Keywords:
Polyelectrolytes.
;
Electronic books.
Type of Medium:
Online Resource
Pages:
1 online resource (269 pages)
Edition:
1st ed.
ISBN:
9783642407468
Series Statement:
Advances in Polymer Science Series ; v.256
URL:
https://ebookcentral.proquest.com/lib/geomar/detail.action?docID=3093092
DDC:
541.372
Language:
English
Note:
Front Cover -- Preface -- Contents -- Polyelectrolyte Complexes for Tailoring of Wood Fibre Surfaces -- 1 Setting the Scene: Polyelectrolytes in Papermaking -- 2 Adsorption of PECs to Cellulose Fibres -- 3 PEC for Controlling Adhesive Properties of Fibres -- 3.1 PECs Produced In Situ -- 3.2 In Situ PEC Formation with Wood Components -- 3.3 Pre-formed PECs -- 4 What Controls the Adhesion? -- 5 Future Outlook -- References -- Polyelectrolyte Complexes in Flocculation Applications -- 1 Introduction -- 2 Dual Systems (Step-by-Step Addition) -- 2.1 Interaction with Cellulose (Paper Industry) -- 2.2 Interaction with Humic Acid -- 2.3 Removal of Minerals or Heavy Metals -- 2.4 Dual Systems Using ``New Polymers´´ -- 2.5 Dewatering and Sludge Conditioning -- 2.6 Surface Modification -- 2.7 Dual Systems with Thermosensitive Polymers -- 3 ``Direct´´ Interaction Between the Flocculant (PC) and an Anionically Charged Suspension -- 3.1 Paper Recycling -- 3.2 Sticky Removal -- 3.3 Natural Polymers for Sticky Removal -- 4 Pre-mixed PECs as Flocculants -- 4.1 Complex Formation and Characterization -- 4.2 Influence of Polymer Type on Complex Properties -- 4.3 Application of Pre-mixed Complexes as Flocculants -- 4.4 Polymer-Surfactant Complexes -- 4.5 Removal of Organic Pollutants -- 5 Current Trends and Future Research Directions -- 5.1 Advanced Characterization Methods -- 5.2 Use of Natural Polymers -- 6 Summary and Outlook -- References -- Spontaneous Assembly and Induced Aggregation of Food Proteins -- 1 Introduction -- 2 Structure and Properties of Some Food Proteins -- 2.1 General Aspects of Proteins -- 2.2 beta-Lactoglobulin -- 2.3 Serum Albumin -- 2.4 α-Lactalbumin -- 2.5 Ovalbumin -- 2.6 Caseins -- 2.7 Lactoferrin -- 2.8 Lysozyme -- 3 Induced Assemblies of Food Proteins -- 3.1 Fibrils -- 3.2 Multistranded Ribbons and Spherulites.
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3.3 Particulate Aggregates -- 3.4 Nanotubes -- 4 Spontaneous Assemblies of Food Proteins -- 4.1 Oppositely Charged Proteins and Polyelectrolytes -- 4.2 Oppositely Charged Proteins -- 5 Conclusion -- References -- Polyelectrolyte Complexes of DNA and Polycations as Gene Delivery Vectors -- 1 Introduction -- 1.1 DNA -- 1.1.1 Structure of DNA -- 1.1.2 Conformations of DNA -- 1.1.3 Topologies of DNA -- 1.1.4 DNA Condensation in Nature -- 1.2 Polyelectrolytes -- 1.2.1 Weak and Strong Polyelectrolytes -- 1.2.2 Manning Condensation and Effective Charge Density -- 1.3 DNA/Polycation Complexes -- 1.3.1 Factors Influencing the Complexation of DNA by Cationic Polymers -- 1.3.2 Condensation of DNA by Cationic Polymers -- Structural Models -- Cooperative Versus Non-cooperative Binding -- 1.3.3 Structure of Polyplexes -- Water-Soluble Polyplexes -- Colloidally Stable Polyplexes -- Without Steric Stabilization -- With Steric Stabilization -- Insoluble Polyplexes -- Polyplexes Based on Amphiphilic Polycations -- Influence of Salts -- 1.3.4 Characterization of Polyplexes -- Structural Characterization -- Charge Determination -- Strength of the Complexation -- 1.4 Application in Gene Therapy -- 1.4.1 Introduction to Gene Therapy -- 1.4.2 Requirements for Efficient Gene Therapy -- Complexation and Compaction/Condensation -- Extracellular Barriers and Physico-chemical Aspects -- Intracellular Processes -- Toxicity, Biocompatibility, and Biodegradability -- 2 Polycation/DNA Complexes -- 2.1 Water-Soluble Polycations -- 2.1.1 Strong Polyelectrolytes -- Containing Aromatics or Having a Charged Backbone -- With Side Chains Containing Quaternary Ammoniums -- 2.1.2 Weak Polyelectrolytes -- Without Steric Stabilizer -- Polyaspartamide Derivatives -- Other Polyamide Backbones -- PDMAEMA and Derivatives -- PNIPAM Derivatives -- PLL Derivatives -- Other Amino Acid-Based Polymers.
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PMMA and Methacrylamide Derivatives -- With Steric Stabilizer -- PDMAEMA Derivatives -- Linear PEI Derivatives -- PLL Derivatives -- Other Amino Acid-Based Polymers -- 2.2 Amphiphilic Polycations -- 2.2.1 Strong Polyelectrolytes with Alkyl Chains -- 2.2.2 Amphiphilic Polymers and Lipopolymers -- 2.2.3 Micelles of Amphiphilic Polymers and Lipopolymers -- 3 Polyampholyte/DNA Complexes -- 3.1 Polyzwitterions -- 3.1.1 Polycarboxybetaines -- 3.1.2 Polyphosphobetaines -- 3.1.3 Polysulfobetaines -- 3.2 Polyamphoters -- 4 Conclusion -- References -- Sizing, Shaping and Pharmaceutical Applications of Polyelectrolyte Complex Nanoparticles -- 1 Introduction -- 2 PEC Characterization and Preparation: Critical Experimental Aspects -- 2.1 Characterization -- 2.1.1 Static Light Scattering -- 2.1.2 Dynamic Light Scattering -- 2.1.3 Transmission Electron Microscopy -- 2.1.4 Scanning Electron Microscopy -- 2.1.5 Scanning Force Microscopy -- 2.2 Preparation -- 2.2.1 Determination of True Charge -- 2.2.2 Mixing Procedure -- 2.2.3 Order of Addition -- 2.2.4 Refinement -- 3 Sizing of PEC Particles -- 3.1 PEL Structural Parameters -- 3.1.1 Charge Density -- 3.1.2 Molecular Weight -- 3.1.3 PEL Topology: Linear Versus Branched -- 3.1.4 Selected Copolymers of Charged and Uncharged Functional Comonomers -- Ethylene Oxide Comonomers -- N-Isopropylacrylamide Comonomers -- Amphoteric Terpolymers of Oppositely Charged and Neutral Blocks -- 3.2 Media Parameters -- 3.2.1 Mixing Ratio -- 3.2.2 PEL Concentration -- 3.2.3 Salt Concentration -- Salt Addition During Complexation -- Salt Addition After Complexation -- 3.2.4 pH -- 3.3 Sizing the Internal Structural Density of PECs -- 3.3.1 Internal Structure of Singularized Nanoparticles -- 3.3.2 Internal Structure of PEC Aggregates -- 4 Shaping of PEC Particles -- 4.1 Spherical PEC Particles -- 4.2 Rod-like PECs.
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4.2.1 PECs of Synthetic Polyelectrolytes -- 4.2.2 Biorelated PEC of Charged Homopolypeptides -- Influence of the Complexing PEL -- Influence of pH -- PDADMAC/PLG: Influence of Salt Type -- Analogy to PEM Films -- 4.2.3 Simulation Work on Rod-Like PEC Particles -- 4.3 Toroid PEC -- 5 Pharmaceutical Applications of PEC Nanoparticles -- 5.1 General Aspects on Drug Delivery from Nanoparticles -- 5.2 Drug Delivery from PEC Systems -- 5.2.1 Drug-Loaded Macroscopic PEC Systems -- 5.2.2 Drug-Loaded PEC Particles -- PEC/Protein Carriers -- PEC/Polynucleotide Carriers -- Small Drug-Loaded PEC Particles -- 5.2.3 Adhesive Films of PEC Nanoparticles for Local Drug Administration -- 5.3 Interaction of PEC Particles with Cells and Biofluids -- 5.3.1 In Vitro Interaction of PEC Particles with Cells -- Interaction of PEC Particles with Cancer Cells -- Interaction of PEC Particles with Endothelial Cells -- Interaction of PEC Particles with Osteoblast Cells -- 5.3.2 In Vivo Interaction of PEC Particles with Blood -- 6 Summary and Outlook -- References -- Index.
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