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  • 1
    Keywords: Genomics. ; Electronic books.
    Description / Table of Contents: The study of early eukaryote evolution has changed drastically, with firm ideas being revised or abandoned after more sophisticated analyses of molecular sequence data. Organelles, Genomes and Eukaryote Phylogeny reviews the field ofdeep level phylogenetic inference of eukaryotes, especially regarding the origin and evolution of eukaryotic cells and their organelles. By interpreting data from molecular and cell biology, genome sequencing with respect to eukaryogenesis, and endosymbiotic events leading to mitochondria and plastids, this book proves relevant to all postgraduates and professionals in molecular systematics, comparative genomics and cell biology.
    Type of Medium: Online Resource
    Pages: 1 online resource (404 pages)
    Edition: 1st ed.
    ISBN: 9781134424801
    DDC: 571.6
    Language: English
    Note: Front cover -- Table of Contents -- 1 An overview on eukaryote origins and evolution: the beauty of the cell and the fabulous gene phylogenies 1 -- SECTION I Eukaryote Diversity and Phylogeny -- 2 Excavata and the origin of amitochondriate eukaryotes 27 -- 3 The evolutionary history of plastids: a molecular phylogenetic perspective 55 -- 4 Chromalveolate diversity and cell megaevolution: interplay of membranes, genomes and cytoskeleton 75 -- 5 Origin and Evolution of animals, fungi and their unicellular allies (Opisthokonta) 109 -- SECTION II Phylogenetics and Comparative Genomics -- 6 Pitfalls in tree reconstruction and the phylogeny of eukaryotes 133 -- 7 The importance of evolutionary biology to the analysis of genome data 153 -- 8 Eukaryotic phylogeny in the age of genomics: evolutionary implications of functional differences 171 -- 9 Genome phylogenies 189 -- 10 Genomics of microbial parasites: the microsporidial paradigm 207 -- 11 Evolutionary contribution of plastid genes to plant nuclear genomes and its effects on the composition of the proteomes of all cellular compartments 237 -- SECTION III Evolutionary Cell Biology and Epigenetics -- 12 Protein translocation machinery in chloroplasts and mitochondria: structure, function and evolution 259 -- 13 Mitosomes, hydrogenosomes and mitochondria -- variations on a theme? 289 -- 14 Eukaryotic cell evolution from a comparative genomic perspective: the endomembrane system 309 -- 15 The membranome and membrane heredity in development and evolution 335 -- 16 Epigenetic inheritance and evolutionary adaptation 353 -- Contributors -- Chapter 1 -- CONTENTS -- Abstract -- 1.1 Introduction -- 1.2 The Ribosomal RNA Paradigm and the Archezoa Hypothesis -- 1.3 From SSUrDNA Trees to Protein-Coding Gene Trees -- 1.4 Eukaryote Diversity and Phylogeny. , 1.5 Organelles of Endosymbiotic Origins,Their Genomes and Proteomes -- 1.6 Eukaryote Origins -- 1.7 The Cell - A Final Comment -- Acknowledgments -- References -- Chapter 2 -- CONTENTS -- Abstract -- 2.1 The Search for Primitive Eukaryotes -- 2.2 The Archezoa Hypothesis -- 2.3 Candidate Archezoa as Deep Branches -- 2.4 Challenges to the Archezoa Hypothesis -- 2.5 Excavata - A Home for Many Reformed Archezoa? -- 2.6 Morphological Evidence for Excavata -- 2.7 Molecular Phylogenies and Excavata -- Euglenozoa Heteroloboseid Jakobid -- Malawimonas Trimastix -- Diplomonads -- Carpediemonas Parabasalids -- 2.8 Relationships among Excavata -- 2.9 Excavates as Early Eukaryotes? -- 2.10 Alternatives to Mitochondria in Excavates -- 2.11 Excavate Phylogeny and Mitochondrial Loss - Neoarchezoa? -- Acknowledgments -- References -- Chapter 3 -- CONTENTS -- Abstract -- 3.1 Introduction -- 3.2 Primary Plastids -- 3.3 One Origin -- 3.4 Three Lineages -- 3.5 Secondary Plastids -- 3.6 Red and Green Endosymbionts -- 3.7 How Many Secondary Endosymbioses? -- 3.8 Loss of Photosynthesis: How Common Is It? -- 3.9 Tertiary Endosymbiosis, Serial Secondary Endosymbiosis -- 3.10 A Second Primary Endosymbiosis? -- Acknowledgments -- References -- Chapter 4 -- CONTENTS -- Abstract -- 4.1 Introduction: What Are Chromalveolates? -- 4.2 Diversity and Unity of Chloroplast Protein Targeting in Chromalveolates -- 4.3 Alveolate Cell and Organellar Diversity -- 4.4 Chromist Cell Diversification -- 4.5 Biogenesis of Cortical Alveoli -- 4.6 Evolution and Biogenesis of Chromalveolate Ciliary Hairs -- 4.7 Envoi -- References -- Chapter 5 -- CONTENTS -- Abstract -- 5.1 Introduction -- 5.2 Animals and Their Phylogeny -- 5.3 Fungi and Their Phylogeny -- 5.4 The Protistan Animal-Fungal Allies (Choanozoa) -- 5.5 Choanozoa Phylogeny and the Origin of Animals and Fungi. , 5.6 Possible Sistergroups of the Opisthokonta -- Opisthokonta Am oebozoa Apusozoa -- Apus -- 5.7 Conclusions -- Acknowledgments -- References -- Chapter 6 -- CONTENTS -- Abstract -- 6.1 Introduction -- ROOT -- 6.2 Pitfalls in Tree Reconstruction Methodologies -- 6.3 LGTs and the Quest for a Species Phylogeny -- 6.4 Toward a Resolution of the Eukaryotic Phylogeny? -- 6.5 Perspective -- Acknowledgment -- References -- Chapter 7 -- CONTENTS -- Abstract -- 7.1 Introduction -- 7.2 Cataloging Genes and Other Sequences and Understanding Their Placement in Gene Families -- 7.3 Comparative Genomics: Molecular Evolution and Natural Selection -- 7.4 Patterns in Genomes -- 7.5 Conclusions -- References -- Chapter 8 -- CONTENTS -- Abstract -- 8.1 Introduction -- 8.2 Red Algal and Green Plant Origins as a Case Study for Genomic Analyses -- 8.3 Do Genomic Studies Provide Clear Support for a Relationship between Green Plants and Red Algae? -- 8.4 Do Mitochondrial Genome Investigations Support a Red-Green Relationship? -- 8.5 Molecular and Biochemical Processes as Shared-Derived Characters -- 8.6 Major Innovations in How the Genome Is Expressed -- 8.7 An Overhaul of RNA Polymerase II Transcription? -- 8.8 Control of the Cell Cycle and Cellular Differentiation -- 8.9 Homologies in the Mechanisms of Homeotic Development -- 8.10 Conclusions -- Acknowledgment -- References -- Chapter 9 -- CONTENTS -- Abstract -- 9.1 Introduction -- 9.2 Methods -- 9.3 Results and Discussion -- 9.4 Envoi -- Acknowledgment -- References -- Chapter 10 -- CONTENTS -- Abstract -- 10.1 Introduction -- 10.2 The Fascinating Microsporidian World -- 10.3 Why Study Microsporidian Genomes? -- 10.4 E. cuniculi Genome Content -- 10.5 Microsporidial Genes Encoding Mitochondrial-Type Proteins -- 10.6 Conclusions -- Acknowledgments -- References -- Chapter11 -- CONTENTS -- Abstract -- 11.1 Introduction. , 11.2 How Many Nuclear Genes of Plants Are of Cyanobacterial Origin? -- 11.3 Reconstruction of More Recent Instances of Plastid-to-Nucleus Gene Transfers -- 11.4 Functions of Cyanobacterium-Derived Proteins in the Plant Cell -- 11.5 Why Have Plastids Retained a Genome? -- 11.6 Consequences of Plastid-to-Nucleus Gene Transfer for Transport, Signaling and Development -- 11.7 Conclusions -- Acknowledgments -- References -- Chapter 12 -- CONTENTS -- Abstract -- 12.1 Introduction -- 12.2 TOM and TIM Translocases of Mitochondria -- 12.3 TOC and TIC Translocases of Chloroplasts -- 12.4 Intraorganellar Protein Translocation -- Acknowledgment -- References -- Chapter 13 -- CONTENTS -- Abstract -- 13.1 Introduction -- 13.2 Derived Mitochondrial Organelles -- 13.3 Morphology -- 13.4 Metabolic Capacity -- 13.5 Biogenesis -- 13.6 Evolutionary Considerations: A Common Selective Force? -- 13.7 Conclusions -- Acknowledgments -- References -- Chapter 14 -- CONTENTS -- Abstract -- 14.1 Introduction -- 14.2 The Endomembrane System -- 14.3 Mining the Databases -- 14.4 Endomembrane System Component Homologues in Diverse Genomes -- 14.5 Beyond BLAST: Examples from Functional Studies -- 14.6 Conclusions -- 14.7 Materials and Methods -- Acknowledgments -- References -- Chapter 15 -- CONTENTS -- Abstract -- 15.1 Introduction: Supramolecular Preformed Structure Is Important in Cell Heredity -- 15.2 DNA and Membrane Heredity Compared -- 15.3 The Membranome: Genetic Membranes and the Determinants of Membrane Identity -- 15.4 Stasis and Quantum Changes in the Membranome during Megaevolution -- 15.5 Lipid Targeting and Membrane Polarity -- 15.6 Biogenesis of Multiple Membrane Systems as an Epigenetic Constraint on Evolution -- 15.7 Membranes, Cell Skeletons and Genomes Interact to Build and Maintain Organisms -- 15.8 Envoi -- References -- Chapter 16 -- CONTENTS -- Abstract. , 16.1 Introduction -- 16.2 Steady-State Systems -- 16.3 Structural Inheritance -- 16.4 Inheritance of Chromatin Marks: Some Mechanistical Considerations -- 16.5 Inheritance of Chromatin Marks through Meiosis -- 16.6 Evolutionary Potential -- 16.7 Discussion -- References -- Index -- A -- B -- C -- D -- E -- F -- G -- H -- I -- J -- K -- L -- M -- N -- O -- P -- R -- S -- T -- U -- V -- W -- X -- Y -- Z -- Back cover.
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  • 2
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Science Inc
    The @journal of eukaryotic microbiology 52 (2005), S. 0 
    ISSN: 1550-7408
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology
    Notes: Membrane transport is crucial to eukaryotic cell function and its evolution is likely to be critical for eukaryogenesis. Tetrameric adaptin complexes form part of the transport machinery, selecting cargo for transport through the late secretory and endocytic systems. With a few protistan exceptions, the majority of adaptin studies have been performed on animal and yeast models. Trypanosomatids and yeast have a minimal complement of adaptin genes, while humans and Arabidopsis show a moderate expansion. This expansion is functional, with adaptin subunit isoforms substituting combinatorially into their complex to provide novel localization. To address questions of evolution, parasitology and comparative cell biology, we examined the adaptin complexes of the sexually transmitted parasite Trichomonas vaginalis. In coordination with the T. vaginalis genome project at The Institute for Genomic Research, we identified all adaptin genes in the current 3.3X genome coverage data (). Surprisingly, T. vaginalis has massively and differentially expanded its adaptin arsenal, with six times as many genes as other unicellular organisms examined and three times as many multicellar organisms. Eight Trichomonas adaptins have been confirmed by cDNA, demonstrating concurrent expression of the same gene. Phylogenetic analysis shows that the duplications giving rise to the various adaptin subfamilies occurred prior to the last common ancestor of diverse protists. Our data provide important insight into the evolution of the adaptin complex and the complexity of the Trichomonas late secretory/endocytic system. The differential expansion may illustrate the relative functional importance of the adaptin subfamilies to Trichomonas and be a model in which to study the lesser expansion seen in other eukaryotes. Finally, the size of the expansion, and the concurrent expression of at least one gene, suggests that the combinatorial nature of the adaptin complex may be more important than previously expected.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1365-2958
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology , Medicine
    Notes: The hydrogenosomal malic enzyme (ME) was purified from the anaerobic fungus Neocallimastix frontalis. Using reverse genetics, the corresponding cDNA was isolated and characterized. The deduced amino acid sequence of the ME showed high similarity to ME from metazoa, plants and protists. Putative functional domains for malate and NAD+/NADP+ binding were identified. Phylogenetic analysis of the deduced amino acid sequence of the new ME suggests that it is homologous to reference bacterial and eukaryotic ME. Most interestingly, the cDNA codes for a protein which contains a 27-amino-acid N-terminus which is not present on the purified mature protein. This presequence shares features with known mitochondrial targeting signals, including an enrichment in Ala, Leu, Ser, and Arg, and the presence of an Arg at position –2 relative to amino acid 1 of the mature protein. This is the first report of a mitochondrial-like targeting signal on a hydrogenosomal enzyme from an anaerobic fungus and provides support for the hypothesis that hydrogenosomes in Neocallimastix frontalis might be modified mitochondria.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    FEMS microbiology letters 117 (1994), S. 0 
    ISSN: 1574-6968
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology
    Notes: Abstract Most of the small ciliate protozoa, including Dasytricha ruminantium and Entodinium spp. living in the rumen of sheep, were found to have intracellular bacteria. These bacteria were not present in digestive vacuoles. They showed characteristic coenzyme F420 autofluorescence and they were detected with a rhodamine-labelled Archaea-specific oligonucleotide probe. The measured volume percent of autofluorescing bacteria (1%) was close to the total volume of intracellular bacteria estimated from TEM stereology. Thus it is likely that all of the bacteria living in the cytoplasm of these ciliates were endosymbiotic methanogens, using H2 evolved by the host ciliate to form methane. Intracellular methanogens appear to be much more numerous than those attached to the external cell surface of ciliates.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    [s.l.] : Macmillian Magazines Ltd.
    Nature 418 (2002), S. 865-869 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Microsporidia are obligate intracellular parasites of several eukaryotes. They have a highly complex and unique infection apparatus but otherwise appear structurally simple. Microsporidia are thought to lack typical eukaryotic organelles, such as mitochondria and peroxisomes. This has been ...
    Type of Medium: Electronic Resource
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  • 6
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Hydrogenosomes are double-membraned ATP-producing and hydrogen-producing organelles of diverse anaerobic eukaryotes. In some versions of endosymbiotic theory they are suggested to be homologues of mitochondria, but alternative views suggest they arose from an anaerobic bacterium that was ...
    Type of Medium: Electronic Resource
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  • 7
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Entamoeba histolytica is an intestinal parasite and the causative agent of amoebiasis, which is a significant source of morbidity and mortality in developing countries. Here we present the genome of E. histolytica, which reveals a variety of metabolic adaptations shared with two other ...
    Type of Medium: Electronic Resource
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