Publication Date:
2018-03-09
Description:
A procedure for preparing 1-(2-hydroxy-3-[ 18 F]fluoropropyl)-2-nitroimidazole ([ 18 F]fluoromisonidazole, [ 18 F]FMISO) on a commercially available GE TracerLAB Fx F-N synthesis module was developed. The product obtained meets all the requirements of the European Pharmacopoeia (8th ed.) for clinical use. Its decay-corrected radiochemical yield is 59 ± 4% ( n = 5).
Print ISSN:
1066-3622
Electronic ISSN:
1608-3288
Topics:
Chemistry and Pharmacology