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  • Springer  (28)
  • 2015-2019
  • 1995-1999  (17)
  • 1990-1994  (7)
  • 1985-1989  (4)
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Year
  • 1
    Electronic Resource
    Electronic Resource
    Model-independent separation of structure functions over an extended kinematical region (1994)
    Springer
    The European physical journal 349 (1994), S. 161-168 
    Details
    ISSN: 1434-601X
    Keywords: 25.30.Fj ; 21.10.Pc ; 02.60.Ed
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract A method for the separation of structure functions in (e, e′ p) experiments is proposed, which is an extension of the traditional Rosenbluth-type techniques of [1,2]. In our approach, we use a very flexible Ansatz to describe the structure functions within an extended kinematical regionG and determine its free parameters with a x2 minimization. The procedure is tested by pseudo data (12C(e, e′p)11Bg.s.) in the quasi-free region.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01291175
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  • 2
    Electronic Resource
    Electronic Resource
    Properties of high-energy pions emitted from heavy-ion collisions at 1 GeV/nucleon (1995)
    Springer
    The European physical journal 352 (1995), S. 175-179 
    Details
    ISSN: 1434-601X
    Keywords: 25.75.+r
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract Positively charged pions and protons from collisions of Ne+NaF and Au+Au at 1 GeV/nucleon incident energy were measured near midrapidity. The center-of-mass pion spectra deviate from a Maxwell-Boltzmann distribution. The slope of the high-energy part of the pion spectra varies significantly with the system mass and little with the size of the reaction zone. While the total pion yield rises linearly with the number of participant nucleons, the highenergy component increases more than linearly.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01298905
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  • 3
    Electronic Resource
    Electronic Resource
    Distribution of metals in annual rings of the beech (Fagus sylvatica) as an expression of environmental changes (1986)
    Springer
    Cellular and molecular life sciences 42 (1986), S. 537-542 
    Details
    ISSN: 1420-9071
    Keywords: Annual ring ; beech ; trace metals ; environmental pollution
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Annual rings of 140–160-year-old beeches (Fagus sylvatica) from St. Ingbert, Saarland (FRG) were prepared and analyzed for 14 metals by atomic absorption spectroscopy. According to the chronological variations of their concentrations, the elements could be divided into three groups: 1) Metals without any tendency for chronological changes. This was established for Na, K, Cu, Cr, Co, Ni, Pb, and Cd. 2) Metals with a recent decrease of their concentrations, appropriate for Ca, Mg, Mn, and Zn. 3) Metals with a recent tendency to increase, e.g. Fe and Al. These variations are discussed in connection with the industrial history of the Saarland region and the influence of acid immissions which may alter the soil and thereby the trace element metabolism of the trees with consequences for the vitality of the plants.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01946693
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  • 4
    Electronic Resource
    Electronic Resource
    On an infinite class of Steiner systems constructed from affine spaces (1986)
    Springer
    Archiv der Mathematik 47 (1986), S. 376-378 
    Details
    ISSN: 1420-8938
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mathematics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01191366
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  • 5
    Electronic Resource
    Electronic Resource
    Complement C1q and C3 mRNA expression in the frontal cortex of Alzheimer's patients (1995)
    Springer
    Journal of molecular medicine 73 (1995), S. 465-471 
    Details
    ISSN: 1432-1440
    Keywords: Complement ; mRNA ; Brain ; Aging ; Alzheimer's disease
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The levels and cellular localization of mRNA for complement C1q and C3 were examined by RNA gel blot and nonradioactive in situ hybridization in the frontal cortex of patients with Alzheimer's disease (AD) and age-matched controls. We found that the hybridization signal for C1q mRNA was markedly increased (approx. 3.5-fold) in the frontal cortex of AD patients compared to that in age-matched controls. In contrast to previous reports we also found that the levels of C3 mRNA, although well expressed, did not differ significantly between AD cases and age-matched controls. Nonradioactive in situ hybridization using digoxigenin-labeled riboprobes revealed that transcripts coding for both C1q and C3 were closely associated with neurons. These results support the hypothesis that complement could play a role in neuronal degeneration which has been observed in the brain of AD patients.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00202265
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  • 6
    Electronic Resource
    Electronic Resource
    Clinical features of type III hyperlipoproteinemia: analysis of 64 patients (1993)
    Springer
    Journal of molecular medicine 71 (1993), S. 362-366 
    Details
    ISSN: 1432-1440
    Keywords: Apolipoprotein E ; Atherosclerosis ; Familial dysbetalipoproteinemia ; Genetic polymorphism ; Type III hyperlipoproteinemia
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The clinical and biochemical characteristics of type III hyperlipoproteinemia are described in 64 patients (35 males and 29 females). Homozygosity for apolipoprotein E2, the presence of an abnormally cholesterol-rich very low density lipoprotein fraction (β-VLDL) and an elevated ratio of very low density lipoprotein cholesterol to plasma triglycerides (〉0.3; normal ratio about 0.2) were the basis for the diagnosis. Mean serum cholesterol and triglyceride concentrations at the first visit in the clinic were 426 ± 221 and 719 ±996 mg/dl, respectively. The mean age at diagnosis of the disorder was 49 years in males and 53 years in females. There was a high prevalence of obesity (72%), xanthomas (42%), and atherosclerosis (39%), especially peripheral vascular disease (31%). Early and correct diagnosis of this familial lipoprotein disorder seems necessary because of the prompt and beneficial response to therapeutic interventions.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00186624
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  • 7
    Electronic Resource
    Electronic Resource
    Tail-to-tail orientation of the Atlantic salmon alpha- and beta-globin genes (1994)
    Springer
    Journal of molecular evolution 38 (1994), S. 28-35 
    Details
    ISSN: 1432-1432
    Keywords: α-globin ; β-globin ; Atlantic salmon ; Genomic organization
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract We report the cloning of a cDNA and two corresponding β-globin genes of the Atlantic salmon (Salmo salar L.) as well as two genes for α-globins. Nucleotide sequence analysis of the cDNA shows that the predicted β-globin peptide comprises 148 amino acids with a calculated molecular mass of 16,127 Da and an overall amino acid similarity of 40–50% to higher vertebrates and 60–90% to fish sequences. The study of the genomic organization of α- and β-globin genes shows that, as is the case in Xenopus, the salmon genes are adjacent. Two sets of linked α- and β-globin genes were isolated and restriction-enzyme polymorphisms indicate that they belong to two distinct loci, possibly as a result of the salmon tetraploidy. In each locus the α- and β-globin genes are oriented 3′ to 3′ relative to each other with the RNA coding sequences located on opposite DNA strands. This is the first evidence for this type of arrangement found for globin genes. Moreover, while the linkage found in salmon and Xenopus supports the hypothesis of an initial tandem duplication of a globin ancestor gene, our results raise the question of the actual original orientation of the duplicated genes.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00175492
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  • 8
    Electronic Resource
    Electronic Resource
    Small-cell carcinoma of the ovary of the hypercalcemic type in an 8-year-old girl (1999)
    Springer
    Pediatric surgery international 15 (1999), S. 431-434 
    Details
    ISSN: 1437-9813
    Keywords: Key words Ovarian tumor ; Children ; Hypercalcemia ; Small-Cell carcinoma
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Tumors of the ovary in girls represent about 80% of pediatric genital tumors; approximately 30% of these tumors are malignant. The risk of malignancy increases with decreasing age. The most frequent finding is a teratoma; other tumors are rare. Small-cell carcinoma (SCCO) of the ovary is extremely rare, occurring mostly in young women. We present an 8-year-old girl with a SCCO of the hypercalcemic type. The findings and treatment are discussed with emphasis on the poor prognosis in these patients, even in stage 1 disease. The current literature is reviewed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s003830050625
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  • 9
    Electronic Resource
    Electronic Resource
    Fracture of the lumbar vertebral ring apophysis imitating disc herniation (1991)
    Springer
    Acta neurochirurgica 113 (1991), S. 52-56 
    Details
    ISSN: 0942-0940
    Keywords: Spine ; intervertebral discs ; fractures ; sciatica
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Three cases of fracture of the lumbar ring apophysis representing type I, II, and III are described in detail and the natural history of these fractures is discussed. The symptoms of apophyseal fractures are usually low back pain, sciatica, tension signs, and neurological deficits, thus imitating the symptoms of lumbar disc herniation. Plain radiography and magnetic resonance are often inconclusive and computed tomography is essential for the true diagnosis. An explanation of the different types of fractures, based on the osteogenesis of the human vertebra, is proposed. Recognition of these fractures is essential for proper planing of surgery, and apophyseal ring fractures must be suspected when children and young adults show signs of lumbar disc herniation.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01402115
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  • 10
    Electronic Resource
    Electronic Resource
    Ratio of complement receptor over Fc-receptor III expression: A sensitive parameter to monitor granulocyte-macrophage colony-stimulating factor effects on neutrophils (1991)
    Springer
    Annals of hematology 62 (1991), S. 135-140 
    Details
    ISSN: 1432-0584
    Keywords: Granulocyte-macrophage colony-stimulating factor (GM-CSF) ; Granulocyte surface receptors ; Therapy monitoring
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary In vitro activation of human granulocytes leads to altered expression of distinct surface antigens. Compared with the changes observed with classic activating reagents such as the phorbol ester PMA similar, but less pronounced alterations of surface antigen expression were observed upon granulocyte activation with human recombinant granulocyte-macrophage colony-stimulating factor (hrGM-CSF). In particular, stimulation with hrGM-CSF is followed by an enhanced expression of the complement receptors CD35 (CR1) and CD11b (CR3) while the low affinity Fc-γ receptor CD16 (FcRIII) is downregulated. In order to investigate whether there are similar effects under in vivo conditions, we studied the granulocytes from patients undergoing rhGM-CSF therapy before, during, and after treatment. We found a marked increase in CD35 (CR1) and CD11b (CR3) expression and a substantial decrease or even loss of CD16 (FcRIII) on these granulocytes. These changes correlated well with our in vitro data and occurred extremely rapidly after therapy onset. Furthermore, therapy monitoring using ratios calculated by the mean fluorescence channel numbers of CR and FcRIII stainings may combine the advantage of high sensitivity with high reproducibility as a result of the contrasting change in CR and FcRIII expression during granulocyte activation. Being nonparametric values, such ratios are not influenced by individual flow cytometry standardization. Taken together, these activation-associated changes of surface receptor expression and especially of CR over FcRIII ratios are useful parameters for monitoring the in vivo effects of rhGM-CSF.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01702927
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