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  • 1
    Electronic Resource
    Electronic Resource
    The supine position for transsphenoidal surgery (1994)
    Springer
    Neurosurgical review 17 (1994), S. 275-276 
    Details
    ISSN: 1437-2320
    Keywords: Operative Position ; pituitary neoplasms ; transsphenoidal microsurgery
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The supine position has been routinely used for transphenoidal microsurgery in our department since 1973. We had 404 patients, 387 of whom had pituitary microor macroadenomas. It is always satisfactory, allowing a very good control of intraoperative arterial pressure and prevention of air embolism. It is also comfortable for both surgeons.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00306817
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  • 2
    Electronic Resource
    Electronic Resource
    Choice of neurosurgical approach in the treatment of cranial base lesions (1994)
    Springer
    Neurosurgical review 17 (1994), S. 109-125 
    Details
    ISSN: 1437-2320
    Keywords: Skull base-tumors-approach
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The authors describe a series of surgical approaches that they found particularly useful for the exposure and removal of lesions involving the skull base. These are: 1) fronto-naso-orbital approach; 2) frontotemporo-orbito-zygomatic approach; 3) subtemporal transpetrosal approach; 4) temporo-suboccipital transpetrosal approach (retrolabyrinthine presigmoid; transsigmoid; translabyrintine amend transcochlear presigmoid); 5) dorsolateral approach to the foramen magnum and lower clivus. As the approaches are complex and carry potential risks of morbidity, not only it is important to have a good knowledge of basic anatomy but also to closely follow the indications for each one. In this type of surgery where it is often difficult to achieve complete removal of the lesion by a single route of attack, more than one approach may be employed in different surgical steps. Finally, all these approaches demand extremely scrupulos surgical reconstruction to avoid dangerous postoperative complications that may jeopardize the previous work of the surgeon.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00698763
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  • 3
    Electronic Resource
    Electronic Resource
    Medulloblastoma in pediatric age: a single-institution review of prognostic factors (1995)
    Springer
    Child's nervous system 11 (1995), S. 80-84 
    Details
    ISSN: 1433-0350
    Keywords: Medulloblastoma ; Pediatric brain tumor ; Radiotherapy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We report a retrospective study of 35 cases of medulloblastoma in pediatric patients treated at our institution during an 18-year period. Ten of the patients were infants (age 〈2 years) and 25 were children (age 〉2 years). The main factors affecting prognosis were total removal of the tumor (P〈0.01) and tumor stage (P〈0.01). There were no differences between the survival rate of infants and children, infants had a worse prognosis in regard to quality of life than children.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00303809
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  • 4
    Electronic Resource
    Electronic Resource
    Intramedullary astrocytomas and ependymonas in the pediatric age group: a retrospective study (1996)
    Springer
    Child's nervous system 12 (1996), S. 776-780 
    Details
    ISSN: 1433-0350
    Keywords: Childhood ; Intramedullary astrocytoma ; Intramedullary ependymoma ; Prognosis ; Treatment
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract A series of 45 pediatric patients underwent surgery for intramedullary astrocytoma or ependymoma at the Cook County Hospital or the Children's Memorial Hospital of Chicago (Northwestern University) and the Neurosurgical Department of Rome “La Sapienza” University. Results showed that intramedullary astrocytomas and ependymomas in children differ from one another in terms of prognosis, and particularly as regards surgical strategy as an element of therapeutic management. Gross total removal of 70% of the ependymonas was achieved, in comparison to 33% of the astrocytomas. In astrocytomas the extent of resection did not significantly influence prognosis. Neurological condition on admission, regardless of oncotype, was found to be extremely influential: patients operated in good condition tended to remain neurologically stable or improve in the long term, while those operated on while in poor condition did not show any improvement at all. No definitive conclusions were possible regarding the value of radiotherapy, because it was only performed in 6 of the 45 cases. The authors limited its use to highly malignant lesions in view of the well-known sensitivity of the spinal cord to radiation, especially in children.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00261597
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  • 5
    Electronic Resource
    Electronic Resource
    Post-radiation glioma in a child (1988)
    Springer
    Child's nervous system 4 (1988), S. 296-301 
    Details
    ISSN: 1433-0350
    Keywords: Glioma ; Postradiation tumors ; Lymphocytic leukemia ; Pediatric cancer
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract A case of primary brain neoplasm is reported that developed 11 years after prophylactic brain irradiation and intrathecal methotrexate (MTX) given for acute lymphocytic leukemia (ALL) at the age of 3 years. Cases of supposed postirradiation gliomas in children seem to have increased in recent years, particularly following apparently successful treatment for ALL or medulloblastoma. This increse might reflect the increased number of long-surviving cancer children and thus suggest that brain irradiation may be a potential risk factor in this population. After reviewing some general data on neurooncogenesis, two points are stressed: (1) the child's brain is particularly susceptible to the mutagenic effects of ionizing radiation owing to physiologically active postnatal glial cell proliferation, which takes place in the cerebral hemispheres, especially during myelinogenesis; (2) MTX could promote glial neoplasm by enhancing reparative glial cell proliferation. Prospective studies seem necessary to show whether or not prophylactic brain radiaton in ALL plays an oncogenetic role. Nevertheless, besides recurrent leukemia, leukoencephalopathy, and radionecrosis, the remote possibility of radiation-induced glial neoplasma should always be considered in cases of children treated for leukemia who present with neurological complications.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00271927
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  • 6
    Electronic Resource
    Electronic Resource
    Recurrence from filum terminale ependymoma 42 years after ’total‘ removal and radiotherapy (1997)
    Springer
    Journal of neuro-oncology 34 (1997), S. 153-156 
    Details
    ISSN: 1573-7373
    Keywords: ependymoma ; filum terminale ; recurrence ; treatment
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The authors describe the unusual case of apatient requiring reoperation for ependymoma of the filumterminale after a symptom-free period of 42 years:treatment of the primary tumor consisted of macroscopicallycomplete surgical excision and postoperative radiotherapy.This case brings to light some interesting observations:a late recurrence, as in the case reportedhere, appears to be rare especially if thetumor presents in adult age; the long preoperativeclinical history (26 months) and the initial aspectof the tumor that infiltrated 2 caudal roots,removed together with the tumor, may have beenfactors correlated with the risk of recurrence: postoperativeradiotherapy may have helped to delay clinical manifestationof the recurrence.Ependymomas of the filum terminale may clinically recureven after complete removal. The latest clinical recurrencedescribed in the literature occurred after 26 years.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1005787422825
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  • 7
    Electronic Resource
    Electronic Resource
    Medulloblastoma in late adults: report of two cases and critical review of the literature (1994)
    Springer
    Journal of neuro-oncology 19 (1994), S. 169-173 
    Details
    ISSN: 1573-7373
    Keywords: medulloblastoma ; adults ; posterior fossa tumour
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The authors describe two cases of medulloblastoma occurring in two men aged 71 and 67 years respectively. Medulloblastoma in late adults (older than 65 years) is an exceptional occurrence, and in this age group is generally of the classic type. Our first case was exceptional for the long survival of the patient compared with those so far reported for the same age group.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01306459
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