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  • General Physics: Statistical and Quantum Mechanics, Quantum Information, etc.  (2)
  • Acetylcholine  (1)
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  • 1
    ISSN: 1432-2072
    Keywords: Dopamine ; Motivation ; Sedatives ; Acetylcholine ; Instrumental behavior ; Motor control ; Behavioral economics ; Reinforcement
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract This experiment was undertaken to provide a pharmacological characterization of performance on a task involving food-related instrumental and consummatory behavior. Rats were tested in an operant chamber in which there was a choice between pressing a lever to receive a preferred food (Bioserve pellets) or approaching and consuming a less-preferred food (Lab Chow). The lever pressing schedule was a fixed ratio 5 (FR5). Rats usually pressed the lever at high rates to obtain the preferred food, and typically ate little of the lab chow even though it was freely available in the chamber concurrently with the lever pressing schedule. Previous work has shown that injection of dopamine (DA) antagonists, or depletion of DA in the nucleus accumbens, caused a substantial shift in behavior such that lever pressing was reduced but chow consumption increased. In the present study it was shown that the DA antagonist haloperidol decreased lever pressing and increased chow consumption at doses of 0.1 and 0.15 mg/kg. The D1 antagonist SCH 23390 (0.05, 0.1 and 0.15 mg/kg) and the non-selective DA antagonistcis-flupenthixol (0.3 and 0.45 mg/kg) decreased lever pressing and produced substantial increases in chow consumption. The D2 antagonist sulpiride decreased lever pressing, but produced only slight increases in chow intake at the highest dose. Pentobarbital reduced lever pressing and increased chow consumption at 10.0 mg/kg. The muscarinic agonist pilocarpine produced dose-related decreases in lever pressing, but failed to increase chow consumption. Amphetamine produced dose-related decreases in both lever pressing and chow consumption. These results indicate that low/moderate doses of the DA antagonists haloperidol,cis-flupenthixol and SCH 23390 can suppress lever pressing in doses that leave the animal directed towards food acquisition and consumption.
    Type of Medium: Electronic Resource
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  • 2
    Publication Date: 2018-06-27
    Description: Author(s): Xiao-Ye Xu, Qin-Qin Wang, Wei-Wei Pan, Kai Sun, Jin-Shi Xu, Geng Chen, Jian-Shun Tang, Ming Gong, Yong-Jian Han, Chuan-Feng Li, and Guang-Can Guo We report the experimental measurement of the winding number in an unitary chiral quantum walk. Fundamentally, the spin-orbit coupling in discrete time quantum walks is implemented via a birefringent crystal collinearly cut based on a time-multiplexing scheme. Our protocol is compact and avoids extr... [Phys. Rev. Lett. 120, 260501] Published Tue Jun 26, 2018
    Keywords: General Physics: Statistical and Quantum Mechanics, Quantum Information, etc.
    Print ISSN: 0031-9007
    Electronic ISSN: 1079-7114
    Topics: Physics
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  • 3
    Publication Date: 2018-12-19
    Description: Author(s): Wei Sun, Chang-Rui Yi, Bao-Zong Wang, Wei-Wei Zhang, Barry C. Sanders, Xiao-Tian Xu, Zong-Yao Wang, Joerg Schmiedmayer, Youjin Deng, Xiong-Jun Liu, Shuai Chen, and Jian-Wei Pan Topological quantum states are characterized by nonlocal invariants. We present a new dynamical approach for ultracold-atom systems to uncover their band topology, and we provide solid evidence to demonstrate its experimental advantages. After quenching a two-dimensional (2D) Chern band, realized in... [Phys. Rev. Lett. 121, 250403] Published Tue Dec 18, 2018
    Keywords: General Physics: Statistical and Quantum Mechanics, Quantum Information, etc.
    Print ISSN: 0031-9007
    Electronic ISSN: 1079-7114
    Topics: Physics
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