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  • Key words:  In situ hybridization assay  (1)
  • Keywords Controllability, Singular perturbation, Heat equation, Wave equation  (1)
  • Springer  (2)
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  • Springer  (2)
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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Acta mathematica sinica 16 (2000), S. 601-612 
    ISSN: 1000-9574
    Keywords: Keywords Controllability, Singular perturbation, Heat equation, Wave equation ; 1991MR Subject Classification 93B05, 93B07, 93D15
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mathematics
    Notes: Abstract In this note we analyze the exact controllability of singularly perturbed damped wave equations under more general geometric control condition than that of [1]. We show that the null controllability of the heat equation can be obtained as a singular limit of the exact controllability of such sorts of wave equations.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1432-198X
    Keywords: Key words:  In situ hybridization assay ; Hepatitis B virus DNA ; Hepatitis B virus antigen ; Hepatitis B virus-associated glomerulonephritis ; Cytokines
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract. Renal tissues from 43 of 49 children with hepatitis B virus-associated glomerulonephritis (HBV-GN) were examined for HBV DNA by in situ hybridization (ISH) assay within the last 10 years. HBV DNA was identified in 41 of the 43 cases (95.3%). HBV DNA was distributed generally in the nucleus and cytoplasm of epithelial cells and mesangial cells of glomeruli, and epithelial cells of renal tubules. HBV DNA also existed simultaneously in renal interstitial tissues in some of these cases. The positive results from HBV DNA ISH correlated well with HBV antigen assays. The analyses implied that the more extensive the existence of HBV DNA in the nephron unit and interstitial tissue, the more severe the clinical manifestation. The duration of proteinuria in cases with HBV DNA in renal tubules was much longer than in those with no HBV DNA in renal tubules. The persistence of the HBV genome or genes in the kidney could lead to the expression of viral antigens in renal tissues and might cause cellular pathological alteration. This would support utilization of antiviral therapy, such as cytokines, in the treatment of HBV-GN.
    Type of Medium: Electronic Resource
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