GLORIA

GEOMAR Library Ocean Research Information Access

feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
  • 1
    Publication Date: 2022-05-25
    Description: Author Posting. © American Meteorological Society, 2011. This article is posted here by permission of American Meteorological Society for personal use, not for redistribution. The definitive version was published in Journal of Physical Oceanography 41 (2011): 889–910, doi:10.1175/2010JPO4496.1.
    Description: This paper examines interaction between a barotropic point vortex and a steplike topography with a bay-shaped shelf. The interaction is governed by two mechanisms: propagation of topographic Rossby waves and advection by the forcing vortex. Topographic waves are supported by the potential vorticity (PV) jump across the topography and propagate along the step only in one direction, having higher PV on the right. Near one side boundary of the bay, which is in the wave propagation direction and has a narrow shelf, waves are blocked by the boundary, inducing strong out-of-bay transport in the form of detached crests. The wave–boundary interaction as well as out-of-bay transport is strengthened as the minimum shelf width is decreased. The two control mechanisms are related differently in anticyclone- and cyclone-induced interactions. In anticyclone-induced interactions, the PV front deformations are moved in opposite directions by the point vortex and topographic waves; a topographic cyclone forms out of the balance between the two opposing mechanisms and is advected by the forcing vortex into the deep ocean. In cyclone-induced interactions, the PV front deformations are moved in the same direction by the two mechanisms; a topographic cyclone forms out of the wave–boundary interaction but is confined to the coast. Therefore, anticyclonic vortices are more capable of driving water off the topography. The anticyclone-induced transport is enhanced for smaller vortex–step distance or smaller topography when the vortex advection is relatively strong compared to the wave propagation mechanism.
    Description: Y. Zhang acknowledges the support of theMIT-WHOI Joint Programin Physical Oceanography, NSF OCE-9901654 and OCE-0451086. J. Pedlosky acknowledges the support of NSF OCE- 9901654 and OCE-0451086.
    Keywords: Transport ; Eddies ; Barotropic flow ; Topographic effects ; Vortices ; Currents ; Potential vorticity ; Rossby waves
    Repository Name: Woods Hole Open Access Server
    Type: Article
    Format: application/pdf
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
  • 2
    facet.materialart.
    Unknown
    American Meteorological Society
    Publication Date: 2022-05-25
    Description: Author Posting. © American Meteorological Society, 2007. This article is posted here by permission of American Meteorological Society for personal use, not for redistribution. The definitive version was published in Journal of Physical Oceanography 37 (2007): 2158–2171, doi:10.1175/jpo3100.1.
    Description: The triad instability of the large-scale, first-mode, baroclinic Rossby waves is studied in the context of the planetary scale when the Coriolis parameter is to its lowest order varying with latitude. Accordingly, rather than remain constant as in quasigeostrophic theory, the deformation radius also changes with latitude, yielding new and interesting features to the propagation and triad instability processes. On the planetary scale, baroclinic waves vary their meridional wavenumbers along group velocity rays while they conserve both frequencies and zonal wavenumbers. The amplitudes of both barotropic and baroclinic waves would change with latitude along a ray path in the same way that the Coriolis parameter does if effects of the nonlinear interaction are ignored. The triad interaction for a specific triad is localized within a small latitudinal band where the resonance conditions are satisfied and quasigeostrophic theory is applicable locally. Using the growth rate from that theory as a measure, at each latitude along the ray path of the basic wave, a barotropic wave and a secondary baroclinic wave are picked up to form the most unstable triad and the distribution of this maximum growth rate is examined. It is found to increase southward under the assumption that triad interactions do not cause a noticeable decrease in the quantity of the basic wave’s amplitude divided by the Coriolis parameter. Different barotropic waves that maximize the growth rate at different latitudes have almost the same meridional length scale, on the order of the deformation radius. With many rays starting from different latitudes on the eastern boundary and with wavenumbers on each of them satisfying the no-normal-flow condition, the resulting two-dimensional distribution of the growth rate is a complicated function of the relative relations of zonal wavenumbers or frequencies on different rays and the orientation of the eastern boundary. In general, the growth rate is largest on rays originating to the north.
    Description: This research was supported in part by NSF OCE 0451086 and by the MIT/WHOI Joint Program in Physical Oceanography.
    Keywords: Rossby waves ; Planetary waves ; Waves, oceanic
    Repository Name: Woods Hole Open Access Server
    Type: Article
    Format: application/pdf
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
  • 3
    Publication Date: 2022-05-25
    Description: Author Posting. © American Meteorological Society, 2011. This article is posted here by permission of American Meteorological Society for personal use, not for redistribution. The definitive version was published in Journal of Physical Oceanography 41 (2011): 2168–2186, doi:10.1175/JPO-D-11-08.1.
    Description: This paper studies the interaction of an Antarctic Circumpolar Current (ACC)–like wind-driven channel flow with a continental slope and a flat-bottomed bay-shaped shelf near the channel’s southern boundary. Interaction between the model ACC and the topography in the second layer induces local changes of the potential vorticity (PV) flux, which further causes the formation of a first-layer PV front near the base of the topography. Located between the ACC and the first-layer slope, the newly formed PV front is constantly perturbed by the ACC and in turn forces the first-layer slope with its own variability in an intermittent but persistent way. The volume transport of the slope water across the first-layer slope edge is mostly directly driven by eddies and meanders of the new front, and its magnitude is similar to the maximum Ekman transport in the channel. Near the bay’s opening, the effect of the topographic waves, excited by offshore variability, dominates the cross-isobath exchange and induces a mean clockwise shelf circulation. The waves’ propagation is only toward the west and tends to be blocked by the bay’s western boundary in the narrow-shelf region. The ensuing wave–coast interaction amplifies the wave amplitude and the cross-shelf transport. Because the interaction only occurs near the western boundary, the shelf water in the west of the bay is more readily carried offshore than that in the east and the mean shelf circulation is also intensified along the bay’s western boundary.
    Description: Y. Zhang acknowledges the support of the MIT-WHOI Joint Program in Physical Oceanography and NSF OCE-9901654 and OCE- 0451086. J. Pedlosky acknowledges the support of NSF OCE-9901654 and OCE-0451086.
    Keywords: Baroclinic flows ; Eddies ; Fronts ; Mass fluxes/transport ; Mesoscale processes ; Topographic effects
    Repository Name: Woods Hole Open Access Server
    Type: Article
    Format: application/pdf
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
  • 4
    facet.materialart.
    Unknown
    American Meteorological Society
    Publication Date: 2022-06-06
    Description: Author Posting. © American Meteorological Society, 2021. This article is posted here by permission of American Meteorological Society for personal use, not for redistribution. The definitive version was published in Journal of Physical Oceanography 51(12),(2021): 3651–3662, https://doi.org/10.1175/JPO-D-21-0076.1.
    Description: Ocean striations are composed of alternating quasi-zonal band-like flows; this kind of organized structure of currents can be found in all the world’s oceans and seas. Previous studies have mainly been focused on the mechanisms of their generation and propagation. This study uses the spatial high-pass filtering to obtain the three-dimensional structure of ocean striations in the North Pacific in both the z coordinate and σ coordinate based on 10-yr averaged Simple Ocean Data Assimilation version 3 (SODA3) data. First, we identify an ideal-fluid potential density domain where the striations are undisturbed by the surface forcing and boundary effects. Second, using the isopycnal layer analysis, we show that on isopycnal surfaces the orientations of striations nearly follow the potential vorticity (PV) contours, while in the meridional–vertical plane the central positions of striations are generally aligned with the latitude of zero gradient of the relative PV. Our analysis provides a simple dynamical interpretation and better understanding for the role of ocean striations.
    Description: This work is supported by the National Natural Science Foundation of China (42076025, 41676021), the Key Special Project for introduced Talents Team of Southern Marine Science and Engineering Guangdong Laboratory (Guangzhou) (GML2019ZD0306), the National Basic Research Program (973 Program) of China (2013CB956201). The numerical simulation is supported by the High Performance Computing Division in the South China Sea Institute of Oceanography. The authors thank Tingjin Guan for the help in enhancing drawing quality.
    Keywords: Currents ; Jets ; Mesoscale processes ; Potential vorticity ; Isopycnal coordinates
    Repository Name: Woods Hole Open Access Server
    Type: Article
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
  • 5
    Publication Date: 2018-01-25
    Description: Objective—Intermedin plays an important role in vascular remodeling and significantly improves blood perfusion, but the precise mechanism remains unclear. Herein, we aimed to define whether vascular lumen enlargement is responsible for the intermedin-increased blood perfusion and explore the underlying cellular and molecular mechanisms.Approach and Results—To study the role of intermedin, we generated the IMD-KO (Adm2−/−) mice using CRISPR/Cas9 (clustered regularly interspaced short palindromic repeats/clustered regularly interspaced short palindromic repeat–associated 9) system. Intermedin significantly promoted vascular lumen enlargement in vitro (fibrin beads assay) and in vivo (murine retinas), which contributed to the improved blood perfusion in both physiological (retinal) and pathological (tumor) angiogenic models. We designed experiments to calculate the endothelial cell (EC) size and found that the lumen enlargement is because of EC proliferation but not because of a change in cell shape. ECs that construct vessel walls are considered quiescent cells because they are in a state of contact inhibition and show reduced responsiveness to VEGF (vascular endothelial growth factor). Using immunoprecipitation, Western blot assay, and fluorescent microscopy, we found that intermedin induced the formation of a signaling complex containing CRLR (calcitonin receptor-like receptor)/β-arr1 (β-arrestin1)/Src in ECs and promoted it internalizing into cytoplasm in a clathrin-dependent manner to activate downstream ERK1/2 (extracellular signal-regulated kinase 1/2). Importantly, this effect was not abrogated by cell–cell contacts of ECs. Through this mechanism, intermedin could reactivate the quiescent ECs to proliferate, resulting in continuous lumen expanding and a more effective blood perfusion.Conclusions—Our findings suggest a novel mechanism that may explain how quiescent ECs overcome the contact inhibition and regain the ability to proliferate for continuous vascular lumen enlargement.
    Keywords: Angiogenesis
    Print ISSN: 1079-5642
    Electronic ISSN: 1524-4636
    Topics: Medicine
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
  • 6
    Publication Date: 2017-09-14
    Description: The longitudinal exposure–response relationship between trimester-specific gestational weight gain (GWG) and blood pressure (BP) during pregnancy is not well understood. We retrospectively assessed 1112 uncomplicated, normotensive pregnant women whose body weight and BP were measured from 12+0 to 40+0 weeks of gestation from a hospital-based cohort. By using growth curve modeling, a J-shaped pattern dominated diastolic BP (DBP) changing dynamics, with a midpregnancy drop at 20+0 to 22+0 weeks followed by a rebound. Using group-based trajectory modeling, 3 distinctive trajectories of DBP were identified: high–J shaped (18.5%), moderate–J shaped (48.3%), and low–J shaped (33.1%), as well as 3 distinctive GWG trajectories: high increasing (14.7%), moderate increasing (48.6%) and low increasing (36.8%). A temporal coincidence between the maximal rate of GWG and DBP transition from its nadir to rebound was observed during 20+0 to 22+0 weeks. Moreover, women in the high-increasing GWG group had the highest probability of being in the high–J DBP group. The GWG rate during the late midsecond trimester (22+0 to 26+0 weeks) was consistently associated with an elevated DBP level: for every 200 g/wk increase, the multivariable-adjusted odds ratio was 1.27 (95% confidence interval, 1.13–1.43) for the trajectory shift to the high–J group and 1.20 (95% confidence interval, 1.07–1.35) for the occurrence of diastolic prehypertension after 37+0 weeks. Furthermore, adding a trimester-specific GWG rate (22+0 to 26+0 weeks) contributed to the incremental yield for the prediction of diastolic prehypertension after 37+0 weeks. Our results thus provide the timing and extent of gestational weight control relevant to the optimized BP level during pregnancy.
    Keywords: Clinical Studies, Mechanisms, Physiology, High Blood Pressure
    Print ISSN: 0194-911X
    Topics: Medicine
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
  • 7
    Publication Date: 2017-01-06
    Description: Rationale:Angiogenic hypersprouting and leaky vessels are essential for tumor growth. MicroRNAs have unique therapeutic advantages by targeting multiple pathways of tumor-associated angiogenesis, but the function of individual miRNAs of miR302-367 cluster in angiogenesis and tumors has not yet been fully evaluated.Objective:To investigate the functions of miR302-367 in developmental angiogenesis and tumor angiogenesis and explore the molecular mechanisms of microRNA for the treatment of pathological neovascularization-related diseases.Methods and Results:Here, we show that miR302-367 elevation in endothelial cells reduces retinal sprouting angiogenesis and promotes vascular stability in vivo, ex vivo, and in vitro. Erk1/2 is identified as direct target of miR302-367, and downregulation of Erk1/2 on miR302-367 elevation in endothelial cells increases the expression of Klf2 and in turn S1pr1 and its downstream target VE-cadherin, suppressing angiogenesis and improving vascular stability. Conversely, both pharmacological blockade and genetic deletion of S1pr1 in endothelial cells reverse the antiangiogenic and vascular stabilizing effect of miR302-367 in mice. Tumor angiogenesis shares features of developmental angiogenesis, and endothelial specific elevation of miR302-367 reduces tumor growth by restricting sprout angiogenesis and decreasing vascular permeability via the same Erk1/2-Klf2-S1pr1 pathways.Conclusions:MiR302-367 regulation of an Erk1/2-Klf2-S1pr1 pathway in the endothelium advances our understanding of angiogenesis, meanwhile also provides opportunities for therapeutic intervention of tumor growth.
    Keywords: Angiogenesis, Vascular Biology
    Print ISSN: 0009-7330
    Electronic ISSN: 1524-4571
    Topics: Medicine
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
  • 8
    Publication Date: 2017-04-25
    Description: Background and Purpose—Symptomatic intracranial hemorrhage (SICH) pose a major safety concern for endovascular treatment of acute ischemic stroke. This study aimed to evaluate the risk and related factors of SICH after endovascular treatment in a real-world practice.Methods—Patients with stroke treated with stent-like retrievers for recanalizing a blocked artery in anterior circulation were enrolled from 21 stroke centers in China. Intracranial hemorrhage was classified as symptomatic and asymptomatic ones according to Heidelberg Bleeding Classification. Logistic regression was used to identify predictors for SICH.Results—Of the 632 enrolled patients, 101 (16.0%) were diagnosed with SICH within 72 hours after endovascular treatment. Ninety-day mortality was higher in patients with SICH than in patients without SICH (65.3% versus 18.8%; P 0.83 (odds ratio [OR], 2.07; 95% confidence interval [CI], 1.24–3.46), pretreatment Alberta Stroke Program Early Computed Tomography Score of 270 minutes (OR, 1.70; 95% CI, 1.03–2.80), 〉3 passes with retriever (OR, 2.55; 95% CI, 1.40–4.65) were associated with SICH after endovascular treatment.Conclusions—Incidence of SICH after thrombectomy is higher in Asian patients with acute ischemic stroke. Cardioembolic stroke, poor collateral circulation, delayed endovascular treatment, multiple passes with stent retriever device, lower pretreatment Alberta Stroke Program Early Computed Tomography Score, higher baseline neutrophil ratio may increase the risk of SICH.
    Keywords: Intracranial Hemorrhage, Ischemic Stroke
    Print ISSN: 0039-2499
    Electronic ISSN: 1524-4628
    Topics: Medicine
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
  • 9
    Publication Date: 2017-04-13
    Description: Despite the inverse association between physical activity (PA) and incident hypertension, a comprehensive assessment of the quantitative dose–response association between PA and hypertension has not been reported. We performed a meta-analysis, including dose–response analysis, to quantitatively evaluate this association. We searched PubMed and Embase databases for articles published up to November 1, 2016. Random effects generalized least squares regression models were used to assess the quantitative association between PA and hypertension risk across studies. Restricted cubic splines were used to model the dose–response association. We identified 22 articles (29 studies) investigating the risk of hypertension with leisure-time PA or total PA, including 330 222 individuals and 67 698 incident cases of hypertension. The risk of hypertension was reduced by 6% (relative risk, 0.94; 95% confidence interval, 0.92–0.96) with each 10 metabolic equivalent of task h/wk increment of leisure-time PA. We found no evidence of a nonlinear dose–response association of PA and hypertension (Pnonlinearity=0.094 for leisure-time PA and 0.771 for total PA). With the linear cubic spline model, when compared with inactive individuals, for those who met the guidelines recommended minimum level of moderate PA (10 metabolic equivalent of task h/wk), the risk of hypertension was reduced by 6% (relative risk, 0.94; 95% confidence interval, 0.92–0.97). This meta-analysis suggests that additional benefits for hypertension prevention occur as the amount of PA increases.
    Keywords: Epidemiology, Exercise, Hypertension
    Print ISSN: 0194-911X
    Topics: Medicine
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...