GLORIA

GEOMAR Library Ocean Research Information Access

feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
  • 1
    facet.materialart.
    Unknown
    PANGAEA
    In:  Supplement to: Murphy, Conor; Broderick, Ciaran; Burt, Timothy P; Curley, Mary; Duffy, Catriona; Hall, Julia; Harrigan, Shaun; Matthews, Tom K R; Macdonald, Neil; McCarthy, Gerard D; McCarthy, Mark P; Mullan, Donal; Noone, Simon; Osborn, Timothy J; Ryan, Ciara; Sweeney, John; Thorne, Peter W; Walsh, Seamus; Wilby, Robert L (2017): A 305-year continuous monthly rainfall series for the Island of Ireland (1711-2016). Climate of the Past Discussions, 14(1), 1-39, https://doi.org/10.5194/cp-2017-142
    Publication Date: 2024-06-18
    Description: This dataset provides a continuous monthly rainfall series for the Island of Ireland commencing in January 1711 and running to December 2016. It draws upon diverse sources including weather diaries and early observations. The early record has been quality assured (so far as is possible), through comparison with other long term observational records and climate reconstructions for the regions of the British Irish Isles.
    Keywords: DATE/TIME; Ireland; Is_of_Ireland; Precipitation, monthly total
    Type: Dataset
    Format: text/tab-separated-values, 3672 data points
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
  • 2
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Annals of the New York Academy of Sciences 804 (1996), S. 0 
    ISSN: 1749-6632
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Natural Sciences in General
    Type of Medium: Electronic Resource
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Journal of cancer research and clinical oncology 119 (1993), S. 504-505 
    ISSN: 1432-1335
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
  • 4
    ISSN: 1432-0738
    Keywords: Key words Apoptosis ; Diethylhexylphthalate (DEHP) ; Diisononylphthalate (DINP) ; DNA synthesis ; Peroxisome proliferation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Diethylhexylphthalate (DEHP) and diisononylphthalate (DINP) are plasticizers with many important commercial, industrial and medical applications. However, both DEHP and DINP are rodent peroxisome proliferators (PPs), a class of compounds that cause rodent liver tumours associated with peroxisome proliferation, induction of hepatic DNA synthesis and the suppression of apoptosis. Despite these effects in the rodent, humans appear to be nonresponsive to the adverse effects of PPs. Previously, we have shown that the fibrate hypolipidaemic peroxisome proliferator, nafenopin, induced DNA synthesis and suppressed apoptosis in rat but not in human hepatocytes. In this work, we have examined species differences in the response of rat and human hepatocytes to DEHP and DINP in vitro. In rat hepatocytes in vitro, both DINP and MEHP (a principle metabolite of DEHP and the proximal peroxisome proliferator) caused a concentration-dependent induction of DNA synthesis and suppression of both spontaneous and transforming growth factor β1 (TGFβ1)-induced apoptosis. Similarly, both MEHP and DINP caused a concentration-dependent induction of peroxisomal β-oxidation although the response to DINP was less robust. In contrast to the pleiotropic response noted in rat hepatocytes, neither DINP nor MEHP caused an induction of β-oxidation, stimulation of DNA synthesis and suppression of apoptosis in human hepatocytes cultured from three separate donors. These data provide evidence for species differences in the hepatic response to the phthalates DEHP and DINP, confirming that human hepatocytes appear to be refractory to the hepatocarcinogenic effects of PPs first noted in rodents.
    Type of Medium: Electronic Resource
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
  • 5
    ISSN: 1432-0738
    Keywords: Key words Diethylhexylphthalate ; Peroxisome proliferation ; Hepatocarcinogenesis ; Species differences ; Human
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Diethylhexylphthalate (DEHP) is a phthalate plasticizer that belongs to the peroxisome proliferator (PP) class of rodent nongenotoxic hepatocarcinogens. Previously, we have shown that MEHP (a principal metabolite of DEHP and the proximal PP) induced DNA synthesis and suppressed apoptosis in rat but not in human hepatocytes in vitro. Here, we present further studies of species differences in response to DEHP. In rats, 4 days of exposure to DEHP (950 mg/kg per day by gavage) induced peroxisomal β-oxidation, DNA synthesis and suppressed apoptosis. In contrast, there was no response of guinea pig liver to DEHP. In rat hepatocytes in vitro, MEHP (250, 500 and 750 μM) induced peroxisomal β-oxidation, DNA synthesis and suppressed apoptosis. In contrast to the pleiotropic response noted in rat hepatocytes, there was no response of human hepatocytes to 250, 500 or 750 μM MEHP. PPs activate the peroxisome proliferator activated receptor alpha (PPARα) that binds to DNA at peroxisome proliferator response elements (PPREs) within the promoters of PP-responsive genes such as rat acyl CoA oxidase (ACO). However, the human ACO gene promoter differs at three bases within the PPRE from the rat ACO promoter and appears refractory to PPs. To address species differences in response to DEHP at the molecular level, we used promoter-reporter gene assays to compare the ability of MEHP to induce gene expression from the rat or the human ACO promoter. MEHP gave a concentration-dependent increase in reporter gene expression from the rat ACO gene promoter with either mouse or human PPARα. In contrast, the human ACO promoter was unable to drive MEHP-induced gene transcription irrespective of the species origin of PPARα. These data provide further weight of evidence at the cellular and molecular levels for a lack of risk to human health from the phthalate DEHP.
    Type of Medium: Electronic Resource
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
  • 6
    Electronic Resource
    Electronic Resource
    Springer
    Soil Science Society of America journal 63 (1999), S. 211-218 
    ISSN: 1435-0661
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences , Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes: 2 -C respired and dissolved organic C leached from the soil cores during a 33-wk period. Microbial respiration rates, after adjustment for variation in initial rates, were significantly increased by soil warming and were greater in surface that in subsurface horizons. Warming significantly increased cumulative C respired, with greater losses from surface soils (≥50 mg C g-1 C) as compared with subsurface soils (≤25 mg C g-1 C). Mean quantities of dissolved organic C leached, ranging from 2.3 to 3.2 mg C g-1 C, did not differ significantly by soil horizon or temperature regime. Increased microbial respiration in surface soil horizons was the process most responsive to soil warming in the Spodosol samples we examined. Whether this is a short-term effect that would disappear once pools of labile C are exhausted, or represents a long-term response to soil warming, remains uncertain.
    Type of Medium: Electronic Resource
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
  • 7
    ISSN: 1435-0661
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences , Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes: 2 and inorganic N. First-order kinetic models described the accumulation of CO2 and inorganic N and accounted for 96 to 99% of the variation in these processes. First-order rate constants (k) for net N mineralization significantly increased with temperature, but the k for microbial respiration did not increase in a consistent manner; it was 0.107 wk-1 at 5°C, 0.123 wk-1 at 10°C, and 0.101 wk-1 at 25° C. Matric potential did not significantly influence k for either process. Substrate pools for microbial respiration and net N mineralization declined between -0.01 and -0.30 Mpa, and the decline was greatest at the highest soil temperature; this response produced a significant temperature-matric potential interaction. We conclude that high rates of microbial activity at warm soil temperatures (e.g., 25°C) are limited by the diffusion of substrate to metabolically active cells. This limitation apparently lessens as physiological activity and substrate demand decline at relatively cooler soil temperature (e.g., 5°C).
    Type of Medium: Electronic Resource
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
  • 8
    Publication Date: 2019-09-23
    Description: River flooding is among the most destructive of natural hazards globally, causing widespread loss of life, damage to infrastructure and economic deprivation. Societies are currently under increasing threat from such floods, predominantly from increasing exposure of people and assets in flood‐prone areas, but also as a result of changes in flood magnitude, frequency, and timing. Accurate flood hazard and risk assessment are therefore crucial for the sustainable development of societies worldwide. With a paucity of hydrological measurements, evidence from the field offers the only insight into truly extreme events and their variability in space and time. Historical, botanical, and geological archives have increasingly been recognized as valuable sources of extreme flood event information. These different archives are here reviewed with a particular focus on the recording mechanisms of flood information, the historical development of the methodological approaches and the type of information that those archives can provide. These studies provide a wealthy dataset of hundreds of historical and palaeoflood series, whose analysis reveals a noticeable dominance of records in Europe. After describing the diversity of flood information provided by this dataset, we identify how these records have improved and could further improve flood hazard assessments and, thereby, flood management and mitigation plans.
    Repository Name: EPIC Alfred Wegener Institut
    Type: Article , isiRev
    Format: application/pdf
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
  • 9
    facet.materialart.
    Unknown
    Copernicus Publications
    In:  EPIC3Hydrology and Earth System Sciences, Copernicus Publications, 25(12), pp. 6239-6259, ISSN: 1027-5606
    Publication Date: 2023-10-30
    Description: 〈jats:p〉Abstract. Natural flood management (NFM) is the name given to nature-based solutions (NBS) for flood management in the UK. It is a holistic flood management technique that employs natural hydrological processes, through the installation of interventions, to slow the flow of water, creating a landscape-scale flood management system. Despite widespread interest and supporting policy from governments and non-profit organisations, NFM, as yet, has not been widely adopted as a mainstream flood management technique. A small number of academic studies examining perceived barriers to NFM adoption have identified a variety of individual factors as being responsible. It is commonly accepted that flood risk management broadly, and NFM specifically, are complex, challenges of interacting physical and human parameters, and that academic, institutional and policy divisions are rarely sympathetic to embracing these complexities. A transdisciplinary problem-framing study in conjunction with professionals experienced in the delivery of NFM projects in the UK aimed to capture these multifaceted parameters of flood management and strategic delivery at a landscape scale using group concept mapping, a systems approach to identify conceptual convergence. This policy-delivery impasse was further explored by quantifying the relative importance of individual barriers and conceptual groupings from the perspective of two different practitioner groups (flood risk managers and conservation practitioners). The results demonstrate that the NFM delivery system can be grouped into seven interacting elements, policy and regulation, politics, public perception, cross-cutting issues, funding, technical knowledge and evidence, of which each has a varying number of barriers that limit NFM uptake. Opinions differ as to the importance of these individual barriers; however, when considering the system broadly we identify that the institutional and social barriers are perceived as the most important, whilst technical knowledge and evidence are the areas of least concern. This paper aims to promote NBS flood management delivery in the UK and globally by generating, structuring and representing the multifaceted and multilevel NFM delivery system at a local level to evidence adaptive decision making at regional, national and global levels. Through problem structuring and an increased understanding and awareness of the structure and network of linking elements and perceived differences of practitioner groups that influence the system of delivery, steps can be taken towards solutions that are socially, scientifically and practically robust. 〈/jats:p〉
    Repository Name: EPIC Alfred Wegener Institut
    Type: Article , peerRev
    Format: application/pdf
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...