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  • 2010-2014  (85)
  • 2005-2009  (11)
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  • 1
    Online Resource
    Online Resource
    Amsterdam :IOS Press, Incorporated,
    Keywords: Electronic books.
    Description / Table of Contents: Coronary disease is the number one cause of death in the United States and the Western world and approximately 250,000 affected people die per year without being admitted to the hospital. One of the main reasons of such a high death rate without any diagnostics in more than 50% of myocardial infarctions (MIs or heart attacks) occur in patients with no prior history of heart attack disease or symptoms. Coronary artery disease leads to the occlusion of arteries that are vital in providing nutrients to the heart muscles. The disease develops by progressive accumulation or formation of 'plaque' within an artery. Certain types of arteries could occlude blood flow and yet might be 'stable'. These plaques usually have high fibrous content and are known as hard plaques. On the other hand, 'unstable or soft plaques' might not cause much occlusion but could be venerable to rupture. Rupture of such plaques could lead to total or partial occlusion in arteries resulting in sudden cardiac death or heart attack. In fact, 68% of the MIs are caused by rupture of plaques when coronary arteries are less than 50% occluded. This book is about plaque imaging covering both clinical and imaging aspects of plaque using Magnetic Resonance (MR), Computer Tomography (CT), Intravascular Ultrasound (IVUS), Elastography and at Molecular/Microscopic levels.
    Type of Medium: Online Resource
    Pages: 1 online resource (488 pages)
    Edition: 1st ed.
    ISBN: 9781607501169
    Series Statement: Studies in Health Technology and Informatics Series ; v.113
    Language: English
    Note: Title page -- Preface -- The Editors -- Acknowledgements -- The Contributors -- Contents -- Plaque Imaging Using Ultrasound, Magnetic Resonance and Computer Tomography: A Review -- Medical Image Retrieval Based on Plaque Appearance and Image Registration -- MRI Plaque Tissue Characterization and Assessment of Plaque Stability -- Intravascular Ultrasound Elastography: A Clinician's Tool for Assessing Vulnerability and Material Composition of Plaques -- Computer Vision Analysis of Collagen Fiber Bundles in the Adventitia of Human Blood Vessels -- Image Based Biomechanics of Coronary Plaque -- Computed Tomographic Cardiovascular Imaging -- Tomographic Plaque Imaging with CT -- Absolute Measurement of Integrated Backscatter from Arterial Wall Structures -- Ultrasound Imaging in the Analysis of Carotid Plaque Morphology for the Assessment of Stroke -- On the Assessment of Texture Feature Descriptors in Intravascular Ultrasound Images: A Boosting Approach to a Feasible Plaque Classification -- Real-Time Plaque Characterization and Visualization with Spectral Analysis of Intravascular Ultrasound Data -- Coronary Plaque Analysis by Multimodality Fusion -- Imaging of Plaque Cellular Activity with Contrast Enhanced MRI -- Inter- and Intra-Observer Variability Assessment of in Vivo Carotid Plaque Burden Quantification Using Multi-Contrast Dark Blood MR Images -- Three-Dimensional Volume Registration of Carotid MR Images -- Characterization of Shear Stress on the Wall of the Carotid Artery Using Magnetic Resonance Imaging and Computational Fluid Dynamics -- Numerical Modeling of Coronary Drug Eluting Stents -- Author Index.
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  • 2
    Publication Date: 2017-04-04
    Description: An integrated high-resolution magnetobiocyclostratigraphy including radioisotopic dating and astronomical tuning is presented for the interval between 15.29 and 14.17 Ma in the marine La Vedova section in northern Italy. The natural remanent magnetization is carried by the iron sulphide greigite and the resultant magnetostratigraphy can be correlated straightforwardly to the interval ranging from C5Bn.2n to C5ADn in the Astronomically Tuned Neogene Time Scale (ATNTS2004). Spectral analysis on high-resolution magnetic susceptibility and geochemical proxy records in the depth domain and, using our magnetobiostratigraphic age model, in the time domain demonstrate that the various scales of cyclicity in the section are related to astronomical climate forcing. Starting from our initial age model, larger-scale cycles were first tuned to eccentricity. This first-order tuning was followed by tuning the basic cycle to precession and boreal summer insolation using inferred phase relations between maxima in Ca/Al, redox-sensitive elements and Ba, and minima in magnetic susceptibility, and maxima in precession and minima in obliquity and boreal summer insolation. Our astronomical ages for reversal boundaries are supported by analysis of sea floor spreading rates and should replace the existing ages in the ATNTS2004 lacking direct astronomical control. Two major steps in the geochemical proxy records, astronomically dated at 15.074 and 14.489 Ma, coincide with abrupt changes in sedimentation rate, and are the result of the combined effect of the ∼400-kyr eccentricity cycle superimposed upon a longer-term climatic or tectonic induced trend.
    Description: Published
    Description: 254–269
    Description: 2.2. Laboratorio di paleomagnetismo
    Description: JCR Journal
    Description: restricted
    Keywords: Middle Miocene ; Langhian ; Mediterranean ; astronomical tuning ; palaeomagnetism ; biostratigraphy ; environmental changes ; orbital forcing ; 04. Solid Earth::04.04. Geology::04.04.10. Stratigraphy ; 04. Solid Earth::04.05. Geomagnetism::04.05.06. Paleomagnetism
    Repository Name: Istituto Nazionale di Geofisica e Vulcanologia (INGV)
    Type: article
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  • 3
    Publication Date: 2019-07-17
    Description: The ability of models to elucidate climate and ice sheet dynamics at the Eocene-Oligocene climate transition (34 Ma) is limited by a reliance on present-day topography as a boundary condition. We present a reconstruction of the Antarctic palaeotopography at the E-O boundary that restores sediment eroded from the continent. Estimates of sediment volume surrounding Antarctica constrain our restoration. Using data from coring and seismic imaging and allowing for a moderate biogenic fraction, weathering reactions and sediment porosity, a source volume of 5-13 million cubic km is thought to have been removed from an area of ca. 13 million square km. Changes to the East Antarctic landscape by local, regional and continental-scale ice have been estimated using an ice sheet and erosion model. Material is restored in response to basal conditions under a range of modelled ice-sheet configurations. These models can restore 3-4 million cubic km to East Antarctica. In West Antarctica, factors including the variable position of the grounding line make it impractical to use quantitative erosion models. Here we link geological evidence for known or suspected remnants of Eocene topography with our understanding of processes and patterns of erosion and deposition to drive construction of potential surfaces. There are several options for geologically reasonable surfaces that imply 5-10 million cubic km of eroded volume. The uncertainty in eroded volume is muted by the transformation to palaeo-elevation because isostatic compensation generally limits the change in average regional elevation to 15-20% of the thickness eroded.
    Repository Name: EPIC Alfred Wegener Institut
    Type: Conference , notRev
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  • 4
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    In:  EPIC3XXXI SCAR Open Science Conference, Buenos AiresAugust, 3, 2010 p.
    Publication Date: 2019-07-17
    Description: ANTscape is a project of the Antarctic Climate Evolution (ACE) Research Program to develop a series of maps to show changes in Antarctic paleotopography over the last ~100 million years. The reconstructions will provide a base for summarising a range of paleoenvironmental data, and for use as inputs for the next generation of ice sheet-ice shelf models. The present-day bedrock topography from the SCAR BEDMAP project will be used as a starting point for reconstructing past paleotopography, moving to BEDMAP 2 when it becomes available. Six maps, one for each significant climatic regime or shift, are planned: 4, 14, 34, 50, 70 and 92 Ma. Work is well advanced on the map for 34 Ma (Wilson and Luyendyk, 2009, Geophysical Research Letters). This is a time that is far enough back for there to be a significantly different topography, but not so far back that reconstruction is seriously unconstrained. It is also of great interest to paleoclimatologists as the largely ice-free landscape on which the first continental ice-sheet formed. The maps prepared by ANTscape will depend not only on restoration of Antarctic continental geography by reversing tectonic movements and elevation changes, but also the restoration of sediment eroded from the continent and deposited around and beyond the Antarctic margin. This will require modeling changes to the Antarctic landscape from erosion (Jamieson et al., 2010, Earth & Planetary Science Letters) and estimates of sediment volumes through the Circum-Antarctic Stratigraphy and Paleobathymetry Project (CASP). For further information see www.ANTscape.aq
    Repository Name: EPIC Alfred Wegener Institut
    Type: Conference , notRev
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  • 5
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    In:  EPIC3Palaeogeography, Palaeoclimatology, Palaeoecology, 335-33, pp. 24-34
    Publication Date: 2019-07-17
    Repository Name: EPIC Alfred Wegener Institut
    Type: Article , isiRev
    Format: application/pdf
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  • 6
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    In:  EPIC311th International Symposium of Antarctic Earth Sciences (ISAES), EdinburghJuly 2011., 10
    Publication Date: 2019-07-17
    Repository Name: EPIC Alfred Wegener Institut
    Type: Conference , notRev
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  • 7
    Publication Date: 2019-07-17
    Description: ANTscape is an ACE project to develop over the next three years a series of maps to show the changes in Antarctic paleotopography over the last ~100 million years. The reconstructions will provide a base for summarising a range of paleoenvironmental data, and be useful both as inputs for the next generation of ice sheet-ice shelf models, and for credible and realistic visualization of past landscapes to promote wider appreciation of past changes in the Antarctic environment. The first meeting of the group in April 2009 in Leeds agreed that for younger periods (Cenozoic) the present-day bedrock topography from the SCAR BEDMAP project would be a useful starting point for reconstructing past paleotopography, moving to BEDMAP 2 when it became available. However for older periods researchers would have to draw more on current knowledge of plate movements, tectonic deformation, thermal evolution and personal geological experience. Because of the scarcity of geological data, it was recognised that the reconstructions would entail considerable geological interpretation. However it was acknowledged that even poorly constrained reconstructions would be a significant improvement on the current practice of using present day topography for models of past ice sheets, when we know past topography was different.The following six time slices, each representing a significant climatic regime or shift, were proposed for a map: 4, 14, 34, 50, 70 and 92 Ma, with work beginning first on a map for 34 Ma. This is a time that is far enough back for there to be a significantly different topography, but not so far back that reconstruction is seriously unconstrained. It is also of great interest to paleoclimatologists as the largely ice-free landscape on which the first continental ice-sheet formed. The group leader for this time slice is Doug Wilson. The group decided the maps could most conveniently be developed by considering the Antarctic as comprising three large regions: 1) West Antarctica: Marie Byrd Land, Antarctic Peninsula, Ellsworth Mountains, West Antarctic rift system, Weddell Sea and Ross Sea, 2) East Antarctica including Transantarctic Mountains, and 3) the Antarctic margin, comprising the continental shelf and slope as far as the continent- ocean transition. A number of procedural issues are under discussion by ANTscape members, and input is sought from ACE 2009 participants in order that the issues be resolved in 2009. These include the primary geospatial tools to be used, spatial resolution of the primary product, the organizational scheme for gridding the data, and data/document storage and access. For the moment a report on the Leeds workshop along with abstracts and many of the presentations given there can be found at http://groups.google.com/group/antscape?hl=en The maps prepared by ANTscape will depend not only restoration of Antarctic continental geography by reversing tectonic movements and elevation changes, but also the restoration of sediment eroded from the continent and deposited around and beyond the Antarctic margin. This will require close collaboration with ROSSmap and the Circum-Antarctic Stratigraphy and Paleobaythmetry Project (CASP).
    Repository Name: EPIC Alfred Wegener Institut
    Type: Conference , notRev
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  • 8
    Publication Date: 2024-04-17
    Description: We present Bedmap2, a new suite of gridded products describing surface elevation, ice-thickness and the seafloor and subglacial bed elevation of the Antarctic south of 60 S. We derived these products using data from a variety of sources, including many substantial surveys completed since the original Bedmap compilation (Bedmap1) in 2001. In particular, the Bedmap2 ice thickness grid is made from 25 million measurements, over two orders of magnitude more than were used in Bedmap1. In most parts of Antarctica the subglacial landscape is visible in much greater detail than was previously available and the improved datacoverage has in many areas revealed the full scale of mountain ranges, valleys, basins and troughs, only fragments of which were previously indicated in local surveys. The derived statistics for Bedmap2 show that the volume of ice contained in the Antarctic ice sheet (27 million km3) and its potential contribution to sea-level rise (58 m) are similar to those of Bedmap1, but the mean thickness of the ice sheet is 4.6% greater, the mean depth of the bed beneath the grounded ice sheet is 72m lower and the area of ice sheet grounded on bed below sea level is increased by 10 %. The Bedmap2 compilation highlights several areas beneath the ice sheet where the bed elevation is substantially lower than the deepest bed indicated by Bedmap1. These products, along with grids of data coverage and uncertainty, provide new opportunities for detailed modelling of the past and future evolution of the Antarctic ice sheets.
    Description: Published
    Description: 375–393
    Description: 1.8. Osservazioni di geofisica ambientale
    Description: 3.8. Geofisica per l'ambiente
    Description: JCR Journal
    Description: open
    Keywords: Antarctic bedrock topography ; Antarctic mass balance ; 01. Atmosphere::01.01. Atmosphere::01.01.02. Climate ; 02. Cryosphere::02.02. Glaciers::02.02.04. Ice ; 02. Cryosphere::02.02. Glaciers::02.02.05. Ice dynamics ; 02. Cryosphere::02.02. Glaciers::02.02.06. Mass balance
    Repository Name: Istituto Nazionale di Geofisica e Vulcanologia (INGV)
    Type: article
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  • 9
    Electronic Resource
    Electronic Resource
    Oxford, UK : Munksgaard International Publishers
    Allergy 60 (2005), S. 0 
    ISSN: 1398-9995
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Allergic rhinitis is a common condition which, at its most severe, can significantly impair quality of life despite optimal treatment with antihistamines and topical nasal corticosteroids. Allergen injection immunotherapy significantly reduces symptoms and medication requirements in allergic rhinitis but its use is limited by the possibility of severe systemic reactions. There has therefore been considerable interest in alternative routes for delivery of allergen immunotherapy, particularly the sublingual route. The objective was to evaluate the efficacy of sublingual immunotherapy (SLIT), compared with placebo, for reductions in symptoms and medication requirements. The Cochrane Controlled Clinical Trials Register, MEDLINE (1966–2002), EMBASE (1974–2002) and Scisearch were searched, up to September 2002, using the terms (Rhin* OR hay fever) AND (immunotherap* OR desensiti*ation) AND (sublingual). All studies identified by the searches were assessed by the reviewers to identify Randomized Controlled Trials involving participants with symptoms of allergic rhinitis and proven allergen sensitivity, treated with SLIT or corresponding placebo. Data from identified studies was abstracted onto a standard extraction sheet and subsequently entered into RevMan 4.1. Analysis was performed by the method of standardized mean differences (SMD) using a random effects model. P-values 〈 0.05 were considered statistically significant. Subgroup analyses were performed according to the type of allergen administered, the age of participants and the duration of treatment. Twenty-two trials involving 979 patients, were included. There were six trials of SLIT for house dust mite allergy, five for grass pollen, five for parietaria, two for olive and one each for, ragweed, cat, tree and cupressus. Five studies enrolled exclusively children. Seventeen studies administered the allergen by sublingual drops subsequently swallowed, three by drops subsequently spat out and two by sublingual tablets. Eight studies involved treatment for less than 6 months, 10 studies for 6–12 months and four studies for greater than 12 months. All included studies were double-blind placebo-controlled trials of parallell group design. Concealment of treatment allocation was considered adequate in all studies and the use of identical placebo preparations was almost universal. There was significant heterogeneity, most likely due to widely differing scoring systems between studies, for most comparisons. Overall there was a significant reduction in both symptoms (SMD −0.42, 95% confidence interval −0.69 to −0.15; P = 0.002) and medication requirements [SMD −0.43 (−0.63, −0.23); P = 0.00003] following immunotherapy. Subgroup analyses failed to identify a disproportionate benefit of treatment according to the allergen administered. There was no significant reduction in symptoms and medication scores in those studies involving only children but total numbers of participants was too small to make this a reliable conclusion. Increasing duration of treatment does not clearly increase efficacy. The total dose of allergen administered may be important but insufficient data was available to analyse this factor.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Science Inc
    Journal of the American Ceramic Society 88 (2005), S. 0 
    ISSN: 1551-2916
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: The specific heat capacity, thermal conductivity, and thermal diffusivity of a thermoplastic ceramic paste were investigated on a power-compensated, differential scanning calorimeter (DSC) using the heat capacity spectral analysis method developed by Merzlyakov and Schick for measuring these parameters on low thermal conductivity solids. The paste features an ultra-fine zinc oxide powder (a number-length mean diameter, D1,0, of 85 nm) as the discrete phase, and a thermoplastic continuous phase comprising a blend of organic waxes with a melting range of ca. 30°–70°C. This paste is formulated with a solids loading of 50 vol% and is currently used in a novel continuous casting process to manufacture pharmaceutical products. The properties of the paste were investigated over a temperature range encompassing the melt and solid states, and for solid loadings from 0 to 70 vol%. The results compare favorably with those obtained using transient line source and transient plane methods.
    Type of Medium: Electronic Resource
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