Keywords:
Organofluorine compounds.
;
Electronic books.
Type of Medium:
Online Resource
Pages:
1 online resource (272 pages)
Edition:
1st ed.
ISBN:
9783540691976
Series Statement:
Topics in Current Chemistry Series ; v.193
URL:
https://ebookcentral.proquest.com/lib/geomar/detail.action?docID=6485842
DDC:
547.02
Language:
English
Note:
Intro -- 193Topics in Current Chemistry -- Organofluorine ChemistryTechniques and Synthons -- Volume Editor -- Editorial Board -- Preface -- Contents -- Contents of Volume 192Organofluorine Chemistry: Fluorinated Alkenesand Reactive Intermediates -- Elemental Fluorine in Organic Chemistry -- 1Introduction -- 2Perfluorination -- 2.1Mechanistic Considerations -- 2.2Hydrocarbons -- 2.3Haloalkanes -- 2.4Ethers and Polyethers -- 2.5Ketones, Esters and Related Compounds -- 2.6Substrates Containing Nitrogen, Sulfur or Phosphorous -- 2.7Carbon -- 3Selective Direct Fluorination -- 3.1Preparation of Carbon-Fluorine Bonds -- 3.1.1Replacement of Hydrogen by Fluorine -- 3.1.1.1 Alkanes -- 3.1.1.2Carbonyl Compounds -- 3.1.1.3Benzenoid Compounds -- 3.1.1.4Heterocyclic aromatic compounds -- 3.1.2Fluorodesulfurization ReactionsThe conversion of carbon-sulfur bonds -- 3.1.3Fluorodemetallisation -- 3.1.4 Addition of Elemental Fluorine to Carbon-Carbon Double Bonds -- 3.2Preparation of Oxygen-Fluorine Bonds. -- 3.2.1Perfluoroalkyl, Acyl and Perfluoroacyl Hypofluorites -- 3.2.2Alkyl Hypofluorites -- 3.3Preparation of Nitrogen-Fluorine Bonds -- 4 Fluorine as aReagent for the Synthesis ofNon-Fluorinated Compounds -- 4.1Organic Transformations Promoted by Fluorine -- 5References -- Fluorinated Organometallic Compounds -- 1 Introduction -- 2 Fluorinated Alkyl Organometallics -- 2.1Perfluoroalkyl Lithium Reagents -- 2.2Perfluoroalkyl Magnesium Reagents -- 2.3Perfluoroalkyl Zinc Reagents -- 2.4Perfluoroalkyl Copper Reagents -- 2.5Perfluoroalkyl Tin Reagents -- 3 Fluorinated Alkenyl Organometallics -- 3.1Fluorinated Alkenyl Lithium Reagents -- 3.2Fluorinated Alkenyl Zinc Reagents -- 3.3Fluorinated Alkenyl Copper Reagents -- 3.4Fluorinated Alkenyl Tin Reagents -- 4 Fluorinated Aryl Organometallics -- 4.1Perfluoroaryl Lithium Reagents -- 4.2Perfluoroaryl Magnesium Reagents.
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4.3Perfluoroaryl Copper Reagents -- 5Carboalkoxydifluoromethylene Organometallics -- 5.1Carboalkoxydifluoromethylene Zinc Reagent -- 5.2Carboalkoxydifluoromethylene Copper Reagent -- 6Dialkoxyphosphinydifluoromethyl Organometallics -- 6.1Dialkoxyphosphinydifluoromethyl Lithium Reagents -- 6.2Dialkoxyphosphinydifluoromethyl Cadmium Reagent -- 6.3Dialkoxyphosphinydifluoromethyl Zinc and Copper Reagent -- 7a,a-Difluoroallyl and a,a-Difluoropropargyl Organometallics -- 7.1a,a-Difluoroallyl Organometallics -- 7.2a,a-Difluoropropargyl Organometallics -- 8References -- Enzymatically Controlled Reactions of OrganofluorineCompounds -- 1Introduction -- 2Asymmetric Induction via the Reduction of a Carbonyl Group -- 3Lipase-catalyzed Asymmetric Induction -- 3.1Asymmetric Hydrolysis -- 3.2Determination of Absolute Configuration -- 3.3Diastereocontrolled Reaction -- 4Building Blocks derived from Microbial Transformation -- 4.1Epoxidation with Microorganisms -- 4.2Fluorinated Building Blocks for Sugar Derivatives -- 4.3Fluorinated Amino Acids -- 5Useful Reagents and Materials -- 6References -- Building Block Approaches to AliphaticOrganofluorine Compounds -- 1Introduction -- 2 One-Carbon Fluorinated Building Blocks -- 2.1Fluorohalomethanes as Carbene Precursors -- 2.2Fluorohalomethanes as Electrophiles -- 2.3Fluoromethane-derived Nucleophiles and Free Radicals -- 2.3.1Unstabilised Species -- 2.3.2Stabilised Species -- 3 Two-Carbon Fluorinated Building Blocks -- 3.1Halofluoroalkanes as Building Blocks -- 3.2Fluoroalkene Building Blocks -- 3.2.1Metallated Fluoroalkenes -- 3.2.2Miscellaneous Fluoroalkene Reactions -- 3.3Fluoroethanol Building Blocks -- 3.3Other Fluoroethyl Building blocks -- 3.4Fluorinated Acetaldehyde Derivatives -- 3.5Fluorinated Acetic Acid Derivatives -- 4 Three Carbon Fluorinated Building Blocks -- 4.1Trifluoropropene Derivatives.
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4.2Activated Trifluoropropene Derivatives -- 4.3g,g-Difluoroallylic Derivatives -- 4.4Fluoroacetone Derivatives -- 4.5Tetrafluoropropanol Derivatives -- 4.6Trifluoropyruvic Acid Derivatives -- 5 Four-Carbon Fluorinated Building Blocks -- 5.12-(Trifluoromethyl)propenoic Acid -- 5.2Ethyl 4,4,4-Trifluoro-2-butenoate and Related Compounds -- 5.3Ethyl 4,4,4-Trifluoro-3-oxobutanoate and Related Compounds -- 5.41,1,1-Trifluorobut-3-en-2-one and Related Compounds -- 6Larger Fluorinated Building Blocks -- 7 Transformations of Fluorinated Motifs -- 7.1Aldol and Related Reactions involving Fluoroenolates and Equivalents -- 7.2Transformations of Fluoroallylic Compounds -- 7.2.1g,g-Difluoroallylic Compounds -- 7.2.2b-Fluoroallylic Compounds -- 7.3Cycloaddition Reactions with Fluorinated Components -- 7.4Free Radical Reactions involving Fluorinated Centres -- 8Conclusions and Perspectives -- References -- Electrofluorination of Organic Compounds -- 1Introduction -- 2Electrolysis in Molten Fluoride Salts or Fluoride Ion Solutions -- 2.1Alkene Derivatives -- 2.2Aromatic Compounds -- 2.3Benzylic Compound -- 2.4Aldehydic Compounds -- 2.5Compounds Containing Hetero-Atoms -- 2.6Thioacetal Compounds -- 2.7Lignins -- 2.8Cyclic Ketones -- 3Electrolysis in Molten Potassium Fluoride/HydrogenFluoride at a Porous Anode -- 3.1Equipment -- 3.2Operational Complexities -- 3.3Synthetic Utility and Mechanism -- 4Electrolysis in Anhydrous Hydrogen Fluoride at Nickel Anodes -- 4.1Chemistry to Expand the Synthetic Scope of ECF -- 4.1.1Amines -- 4.1.2Amino-Ethers -- 4.1.3Nitrogen-Containing Carboxylic Acids -- 4.1.4Sulphur Compounds -- 4.1.5Ethers -- 4.1.6Volatile Fluorocarbons -- 4.2Techniques to Improve the Performance of ECF -- 4.2.1Reaction Parameters and Cell Design -- 4.2.2Electrolyte Additives -- 4.2.3Choice of Starting Material.
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4.2.4Electrochemical Engineering and Operational Procedures -- 4.2.5Anode Construction and Corrosion Management -- 4.3Attempts to Elucidate the Mechanism of ECF -- 4.3.1The Carbocation Mechanism -- 4.3.2The Radical Mechanism -- 5References -- Author Index Volumes 151 -1 93.
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