated-feeding behavior of black sea bream, Acanthopagrus schlegelii (2020)
    PANGAEA
    Details
    Publication Date: 2024-03-15
    Description: Growing evidence suggests that ocean acidification (OA) may affect animal behaviors such as feeding. Although gustation plays a crucial role in evaluating the quality and palatability of food and ultimately influences whether or not teleosts consume the food, the potential impact of OA on gustation-mediated feeding behavior remains unknown. In this study, gustation mediated-feeding behavior, as indicated by the consumption rate (CR) and swallowing rate (SR) of agar pellets with or without feed upon OA exposure was investigated in black sea bream (Acanthopagrus schlegelii). Results showed that the exposure to acidified seawater led to significant reductions in the CR and SR of feed-containing agar pellets. In addition, the in vivo contents of three neurotransmitters and expression of genes from the gustatory signal transduction pathway were all significantly suppressed by the OA treatment. In general, the data obtained indicated that OA may hinder the gustation-mediated feeding behavior of A. schlegelii by disrupting gustatory signal transduction, which may aggravate the issue of food shortage for wild populations of black sea bream.
    Keywords: 5-hydroxytryptamine; Acanthopagrus schlegelii; Acetylcholine; Alkalinity, total; Alkalinity, total, standard error; Animalia; Aragonite saturation state; Aragonite saturation state, standard error; Behaviour; Benthic animals; Benthos; Bicarbonate ion; Calcite saturation state; Calcite saturation state, standard error; Calculated using CO2SYS; Calculated using seacarb after Nisumaa et al. (2010); Carbon, inorganic, dissolved; Carbon, inorganic, dissolved, standard error; Carbonate ion; Carbonate system computation flag; Carbon dioxide; Chordata; Coast and continental shelf; Consumption; Consumption, standard error; Containers and aquaria (20-1000 L or 〈 1 m**2); Experiment duration; Fugacity of carbon dioxide (water) at sea surface temperature (wet air); gamma-Aminobutyric acid; Gene expression, fold change, relative; Gene expression (incl. proteomics); Laboratory experiment; North Pacific; OA-ICC; Ocean Acidification International Coordination Centre; Other studied parameter or process; Partial pressure of carbon dioxide (water) at sea surface temperature (wet air); Partial pressure of carbon dioxide (water) at sea surface temperature (wet air), standard error; pH; pH, standard error; Potentiometric; Potentiometric titration; Registration number of species; Salinity; Salinity, standard error; Single species; Species; Swallowing rate; Swallowing rate, standard error; Temperate; Temperature, water; Temperature, water, standard error; Treatment; Type; Uniform resource locator/link to reference
    Type: Dataset
    Format: text/tab-separated-values, 2028 data points
    Location Call Number Limitation Availability
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    DATA PANGAEA
  • 8
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    Seawater carbonate chemistry and titanium dioxide nanoparticles (nTiO2) in edible bivalve mollusks (2019)
    PANGAEA
    In:  Supplement to: Shi, Wei; Han, Yu; Guo, Cheng; Su, Wenhao; Zhao, Xinguo; Zha, Shanjie; Wang, Yichen; Liu, Guangxu (2019): Ocean acidification increases the accumulation of titanium dioxide nanoparticles (nTiO2) in edible bivalve mollusks and poses a potential threat to seafood safety. Scientific Reports, 9(1), https://doi.org/10.1038/s41598-019-40047-1
    Details
    Publication Date: 2024-05-24
    Description: Large amounts of anthropogenic CO2 in the atmosphere are taken up by the ocean, which leads to 'ocean acidification' (OA). In addition, the increasing application of nanoparticles inevitably leads to their increased release into the aquatic environment. However, the impact of OA on the bioaccumulation of nanoparticles in marine organisms still remains unknown. This study investigated the effects of OA on the bioaccumulation of a model nanoparticle, titanium dioxide nanoparticles (nTiO2), in three edible bivalves. All species tested accumulated significantly greater amount of nTiO2 in pCO2-acidified seawater. Furthermore, the potential health threats of realistic nTiO2 quantities accumulated in bivalves under future OA scenarios were evaluated with a mouse assay, which revealed evident organ edema and alterations in hematologic indices and blood chemistry values under future OA scenario (pH at 7.4). Overall, this study suggests that OA would enhance the accumulation of nTiO2 in edible bivalves and may therefore increase the health risk for seafood consumers.
    Keywords: Alanine transaminase; Alanine transaminase, standard error; Alanine transaminase/Aspartate transaminase; Alanine transaminase/Aspartate transaminase, standard error; Alkaline phosphatase; Alkaline phosphatase, standard error; Alkalinity, total; Alkalinity, total, standard error; Animalia; Aragonite saturation state; Aragonite saturation state, standard error; Aspartate transaminase; Aspartate transaminase, standard error; Benthic animals; Benthos; Bicarbonate ion; Blood urea nitrogen; Blood urea nitrogen, standard error; Calcite saturation state; Calcite saturation state, standard error; Calculated using seacarb after Nisumaa et al. (2010); Carbon, inorganic, dissolved; Carbon, inorganic, dissolved, standard error; Carbonate ion; Carbonate system computation flag; Carbon dioxide; Coast and continental shelf; Containers and aquaria (20-1000 L or 〈 1 m**2); Creatinine; Creatinine, standard error; Cyclina sinensis; Fugacity of carbon dioxide (water) at sea surface temperature (wet air); Granulocytes; Granulocytes, standard error; Haemoglobin; Haemoglobin, standard error; Inorganic toxins; Laboratory experiment; Lymphocytes, standard error; Lymphocytes in blood; Mean corpuscular haemoglobin; Mean corpuscular haemoglobin, standard error; Mean corpuscular haemoglobin concentration; Mean corpuscular haemoglobin concentration, standard error; Mean corpuscular volume; Mean corpuscular volume, standard error; Meretrix meretrix; Mollusca; Monocytes, standard error; Monocytes in blood; North Pacific; OA-ICC; Ocean Acidification International Coordination Centre; Other metabolic rates; Packed cell volume (haematocrit); Packed cell volume (haematocrit), standard error; Partial pressure of carbon dioxide (water) at sea surface temperature (wet air); Partial pressure of carbon dioxide (water) at sea surface temperature (wet air), standard error; pH; pH, standard error; Red blood cells; Red blood cells, standard error; Red cell distribution width; Red cell distribution width, standard error; Registration number of species; Salinity; Salinity, standard error; Single species; Species; Tegillarca granosa; Temperate; Temperature, water; Temperature, water, standard error; Tissues; Titanium dioxide, in tissue, per dry mass; Titanium dioxide, standard error; Type; Uniform resource locator/link to reference; White blood cell; White blood cell, standard error
    Type: Dataset
    Format: text/tab-separated-values, 1125 data points
    Location Call Number Limitation Availability
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    DATA PANGAEA
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