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  • 1
    Online Resource
    Online Resource
    Singapore :Springer Singapore Pte. Limited,
    Keywords: Internet of things. ; Electronic books.
    Type of Medium: Online Resource
    Pages: 1 online resource (157 pages)
    Edition: 1st ed.
    ISBN: 9789811333231
    Series Statement: Computer Architecture and Design Methodologies Series
    DDC: 006.31
    Language: English
    Note: Intro -- Preface -- Contents -- 1 Introduction -- 1.1 Internet of Things (IoT) -- 1.2 Machine Learning Accelerator -- 1.3 Organization of This Book -- References -- 2 Fundamentals and Literature Review -- 2.1 Edge Computing on IoT Devices -- 2.2 IoT Based Smart Buildings -- 2.2.1 IoT Based Indoor Positioning System -- 2.2.2 IoT Based Energy Management System -- 2.2.3 IoT Based Network Intrusion Detection System -- 2.3 Machine Learning -- 2.3.1 Machine Learning Basics -- 2.3.2 Distributed Machine Learning -- 2.3.3 Machine Learning Accelerator -- 2.3.4 Machine Learning Model Optimization -- 2.4 Summary -- References -- 3 Least-Squares-Solver for Shallow Neural Network -- 3.1 Introduction -- 3.2 Algorithm Optimization -- 3.2.1 Preliminary -- 3.2.2 Incremental Least-Squares Solver -- 3.3 Hardware Implementation -- 3.3.1 CMOS Based Accelerator -- 3.3.2 RRAM-Crossbar Based Accelerator -- 3.4 Experiment Results -- 3.4.1 CMOS Based Results -- 3.4.2 RRAM Based Results -- 3.5 Conclusion -- References -- 4 Tensor-Solver for Deep Neural Network -- 4.1 Introduction -- 4.2 Algorithm Optimization -- 4.2.1 Preliminary -- 4.2.2 Shallow Tensorized Neural Network -- 4.2.3 Deep Tensorized Neural Network -- 4.2.4 Layer-wise Training of TNN -- 4.2.5 Fine-tuning of TNN -- 4.2.6 Quantization of TNN -- 4.2.7 Network Interpretation of TNN -- 4.3 Hardware Implementation -- 4.3.1 3D Multi-layer CMOS-RRAM Architecture -- 4.3.2 TNN Accelerator Design on 3D CMOS-RRAM Architecture -- 4.4 Experiment Results -- 4.4.1 TNN Performance Evaluation and Analysis -- 4.4.2 TNN Benchmarked Result -- 4.4.3 TNN Hardware Accelerator Result -- 4.5 Conclusion -- References -- 5 Distributed-Solver for Networked Neural Network -- 5.1 Introduction -- 5.1.1 Indoor Positioning System -- 5.1.2 Energy Management System -- 5.1.3 Network Intrusion Detection System -- 5.2 Algorithm Optimization. , 5.2.1 Distributed Neural Network -- 5.2.2 Online Sequential Model Update -- 5.2.3 Ensemble Learning -- 5.3 IoT Based Indoor Positioning System -- 5.3.1 Problem Formulation -- 5.3.2 Indoor Positioning System -- 5.3.3 Experiment Results -- 5.4 IoT Based Energy Management System -- 5.4.1 Problem Formulation -- 5.4.2 Energy Management System -- 5.4.3 Experiment Results -- 5.5 IoT Based Network Security System -- 5.5.1 Problem Formulation -- 5.5.2 Network Intrusion Detection System -- 5.5.3 Experiment Results -- 5.6 Conclusion and Future Works -- References -- 6 Conclusion and Future Works -- 6.1 Conclusion -- 6.2 Recommendations for Future Works -- References.
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  • 2
    Publication Date: 2016-01-07
    Description: Suspended particles from the lower Changjiang were collected monthly from 2003 to 2011, which corresponds to the three construction periods of the Three Gorges Dam. Organic carbon (%OC), organic carbon to total nitrogen molar ratio, stable carbon isotope, and terrestrial biomarkers were examined. Rating curve studies were applied for the temporal trend analysis. The composition of particulate lignin phenols exhibited clear annual and periodic variations but only minor seasonal changes. Lignin phenol ratios (vanillyl/syringyl and cinnamyl/vanillyl) indicated that the terrigenous organic matter (OM) was primarily composed of woody and nonwoody tissue derived from angiosperm plants. The low-lignin phenol yields (Λ8) in combination with higher acid to aldehyde ratios reflected a substantial contribution fromsoil OM to the particle samples or modifications during river transport. The temporal shift of the lignin phenol vegetation index with the sediment load during the flood seasons revealed particulate organic matter (POM) erosion from soils and the impact of hydrodynamic processes. The dam operations affected the seasonal variability of terrigenous OM fluxes, although the covariation of lignin and sediment loads with discharged water implies that unseasonal extreme conditions and climate changemost likely had larger influences, because decreases in the sediment load and lignin flux alter the structure and composition of particulate OM (POM) on interannual time scales, indicating that they may be driven by climate variability. The modification of the composition and structure of POM will have significant impacts on regional carbon cycles and marine ecosystems.
    Repository Name: EPIC Alfred Wegener Institut
    Type: Article , isiRev
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  • 3
    Publication Date: 2015-08-13
    Description: Background: The prevalence of alcohol intake is increasing among women in some populations. Alcohol consumption plays an important role in the risk of major cardiovascular outcomes and total mortality. Here, we conducted a meta-analysis to estimate the association between alcohol intake and major cardiovascular outcomes or total mortality in women compared with men. Methods: We searched the PubMed, Embase, and the Cochrane Library databases for relevant articles published prior to June 2014. Among these potential included prospective studies, the different dose categories of alcohol intake were compared with the lowest alcohol intake or non-drinkers between women and men for the outcomes of major cardiovascular or total mortality. Results: We included 23 prospective studies (18 cohorts) reporting data on 489,696 individuals. The summary relative risk ratio (RRR; female to male) for total mortality was significantly increased with moderate alcohol intake compared with the lowest alcohol intake (RRR, 1.10; 95 % confidence interval [CI]: 1.00–1.21; P = 0.047); no such significance was observed with other levels of alcohol intake (low intake: RRR, 1.07; 95 % CI: 0.98–1.17; P = 0.143; heavy intake: RRR, 1.09; 95 % CI: 0.99–1.21; P = 0.084). There was no evidence of a sex difference in the relative risk for coronary disease, cardiac death, stroke, or ischemic stroke between participants with low to heavy alcohol intake compared with those who never consumed alcohol or had the lowest alcohol intake. Conclusions: Women with moderate to heavy alcohol intake had a significantly increased risk of total mortality compared with men in multiple subpopulations. Control of alcohol intake should be considered for women, particularly for young women who may be susceptible to binge drinking.
    Electronic ISSN: 1471-2458
    Topics: Medicine
    Published by BioMed Central
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  • 4
    Publication Date: 2015-10-29
    Description: Lipoxin A4 activates alveolar epithelial sodium channel gamma via the microRNA-21/PTEN/AKT pathway in lipopolysaccharide-induced inflammatory lung injury Laboratory Investigation 95, 1258 (November 2015). doi:10.1038/labinvest.2015.109 Authors: Wei Qi, Hui Li, Xiao-Hong Cai, Jia-Qi Gu, Jin Meng, Hai-Qing Xie, Jun-Li Zhang, Jie Chen, Xian-Guan Jin, Qian Tang, Yu Hao, Ye Gao, Ai-Qing Wen, Xiang-Yang Xue, Fang Gao Smith & Sheng-Wei Jin
    Print ISSN: 0023-6837
    Electronic ISSN: 1530-0307
    Topics: Medicine
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  • 5
    Publication Date: 2015-10-30
    Description: We have performed a comprehensive first-principle computational study of the electronic properties of one-dimensional phosphorene nanotubes (PNTs), and the strain effect on the mechanical and electrical properties of PNTs, including the elastic modulus, energy bandstructure, and carrier effective mass. The study has demonstrated that the armchair PNTs have semiconducting properties along the axial direction and the carrier mobility can be significantly improved by compressive strain. The hole mobility increases from 40.7 cm 2 /V s to 197.0 cm 2 /V s as the compressive strain increases to −5% at room temperature. The investigations of size effect on armchair PNTs indicated that the conductance increases significantly as the increasing diameter. Overall, this study indicated that the PNTs have very attractive electronic properties for future application in nanomaterials and devices.
    Print ISSN: 0021-8979
    Electronic ISSN: 1089-7550
    Topics: Physics
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  • 6
    Publication Date: 2015-10-24
    Description: Author(s): B. Freelon, Yu Hao Liu, Jeng-Lung Chen, L. Craco, M. S. Laad, S. Leoni, Jiaqi Chen, Li Tao, Hangdong Wang, R. Flauca, Z. Yamani, Minghu Fang, Chinglin Chang, J.-H. Guo, and Z. Hussain We perform a combined experimental-theoretical study of the Fe-oxychalcogenides ( FeO C h ) series La 2 O 2 Fe 2 O M 2 ( M = S , Se), which are among the latest Fe-based materials with the potential to show unconventional high- T c superconductivity (HTSC). A combination of incoherent Hubbard features in x-ray absorp… [Phys. Rev. B 92, 155139] Published Fri Oct 23, 2015
    Keywords: Electronic structure and strongly correlated systems
    Print ISSN: 1098-0121
    Electronic ISSN: 1095-3795
    Topics: Physics
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  • 7
    Publication Date: 2018-01-27
    Description: Ovarian cancer is one of the most common female malignancies, and cisplatin-based chemotherapy is routinely used in locally advanced ovarian cancer patients. Acquired or de novo cisplatin resistance remains the barrier to patient survival, and the mechanisms of cisplatin resistance are still not well understood. In the current study, we found that colony-stimulating-factor-1 receptor (CSF-1R) was upregulated in cisplatin-resistant SK-OV-3 and CaoV-3 cells. Colony-stimulating-factor-1 receptor knockdown suppressed proliferation and enhanced apoptosis in cisplatin-resistant SK-OV-3 and CaoV-3 cells. However, CSF-1R overexpression had inverse effects. While parental SK-OV-3 and CaoV-3 cells were more resistant to cisplatin after CSF-1R overexpression, CSF-1R knockdown in SK-OV-3 and CaoV-3 cells promoted cisplatin sensitivity. Overexpression and knockdown studies also showed that CSF-1R significantly promoted active AKT and ERK1/2 signalling pathways in cisplatin-resistant cells. Furthermore, a combination of cisplatin and CSF-1R inhibitor effectively inhibited tumour growth in xenografts. Taken together, our results provide the first evidence that CSF-1R inhibition can sensitize cisplatin-refractory ovarian cancer cells. This study may help to increase understanding of the molecular mechanisms underlying cisplatin resistance in tumours.
    Print ISSN: 0263-6484
    Electronic ISSN: 1099-0844
    Topics: Biology , Medicine
    Published by Wiley-Blackwell
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  • 8
    Publication Date: 2018-02-07
    Description: Journal of the American Chemical Society DOI: 10.1021/jacs.7b11036
    Print ISSN: 0002-7863
    Electronic ISSN: 1520-5126
    Topics: Chemistry and Pharmacology
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  • 9
    Publication Date: 2018-10-11
    Description: Hsp90ab1 stabilizes LRP5 to promote epithelial–mesenchymal transition via activating of AKT and Wnt/β-catenin signaling pathways in gastric cancer progression Hsp90ab1 stabilizes LRP5 to promote epithelial–mesenchymal transition via activating of AKT and Wnt/β-catenin signaling pathways in gastric cancer progression, Published online: 10 October 2018; doi:10.1038/s41388-018-0532-5 Hsp90ab1 stabilizes LRP5 to promote epithelial–mesenchymal transition via activating of AKT and Wnt/β-catenin signaling pathways in gastric cancer progression
    Print ISSN: 0950-9232
    Topics: Medicine
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  • 10
    Publication Date: 2016-09-21
    Description: Organic Letters DOI: 10.1021/acs.orglett.6b02424
    Print ISSN: 1523-7060
    Electronic ISSN: 1523-7052
    Topics: Chemistry and Pharmacology
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