ISSN:
1435-232X
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Medicine
Notes:
Summary Polymorphisms of the factor B and the second component of human complement were investigated in 220 unrelated healthy Koreans. In the BF system, three phenotypes, S, FS, and F, were observed, while no rare variants were detected. The estimated allele frequencies forBF * S andBF * F were 0.775 and 0.225 respectively. In the C2 system, one common phenotype, C, and three heterozygous types, BC, BHC, and ATC, were observed. The estimated allele frequencies forC2 * C,C2 * B,C2 * BH, andC2 * AT were 0.961, 0.018, 0.011, and 0.009, respectively. Significant positive association betweenC2 * AT andBF * F was found. Gene frequencies in Korean were compared with those in other populations.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01883668
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