ISSN:
1617-4623
Keywords:
Transposable element
;
Genetic instability
;
cut locus
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
Notes:
Summary Simultaneous multiple transpositions and longterm genetic instability have been described in the ct MR2 strain of Drosophila melanogaster and its derivatives. This strain originated from a cross that was dysgenic in the P-M system. While spontaneous instability declined over 2 years, instability has been reactivated by backcross to the progenitor P element bearing strain MRh12/Cy. We show here using germline transformation that active P factor alone cannot mimic the effect of this cross, suggesting that MRh12/Cy contains some other activator. In addition, we have observed that ct + exceptional progeny arise in the F1 s well as the F2 generations. Molecular analysis of X chromosomes from some ct + progeny indicates that phenotypic reversion of the ct mutation can arise through two unrelated mechanisms.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00331270
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