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  • 1
    Book
    Book
    Methods for the Assessment of Oil-Mineral Aggregates (2000)
    Details Availability
    Type of Medium: Book
    Pages: 40 S. , Ill., graph. Darst.
    ISBN: 0662292510
    Language: English
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  • 2
    Electronic Resource
    Electronic Resource
    Suppression of accelerated diabetic atherosclerosis by the soluble receptor for advanced glycation endproducts (1998)
    [s.l.] : Nature America Inc.
    Nature medicine 4 (1998), S. 1025-1031 
    Details
    ISSN: 1546-170X
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Medicine
    Notes: [Auszug] Accelerated atherosclerosis in patients with diabetes is a major cause of their morbidity and mortality, and it is unresponsive to therapy aimed at restoring relative euglycemia. In hyperglycemia, nonenzymatic glycation and oxidation of proteins and lipids results in the accumulation of ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/2012
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Myoelectric activity and absorptive capacity of rat small intestinal isografts (1996)
    Springer
    Digestive diseases and sciences 41 (1996), S. 1082-1087 
    Details
    ISSN: 1573-2568
    Keywords: small intestine ; transplantation ; gastrointestinal motility ; intestinal absorption
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The effect of transplantation on small intestinal absorption, digestive capacity, myoelectric activity, and morphology was assessed in inbred Lewis rats. Electrodes were sutured to the duodenum and isografted jejunoileum or to the native jejunoileum in controls. The frequency of migrating myoelectric complexes (MMCs) in the duodenum was 3.3±0.3/hr in controls and 1.8±0.4/hr in transplants (P〈0.05). MMC frequency in the jejunoileum was 5.1±1.3/hr in controls and 3.2±0.9/hr in transplants (P〉0.05). MMCs appeared to migrate from the duodenum to the jejunoileum 80±3% of the time in controls and 59±7% of the time in transplant rats (P〈0.05). Absorption in the transplanted jejunoileum demonstrated a 35–40% decrease in glucose and electrolytes absorption. Villus height and number of nuclei per villus was reduced. Intestinal length (dry) was 103±6 cm for controls and 51±3 cm for transplant rats (P〈0.05). Brush border sucrase activity was unchanged. We conclude that small intestinal isografts display similar myoelectric activity as controls, but the decreased absorptive capacity and villus height may require longer segments of intestine to be transplanted in order to support normal nutrition.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02088223
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Decreased mucosal IgA levels in ileum of patients with chronic ulcerative colitis (1995)
    Springer
    Digestive diseases and sciences 40 (1995), S. 805-811 
    Details
    ISSN: 1573-2568
    Keywords: immunoglobulin A ; ulcerative colitis ; ileum
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Patients with chronic ulcerative colitis (CUC) are known to have decreased spontaneous IgA secretion by colonic mononuclear cells. The aim of this study was to determine whether a similar alteration exists in the apparently healthy ileum of patients with CUC. The concentration of IgA was measured in the supernatant from homogenized mucosal ileal biopsies using a sandwich-type ELISA. The concentration of IgA was significantly (P=0.025) decreased in the ileum of patients with CUC (N=24) in comparison to normal ileum (N=10). The number of mucosal IgA-containing mononuclear cells (MNC) was also determined using an avidin-biotin-immunoperoxidase technique on paraffin-embedded ileal sections. Although reduced, the number of positive cells and their distribution was not significantly different in the ileum of patients with CUC (N=20) when compared to normal ileum (N=10). We suggest that decreased mucosal IgA levels are a panintestinal condition in CUC and that this is a primary alteration rather than a secondary response to the inflammatory process. Considering the role of IgA, we propose that decreased mucosal IgA levels in CUC may predispose to the disease by a reduction of the immune-mediated exclusion mechanism and/or by an impairment of the down-regulation of the inflammatory response.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02064983
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  • 5
    Electronic Resource
    Electronic Resource
    Modeling the Transport of Contaminants Originating from the Dissolution of DNAPL Pools in Aquifers in the Presence of Dissolved Humic Substances (2000)
    Springer
    Transport in porous media 38 (2000), S. 93-115 
    Details
    ISSN: 1573-1634
    Keywords: contaminant transport ; transport of humic substances ; NAPL pool dissolution ; dissolved organic carbon ; aquifer remediation ; numerical modeling
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences , Technology
    Notes: Abstract A two‐dimensional finite difference numerical model was developed to describe the transport of dissolved organics originating from nonaqueous phase liquid (NAPL) pool dissolution in saturated porous media in the presence of dissolved humic substances. A rectangular NAPL pool was considered in a homogeneous porous medium with unidirectional interstitial groundwater velocity. It was assumed that dissolved humic substances and aqueous phase contaminants may sorb onto the solid matrix under local equilibrium conditions. The contaminant in the aqueous phase may undergo first‐order decay. Also, the dissolved contaminant may sorb onto humic substances. The transport properties of dissolved humic substances are assumed to be unaffected by sorbing contaminants, because dissolved humic macromolecules are much larger than dissolved contaminants and sorption of nonpolar contaminants onto humic substances do not affect the overall surface charge of humic substances. The sorption characteristics of dissolved humic substances onto clean sand were determined from column experiments. An effective local mass transfer rate coefficient accounting for the presence of dissolved humic substances was developed. Model simulations indicate that dissolved humic substances substantially increase NAPL pool dissolution, and consequently reduce the required pump‐and‐treat aquifer remediation time.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1006674114600
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    Paper (German National Licenses)
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