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  • 1
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    PANGAEA
    In:  Supplement to: Tremblay, Nelly; Caamal-Monsreal, Claudia; Ortega, Karen; Díaz, Fernando; Celdrán, David; Rosas, Carlos (in review): Measurement of aerobic scope during the whole embryonic development of a cephalopod. Marine Biology
    Publication Date: 2023-02-16
    Description: In the context of global warming, the present study aimed to identify at which stages the embryos of the holobenthic species Octopus maya are the most sensitive to temperature. We used temperature as a tool to induce minimum (TIMR-min: 11°C) and maximum metabolic rates (TIMR-max: 30°C) on embryos that came from three wild females caught off Sisal harbor (21°10'N, 90°02'W; Yucatán, Mexico) in March 2016. Higher metabolic rate values were recorded at stages XV and XVI, when the three hearts start beating, compared to stage X, when organogenesis begins. The factorial metabolic scope (FMS = TIMR-max ? TIMR-min) was higher at stages XV and XVI than the more mature stages, establishing stage XVII as the most vulnerable. High temperature exposure applied only during the earliest developmental stages (until stage XV) could have adaptive advantages if spawning occurs during hot waves in tropical coastal zones where the embryos are incubated or used for aquaculture purposes by shortening the time before hatching without physiological costs.
    Keywords: Method comment; off_Sisal_Harbor; Oxygen consumption per wet mass; Stage; Temperature, water
    Type: Dataset
    Format: text/tab-separated-values, 1164 data points
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  • 2
    Publication Date: 2024-03-20
    Description: The damselfish Neopomacentrus cyanomos were collected twice under an oil-loading platform 1.5 km from the Cayo Arcas reef (20.21°N, −91.98°W), in August 2016 (n = 16) and August 2017 (n = 30). All fish sampled in August 2016 were submitted to an acute-thermal-decline protocol (−4 °C over a period of 1 h, and maintaining the temperature for 23 h), while the ones collected in August were acclimated 45 days at 18, 20, 22, and 26 °C. Finally, half of the acclimated fish were submitted to a high temperature challenge to assess the effect of cold thermal acclimation on heat tolerance scope. Data of routine metabolic rates, blood metabolites and biochemical stress indicators from each fish are provided in this data set.
    Keywords: Acetylcholinesterase activity, unit per protein mass; Carbonyl, per wet mass; Carboxylesterase activity, unit per protein mass; Catalase activity, unit per protein mass; Citrate synthase activity, unit per protein mass; Experimental treatment; Glucose; Glutathione, reduced, per wet mass; Glutathione S-transferase activity, unit per protein mass; Gulf of Mexico; Lactate; Lactate dehydrogenase activity, unit per protein mass; Lipid peroxidation; Metabolic rate of oxygen per wet mass, routine; off_Cayo_Arcas_reef; Oxidation reduction (RedOx) potential; Superoxide dismutase activity, unit per protein mass; Treatment: temperature; Wet mass
    Type: Dataset
    Format: text/tab-separated-values, 702 data points
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  • 3
    ISSN: 1460-9568
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The present study investigated whether the ‘psychological threat’ induced by sensory contact with an aggressive conspecific would be a sufficient factor in inducing behavioural and physiological disturbances. Repeated sensory contact with an aggressive mouse (social threat) in a partitioned cage was compared with repeated exposure to a novel partitioned cage in male NMRI mice. We first examined parameters of stress responsiveness (body weight, plasma corticosterone levels, frequency of self-grooming and defecation). The temperature and physical activity responses to stress were also recorded during and after the 4 weeks of stress using radiotelemetry. Finally, cognitivo-emotional performance was assessed after acute stress and 2 and 4 weeks of stress by measuring decision making, sequential alternation performance and behaviour in the elevated T-maze. Social threat had a greater impact than novel cage exposure on most parameters of stress responsiveness, although mice did not habituate to either stressor. Social threat rapidly led to an anticipatory rise in core body temperature and physical activity before the scheduled stress sessions. Such anticipation developed within the first week and persisted for 9 days after ending the stress procedure. Some memory impairment in the sequential alternation test was found in stressed mice, independent of the stressor. After 4 weeks of stress, inhibitory avoidance in the elevated T-maze was enhanced in socially stressed mice and reduced in novel cage mice. The sustained anticipation of stress in the social threat group preceded aversive responding. It remains to be established whether anticipation contributes to the development of aversive responses.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Annals of the New York Academy of Sciences 411 (1983), S. 0 
    ISSN: 1749-6632
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Natural Sciences in General
    Type of Medium: Electronic Resource
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  • 5
    ISSN: 1432-0568
    Keywords: Human cerebral capillaries ; Pericytes ; Endothelium ; Gap junctions
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Human cerebral tissue has been ultrastructurally studied and gap junctions have been visualized between endothelial cells and pericytes that permit ion exchange. We propose that the functional interrelationship between endothelium and pericytes may play a role in the alteration of capillary diameter for the control of local cerebral blood flow.
    Type of Medium: Electronic Resource
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  • 6
    ISSN: 1432-0533
    Keywords: Key words Reperfusion ; Cerebral blood flow ; Vascular smooth muscle cell ; Pericyte ; Scanning ; electron microscopy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The present study was undertaken to ascertain the role of smooth muscles and pericytes in the microcirculation during hyperperfusion and hypoperfusion following ischemia in rats. Paired external carotids, the pterygopalatine branch of the internal carotids and the basilar artery were exposed and divided. Reversible inflatable occluders were placed around the common carotids. After 24 h, the unanesthetized rat underwent 10-min ischemia by inflating the occluders. Continuous cortical cerebral blood flow (c-CBF) was monitored by laser Doppler flowmetry. The measured c-CBF was below 20% of control (P 〈 0.001) during ischemia. A c-CBF of 227.5 ± 54.1% (P 〈 0.001) was obtained during reperfusion hyperemia. A c-CBF of 59.7 ± 8.8% (P 〈 0.001) occurred at the nadir of postischemic hypoperfusion, and this was followed by a second hyperemia. The cytoarchitecture of the vascular smooth muscles and pericytes was assessed by scanning electron microscopy. Samples were prepared using a KOH-collagenase digestion method. In control rats, arteriolar muscle cells showed smooth surfaces. Capillary pericytes were closely apposed to the endothelium. Immediately after reperfusion, transverse membrane creases were observed on the smooth muscle surfaces. During maximal hyperemia the creases disappeared. When c-CBF started to decrease the creases became visible again. Throughout the postischemic hypoperfusion the creases remained. Capillary endothelial walls became tortuous in the late phase of hypoperfusion. During the second hyperemia most arteriolar muscle cells showed smooth surfaces. Some pericytes appeared to have migrated from the vascular wall. The morphological changes of smooth muscle membranes suggest that they are related to specific perfusional disturbances during ischemia and reperfusion.
    Type of Medium: Electronic Resource
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  • 7
    ISSN: 1573-8752
    Keywords: Arteriovenous malformation ; γ knife ; LINAC ; radiosurgery
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract From September 1991 to May 1997, a total of 59 patients diagnosed with cerebral arteriovenous malformations were treated using radiosurgery. There were 29 men and 30 women, with an age range of 5 to 75 years (mean 36). Of these patients, 39 patients were treated using a LINAC-based system (group 1) and 20 using the Leksell γ-knife unit (group 2). Tumor volume ranged from 0.38 to 35 cc, and the number of isocenters varied from 1 to 3 in group 1 and from 2 to 15 in group 2. Lesion location was as follows: 14 temporal, 8 basal ganglionic, 8 frontal, 6 parietal, 6 thalamic, 5 intraventricular, 5 cerebellar, 3 brain stem, 3 occipital, and 1 corpus callosal. Seven patients underwent prior embolization and three patients had prior surgery with incomplete resection of their lesions. The marginal radiation dose ranged between 1500 and 2000 cGy with a mean of 1800 cGy. Twelve patients had concomitant embolization done on the morning of radiosurgery. Follow-up ranged from 1 month to 4 years. Thirty-six patients have been followed for more than 1 year. Thirty had an angiography during the follow-up period that showed complete obliteration of the lesion in 28 patients. The rate of obliteration was estimated to be 47.1% at 1 year, 82.3% at 2 years and 88.2% at 3 years.
    Type of Medium: Electronic Resource
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  • 8
    ISSN: 1573-8752
    Keywords: Brainstem ; stereotactic radiosurgery ; γ-knife ; performance status
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Stereotactic radiosurgery (SRS) is increasingly being used for tumors of the brainstem because it suits the anatomical constraints of this area. We now report on the 2-year experience at Wayne State University using γ-knife SRS for such lesions, with an emphasis on toxicity and morbidity. From January 1996 to January 1998, sixteen patients (6 males and 10 females) with lesions in the area of the brainstem were treated with SRS. Average age was 53 years (range 19–80). Nine lesions were malignant; 7 were benign. Median Karnofsky performance status (KPS) prior to SRS was 80 (range 50–100). Median follow-up period from initial diagnosis to analysis, and from the date of SRS to analysis, was 24 months (range 11–73) and 15 months (range 4–29), respectively. Results were analyzed for the whole population treated and then stratified by diagnosis: benign versus malignant. At analysis, 10 (62.6%) patients were alive and 6 (37.5%) were dead. No deaths followed SRS. Values for KPS prior to SRS were compared to 3 months post-SRS. No significant change in KPS scores could be observed for those with benign lesions, but 67% of patients with malignant tumors showed a KPS drop ≥30 points. There was no correlation between the treated volume and survival. At the time of review, no patients had developed new neurological symptoms after SRS. Results for benign lesions indicate that SRS is well tolerated, provides good local control, and does not cause unusual rates of morbidity or mortality. Results for malignant lesions demonstrate that pretreatment performance status influences the post-SRS values. The post-SRS Median Survival (MS) of 10 months for the Malignant Lesions (M) is impressive, in light of the drop of KPS observed; the outcome for such patients is likely determined by the activity of the primary disease process. Our results suggest that SRS in the brainstem is safe, feasible, and merits further study.
    Type of Medium: Electronic Resource
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  • 9
    ISSN: 1573-8752
    Keywords: Brachytherapy ; implants ; iodine-125 ; low-grade glioma
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We report a retrospective study on the use of the permanent iodine-125 (125I) implants in the management of low-grade gliomas. From July 1988 to July 1997, 16 patients with low-grade gliomas underwent permanent 125I implants in the management of their lesions. There were 7 males and 9 females ranging in age from 4 to 48 years (mean 19). The location was in the cerebral hemisphere in 7 patients, brainstem in 5 patients and thalamus/basal ganglia in 4 patients. Prior to brachytherapy, 9 patients underwent surgical resection and 7 patients underwent stereotactic biopsy procedures. Fourteen patients were treated as part of the initial management and 2 were recurrent. The histological diagnosis was: 9 WHO grade II astrocytomas, 3 oligodendrogliomas, 2 gemistocytic astrocytomas, 1 pilocytic astrocytoma, and 1 ependymoma. The tumor volume ranged from 0.7 to 33.4 cc (mean 8.4). Stereotactic treatment planning was used to encompass the contrast-enhancing rim of the tumor visualized by computerized tomography with an initial dose rate of 0.05 Gy/hour with 125I. The total activity ranged from 0.8 to 20.5 mCi. With a median follow-up period of 35 months (range, 4–105 months), the 2- and 5-year survival rates were 93.7% and 87.5%, respectively. Three patients underwent reoperation after implants, two of three had recurrent disease, and one had radiation necrosis. Permanent 125I implants appear to be safe and effective as a part of the multimodality management of low-grade gliomas.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Springer
    Bulletin of environmental contamination and toxicology 41 (1988), S. 496-501 
    ISSN: 1432-0800
    Source: Springer Online Journal Archives 1860-2000
    Topics: Energy, Environment Protection, Nuclear Power Engineering , Medicine
    Type of Medium: Electronic Resource
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