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  • 1
    Electronic Resource
    Electronic Resource
    Iron-doped semi-insulating InP grown by chemical beam epitaxy (1989)
    Woodbury, NY : American Institute of Physics (AIP)
    Applied Physics Letters 54 (1989), S. 2336-2338 
    Details
    ISSN: 1077-3118
    Source: AIP Digital Archive
    Topics: Physics
    Notes: We have prepared Fe-doped InP epilayers by chemical beam epitaxy using a thermal atomic Fe beam. Epilayers having high resistivities ((approximately-greater-than)107 Ω cm) were obtained over a wide range of Fe concentrations. Resistivities as high as 1.3×108 Ω cm have been obtained. Such resistivity is almost equal to the theoretical value of 1.37×108 Ω cm that we estimate for intrinsic InP. The current-voltage characteristics exhibit both an ohmic and a space-charge-limited regime, and are consistent with the theory of single-carrier injection into a trap-free insulator. Pinning of the Fermi level near midgap by Fe-related deep levels is the mechanism by which the epilayer is made highly resistive. At room temperature, these traps are apparently deep enough that the carrier emission rate is negligible.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.101120
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  • 2
    Electronic Resource
    Electronic Resource
    Quantum shift of the optical absorption edge in ultrathin amorphous hydrogenated germanium (1987)
    Woodbury, NY : American Institute of Physics (AIP)
    Applied Physics Letters 51 (1987), S. 264-266 
    Details
    ISSN: 1077-3118
    Source: AIP Digital Archive
    Topics: Physics
    Notes: The optical absorption coefficient in ultrathin (∼10 A(ring)) hydrogenated amorphous germanium (a-Ge:H) layers deposited on hydrogenated amorphous silicon layers was determined by in situ reflectivity measurements. The decrease in the absorption coefficient in the ultrathin a-Ge:H layers, compared to that of thick films, is explained by an upward shift in the conduction band edge due to quantum confinement of electrons with effective mass of 0.4m0.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.98468
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  • 3
    Electronic Resource
    Electronic Resource
    Effect of sputtering parameters on the magnetic properties of Mo-Permalloy (1988)
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 64 (1988), S. 5670-5672 
    Details
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Sputtered Mo-Permalloy thin film is expected to possess great potentiality in soft magnetic properties which can be realized chiefly by controlling sputtering conditions. The effects of sputtering parameters, such as argon pressure, bias voltage, and preheating temperature, on the magnetic properties, of FeNiMo sputtered films have been investigated. The magnetic anisotropy field Hk was found to decrease with the raising preheating temperature while coercivity Hc presented the contrary trend. High effective permeability can be acquired at low argon pressure, adequate preheating temperature, and bias voltage. Close relationships among effective permeability, anisotropy field, magnetostriction coefficient, and half-height width Δθ50 were found. Annealing is available for increasing effective permeability.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.342269
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  • 4
    Electronic Resource
    Electronic Resource
    Expression of Interleukin-17 in Ischemic Brain Tissue (2005)
    Oxford, UK; Malden, USA : Blackwell Science Ltd
    Scandinavian journal of immunology 62 (2005), S. 0 
    Details
    ISSN: 1365-3083
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Ischemic brain injury is acute local inflammation, leading to accumulation of pro-inflammatory cytokines. Cytokines influence the recruitment of leucocytes and play a key role in the inflammatory injury processes. Recently, a number of studies have demonstrated a close relationship between brain ischemia and cytokines. Interleukin-17 (IL-17) is a newly identified T-cell-specific cytokine. In this study, we evaluated the source and the action of IL-17 over the course of cerebral ischemia in rats (Sprague-Dawley) and humans. The levels of IL-17 in the ischemic hemisphere of the human brain, which was removed at necropsy, were assayed immunohistochemically. In rats, permanent middle cerebral artery occlusion (pMCAO) was obtained by inserting nylon monofilament into the right external carotid artery, occluding the right middle cerebral artery. The expression of IL-17 mRNA in rat was assayed using oligoprobe in situ hybridization. IL-17 production by neuroglial cells was assayed by double-staining using antibody glial fibrillary acidic protein (GFAP) and antibody IL-17. Levels of IL-17 were elevated in the ischemic hemispheres of human brain compared with the opposite normal hemispheres and peaked at days 3–5 after brain ischemia. The IL-17-positive cells were found in the ischemic lesion region. IL-17 mRNA was also elevated in ischemic hemispheres of pMCAO-operated rats, which were slightly elevated after 1 h and peaked at 6 days. IL-17 and GFAP double-stained were extensive in rat ischemic hemisphere. The ischemia-induced IL-17 expression in human brain reported here for the first time was very similar to that in rat model except that the peak was slightly earlier. We found for the first time that IL-17 was involved in an intense inflammatory reaction of brain ischemic injury in human. In pMCAO-operated rats, our findings suggest that IL-17 is produced by the neuroglial cells in the brain region undergoing ischemic insult. We suggest that in additional to T cells the neuroglial cell may be another cellular origin of IL-17 in later progression of brain ischemia.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-3083.2005.01683.x
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  • 5
    Electronic Resource
    Electronic Resource
    Stability of lyophilized and reconstituted plasma/albumin-free recombinant human factor VIII (ADVATE rAHF-PFM) (2005)
    Oxford, UK : Blackwell Science Ltd
    Haemophilia 11 (2005), S. 0 
    Details
    ISSN: 1365-2516
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Summary.  Traditionally the serum protein albumin has been used to stabilize lyophilized recombinant factor VIII (rFVIII) products. Advanced rFVIII products have now been developed that employ other stabilizers. ADVATE antihaemophilic factor (recombinant), plasma/albumin-free method (rAHF-PFM) utilizes trehalose and mannitol as stabilizers in the lyophilized preparation. An extensive in vitro evaluation was conducted on the stability of rAHF-PFM as measured by retained activity over time. Both lyophilized and reconstituted rAHF-PFM were analysed, and the full range of available potencies were tested under varying temperature conditions. Lyophilized rAHF-PFM exhibited a high degree of stability under a range of conditions. The mean retained activity of 15 rAHF-PFM lots (ranging from low to maximal potency) at 5 °C for 30 months was 91.6% (95% CI, 88.9–94.3%) of initial potency. rAHF-PFM also remained highly stable after storage at room temperature for 18 months, with 82.0% (95% CI, 79.2–84.9%) of initial activity retained at 25 °C and 79.1% (95% CI, 76.2–81.9%) at 30 °C. All other parameters, including moisture, appearance, solubility, pH and aggregation remained within the established product specifications. The mean retained activity after 1 month of storage at 40 °C was 94.0% (95% CI, 92.4–95.6%). A high temperature excursion to 40 °C for 2 weeks did not compromise subsequent stability of the lyophilized powder either under refrigeration or at room temperature. Reconstituted samples from 11 rAHF-PFM lots retained an average of 92.0% (95% CI, 89.8–94.3%) activity after 24 h. The present study provides evidence of good stability at differing temperatures of an albumin-free formulated rFVIII product.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2516.2005.01128.x
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  • 6
    Electronic Resource
    Electronic Resource
    Synthesis of Nano-Sized Co-Sb Compounds through Solvothermal Routes (2008)
    s.l. ; Stafa-Zurich, Switzerland
    Solid state phenomena Vol. 136 (Feb. 2008), p. 57-62 
    Details
    ISSN: 1662-9779
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Physics
    Notes: Skutterudite materials have received great attention because their promising propertiesfor thermoelectric (TE) applications. Among the family of skutterudites, CoSb3 has been intensivelyinvestigated due to its large electrical conductivity and Seebeck coefficient. However, its thermalconductivity is too high to make it an effective TE material. Nanostructuring of CoSb3 has thedesirable effects of reducing its lattice thermal conductivity as the point imperfections or grainboundaries can scatter phonons (heat carrier) more effectively than electrons (charge carrier). In thisstudy, nanostructured CoSb3 was synthesized by solvothermal routes using CoCl2·6H2O and SbCl3as precursors dissolved in anhydrous ethanol with the reaction temperature kept at 240°C. Inaddition to the CoSb3 phase, other Co-Sb compounds were also formed during the reaction process.In this paper, we investigated the effects of processing parameters, such as concentration ofCoCl2·6H2O, SbCl3 and NaBH4 in ethanol and thermal duration of solvothermal synthesis, on theyield of CoSb3 phase
    Type of Medium: Electronic Resource
    URL: http://www.tib-hannover.de/fulltexts/2011/0528/02/24/transtech_doi~10.4028%252Fwww.scientific.net%252FSSP.136.57.pdf
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  • 7
    Electronic Resource
    Electronic Resource
    The activity of flavone acetic acid (NSC 347512) on human colon cancer cells in vitro (1986)
    Springer
    Investigational new drugs 4 (1986), S. 289-293 
    Details
    ISSN: 1573-0646
    Keywords: flavone acetic acid ; cytotoxicity ; colon cancer
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Abstract Flavone acetic acid (FAA) was incubated for 1 to 48 hr with 3 established human colon cancer cell lines endowed with distinct degrees of phenotypic properties. All 3 lines responded to FAA in almost identical fashion; when incubated with the drug for only 1 hr, an initial decrease in survival was observed for concentrations of 250 μg/ml but no further increments in cytotoxicity were elicited when the concentration of FAA was augmented. Increasing the length of treatment yielded relatively modest increments (about 1 log) in cell killing only after an interval of 48 hr and only at the highest concentration (1000 μg/ml). Because of these relatively poor cytotoxic effects and because the therapeutic range of FAA is so narrow, we conclude that this agent will not be a valuable contribution to the antitumor arsenal, at least for colon cancer.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00173501
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  • 8
    Electronic Resource
    Electronic Resource
    Prebiotic synthesis of imidazole-4-acetaldehyde, imidazole-4-glycol and imidazole-4-ethanol (1986)
    Springer
    Origins of life and evolution of the biospheres 16 (1986), S. 275-276 
    Details
    ISSN: 1573-0875
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Geosciences
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02422023
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  • 9
    Electronic Resource
    Electronic Resource
    The prebiotic synthesis of histidine and histidyl-histidine (1989)
    Springer
    Origins of life and evolution of the biospheres 19 (1989), S. 258-259 
    Details
    ISSN: 1573-0875
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Geosciences
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02388839
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  • 10
    Electronic Resource
    Electronic Resource
    The TFTR Lithium Blanket Module program (1985)
    Springer
    Journal of fusion energy 4 (1985), S. 57-77 
    Details
    ISSN: 1572-9591
    Keywords: blanket ; lithium ; neutronics ; tokamak ; tritium
    Source: Springer Online Journal Archives 1860-2000
    Topics: Energy, Environment Protection, Nuclear Power Engineering
    Notes: Abstract The Lithium Blanket Module (LBM) is an approximately 80×80×80 cm cubic module, representative of a helium-cooled lithium oxide fusion reactor blanket module, that will be installed on the TFTR (Tokamak Fusion Test Reactor) in late 1986. The principal objective of the LBM Program is to perform a series of neutron transport and tritium-breeding measurements throughout the LBM when it is exposed to the TFTR toroidal fusion neutron source, and to compare these data with the predictions of Monte Carlo (MCNP) neutronics codes. The LBM consists of 920 2.5-cm diameter breeder rods constructed of lithium oxide (Li2O) pellets housed in thin-walled stainless steel tubes. Procedures for mass-producing 25,000 Li2O pellets with satisfactory reproducibility were developed using purified Li2O powder, and fabrication of all the breeder rods was completed in early 1985. Tritium assay methods were investigated experimentally using both small lithium metal samples and LBM-type pellets. This work demonstrated that the thermal extraction method will be satisfactory for accurate evaluation of the minute concentrations of tritium expected in the LBM pellets (0.1–1 nCi/g).
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01051639
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