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  • 1
    ISSN: 1573-7284
    Keywords: Foodborne-outbreak ; Powdered infant formula ; Salmonella virchow lactose +
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Spain's Salmonella surveillance system backed by regionally-based epidemiologists around the country made it possible to detect and halt the spread of a foodborne salmonellosis outbreak due to powdered infant formula contaminated with a lactose-fermenting strain of Salmonella virchow. Forty-eight cases involving children, mostly under 7 months old, were detected in 14 out of Spain's 17 Regions. The outbreak started in January and ended in June 1994. All cases were microbiologically confirmed. The implicated strain had a 3.6 kb plasmid, was susceptible to all antimicrobials tested except nitrofurantoin and was phagetype 4a. Isolates from 8 of 24 Brand “A” milk samples tested had the same characteristics as case isolates. All affected/suspect batches of Brand “A” milk were destroyed and the product withdrawn from sale, which led to the end of the outbreak. This incident underscores the importance of maintaining surveillance systems able to detect and prevent foodborne outbreaks and alert to the possibility of isolating unusual lactose-fermenting Salmonella serotypes in especially sensitive food products.
    Type of Medium: Electronic Resource
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  • 2
    Publication Date: 2017-01-18
    Description: Recently acquired swath-bathymetry data and high-resolution seismic reflection profiles offshore Adra (Almería, Spain) reveal the surficial expression of a NW–SE trending 20 km-long fault, which we termed the Adra Fault. Seismic imaging across the structure depicts a sub-vertical fault reaching the seafloor surface and slightly dipping to the NE showing an along-axis structural variability. Our new data suggest normal displacement of the uppermost units with probably a lateral component. Radiocarbon dating of a gravity core located in the area indicates that seafloor sediments are of Holocene age, suggesting present-day tectonic activity. The NE Alboran Sea area is characterized by significant low-magnitude earthquakes and by historical records of moderate magnitude, such as the Mw = 6.1 1910 Adra Earthquake. The location, dimension and kinematics of the Adra Fault agree with the fault solution and magnitude of the 1910 Adra Earthquake, whose moment tensor analysis indicates normal-dextral motion. The fault seismic parameters indicate that the Adra Fault is a potential source of large magnitude (Mw ≤ 6.5) earthquakes, which represents an unreported seismic hazard for the neighbouring coastal areas.
    Type: Article , PeerReviewed
    Format: text
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  • 3
    Publication Date: 2021-05-11
    Description: Eight consecutive swath bathymetry data sets were obtained to monitor the submarine eruption that occurred from 10 October 2011 to 5 March 2012 south of El Hierro Island in the Canary Islands. An increase in seismic activity since July 2011 preceded the onset of the eruption, which was marked by seismic tremor and stained waters. The first bathymetry, 15 d after the eruption started, depicts a cone topping at 205 m depth, growing on a preexisting valley. Recurrent mapping shows changes in the morphology and depth of the cone, allowing us to identify collapses and calculate eruptive volumes and rates, which peaked at 12.7 × 106 m3 d−1 of non–dense rock equivalent (NDRE) on 29–30 October. The final cone consists of at least four vents along a north-northwest–south-southeast lineation, with the shallowest summit at 89 m depth. The total accumulated volume was 329 × 106 NDRE m3, of which one-third formed the cone. Similar cones have been identified on the submerged flanks of the island, with volumes ranging from 〈50 × 106 to 〉1000 × 106 NDRE m3. As in many other volcanic islands, large-scale landslides play an important role in the evolution of El Hierro. A giant flank landslide (El Golfo, 13–134 ka, 150–180 km3) mobilized, in a single event, a volume equivalent to 450–550 eruptions of the size of the reported one, showing striking differences in the construction and destruction rates of the island. This study is relevant for future monitoring programs and geohazard assessment of new submarine eruptions.
    Type: Article , PeerReviewed
    Format: text
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  • 4
    Publication Date: 2018-05-31
    Description: Recent advances in seafloor and subsurface imaging allow accurately mapping and characterizing the kinematic pattern and the style of deformation of submarine faults with unprecedented detail to better assess seismic and tsunami hazards in coastal areas. The Alboran Sea is a Neogene basin generated by crustal extension associated with the subduction in the Gibraltar Arc. At present, several fault systems absorb part of the strain related to the NW-SE convergence (4-5.5 mm/yr) between the African and Eurasian plates. Consequently, the Alboran Sea shows a significant seismic activity. New high-resolution bathymetric and seismic data reveal the presence of poorly known pervasive fault systems in the central part of the Alboran Sea, the Averroes Fault (AF) and the North Averroes Faults (NAFs). These are secondary fault systems located between two large active faults, the Carboneras and Yusuf/Alboran Ridge faults, and represent a hitherto unrecognized seismogenic potential. The WNW-ESE trending AF and NAFs, which may have evolved since the Lower Pliocene (4.57 Ma), are subvertical right-lateral strike-slip active faults since: a) are offsetting the Quaternary sedimentary units and deforming the seafloor; and b) produce a right-lateral displacement of the northwestern margin of the Alboran Channel and across the Adra Ridge North. Given that the AF and NAFs have formed in a continental crust and that are located in a zone surrounded by some of the main active faults in the Alboran Sea, we postulate that these fault systems have been developed into a distributed dextral strike-slip shear zone with the local bulk shear striking approximately N90º. Considering their surface length they could generate earthquakes with magnitudes (Mw) between 6.3 and 7.2, but reaching 7.6 when AF and Yusuf Fault are linked. The high resolution bathymetry map has allowed us measuring lateral offsets produced by the AF and NAFs. Assuming that these displacements have been accumulated during the last 4.57 Ma, the calculated lateral slip rate for AF is approximately1.5 mm/yr and range between 0.2 and 0.4 mm/yr for the NAFs. Our results evidence the importance of the kinematic and seismogenic characterization of secondary fault systems to better comprehend earthquake and tsunami hazards.
    Type: Conference or Workshop Item , NonPeerReviewed
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  • 5
    Publication Date: 2017-12-14
    Description: Aim Accumulated evidence suggests that aberrant methylation of the TP73 gene and increased levels of Np73 in primary tumours correlate with poor prognosis. However, little is known regarding the transcriptional and functional regulation of the TP73 gene in breast cancer. The aim of the present study was to determine the expression of the Np73 isoform, its relationship with DNA methylation of TP73 and their clinical prognostic significance in breast cancer patients. Methods TP73 gene methylation was studied in TCGA datasets and in 70 invasive ductal breast carcinomas (IDCs). The expression of p73 isoforms was evaluated by immunohistochemistry (IHC) and Western blot and correlated with clinicopathological variables and clinical outcome. Results We observed that the methylation of diverse CpG islands of TP73 differed significantly between molecular subtypes. An inverse correlation was found between p73 protein expression and the methylation status of the TP73 gene. The expression of exon 3’ of p73 (only expressed in Np73) was significantly higher in patients with wild-type p53. Immunohistochemical analysis revealed that all p73 isoforms were localised in both the nuclear and cytoplasmic compartments. We confirmed a positive association between the expression of Np73 and high histological grade. Conclusions Our findings suggest that high expression of Np73 could be used to determine the aggressiveness of IDCs and could be incorporated in the pathologist’s report.
    Keywords: Diagnostics
    Print ISSN: 0021-9746
    Electronic ISSN: 1472-4146
    Topics: Medicine
    Published by BMJ Publishing Group
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  • 6
    Publication Date: 2013-02-20
    Description: Eight consecutive swath bathymetry data sets were obtained to monitor the submarine eruption that occurred from 10 October 2011 to 5 March 2012 south of El Hierro Island in the Canary Islands. An increase in seismic activity since July 2011 preceded the onset of the eruption, which was marked by seismic tremor and stained waters. The first bathymetry, 15 d after the eruption started, depicts a cone topping at 205 m depth, growing on a preexisting valley. Recurrent mapping shows changes in the morphology and depth of the cone, allowing us to identify collapses and calculate eruptive volumes and rates, which peaked at 12.7 x 10 6 m 3 d –1 of non–dense rock equivalent (NDRE) on 29–30 October. The final cone consists of at least four vents along a north-northwest–south-southeast lineation, with the shallowest summit at 89 m depth. The total accumulated volume was 329 x 10 6 NDRE m 3 , of which one-third formed the cone. Similar cones have been identified on the submerged flanks of the island, with volumes ranging from 〈50 x 10 6 to 〉1000 x 10 6 NDRE m 3 . As in many other volcanic islands, large-scale landslides play an important role in the evolution of El Hierro. A giant flank landslide (El Golfo, 13–134 ka, 150–180 km 3 ) mobilized, in a single event, a volume equivalent to 450–550 eruptions of the size of the reported one, showing striking differences in the construction and destruction rates of the island. This study is relevant for future monitoring programs and geohazard assessment of new submarine eruptions.
    Print ISSN: 0091-7613
    Electronic ISSN: 1943-2682
    Topics: Geosciences
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  • 7
    Publication Date: 2021-05-19
    Description: Resalta la importancia de la imprenta en la historia de la humanidad, ademas de explicar la utilidad que tiene actualmente para la elaboración de cartas náuticas en la Dirección de Hidrografia y Navegación.
    Description: Published
    Description: Impresion de cartas nauticas
    Keywords: Imprinting
    Repository Name: AquaDocs
    Type: Theses and Dissertations , Bachelor thesis
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