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  • Nature Publishing Group  (7)
  • MDPI Publishing  (2)
  • Copernicus Publications on behalf of the European Geosciences Union  (1)
  • 1
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature 437 (2005), S. 1326-1329 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Images of Saturn's narrow and contorted F ring returned by the Cassini spacecraft have revealed phenomena not previously detected in any planetary ring system. The perturbing effect of the inner shepherding satellite, Prometheus, seems to introduce channels through the F ring and a ...
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature biotechnology 23 (2005), S. 1303-1307 
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Chemical genomics aims to discover small molecules that affect biological processes through the perturbation of protein function. However, determining the protein targets of bioactive compounds remains a formidable challenge. We address this problem here through the creation of a natural ...
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature 358 (1992), S. 520-521 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] RADIOACTIVELY-LABELLED nucleic acids are used extensively in molecular biology re-search and form the cornerstone of major techniques such as filter hybridization, in situ hybridization and DNA sequencing. Nucleoside triphosphates labelled with 32P, 33P, 35S and other radioisotopes are now ...
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature 356 (1992), S. 111-112 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] OF ALL families of ion channels, those activated by mechanical forces remain perhaps the most elusive. The difficulty has been that, unlike channels such as the sodium or acetylcholine receptor channels, there just are not very many of them about. More importantly, the molecular nature of the ...
    Type of Medium: Electronic Resource
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  • 5
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] The nervous system senses peripheral damage through nociceptive neurons that transmit a pain signal. TRPA1 is a member of the Transient Receptor Potential (TRP) family of ion channels and is expressed in nociceptive neurons. TRPA1 is activated by a variety of noxious stimuli, including cold ...
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature 440 (2006), S. 1120-1121 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Two principal uncertainties in predicting climate change are the net effect of water in the climate system and the way in which water will be redistributed over the surface of the planet. On page 1179 of this issue, Treydte et al. present a reconstruction of precipitation in central Asia for ...
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  • 7
    Publication Date: 2017-07-21
    Description: Reproducible climate reconstructions of the Common Era (1 CE to present) are key to placing industrial-era warming into the context of natural climatic variability. Here we present a community-sourced database of temperature-sensitive proxy records from the PAGES2k initiative. The database gathers 692 records from 648 locations, including all continental regions and major ocean basins. The records are from trees, ice, sediment, corals, speleothems, documentary evidence, and other archives. They range in length from 50 to 2000 years, with a median of 547 years, while temporal resolution ranges from biweekly to centennial. Nearly half of the proxy time series are significantly correlated with HadCRUT4.2 surface temperature over the period 1850–2014. Global temperature composites show a remarkable degree of coherence between high- and low-resolution archives, with broadly similar patterns across archive types, terrestrial versus marine locations, and screening criteria. The database is suited to investigations of global and regional temperature variability over the Common Era, and is shared in the Linked Paleo Data (LiPD) format, including serializations in Matlab, R and Python.
    Repository Name: EPIC Alfred Wegener Institut
    Type: Article , isiRev
    Format: application/pdf
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  • 8
    Publication Date: 2022-05-25
    Description: © The Author(s), 2013. This article is distributed under the terms of the Creative Commons Attribution License. The definitive version was published in Climate of the Past 9 (2013): 1481-1493, doi:10.5194/cp-9-1481-2013.
    Description: We present a Bayesian model for estimating the parameters of the VS-Lite forward model of tree-ring width for a particular chronology and its local climatology. The scheme also provides information about the uncertainty of the parameter estimates, as well as the model error in representing the observed proxy time series. By inferring VS-Lite's parameters independently for synthetically generated ring-width series at several hundred sites across the United States, we show that the algorithm is skillful. We also infer optimal parameter values for modeling observed ring-width data at the same network of sites. The estimated parameter values covary in physical space, and their locations in multidimensional parameter space provide insight into the dominant climatic controls on modeled tree-ring growth at each site as well as the stability of those controls. The estimation procedure is useful for forward and inverse modeling studies using VS-Lite to quantify the full range of model uncertainty stemming from its parameterization.
    Description: This work was supported in part by an American Association of University Women Dissertation Fellowship and grants NSF ATM-0724802, NSF ATM-0902715, NSF DMS- 1204892, and NOAA NA060OAR4310115.
    Repository Name: Woods Hole Open Access Server
    Type: Article
    Format: application/zip
    Format: application/pdf
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  • 9
    Publication Date: 2017-03-12
    Description: Volunteer geographical information (VGI), either in the context of citizen science or the mining of social media, has proven to be useful in various domains including natural hazards, health status, disease epidemics, and biological monitoring. Nonetheless, the variable or unknown data quality due to crowdsourcing settings are still an obstacle for fully integrating these data sources in environmental studies and potentially in policy making. The data curation process, in which a quality assurance (QA) is needed, is often driven by the direct usability of the data collected within a data conflation process or data fusion (DCDF), combining the crowdsourced data into one view, using potentially other data sources as well. Looking at current practices in VGI data quality and using two examples, namely land cover validation and inundation extent estimation, this paper discusses the close links between QA and DCDF. It aims to help in deciding whether a disentanglement can be possible, whether beneficial or not, in understanding the data curation process with respect to its methodology for future usage of crowdsourced data. Analysing situations throughout the data curation process where and when entanglement between QA and DCDF occur, the paper explores the various facets of VGI data capture, as well as data quality assessment and purposes. Far from rejecting the usability ISO quality criterion, the paper advocates for a decoupling of the QA process and the DCDF step as much as possible while still integrating them within an approach analogous to a Bayesian paradigm.
    Electronic ISSN: 2220-9964
    Topics: Architecture, Civil Engineering, Surveying , Geosciences
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  • 10
    Publication Date: 2017-12-23
    Description: IJERPH, Vol. 15, Pages 11: Evaluation of Behavior Change Communication Campaigns to Promote Modern Cookstove Purchase and Use in Lower Middle Income Countries International Journal of Environmental Research and Public Health doi: 10.3390/ijerph15010011 Authors: William Evans Michael Johnson Kirstie Jagoe Dana Charron Bonnie Young A. Rahman Daniel Omolloh Julie Ipe Nearly three billion people worldwide burn solid fuels and kerosene in open fires and inefficient stoves to cook, light, and heat their homes. Cleaner-burning stoves reduce emissions and can have positive health, climate, and women’s empowerment benefits. This article reports on the protocol and baseline data from the evaluation of four behavior change communication (BCC) campaigns carried out in lower to middle income countries aimed at promoting the sale and use of cleaner-burning stoves. Interventions implemented in Bangladesh, Kenya, and Nigeria are using a range of BCC methods including mass media, digital media, outdoor advertising, and inter-personal communication. The mixed methods evaluation comprises three large-scale surveys: one pre-BCC and two follow-ups, along with smaller scale assessments of stove uptake and patterns of use. Baseline results revealed varying levels of awareness of previous promotions and positive attitudes and beliefs about modern (i.e., relatively clean-burning) cookstoves. Differences in cookstove preferences and behaviors by gender, socio-demographics, media use, and country/region were observed that may affect outcomes. Across all three countries, cost (lack of funds) a key perceived barrier to buying a cleaner-burning stove. Future multivariate analyses will examine potential dose-response effects of BCC on cookstove uptake and patterns of use. BCC campaigns have the potential to promote modern cookstoves at scale. More research on campaign effectiveness is needed, and on how to optimize messages and channels. This evaluation builds on a limited evidence base in the field.
    Print ISSN: 1661-7827
    Electronic ISSN: 1660-4601
    Topics: Energy, Environment Protection, Nuclear Power Engineering , Medicine
    Published by MDPI Publishing
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