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  • Aortic bifurcation  (1)
  • Aldosterone
  • Anemometer, Thies Clima; Calculated; DATE/TIME; Glaciers Austria; HEIGHT above ground; Pegelstation_Vernagtbach_meteorology; Unmanned weather station/meteorological observation; UWST; Vernagtferner, Ötztaler Alpen, Austria; Wind direction; Wind direction, relative share; Wind direction, standard deviation; Wind speed; Wind speed, maximum; Wind speed, minimum
  • Hypertension
  • 1990-1994  (2)
  • 1993  (2)
Document type
Keywords
Publisher
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  • 1990-1994  (2)
Year
  • 1
    ISSN: 1432-1440
    Keywords: Na+/H+ antiport ; Hypertension ; Diabetic nephropathy ; Hereditary factors
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The incidence of diabetic nephropathy in patients with insulin-dependent diabetes mellitus (IDDM) may depend on factors other than the quality of diabetes control. Hypertension is an additional factor associated with a high degree of renal involvement in IDDM. One abnormality consistantly observed in various tissues of patients with essential hypertension is enhanced activity of the Na+/H+ antiport. In the present study we have therefore studied platelet antiport activity in 41 healthy subjects (control), in 22 patients with untreated essential hypertension (EH), and in 35 normotensive IDDM patients (type 1). Of these patients 17 exhibited signs of diabetic nephropathy (group 1) while 18 had no evidence for renal involvement of IDDM in spite of a duration of IDDM of at least 10 years (group 2). The two IDDM patient groups were undistinguishable with respect to age, body mass index, and arterial blood pressure (group 1, 117.9±2.4/78.4±1.5 mmHg; group 2, 113.9±3.6/76.1±1.8 mmHg). Antiporter activity was determined from the rate of cell volume changes induced by propionic acid. Platelet Na+/H+ exchange activity averaged 23.43±0.43 10−3·s−1 in control subjects and was markedly elevated in EH (28.38±0.62 10−3·s−1 P〈0.01). Antiport activity in group 2 patients without nephropathy averaged 24.54±0.57 10−3·s−1 and was undistinguishable from the control group. However, platelet Na+/H+ antiport activity was significantly stimulated in group 1 patients with nephropathy as compared to group 2(26.95±0.73 10−3. s−1 ; P〈0.025). Our results show that renal involvement in IDDM is associated with enhanced activity of the platelet Na+/H+ antiport.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1432-1084
    Keywords: Arteries ; Stents ; Atherosclerotic occlusive disease ; Aortic bifurcation ; Percutaneous transluminal angioplasty
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Eighteen patients with atherosclerotic disease of the aorto-iliac bifurcation were treated with percutaneously implantable, balloon expandable tantalum stents. Stenting indications were percutaneous transluminal angioplasty (PTA) —resistant stenoses and long aorto-iliac occlusions. The vascular prostheses were inserted by bilateral femoral approach and dilated simultaneously, their proximal parts being deployed in parallel in the aorta and their distal parts anchored in the common iliac arteries (kissing-stent method). In aorto-iliac occlusions, local fibrinolysis was used to facilitate guide wire passage. Within 20 months (the duration of longest observation), no major acute or late complications occurred. Clinical symptoms improved immediately in all patients. Deterioration of clinical symptoms during the follow-up period was observed in five patients and was due to additional, newly developed atherosclerotic disease located distally, the bifurcation stents remaining patent. This new type of non-invasive procedure can be regarded a safe and efficous alternative to vascular surgery, especially in poor surgical candidates.
    Type of Medium: Electronic Resource
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