ISSN:
1574-6968
Source:
Blackwell Publishing Journal Backfiles 1879-2005
Topics:
Biology
Notes:
Abstract The HSP70 genes of eukaryotes show up to 50% nucleotide sequence homology to the dnaK gene of Escherichia coli. This extreme structure conservation implies conservation of a function that may be needed by all cells, suggesting that other bacteria may have sequences related to HSP70 and dnaK. Amongst other functions, HSP70-like proteins may act to limit thermal protein denaturation. In this study DNA isolated from thermophilic archaebacteria (from the family Desulfurococcus) and thermophilic eubacteria (from the families Bacillus and Thermus) was probed with sequences from a heat shock inducible HSP70 gene of the yeast Saccharomyces cerevisiae. Hybridization was detected under conditions of low stringency, indicating the existence of HSP70-related sequences in the thermophilic bacteria studied.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1111/j.1574-6968.1988.tb03169.x
