In:
Digestion, S. Karger AG, Vol. 97, No. 3 ( 2018), p. 219-227
Abstract:
〈 b 〉 〈 i 〉 Background and Aims: 〈 /i 〉 〈 /b 〉 We aimed to investigate an association between clinicopathological features, including immunohistochemical mucin phenotypes, and magnifying chromoendoscopic findings with crystal violet staining (ME-CV) in non-ampullary duodenal epithelial tumors (NADETs). 〈 b 〉 〈 i 〉 Methods: 〈 /i 〉 〈 /b 〉 A total of 55 patients with NADET were divided into 3 groups by mucin phenotype: intestinal, gastrointestinal, or gastric. ME-CV findings were classified into 4 patterns: convoluted, leaf-like, reticular/sulciolar, and pinecone. The clinicopathological features and ME-CV findings were compared among the mucin phenotypes. 〈 b 〉 〈 i 〉 Results: 〈 /i 〉 〈 /b 〉 Tumors of the gastric type were located in the duodenal bulb ( 〈 i 〉 p 〈 /i 〉 & #x3c; 0.001), and contained pyloric gland adenoma ( 〈 i 〉 p 〈 /i 〉 & #x3c; 0.001) more frequently than the other types. White-light endoscopy indicated that milk-white mucosa was less frequent in tumors of the gastric type than in those of the gastrointestinal type ( 〈 i 〉 p 〈 /i 〉 = 0.006) and the intestinal type ( 〈 i 〉 p 〈 /i 〉 & #x3c; 0.001). ME-CV findings were significantly different between the gastric type and the other type ( 〈 i 〉 p 〈 /i 〉 = 0.028). Totally, 5 of 8 tumors of the gastric type manifested a pinecone pattern, 4 of which were compatible with pyloric gland adenoma. 〈 b 〉 〈 i 〉 Conclusions: 〈 /i 〉 〈 /b 〉 The endoscopic findings of NADETs differ according to mucin phenotype. A pinecone pattern under ME-CV may be characteristic of NADETs of the gastric type, especially pyloric gland adenoma.
Type of Medium:
Online Resource
ISSN:
0012-2823
,
1421-9867
Language:
English
Publisher:
S. Karger AG
Publication Date:
2018
detail.hit.zdb_id:
1482218-0
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