In:
Journal of Magnetic Resonance Imaging, Wiley, Vol. 45, No. 4 ( 2017-04), p. 1055-1067
Abstract:
To define reference values of cardiac volumes, dimensions, and new morpho‐functional parameters normalized for age, gender, and body surface area by cine‐bSSFP (balanced steady‐state free‐precession) magnetic resonance (MR). Materials and Methods We enrolled 308 healthy subjects subdivided by gender and by six age classes: class I, 〉 15–20 years; class II, 〉 20–30 years; class III, 〉 30–40 years; class IV, 〉 40–50 years; class V, 〉 50–60 years; and class VI 〉 60 years. Dimensional, volumetric and morpho‐functional parameters of the left (LV) and right (RV) ventricles were measured using cine‐bSSFP MRI at 1.5T. Results The LV and RV end‐diastolic volume indexes (EDVi) were inversely related to age ( P 〈 0.0001 r = –0.34 and P 〈 0.0001 r = –0.37, respectively). In addition, the LV mass index decreased with age ( P = 0.0004, r = –0.21). The LV longitudinal shortening was not significantly different among groups: ≥15% in all populations (95% confidence interval [CI]: 16–31). The sphericity index measured in end‐diastole was higher in females than in males ( P 〈 0.03): the upper limit was 40% for males and 42% for females. The normality cutoff of LV global function index was ≥33% in males and ≥35% in females. The end‐diastolic volume (EDV) of RV and LV was balanced (RV/LV ratio 0.85–1.15) without differences in the population. The LV EDV/mass was 1.0–1.8 in males and 1.0–2.1 in females. Conclusion This study provides potential age‐ and gender‐specific reference. Level of Evidence: 2 J. Magn. Reson. Imaging 2017;45:1055–1067
Type of Medium:
Online Resource
ISSN:
1053-1807
,
1522-2586
Language:
English
Publisher:
Wiley
Publication Date:
2017
detail.hit.zdb_id:
1497154-9
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