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  • 1
    Electronic Resource
    Electronic Resource
    Effects of CuO Content on the Wetting Behavior and Mechanical Properties of a Ag–CuO Braze for Ceramic Joining (2005)
    Oxford, UK : Blackwell Science Inc
    Journal of the American Ceramic Society 88 (2005), S. 0 
    Details
    ISSN: 1551-2916
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: A silver-based joining technique referred to as reactive air brazing has been recently developed for joining high-temperature structural ceramic components of the type used in gas turbines, combustion engines, heat exchangers, and burners. It was found that additions of copper oxide to silver exhibit a tremendous effect on both the wettability and joint strength characteristics of the subsequent braze relative to polycrystalline alumina substrates. The effect is particularly significant at low copper oxide content, with substantial improvements in wetting observed in the 1–8 mol% range. The corresponding strength of the brazed polycrystalline alumina joints appears to be maximized at a copper oxide content of 8 mol%, with a maximum room temperature flexural strength approaching that of monolithic alumina. While further increases in oxide content lead to improved wetting on polycrystalline alumina, the effect on joint strength is deleterious. It appears that the formation of a continuous brittle copper-based oxide layer along the interface between the braze and alumina faying surface is responsible for the poor mechanical behavior observed in joints fabricated with higher copper oxide content brazes.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1551-2916.2005.00492.x
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  • 2
    Electronic Resource
    Electronic Resource
    Short-term effects of polynuclear aromatic hydrocarbons on sea-surface microlayer phytoneuston (1987)
    Springer
    Bulletin of environmental contamination and toxicology 38 (1987), S. 1037-1043 
    Details
    ISSN: 1432-0800
    Source: Springer Online Journal Archives 1860-2000
    Topics: Energy, Environment Protection, Nuclear Power Engineering , Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01609092
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  • 3
    Electronic Resource
    Electronic Resource
    A radiorespirometric method for evaluating inhibitors of sulphate-reducing bacteria (1983)
    Springer
    Applied microbiology and biotechnology 17 (1983), S. 49-52 
    Details
    ISSN: 1432-0614
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Summary A relatively simple, rapid and sensitive technique developed for measuring respiration of the sulphate-reducing bacteria which utilises a paper wick saturated with zinc acetate to trap 35S-sulphide produced by the bacteria from 35S-sulphate, has been adapted to compare the efficiencies of inhibitors of sulphate-reducing bacteria. The method was used to compare a glutaraldehyde-based, a formaldehydebased and a quaternary-ammonium compound (q.a.c.)-based inhibitor against a North Sea strain of sulphate-reducing bacteria. The results indicated that with a contact time of 1–2 h, and under the test conditions, 100 ppm of the glutaraldehyde and the q.a.c.-based inhibitors would be more effective inhibitors of this sulphate-reducing bacterium than would 100 ppm of the formaldehyde-based inhibitor. The method can be used to assess inhibitor efficiency and yield results in as little as 6 h.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00510571
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  • 4
    Electronic Resource
    Electronic Resource
    Association between coding variability in the LRP gene and the risk of late-onset Alzheimer’s disease (1999)
    Springer
    Human genetics 〈Berlin〉 104 (1999), S. 432-434 
    Details
    ISSN: 1432-1203
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract We have sequenced the entire (89 exons) open reading frame of the LRP gene in 12 cases of Alzheimer’s disease (AD) from Northern France. We have found no novel changes but confirm the occurrence of a polymorphism in exon 6 of the gene (A216V). This polymorphism is rare (2.8% of controls) and is in linkage equilibrium with previously reported polymorphisms. The V216 allele is negatively associated with the disease in a large case-controlled series. These data suggest that the LRP receptor may be involved in the pathobiology of AD, but the association that we report here cannot explain the previously reported genetic data implicating the LRP gene in AD. If the LRP gene is a major site of genetic variability leading to AD, there must be other biologically relevant variability in promoter or other regulatory elements of this large gene.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s004390050980
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  • 5
    Electronic Resource
    Electronic Resource
    Antigens similar to major histocompatibility complex B-G are expressed in the intestinal epithelium in the chicken (1990)
    Springer
    Immunogenetics 32 (1990), S. 45-50 
    Details
    ISSN: 1432-1211
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract A monoclonal antibody directed against the erythrocytic B-G antigens of the major histocompatibility complex (MHC) of the chicken, an antiserum raised against purified erythrocytic B-G protein, and a cDNA probe from the BeckmanB-G subregion were used to look for evidence of the expression ofB-G genes in tissues other than blood. Evidence has been found in northern hybridizations, in immunoblots, and in immunolabeled cryosections for the presence of B-G-like antigens in the duodenal and caecal epithelia. Additional B-G-like molecules may be expressed in the liver as well. The BG-like molecules in these tissues appear larger and somewhat more heterogeneous than the B-G antigens expressed on erythrocytes. Further characterization of these newly recognized B-G-like molecules may help to define a function for the enigmatic B-G antigens of the MHC. al. 1977; Miller et al. 1982, 1984; Salomonsen et al. 1987; Kline et al. 1988), and in the multiplicity of B-G restriction fragment patterns found in genomic DNA from different haplotypes (Goto et al. 1988; Miller et al. 1988; Chaussé et al. 1989). The B-G antigens have contributed, together with the B-F (class I) and B-L (class II) antigens, to the definition of over 27 B system haplotypes in experimental flocks (Briles et al. 1982). Yet the function of the B-G antigens remains entirely unknown. No mammalian counterparts have been identified, although the possibility remains that there may be similar antigens among the blood group systems of mammals. In an effort to define a function of the B-G antigens, a recently cloned B-G sequence (Miller et al. 1988; Goto et al. 1988) and antibodies to the B-G polypeptides (Miller et al. 1982, 1984) were used to examine other tissues for evidence of B-G expression.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01787328
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  • 6
    Electronic Resource
    Electronic Resource
    Beta-2-adrenoceptor agonists as inhibitors of lung vascular permeability to radiolabelled transferrin in the adult respiratory distress syndrome in man (1986)
    Springer
    European journal of nuclear medicine 12 (1986), S. 381-384 
    Details
    ISSN: 1619-7089
    Keywords: Respiratory distress syndrome, adult ; Beta-adrenoceptor agonist ; Vascular permeability ; Radio-labelled transferrin
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Increased lung vascular permeability leading to increased plasma protein extravasation and accumulation (PPA) is a characteristic feature of acute lung injury. Using a previously described technique, PPA was monitored in the lungs of patients with the adult respiratory distress syndrome (ARDS) — an extreme example of acute lung injury in man. An external radiation probe detector was used to monitor the pulmonary accumulation of the plasma protein transferrin radiolabelled in-vivo with 113mIn. Ten patients with ARDS exhibiting increased PPA indices (〉1.0x10-3/min) were given an intravenous infusion of terbutaline (7 μg/kg) over 30 min. Of the four patients in whom the post-drug PPA indices remained within the ARDS range, none survived, whilst five of the six patients in whom the post-drug PPA indices were reduced to below 1.0x10-3/min survived. PPA indices prior to the administration of terbutaline were not significantly different between the survivor (n=5) and non-survivor (n=5) groups. There was a significant decrease in the PPA indices following terbutaline in survivors (p〈0.01) but not in non-survivors. Thus beta-2-agonists in therapeutic doses can inhibit increased lung vascular permeability in man. These findings may have prognostic and therapeutic implication for beta-2-agonists in ARDS.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00252194
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  • 7
    Electronic Resource
    Electronic Resource
    Whole-bowel transit in patients with the irritable bowel syndrome (1986)
    Springer
    European journal of nuclear medicine 11 (1986), S. 393-396 
    Details
    ISSN: 1619-7089
    Keywords: Irritable bowel syndrome ; Whole-bowel transit
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The transit of radiolabelled preparations through the stomach, small intestine and colon was monitored in ten patients with the irritable bowel syndrome. Five patients complained of diarrhoea, and five complained of constipation. The preparations comprised a non-disintegrating capsule and a multiparticulate system. Both preparations emptied from the stomach together and at the same rates in both groups of patients. In the patients complaining of constipation, the transit times through the small intestine were the same for both preparations. In the patients complaining of diarrhoea, the capsule passed through the small intestine slightly faster than the particles, but there were no significant differences in the small-intestinal transit rates of the two patient groups. Within the colon, the transit of the capsule was faster than that of the small particles. Although movement through the colon was, on average, faster in the group of patients complaining of diarrhoea, there was considerable intersubject variability, and the differences in transit rates between the two patient groups were not statistically significant.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00261403
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  • 8
    Electronic Resource
    Electronic Resource
    Colonic motility and enema spreading (1986)
    Springer
    European journal of nuclear medicine 12 (1986), S. 176-178 
    Details
    ISSN: 1619-7089
    Keywords: Colon ; Enema ; Motility
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Radiolabelled enema solution was administered to eight healthy subjects, both in fasted and fed states. Enema spreading was monitored over a 4-h period using gamma scintigraphy and colonic motility was recorded simultaneously using a pressure sensitive radiotelemetry capsule. The rate and extent of enema dispersion were unaffected by eating. Spreading could be correlated with colonic motility and was inhibited by aboral propulsion of the colonic contents.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00256916
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  • 9
    Electronic Resource
    Electronic Resource
    Non-invasive investigation of lower limb revascularisation using resting thallium peripheral perfusion imaging (1986)
    Springer
    European journal of nuclear medicine 12 (1986), S. 443-446 
    Details
    ISSN: 1619-7089
    Keywords: 201Tl-thallous chloride ; Peripheral perfusion imaging ; Peripheral vascular disease
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Resting thallium thigh and calf imaging was performed in 11 patients with lower limb ischaemia before and after revascularisation. Eight patients had successful revascularisation but in the other three the procedure failed to improve the circulation. Despite symptomatic improvement and increases in ankle systolic pressures after successful revascularisation there was no change in thallium uptake. Thallium imaging was compared with radionuclide angiography and blood pool imaging in six patients. Radionuclide angiograms confirmed the presence of well developed collateral circulation in some patients with increased thallium uptake in the symptomatic limb and in all cases the angiograms were clinically useful. There was no correlation between thallium and blood pool images. Resting lower limb blood flow did not change after revascularisation and thallium peripheral perfusion imaging did not aid the assessment of the response to lower limb revascularisation.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00254748
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  • 10
    Electronic Resource
    Electronic Resource
    Serial radionuclide imaging during treatment of patients with diffuse bone metastases from carcinoma of the prostate (1982)
    Springer
    European journal of nuclear medicine 7 (1982), S. 322-323 
    Details
    ISSN: 1619-7089
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Follow-up studies have been undertaken on patients with carcinoma of the prostate who, prior to treatment, exhibited uniformly increased bone uptake of 99mTclabelled methylene diphosphonate. In general, therapy led to a reduction in the degree of radiopharmaceutical uptake on follow-up. In some cases the radionuclide bone images retained their uniform appearances, whilst in others a patchy uptake developed, more characteristic of metastatic deposits. Radiographically the changes were less pronounced than those seen in the radionuclide studies.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00253429
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