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  • 2010-2014
  • 1980-1984  (12)
  • 1983  (12)
  • 1
    Electronic Resource
    Electronic Resource
    Obesity, hypertension and intracellular electrolytes (1983)
    Springer
    Journal of molecular medicine 61 (1983), S. 803-805 
    Details
    ISSN: 1432-1440
    Keywords: Obesity ; Hypertension ; Intracellular sodium ; Intracellular calcium
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Intracellular activities of sodium and calcium were determined in red cells of patients with obesity. Compared to normal people mean intracellular sodium and calcium were higher in obese patients. However, increased intracellular sodium and calcium could only be observed in those patients with obesity suffering from hypertension or showing a familial disposition to hypertension. In contrast there was no difference in intracellular sodium and calcium between obese normotensives lacking a familial disposition to hypertension and normal people. Thus, our results suggest, that the observed variations in intracellular sodium and calcium in obesity are due to an enhanced blood pressure or a familial disposition to hypertension and not specific for obesity.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01496724
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  • 2
    Electronic Resource
    Electronic Resource
    Molecular specificity of the tubular resorption of “acidic” amino acids (1983)
    Springer
    Pflügers Archiv 396 (1983), S. 225-230 
    Details
    ISSN: 1432-2013
    Keywords: Kidney ; Tubular resorption ; Microperfusion ; Specificity ; Glutamate ; Aspartate ; Cysteate ; γ-Carboxyglutamate ; Pyroglutamate ; 5-oxo-proline
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Single sections of superficial proximal convolutions of rat kidney were microperfused in vivo and in situ. The perfusion fluids contained radioactively labelledl- ord-aspartate,l-glutamate,l-pyroglutamate, or N-methyl-d-aspartate.l-γ-Carboxyglutamate as well as the other amino acids were added in the unlabelled from. Results.l- andd-Aspartate (0.073 mmol·1−1) are quickly resorbed at about the same rate.d-Aspartate resorption was blocked byl-aspartate (5 mmol·1−1) but not by β-alanine (5 mmol·1−1).l-Aspartate resorption was inhibited byl-glutamate (2 mmol·1−1) but not byd-glutamate,l-asparagine,l-phenylalanine or by succinate (2 mmol·1−1, each). The fast resorption ofl-glutamate (0.073 mmol·1−1) was blocked byd-aspartate,l-cysteate (2 mmol·1−1), but not by 3-mercaptopicolinic acid (0.15 mmol·1−1),l-glutamine, 2-oxoglutarate, taurine, N-methyl-l-glutamate or kainic acid (2 mmol·1−1, each).l-γ-Carboxyglutamate (0.66 mmol·1−1) and N-methyl-d-aspartate (2μmol·1−1) were found to be resorbed only at an extremely small rate.l-pyroglutamate (0.076 mmol·1−1) resorption was not influenced byl-glutamate (1 mmol·1−1). Fractional excretion of γ-carboxyglutamate was 7–25% (l-from) or 45–70% (d-form) at an artificially elevated plasma level of 12μmol·1−1. It is concluded thatl- andd-aspartate,l-glutamate,l-cysteate and, to a much smaller extent,l-γ-carboxyglutamate, are accepted by the tubular resorption mechanism highly specific for “acidic” amino acids. N-Substitution, the amidation of the β- or γ-carboxyl group, or the removal of the α-amino moiety almost completely abolish the ability of such compounds to be resorbed via this carrier; N-methylated or γ-carboxylated derivatives of “acidic” amino acids are not resorbed at all from the proximal tubule. The resorption of glutamate, but not of aspartate, is highly stereospecific.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00587859
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  • 3
    Electronic Resource
    Electronic Resource
    The effect of glucose, tolbutamide, and arginine on C-peptide release during remission in type I diabetes mellitus (1983)
    Springer
    European journal of pediatrics 140 (1983), S. 305-310 
    Details
    ISSN: 1432-1076
    Keywords: Insulin dependent diabetes ; Remission ; Glucose ; Tolbutamide ; Arginine
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The insulin secretory capacity was examined in diabetic children at the time of partial clinical remission during which their condition could be managed with low insulin therapy (〈0.5 U insulin/kg body weight) and no urinary glucose excretion. The extent of the residual beta cell function in 26 children was assessed either by an i.v. arginine test, a combined i.v. glucose-i.v. arginine test, a combined i.v. tolbutamide-i.v. arginine test, or a combined oral glucose-i.v. arginine test determining the C-peptide response by calculating the area under the curve above baseline levels. Two of the children were tested repeatedly. Under the above conditions i.v. glucose and i.v. tolbutamide did not release C-peptide in diabetic children. In contrast, C-peptide secretion during arginine infusion following i.v. glucose or i.v. tolbutamide was siginficantly enhanced compared to the C-peptide secretion observed during arginine infusion alone. The C-peptide response to oral glucose was sluggish with no effect on the following arginine infusion. The results indicate that during remission in juvenile onset diabetes i.v. glucose and i.v. tolbutamide without themselves being an appropriate signal for C-peptide release amplify the response to a subsequent arginine infusion under appropriate conditions.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00442670
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  • 4
    Electronic Resource
    Electronic Resource
    Cadmium in finnish breast milk, a longitudinal study (1983)
    Springer
    Archives of toxicology 53 (1983), S. 207-211 
    Details
    ISSN: 1432-0738
    Keywords: Milk ; Human ; Cadmium
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Electrothermal atomic absorption spectrophotometry was employed to analyse cadmium in breast milk. Twenty breast milk samples were donated by seven mothers during 6 months of lactation. All milk samples represented every feeding during a period of 24 h, having foremilk an hindmilk in equal proportions. The median cadmium concentration in the 1st month was 2.0 μg/l (range 1.7–3.1 μg/l, 7 samples) and then declined to 1.5 μg/l (range 1.3–2.5 μg/l, 7 samples) and 1.6 μg/l (range 1.2–2.0 μg/l, 6 samples) in the 3rd and 6th months, respectively. At the age of 1 and 3 months when the infants were totally breast fed the average weekly intake of cadmium was 2.7 and 1.5 μg/kg. This is below the provisional tolerable weekly intake of man, from 6.7 to 8.3 μg/kg, proposed by WHO.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00316504
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  • 5
    Electronic Resource
    Electronic Resource
    Morphology, flow regimes, and filtering rates of Daphnia, Ceriodaphnia, and Bosmina fed natural bacteria (1983)
    Springer
    Oecologia 58 (1983), S. 156-163 
    Details
    ISSN: 1432-1939
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary Body size is the best overall indicator of the abilities of the cladocerans Daphnia magna, D. parvula, Ceriodaphnia lacustris and Bosmina longirostris to filter natural bacteria (〈1.0 μm). However, species differences exist which cannot be inferred from differences in size, behavior, or morphology alone. The relationship between filtering rate (FR in ml animal-1h-1) and body length (L in mm) for the cladocerans studied can be described by the power function: $$\begin{gathered} FR = 0.538 L^{1.545} \hfill \\ (r^2 = 0.88, F = 168.54, P 〈 0.001). \hfill \\ \end{gathered}$$ In D. parvula, algal filtering rates are higher and increase more rapidly with increasing body size than do bacterial filtering rates which are 26 to 33% of algal rates. This suggests that different processes may be involved in the capture of these ultrafine particles and that ultrafine particle capture efficiency decreases with increasing body size within a species. Weight specific filtering rates (in μl μg dry wt-1h-1) have a strong negative relationship to body size and show species specific differences. Appendage beat rates intersetular distances, setule diameter, appendage, area, % open space on the filtering appendage, Reynolds number, and boundary layer thickness do not provide simple predictions of bacterial filtering rates for the cladocerans studied. Filtering rates on cultured laboratory bacteria and algae may not indicate filtering rates on natural bacterioplankton because of differences in bacterial size, motility, and surface properties. Uptake of ultrafine particles may be enhanced by the presence of larger, more readily filtered particles through a “piggybacking” phenomenon.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00399211
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  • 6
    Electronic Resource
    Electronic Resource
    Stellenwert der modernen Krankenernährung in der medizinischen Praxis (1983)
    Springer
    European journal of nutrition 22 (1983), S. 241-254 
    Details
    ISSN: 1436-6215
    Keywords: Krankenernährung ; Organisation der Krankenernährung ; Ernährungsdiagnostik ; Ernährungskonzepte
    Source: Springer Online Journal Archives 1860-2000
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Medicine
    Description / Table of Contents: Summary Hospital diet is an essential part of modern therapy in all medical departments. It comprises both the so-called normal diets which are prepared according to modern nutritional knowledge, dietetic foods and the various forms of artificial nutrition (nutrient-defined and chemically defined diets, parenteral and combined nutrition, i.e. enterai and parenteral nutrition). The integration of nutritional therapeutic problems into the treatment of patients requires optimal scientific and practical forms of organisation of nutrition in the clinic. For that purpose, cooperation of clinical, technical, economic and pedagogic divisions is of prime importance. The organisation of patient nutrition in the St. Georg District Hospital in Leipzig is described as a feasible model.
    Notes: Zusammenfassung Die Krankenernährung ist ein wesentlicher Bestandteil einer modernen Therapie aller medizinischen Fachbereiche. Sie umfaßt sowohl die sogenannten Normalkostformen, die nach modernen ernährungswissenschaftlichen Kenntnissen hergestellt werden, die Diätkost und die verschiedenen Formen der künstlichen Ernährung (nährstoffdefinierte — und chemisch definierte Diäten, parenterale und Kombinationsernährung, d. h. enterai und parenteral). Die Einbeziehung der ernährungstherapeutischen Prinzipien in den Behandlungsplan der Patienten erfordert wissenschaftlich und praktisch optimale Organitionsformen der Krankenernährung. Dafür ist die Zusammenarbeit klinischer, technisch-wirtschaftlicher und pädagogischer Disziplinen Voraussetzung. Als praktikables Modell wird die Organisation der Krankenernährung im Bezirkskrankenhaus St. Georg Leipzig beschrieben.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02023857
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  • 7
    Electronic Resource
    Electronic Resource
    Häufigkeit und Bedeutung von Nierenarterienstenosen bei Patienten mit peripherer arterieller Verschlußkrankheit (1983)
    Springer
    Journal of molecular medicine 61 (1983), S. 339-342 
    Details
    ISSN: 1432-1440
    Keywords: Renal artery stenosis ; Hypertension ; Peripheral arterial occlusive disease
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary In order to evaluate the prevalence of renal artery stenoses and the coincidence with hypertension, in this study 110 patients (24 women, 86 men, mean age 63.2±8.6 years) underwent retrograde aortography for reason of symptomatic arteriosclerosis obliterans of the lower limb arteries. In 18 (16.4%) patients renal artery stenoses by which the lumen was narrowed for more than 30% and in 2 (1.8%) patients occlusions of one renal artery were found, all of which seemed to be of arteriosclerotic origin. 12 (60%) patients with renal artery stenoses or occlusions showed arterial hypertension (RR 171±33/94±16 mmHg) inspite of adequate antihypertensive medication, 8 were normotensive even though renal artery stenoses were found angiographically. On the other hand 30 (33%) of the 90 patients without renal artery stenoses were hypertensive (RR 165±15/93±9 mmHg). These data support the observation that renal artery stenoses must not result in hypertension, but clearly indicate the higher prevalence of hypertension in patients with renal artery stenoses or occlusions. With regard to the low-risk procedure of percutaneous transluminal dilatation of renal arteries, it seems to be valuable for hypertensive patients to include renovasography into the angiographic evaluation of symptomatic lower limb arteriosclerosis.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01485024
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  • 8
    Electronic Resource
    Electronic Resource
    Intracellular Na+ and Ca2+ in aortic smooth muscle cells after enzymatic isolation in spontaneously hypertensive rats (1983)
    Springer
    Research in experimental medicine 183 (1983), S. 129-132 
    Details
    ISSN: 1433-8580
    Keywords: Intracellular Na+ and Ca2+ ; Aortic smooth muscle ; Spontaneously hypertensive rats
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary In aortic smooth muscle cells from spontaneously hypertensive and normotensive rats, which were separated from the blood vessels by enzymatic digestion, intracellular Na+ and Ca2+ activities were measured. The determinations were made by ion-selective electrodes. In smooth muscle cells from spontaneously hypertensive rats intracellular Na+ and Ca2+ activities were elevated as compared to cells from normotensive rats (P〈0.001 for Na+ andP〈0.01 for Ca2+). Since in cultured aortic smooth muscle cells from spontaneously hypertensive rats intracellular Ca2+ is known to be not significantly increased, primarily humoral factors may account for the changes in intracellular Ca2+ reported.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01851778
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  • 9
    Electronic Resource
    Electronic Resource
    Potassium load in spontaneously hypertensive rats. Effects on blood pressure, renin-angiotensin, aldosterone, and intracellular electrolytes (1983)
    Springer
    Research in experimental medicine 183 (1983), S. 147-152 
    Details
    ISSN: 1433-8580
    Keywords: Potassium ; Blood pressure ; Intracellular electrolytes
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary To study the mechanisms by which K+ influences vascular tone in hypertension, spontaneously hypertensive and normotensive rats were examined during an oral K+ load. There was a marked decrease in blood pressure in spontaneously hypertensive but not in normotensive rats. Intraerythrocytic K+ concentration and activity increased in normotensive but not in spontaneously hypertensive rats. Intraerythrocytic Na+ concentration and activity declined in both strains, the decrease in Na+ activity being more prominent in spontaneously hypertensive rats (P〈0.05). Intraerythrocytic Ca2+ activity decreased in spontaneously hypertensive rats (P〈0.01) but not in normotensive rats. In both strains plasma aldosterone concentration increased during K+ load, the plasma renin activity being suppressed. The basal levels of plasma aldosterone in spontaneously hypertensive rats exceeded those in normotensive rats. It is concluded that intraerythrocytic Ca2+, and to a lesser extent Na+, correlate best with the blood pressure changes. These ionic changes may be mediated by hormonal factors. The significance of the elevated plasma aldosterone levels has not yet been entirely clarified.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01851781
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  • 10
    Electronic Resource
    Electronic Resource
    Behavioral responses of maleHeliothis virescens in a sustained-flight tunnel to combinations of seven compounds identified from female sex pheromone glands (1983)
    Springer
    Journal of chemical ecology 9 (1983), S. 747-759 
    Details
    ISSN: 1573-1561
    Keywords: Tobacco budworm ; Heliothis virescens ; Lepidoptera ; Noctuidae ; flight tunnel ; sex pheromone ; moth behavior ; rubber septa
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology
    Notes: Abstract Each of the seven compounds that have been identified from femaleHeliothis virescens sex pheromone glands was examined for its ability to elicit sexual responses from male moths in a flight tunnel. The two compounds initially described as pheromone components, (itZ)-11-hexadecenal and (itZ)-9-tetradecenal, were necessary for behavioral activity to occur. Of the remaining five compounds, hexadecanal was most consistent in elevating behavioral activity of males when it was added to treatments. Live, calling females elicited greater sexual activity from males than did the 7-compound mixture on rubber septa.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00988780
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