Publication Date:
2016-01-15
Description:
Article Drosophila RNAi libraries are commonly used to perform large-scale functional genetics screens in vivo . Here the authors find that a subset of lines from the VDRC KK RNAi line cause false-positive enhancement of the Hippo pathway, and provide a strain that can test whether a genetic screen of interest will be affected by this technical artefact. Nature Communications doi: 10.1038/ncomms10368 Authors: Joseph H.A. Vissers, Samuel A. Manning, Aishwarya Kulkarni, Kieran F. Harvey
Electronic ISSN:
2041-1723
Topics:
Biology
,
Chemistry and Pharmacology
,
Natural Sciences in General
,
Physics