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  • Nuclear Structure  (5)
  • Open access, Epidemiology  (5)
  • Key words Oryza sativa L.  (3)
  • 1
    Electronic Resource
    Electronic Resource
    Analyzing quantitative trait loci for yield using a vegetatively replicated F2 population from a cross between the parents of an elite rice hybrid (2000)
    Springer
    Theoretical and applied genetics 101 (2000), S. 248-254 
    Details
    ISSN: 1432-2242
    Keywords: Key words Oryza sativa L. ; Ratoon ; Molecular marker ; QTL
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract  Although F2s are the most informative populations for genetic analysis, it has been difficult to use F2 populations directly for QTL analysis because it is usually difficult to assess the reliability of the data, due to an inability to estimate the experimental errors. In this study, we performed a QTL analysis for yield and yield-component traits of an F2 population based on data from replicated field trials over 2 years using vegetative shoots of ratooned plants, making use of the ratooning habit of rice. The objective of this study was to explore the possibility of conducting QTL analyses directly based on an F2 population by means of ratooning plants. The experimental population was from a cross between ’Zhenshan 97’ and ’Minghui 63’, the parents of ’Shanyou 63’, an elite rice hybrid widely grown in China. A genetic linkage map containing 151 molecular markers was constructed for QTL mapping. A total of 20 distinct QTLs were detected; eight of these were detected in both years and remaining 12 in only 1 year. Compared with the results of our previous analysis of the F2:3 families from the same cross, it was shown that most of the QTLs detected in the ratooned F2 population were also detected in the F2:3 population. However, the estimates of both additive and dominant types of genetic effects for many of the QTLs based on F2 ratoons were substantially larger than those based on F2:3 families. The results indicate that vegetatively ratooned F2 populations may have considerable utility in the mapping of QTLs, especially if dominant types of gene actions are of concern, although there were certain technical limitations in making use of such populations in the experiments.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s001220051476
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  • 2
    Electronic Resource
    Electronic Resource
    Differentiation and classification of parental lines and favorable genic interactions affecting F1 fertility in distant crosses of rice (Oryza sativa L.) (1998)
    Springer
    Theoretical and applied genetics 96 (1998), S. 526-538 
    Details
    ISSN: 1432-2242
    Keywords: Key words Oryza sativa L. ; Genetic differentiation ; Classification of parental lines ; Restriction fragment length polymorphism (RFLP) ; Genic interaction
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract  This study was intended to investigate the extent of genetic differentiation in parental lines of rice hybrids and to analyze the genetic basis underlying the fertility phenomenon in distant crosses. Two subsets of rice material (111 entries in total) were used, including 81 doubled-haploid (DH) lines and 30 Indica and Japonica rice varieties or lines (as a control). The DH lines was derived from a heterotic Indica/Japonica cross (Gui630/02428) by anther culture. The materials in the control represent a broad spectrum of the Asian cultivated rice gene pool including landraces, primitive cultivars, historically important cultivars, modern elite cultivars, super rice and parents of superior hybrids. In accordance with the NC II design, 57 out of the DH lines were test-crossed to two important wide compatibility lines: photoperiod-sensitive genetic male sterile (PGMS) line N422s and thermo-sensitive genetic male sterile (TGMS) line Peiai64s. The F1s and their parents, 182 entries in total, were examined for the performance of seven traits in a replicated field trial. All the rice materials was surveyed for polymorphisms using 92 RFLP markers selected from two published molecular marker linkage maps. Genotypes of the F1 hybrids at the molecular-marker loci were deduced from the parental genotypes. The analysis showed that there were two types of genetic differentiation in the two subsets of rice material; that is, qualitative differentiation in the control and quantitative differentiation in the DH lines. In addition, favorable genic interactions (both intra- or inter-locus) contributed to better increase the fertility in hybrids of distant crosses through incorporation of a wide-compatibility line as the female parent. Favorable genic interactions can be applied in hybrid rice breeding programs by selecting parents with an appropriate extent of genetic differentiation.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s001220050770
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  • 3
    Electronic Resource
    Electronic Resource
    The high level of wide-compatibility of variety ‘Dular’ has a complex genetic basis (1998)
    Springer
    Theoretical and applied genetics 97 (1998), S. 407-412 
    Details
    ISSN: 1432-2242
    Keywords: Key words Oryza sativa L. ; Indica-japonica cross ; Hybrid sterility ; Molecular marker ; Genetic analysis ; Epistasis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Wide-compatibility varieties (WCVs) are a special class of rice germplasm that is able to produce fertile hybrids when crossed to both indica and japonica rice varieties. WCVs may differ greatly in their spectrum and level of compatibility. The objective of this study was to determine the genetic basis of wide-compatibility conferred by ‘Dular’, a landrace variety from India that has demonstrated a high level of wide-compatibility in previous studies with a broad range of indica and japonica varieties. A three-way cross (‘Balilla/Dular//Nanjing 11’) was made and the resulting F1 population evaluated in the field for spikelet fertility. A total of 235 plants from this population was assayed individually for restriction fragment length polymorphisms (RFLPs) at 159 marker loci covering the entire rice genome at regular intervals. Quantitative trait locus (QTL) analysis identified 5 loci, located on chromosomes 1, 3, 5, 6 and 8, as having significant effects on hybrid fertility, which jointly explained 55.5% of the fertility variation in this population. The QTL on chromosome 5 ( f5) showed the largest effect on hybrid fertility, followed by those on chromosomes 6 ( f6), 3 ( f3) and 1 ( f1), with the one on chromosome 8 ( f8) having the smallest effect. Genotypes each composed of an allele from ‘Dular’ and an allele from ‘Nanjing 11’ at four ( f3, f5, f6 and f8) of the five QTLs contributed to the increase of fertility in the population. In contrast, the genotype composed of alleles from ‘Balilla’ and ‘Nanjing 11’ at the fifth locus ( f1) was in the direction of increasing fertility. Analysis of variance using marker genotypes at the five QTLs as the groups detected two interactions involving four of the five loci, a 2-locus interaction between f5 and f8 and a 3-locus interaction among f3, f5 and f6. The level of hybrid fertility is the result of complex interactions among these loci. The implication of the present findings in the utilization of the wide-compatibility of ‘Dular’ in rice breeding programs is also discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s001220050910
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  • 4
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    Infant BMI peak as a predictor of overweight and obesity at age 2 years in a Chinese community-based cohort (2017)
    BMJ Publishing
    In: BMJ Open
    Details
    Publication Date: 2017-10-08
    Description: Objectives Infant body mass index (BMI) peak has proven to be a useful indicator for predicting childhood obesity risk in American and European populations. However, it has not been assessed in China. We characterised infant BMI trajectories in a Chinese longitudinal cohort and evaluated whether BMI peak can predict overweight and obesity at age 2 years. Methods Serial measurements (n=6–12) of weight and length were taken from healthy term infants (n=2073) in a birth cohort established in urban Shanghai. Measurements were used to estimate BMI growth curves from birth to 13.5 months using a polynomial regression model. BMI peak characteristics, including age (in months) and magnitude (BMI, in kg/m 2 ) at peak and prepeak velocities (in kg/m 2 /month), were estimated. The relationship between infant BMI peak and childhood BMI at age 2 years was examined using binary logistic analysis. Results Mean age at peak BMI was 7.61 months, with a magnitude of 18.33 kg/m 2 . Boys (n=1022) had a higher average peak BMI (18.60 vs 18.07 kg/m 2 , p〈0.001) and earlier average achievement of peak value (7.54 vs 7.67 months, p〈0.05) than girls (n=1051). With 1 kg/m 2 increase in peak BMI and 1 month increase in peak time, the risk of overweight at age 2 years increased by 2.11 times (OR 3.11; 95% CI 2.64 to 3.66) and 35% (OR 1.35; 95% CI 1.21 to 1.50), respectively. Similarly, higher BMI magnitude (OR 2.69; 95% CI 2.00 to 3.61) and later timing of infant BMI peak (OR 1.35; 95% CI 1.08 to 1.68) were associated with an increased risk of childhood obesity at age 2 years. Conclusions We have shown that infant BMI peak is valuable for predicting early childhood overweight and obesity in urban Shanghai. Because this is the first Chinese community-based cohort study of this nature, future research is required to examine infant populations in other areas of China.
    Keywords: Open access, Epidemiology
    Electronic ISSN: 2044-6055
    Topics: Medicine
    Published by BMJ Publishing
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  • 5
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    Level structure in the transitional nucleus ^{195}Au (2012)
    American Physical Society (APS)
    Details
    Publication Date: 2012-02-07
    Description: Author(s): S. C. Wang, X. H. Zhou, Y. D. Fang, Y. H. Zhang, N. T. Zhang, B. S. Gao, M. L. Liu, J. G. Wang, F. Ma, Y. X. Guo, S. C. Li, X. L. Yan, L. He, Z. G. Wang, F. Fang, X. G. Wu, C. Y. He, Y. Zheng, Z. M. Wang, G. X. Dong, and F. R. Xu Excited states in 195 Au have been studied experimentally via the 192 Os( 7 Li, 4 n ) reaction at a beam energy of 44 MeV. Based on the γ - γ - t coincidence measurement, a level scheme consisting of 15 new transitions and 10 new levels is established for 195 Au. The triaxial shape-polarizing effect of the hig... [Phys. Rev. C 85, 027301] Published Mon Feb 06, 2012
    Keywords: Nuclear Structure
    Print ISSN: 0556-2813
    Electronic ISSN: 1089-490X
    Topics: Physics
    Published by American Physical Society (APS)
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  • 6
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    Identification of high-spin states in the stable nucleus ^{195}Pt (2011)
    American Physical Society (APS)
    Details
    Publication Date: 2011-07-15
    Description: Author(s): Y. D. Fang, Y. H. Zhang, X. H. Zhou, M. L. Liu, J. G. Wang, Y. X. Guo, X. G. Lei, W. Hua, F. Ma, S. C. Wang, B. S. Gao, S. C. Li, X. L. Yan, L. He, Z. G. Wang, F. Fang, X. G. Wu, C. Y. He, Y. Zheng, Z. M. Wang, Y. Shi, and F. R. Xu Excited states of the stable nucleus 195 Pt have been studied using an in-beam γ -ray spectroscopic technique following the incomplete fusion of 7 Li on an 192 Os target at 44 MeV. A level scheme built on the I π =13/2 + isomer has been established up to I π =33/2 − at an excitation energy of about 2.6 MeV. S... [Phys. Rev. C 84, 017301] Published Thu Jul 14, 2011
    Keywords: Nuclear Structure
    Print ISSN: 0556-2813
    Electronic ISSN: 1089-490X
    Topics: Physics
    Published by American Physical Society (APS)
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  • 7
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    Optimal Thromboprophylaxis in Elderly Chinese Patients with Atrial Fibrillation (ChiOTEAF) registry: protocol for a prospective, observational nationwide cohort study (2018)
    BMJ Publishing
    In: BMJ Open
    Details
    Publication Date: 2018-05-07
    Description: Introduction Atrial fibrillation (AF) is a worldwide healthcare burden that is associated with the ageing population. Elderly patients with AF with multiple comorbidities usually present with a high risk of thromboembolism and bleeding. Limited prospective data are available from Asian cohorts on the epidemiology and complications of AF. The present prospective cohort study aims to explore contemporary antithrombotic strategies among the elderly Chinese population in the new era of non-vitamin K antagonist oral anticoagulants and to compare the clinical characteristics and outcomes between Chinese and European AF populations. Methods and analysis The Optimal Thromboprophylaxis in Elderly Chinese Patients with Atrial Fibrillation (ChiOTEAF) registry will recruit 5000 patients with AF over 65 years of age in China. AF-related risks, including stroke/systemic thromboembolism and bleeding outcomes, will be assessed. Medical history, risk factors, demographic information and management will be collected at baseline, and clinical events during 1 year follow-up will be recorded. Follow-up will be conducted for at least 1 year and then annually thereafter. As our registry has a common protocol to the European Society of Cardiology EURObservational Research Programme AF general registry programme, preplanned analyses comparing the clinical profiles and outcomes will be performed. The ChiOTEAF registry offers an opportunity to provide a better understanding of the clinical profiles and adverse outcomes of patients with AF in China and allow for comparisons with a contemporary European population. Ethics and dissemination Ethics approval was granted by the Central Medical Ethic Committee of Chinese PLA General Hospital (approval no S2014-065-01). The (inter)national research presentations, peer-reviewed publications and media coverage of the research will be sued for dissemination of the results.
    Keywords: Open access, Epidemiology
    Electronic ISSN: 2044-6055
    Topics: Medicine
    Published by BMJ Publishing
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  • 8
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    Properties of the πh_{11/2} band in the stable nucleus ^{193}Ir (2011)
    American Physical Society (APS)
    Details
    Publication Date: 2011-05-27
    Description: Author(s): Y. D. Fang, Y. Shi, Y. H. Zhang, B. S. Gao, S. C. Wang, X. H. Zhou, M. L. Liu, J. G. Wang, F. Ma, Y. X. Guo, X. G. Wu, C. Y. He, Y. Zheng, Z. M. Wang, S. C. Li, X. L. Yan, L. He, Z. G. Wang, F. Fang, and F. R. Xu Excited states in the stable nucleus 193 Ir have been investigated through an in-beam γ -ray spectroscopic technique following the 192 Os ( 7 Li , α 2 n ) reaction at a beam energy of 44 MeV. A level scheme built on the π h 11/2 isomer has been extended to high-spin states using eleven newly observed γ transiti... [Phys. Rev. C 83, 054323] Published Thu May 26, 2011
    Keywords: Nuclear Structure
    Print ISSN: 0556-2813
    Electronic ISSN: 1089-490X
    Topics: Physics
    Published by American Physical Society (APS)
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  • 9
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    Risk factors of diabetic retinopathy and sight-threatening diabetic retinopathy: a cross-sectional study of 13 473 patients with type 2 diabetes mellitus in mainland China (2017)
    BMJ Publishing
    In: BMJ Open
    Details
    Publication Date: 2017-09-02
    Description: Objective To explore the risk factors of diabetic retinopathy (DR) and sight-threatening diabetic retinopathy (STDR) among Chinese patients with diabetes. Design, setting and participants A cross-sectional investigation was performed in eight screening clinics in six provinces across mainland China. Information about the risk factors was recorded in screening clinics. Some risk factors (sex, age, diagnosis age, diabetes duration, systolic blood pressure (SBP), diastolic blood pressure, fasting blood glucose (FBG) and glycosylated haemoglobin (HbA1c)) were recorded in all eight clinics, while others were collected only in a subset of the clinics. The relationships between the risk factors and DR and between the risk factors and STDR were explored for the eight factors mentioned above and for all factors studied. Main outcomes and measures Risk factors of DR and STDR were assessed, and a nomogram of the results was produced. Results Younger age, longer diabetes duration, higher SBP, higher FBG and higher HbA1c were found to be independent risk factors for both DR and STDR in the eight-factor analyses. In the all-factor analysis, younger age, longer diabetes duration, higher SBP, oral medicine use and insulin use were independent risk factors for both DR and STDR; higher postprandial blood glucose (PBG), HbA1c, triglyceride andlow-density lipoprotein were independent risk factors for DR only, and higher FBG was a risk factor for STDR only. Conclusions In this cross-sectional investigation, several risk factors were found for DR and STDR. Notably, FBG, PBG and HbA1c were all risk factors for DR or STDR, suggesting that stricter blood glucose control in clinical practice is required.
    Keywords: Open access, Epidemiology
    Electronic ISSN: 2044-6055
    Topics: Medicine
    Published by BMJ Publishing
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  • 10
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    The epidemiological profile of hysterectomy in rural Chinese women: a population-based study (2017)
    BMJ Publishing
    In: BMJ Open
    Details
    Publication Date: 2017-07-01
    Description: Objectives Hysterectomy is one of the most common surgical procedures performed on women in developed countries; however, little is known about the epidemiology of hysterectomy in low-income to middle-income regions. This study seeks to evaluate the prevalence of hysterectomy and its risk factors in rural China. Methods Questionnaires were collected from 3328 female adults aged 25â"69 years in rural Anyang, China, in 2009â"2011. Hysterectomy status was ascertained by the gynaecologist at the time of cytological test. Univariate and multivariate regression analyses were performed to assess the risk factors for hysterectomy. Results The overall prevalence of hysterectomy was 3.31% (110/3328). Women above the age of 40 years had a higher prevalence of prior hysterectomy, compared with those aged 25â"39 years (5.01% vs 0.33%). Obesity was marginally related with a higher risk of hysterectomy (adjusted OR=1.59; 95%âCI 0.99 to 2.56; body mass index (BMI) â¥28.0 vs 18.5 ⤠BMI 〈24.0). History of prior pregnancy loss conferred a greater risk for hysterectomy (adjusted OR=1.51; 95%âCI 1.02 to 2.23). Of the 75 (68.18%, 75/110) cases who provided further information on hysterectomy, 84.00% (63/75) had undergone total abdominal hysterectomy and 70.67% (53/75) had received surgery for leiomyoma. Conclusions Rural Chinese women had a relatively low prevalence of hysterectomy, and the majority of reported hysterectomies were performed abdominally for leiomyoma. Hysterectomy prevalence differed significantly by age, BMI and history of pregnancy loss. This study expands the current understanding of the epidemiology of hysterectomy in lower resource areas.
    Keywords: Open access, Epidemiology
    Electronic ISSN: 2044-6055
    Topics: Medicine
    Published by BMJ Publishing
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