GLORIA — GEOMAR Library Ocean Research Information Access

Hits per page

hit 1 - 1 | 1 hit

Select All Export

Electronic Resource

Chronokinetic study of netilmicin in man (1990)

Lucht, F. ; Tigaud, S. ; Esposito, G. ; [et al.]

Springer

European journal of clinical pharmacology 39 (1990), S. 199-201

add to mindlist on the mindlist

Details

ISSN: 1432-1041

Keywords: netilmicin ; pharmacokinetics ; diurnal variation ; circadian rhythm

Source: Springer Online Journal Archives 1860-2000

Topics: Chemistry and Pharmacology , Medicine

Notes: Summary Netilmicin 1.5 mg/kg body weight was administered intravenously every 8 h for 2 days to 8 patients with normal renal function. Significant elevation of mean and trough plasma concentrations was found at 05.00 h and 09.00 h. This was considered to be due to circadian variation, with possible accumulation during the night. The clinical importance of this phenomenon in relation to the development of aminoglycoside toxicity awaits further investigation.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1007/BF00280062

	Location	Call Number	Limitation	Availability

Others were also interested in ...

Paper (German National Licenses)

Fulltext

hit 1 - 1 | 1 hit