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  • Artikel  (3)
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  • Captopril
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  • Artikel  (3)
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  • 1
    Digitale Medien
    Digitale Medien
    Platelet Na+/H+ antiport activity in patients with insulin-dependent diabetes mellitus with and without diabetic nephropathy (1993)
    Springer
    Journal of molecular medicine 71 (1993), S. 119-125 
    Details
    ISSN: 1432-1440
    Schlagwort(e): Na+/H+ antiport ; Hypertension ; Diabetic nephropathy ; Hereditary factors
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary The incidence of diabetic nephropathy in patients with insulin-dependent diabetes mellitus (IDDM) may depend on factors other than the quality of diabetes control. Hypertension is an additional factor associated with a high degree of renal involvement in IDDM. One abnormality consistantly observed in various tissues of patients with essential hypertension is enhanced activity of the Na+/H+ antiport. In the present study we have therefore studied platelet antiport activity in 41 healthy subjects (control), in 22 patients with untreated essential hypertension (EH), and in 35 normotensive IDDM patients (type 1). Of these patients 17 exhibited signs of diabetic nephropathy (group 1) while 18 had no evidence for renal involvement of IDDM in spite of a duration of IDDM of at least 10 years (group 2). The two IDDM patient groups were undistinguishable with respect to age, body mass index, and arterial blood pressure (group 1, 117.9±2.4/78.4±1.5 mmHg; group 2, 113.9±3.6/76.1±1.8 mmHg). Antiporter activity was determined from the rate of cell volume changes induced by propionic acid. Platelet Na+/H+ exchange activity averaged 23.43±0.43 10−3·s−1 in control subjects and was markedly elevated in EH (28.38±0.62 10−3·s−1 P〈0.01). Antiport activity in group 2 patients without nephropathy averaged 24.54±0.57 10−3·s−1 and was undistinguishable from the control group. However, platelet Na+/H+ antiport activity was significantly stimulated in group 1 patients with nephropathy as compared to group 2(26.95±0.73 10−3. s−1 ; P〈0.025). Our results show that renal involvement in IDDM is associated with enhanced activity of the platelet Na+/H+ antiport.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00179992
    Standort Signatur Einschränkungen Verfügbarkeit
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  • 2
    Digitale Medien
    Digitale Medien
    64. Meßgenauigkeit und Störungen von Coriolis-Durchflußmessern bei pulsierender Fluidströmung (1993)
    Weinheim : Wiley-Blackwell
    Chemie Ingenieur Technik - CIT 65 (1993), S. 1088-1090 
    Details
    ISSN: 0009-286X
    Schlagwort(e): Chemistry ; Polymer and Materials Science
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Chemie und Pharmazie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/cite.330650966
    Standort Signatur Einschränkungen Verfügbarkeit
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  • 3
    Digitale Medien
    Digitale Medien
    Druckschwingungen durch oszillierende Verdrängerpumpen in RohrleitungssystemenVortrag von G. Vetter auf dem Jahrestreffen der Verfahrens-Ingenieure, 30. Sept. bis 2. Okt. 1992 in Wien. (1993)
    Weinheim : Wiley-Blackwell
    Chemie Ingenieur Technik - CIT 65 (1993), S. 677-692 
    Details
    ISSN: 0009-286X
    Schlagwort(e): Chemistry ; Polymer and Materials Science
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Chemie und Pharmazie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: Pressure Pulsations Caused by Reciprocating Pumps in Piping Systems. The safe design of piping installations for reciprocating pumps requires proper knowledge about the pump/installation interaction. In many cases critical resonance effects can be avoided by proper piping geometry or improved pump performance with respect to the volumetric efficiency (primary measures). Normally it is necessary to use various secondary dampening methods which can influence the acoustics of the piping system. Several examples of experimental computer simulations of damper action - upstream and downstream - are presented for fluidand gas-filled damper versions. The influence of entry geometry of the dampers is explained, hints on the proper geometry of the entries are given and the effects of various dampers and their influence on the total acoustics are discussed. Special reference is made to the effect of orifices as dissipative and acoustic elements in piping systems. The investigation shows the importance of analyzing of the total system of pump, piping installation and vessels or reactors and the application of computer simulation for piping design.
    Zusätzliches Material: 28 Ill.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/cite.330650603
    Standort Signatur Einschränkungen Verfügbarkeit
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