GLORIA

GEOMAR Library Ocean Research Information Access

X
feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
Filter
  • Inorganic Chemistry  (19)
  • Ibuprofen  (2)
  • Ruthenium  (2)
  • 1
    Electronic Resource
    Electronic Resource
    Metallkomplexe mit biologisch wichtigen liganden - LXXI. Carbonyl-cyclopentadienyl-Eisen-, Ruthenium- und Wolfram-Komplexe von 1-Thioglucose
    Amsterdam : Elsevier
    Journal of Organometallic Chemistry 479 (1994), S. 217-220 
    Details
    ISSN: 0022-328X
    Keywords: Carbonyl ; Cyclopentadienyl ; Iron ; Ruthenium ; Thioglucose ; Tungsten
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0022-328X(94)84112-8
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    Kohlenwasserstoffverbruckte komplexe - XXIX. Nucleophile addition von carbonylmetallaten an kationische allyl- und alken-komplexe von wolfram, mangan, rhenium, eisen, ruthenium, osmium, cobalt und iridium: zwei-, drei- und vierkernige komplexe mit (sigma, pi-allyl- und sigma-sigma-alken-brucken
    Amsterdam : Elsevier
    Journal of Organometallic Chemistry 481 (1994), S. 45-55 
    Details
    ISSN: 0022-328X
    Keywords: Cobalt ; Iridium ; Iron ; Manganese ; Osmium ; Rhenium ; Ruthenium ; Tungsten
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0022-328X(94)85007-0
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    S-Ibuprofen versus ibuprofen-racemate (1991)
    Springer
    Rheumatology international 11 (1991), S. 199-202 
    Details
    ISSN: 1437-160X
    Keywords: Ibuprofen ; Enantiomers ; Rheumatoid arthritis ; Prostaglandins
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Ibuprofen (ibu) is a racemic 2-arylpropionic acid non-steroidal anti-inflammatory drug whose activity is due mainly to the S-enantiomer. So far only the racemic compound is in clinical use. A double-blind randomized trial was carried out for a 2-week period in 50 patients with classical rheumatoid arthritis (RA) (Steinbrocker II–III) to compare the effectiveness and tolerance of S-ibu (400 mg T.I.D.) with that of the racemic compound (600 mg T.I.D.). Ritchie-index, limitation of movement, joint pain on pressure and pain at night decreased significantly in both groups. Due to lack of effectiveness, the dose had to be increased in 3 patients from the S-ibu group as well as in 6 patients from the racemic group resulting in mean daily doses of 1220 mg S-ibuprofen and 1870 mg racemic ibu. No statistically significant difference could be found between both groups concerning efficacy and unwanted effects. Therefore, S-ibu given alone may be advantageous because the metabolic load to the human body is reduced and patients are more likely to comply with drug doses of 1.2 g/day as compared to 1.8 g/day.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00332562
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 4
    Electronic Resource
    Electronic Resource
    Gastrointestinal ulcerations induced by anti-inflammatory drugs in rats (1990)
    Springer
    Archives of toxicology 64 (1990), S. 210-217 
    Details
    ISSN: 1432-0738
    Keywords: Aspirin ; Diclofenac ; Diflunisal ; Ibuprofen ; Indomethacin ; Non-steroidal anti-inflammatory agents ; Gastrointestinal toxicity ; Prostaglandins ; Biliary excretion
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Aspirin, diclofenac, diflunisal, ibuprofen and indomethacin were given orally or intravenously to fasted or fed rats. The resulting gastric and intestinal damage was assessed using standard methods. The same drugs were administered to rats with biliary fitulas, and the fraction of drug excreted in bile was quantified using HPLC methods. We found that gastric damage occurred only in the fasted animals and was found to be dose-dependent and related to the amount (r=0.871) and solubility (r=0.909) of the individual drug. As far as acute gastric toxicity is concerned, neither the potency of a drug as an inhibitor of cyclo-oxygenase nor the fraction of unchanged or conjugated agent excreted in bile appeared to be relevant. Secondly, ulcerations of the small intestine occurred in fed animals only. The degree of damage was related to the amount of unchanged or conjugated drug excreted in bile and cyclo-oxygenase inhibitory potency (r=0.873). The administered dose (within the range investigated) and drug solubility appeared not to contribute to intestinal toxicity. It is concluded that, in the rat, acute gastric and intestinal toxicity of non-steroidal anti-inflammatory drugs are due to different mechanisms. Whereas gastric toxicity is strongly influenced by the amount of drug dissolved under the pH conditions in the stomach, intestinal toxicity appears to depend on biliary excretion and enterohepatic circulation of a drug as well as on its potency as an inhibitor of prostaglandin synthesis.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02010727
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 5
    Electronic Resource
    Electronic Resource
    Pseudohalogeno-Metallverbindungen. LXXV. Pentacarbonylrhenium-und Triphenylphosphangold-Komplexe mit Pseudohalogeniden: (OC)5ReX, Ph3PAuX (X = ONC(CN)2, o-MeC6H4SO2C(CN)2,o-MeC6H4SO2NCN, Ph2(S)PNCN) (1992)
    Weinheim : Wiley-Blackwell
    Zeitschrift für anorganische Chemie 617 (1992), S. 110-116 
    Details
    ISSN: 0044-2313
    Keywords: Pentacarbonylrhenium Complexes ; Nitrosodicyanmethanide ; o-Tosyldicyanmethanide ; o-Tosylcyanamide ; Diphenylthiophosphorylcyanamide ; Chemistry ; Inorganic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Description / Table of Contents: Pseudohalogeno Metal Compounds. LXXV. Pentacarbonylrhenium and Triphenylphosphinegold Complexes of Pseudohalide Anions: (OC)5ReX, Ph3PAuX (x = ONC(CN)2, o-MeC6H4SO2C(CN)2, o-MeC6H4SO2NCN, Ph2(S)PNCN)The pseudohalides (X-) nitrosodicyanmethanide, o-tosyldicyanmethanide, o-tosylcyanamide and diphenylthiophosphinylcyanamide react with the Organometallic Lewis Acids (OC)5Re+ (as (OC)5ReFBF3) and Ph3PAu+ (as Ph3PAuNO3) to give the neutral title complexes (OC)5Re - X and Ph3PAu—X, respectively. X-ray diffraction shows that nitroso-dicyanmethanide is coordinated through the nitroso N-atom to the Re(CO)5 fragment. Cyanide-N-coordination is observed for the complexes with o-tosyldicyanmethanide and o-tosylcyanamide whereas diphenylthiophosphinylcyanamide is S-coordinated to the gold atom. Spectroscopic data (IR, NMR) of 1-6 are described.
    Notes: Die Pseudohalogenide (X-) Nitrosodicyanmethanid, o-Tsyldicyanmethanid, o-Tosylcyanamid und Diphenylthiophosphinylcyanamid setzen sich mit den „Metallorganischen Lewis-Säuren“ (OC)5Re+(als (OC)5ReFBF3) und Ph3PAu+ (als ph3PAuNO3) zu den nautralen Titel-Komplexen (OC)5Re - X bzw. Ph3PAu—X um. Nach der Röntgenstrukturanalyse sind Nitrosodicyanmethanid über das Nitroso-N-Atom an das Re(CO)5-Fragment, o-Tosyl-dicyanmethanid und o-Tosyl-cyanamid über ein Cyanid-N-Atom an die Ph3PAu-bzw. (CO)5Re-Gruppe gebunden. Diphenylthiophosphinylcyanamid ist dagegen über das Schwefel-Atom an das Gold-Atom koordiniert. Die spektroskopischen Daten (IR, NMR) von 1-6 werden beschrieben.
    Additional Material: 4 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/zaac.19926170119
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 6
    Electronic Resource
    Electronic Resource
    Pseudoelementverbindungen. I. Zum Koordinationsverhalten von Diphenyl-cyanamido-thiophosphinat (1992)
    Weinheim : Wiley-Blackwell
    Zeitschrift für anorganische Chemie 617 (1992), S. 117-122 
    Details
    ISSN: 0044-2313
    Keywords: Cyanamido-thiophosphinate ; nickel(II) pseudohalide Complexes ; tetrapyridino-bis(diphenyl-cyanamido-thiophosphinato)-nickel(II) ; structure ; Chemistry ; Inorganic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Description / Table of Contents: Pseudoelement Compounds. I. Coordination Behaviour of Diphenyl-cyanamido-thiophosphinateThe synthesis of the cyanamido-thiophosphinate-nickel(II) complexes NipynX2 (X = Ph2P(S)NCN, n = 0, 2, 4) is reported and the i.r. and u.v. spectra of these compounds are discussed. The single crystal X-ray analysis of the tetrapyridine complex shows that the anionic ligand is coordinated via the cyano-nitrogen atom. With a bond angle N(1)—C(1)—N(2) of 175.4(3)° the NCN group is nearly linear. The bond distances N(1)—C(1) and C(1)—N(2) are asymmetric and typical of NC double and triple bonds.
    Notes: Die Synthese von Cyanamido-thiophosphinat-nickel(II)-Komplexen NipynX2 (X = Ph2P(S)NCN, n = 0, 2, 4) wird beschrieben und die IR- und UV-Spektren dieser Verbindungen werden diskutiert. Die Einkristall-Röntgenstrukturanalyse des Tetrapyridin-Komplexes zeigt, daß der anionische Ligand über das Cyano-Stickstoff-Atom koordiniert ist. Die NCN-Gruppe ist mit einem Winkel N(1)—C(1)—N(2) von 175,4(3)° nahezu linear. Die Bindungsabstände N(1)—C(1) und C(1)—N(2) sind asymmetrisch und typisch für NC-Doppel-bzw. Dreifachbindungen.
    Additional Material: 1 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/zaac.19926170120
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 7
    Electronic Resource
    Electronic Resource
    Über einen gemischten Cyano-fulminato-Komplex, Pentacyanofulminatoferrat(II) (1964)
    Weinheim : Wiley-Blackwell
    Zeitschrift für anorganische Chemie 333 (1964), S. 115-119 
    Details
    ISSN: 0044-2313
    Keywords: Chemistry ; Inorganic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Description / Table of Contents: By reaction of sodium pentacyanoammine-or aquoferrate(II) with sodium fulminate in water, diamagnetic Na4[Fe(CN)5CNO] is obtained. Pentacyanofulminatoferrate(II) is characterised by its chemical behaviour; by Fe(OH)2 it is reduced to [Fe(CN)6]4-. The infra red spectrum is discussed and compared with other pentacyanoferrates(II).
    Notes: Durch Umsetzung von Natrium-pentacyanoammin- oder aquoferrat(II) mit einer wäßrigen Lösung von Natriumfulminat wird diamagnetisches Natrium-pentacyanofulminatoferrat(II), Na4[Fe(CN)5CNO], erhalten. Das Pentacyanofulminatoferrat(II)-Ion wird durch sein chemisches Verhalten charakterisiert; mit Eisen(II)-hydroxid läßt es sich zu Hexacyanoferrat(II) reduzieren. Die IR-Absorptionsbanden des Komplexsalzes im Bereich von 2-40 m̈ werden zugeordnet und mit denjenigen anderer Natrium-pentacyanoferrate(II) verglichen.
    Additional Material: 2 Tab.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/zaac.19643330116
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 8
    Electronic Resource
    Electronic Resource
    Metall-tris(alkylsulfonyl)methanide (1968)
    Weinheim : Wiley-Blackwell
    Zeitschrift für anorganische Chemie 361 (1968), S. 147-156 
    Details
    ISSN: 0044-2313
    Keywords: Chemistry ; Inorganic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Description / Table of Contents: Metal tris(ethylsulfonyl)methanides, M[C(SO2C2H5)3]2 · 6 H2O (M = Mn, Co, Ni, Zn, Cd) are formed by reaction of HC(SO2C2H5)3 with metal carbonates. These methanides react with pyridine and o-phenanthroline to give the complexes M(py)2[C(SO2C2H5)3]2 (M = Mn, Co) and [M(o-phen)3][C(SO2C2H5)3]2, respectively. The ligand field spectra and the magnetic moments of the water-free compounds Co[C(SO2C2H5)3]2 and Ni[C(SO2C2H5)3]2 are consistent with a (pseudo)octahedral coordination of the metal ion. The infrared spectra of the acid HC(SO2C2H5)3 and of the anion [C(SO2C2H5)3]- are discussed.
    Notes: Durch Umsetzung von HC(SO2C2H5)3 mit Metallcarbonaten in wäßriger Lösung werden die Metall-tris(äthylsulfonyl)methanide Me[C(SO2C2H5)3]2 · 6 H2O (Me = Mn, Co, Ni, Zn, Cd) erhalten. Die Methanide reagieren mit Pyridin und o-Phenanthrolin unter Bildung der Komplexe Me(pyr)2[C(SO2C2H5)3]2 (Me = Mn, Co) bzw. Me(o-phen)3[C(SO2C2H5)3]2(Me = Mn, Co, Ni, Zn, Cd). Die Elektronenspektren und die magnetischen Momente der wasserfreien Salze Co[C(SO2C2H5)3]2 und Ni[C(SO2C2H5)3]2 können mit einer (pseudo-)oktaedrischen Umgebung des Zentralmetalls gedeutet werden. Die IR-Spektren der Säure HC(SO2C2H5)3 und des Anions [C(SO2C2H5)3]-, das sich als ein „schwacher“ Ligand erweist, werden mitgeteilt und diskutiert.
    Additional Material: 4 Tab.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/zaac.19683610306
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 9
    Electronic Resource
    Electronic Resource
    Darstellung und Reaktionen von DichlorotrinitrosylvanadinProfessor Helmut Behrens zum 60. Geburtstage am 30. Mai 1975 gewidmet (1975)
    Weinheim : Wiley-Blackwell
    Zeitschrift für anorganische Chemie 416 (1975), S. 97-105 
    Details
    ISSN: 0044-2313
    Keywords: Chemistry ; Inorganic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Description / Table of Contents: Preparation and reactivity of DichlorotrinitrosylvanadiumDichlorotrinitrosylvanadium is prepared by reaction of VCl4 with NO in CCl4 at 20°C. For [V(NO)3Cl2]n which is also formed from V(CO)6 and NOCl a structure with a trigonal pyramidal V(NO)3 group and with terminal and bridging chlorine ligands is proposed. [V(NO)3Cl2]n reacts with a range of N and O donors by substitution of two NO ligands to give mononitrosyl complexes V(NO)LnCl2; e.g. acetonitrile, o-phenanthroline, triphenylphosphine oxide afford the compounds [V(NO)L4Cl]Cl. The reaction of [V(NO)3Cl2]n with triphenylphosphine oxide and pyridine-N-oxide in CHCl3 proceeds by oxidation of vanadium and formation of the compounds VOL2Cl2 (L=OPPh3, C5H5NO).
    Notes: Dichlorotrinitrosylvanadin entsteht durch Umsetzung von VCl4mit NO in CCl4 bei 20°. Für [V(NO)3Cl2]n, das sich auch aus V(CO)6 und NOCl bildet, wird eine mehrkernige Struktur mit trigonal Pyramidaler V(NO)3-Gruppe sowie mit endständigen V-Cl-Bindungen und V-Cl-V-Brücken vorgeschlagen. [V(NO)3Cl2]n setzt sich unter milden Bedingungen mit N- und O-Basen unter Substitution von zwei NO-Liganden zu Mononitrosylkomplexen V(NO)LnCl2 um. Mit Acetonitril, o-Phenanthrolin, Triphenylphosphinoxid (in Benzol) werden die Verbindungen [V(NO)L4Cl]Cl erhalten. Triphenylphosphinoxid und Pyridin-N-oxid reagieren mit [V(NO)3Cl2]n in Chloroform unter Oxydation des Vanadins und Bildung der Oxovanadin(IV)-Komplexe VOL2Cl2 (L= OPPh3, C5H5NO).
    Additional Material: 2 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/zaac.19754160202
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 10
    Electronic Resource
    Electronic Resource
    Über anorganische Verbindungen des Stickoxyds. XI Dipolmomente von Dinitrosyleisen- und -kobaltverbindungen [Me(NO)2X]2 (Me = Fe:X = SC2H5, SeC2H5, Me = Co:X = Cl; Br) (1960)
    Weinheim : Wiley-Blackwell
    Zeitschrift für anorganische Chemie 305 (1960), S. 274-278 
    Details
    ISSN: 0044-2313
    Keywords: Chemistry ; Inorganic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Description / Table of Contents: In continuation of investigations on tricarbonyl iron compounds of the type [Fe(CO)3X]2 (X = SC2H5, SeC2H5), the dipol moments of the isoelectronic dinitrosyl compounds [Fe(NO)2SC2H5]2 and [Fe(NO)2SeC2H5]2 have been determined. From these a dipol-free model of [Fe(NO)2SeC2H5]2 and of the dinitrosyl cobalt monohalides [Co(NO)2Cl]2 and [Co(NO)2Br]2 containing selenium and halogen bridges, respectively, can be deduced.
    Notes: Im Anschluß an Untersuchungen über Tricarbonyleisenverbindungen des Typs [Fe(CO)3X]2 (X = SC2H5, SeC2H5) wurden auch die Dipolmomente der isoelektronischen Dinitrosylverbindungen [Fe(NO)2SC2H5]2 und [Fe(NO)2SeC2H5]2 bestimmt. Hieraus kann für [Fe(NO)2SeC2H5]2. sowie für die Dinitrosylkobaltmonohalogenide [Co(NO)2Cl]2 und [Co(NO)2Br]2 ein dipolfreies Modell mit Selen- bzw. Halogenbrücken abgeleitet werden.
    Additional Material: 3 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/zaac.19603050505
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...