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    Electronic Resource
    Electronic Resource
    Calcium release from frog sarcoplasmic reticulum by an imidazolyl reagent (1989)
    Springer
    Cellular and molecular life sciences 45 (1989), S. 987-991 
    Details
    ISSN: 1420-9071
    Keywords: Fragmented sarcoplasmic reticulum ; diethylpyrocarbonate ; calcium release ; Ca-ATPase
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Calcium is released from the isolated heavy sarcoplasmic reticulum (SR) of frog skeletal muscle upon application of 0.1–1 mM diethylpyrocarbonate (DEP, an imidazolyl reagent). The Ca-ATPase activity of SR was suppressed by 20% in the presence of 1 mM DEP. More than 1 mM of free magnesium ion or 5 μM ruthenium red eliminated the effect of DEP on calcium release but not on Ca-ATPase activity. A plausible site of DEP action is on the calcium channel.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01953058
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