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  • Articles  (5)
  • Surface physics, nanoscale physics, low-dimensional systems  (3)
  • *Gene Expression Regulation  (1)
  • Arrhythmias, Catheter Ablation and Implantable Cardioverter-Defibrillator, Electrophysiology, Quality and Outcomes  (1)
  • 1
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    Hole-spin pumping and repumping in a p-type δ-doped InAs quantum dot (2014)
    American Physical Society (APS)
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    Publication Date: 2014-09-16
    Description: Author(s): Konstantinos G. Lagoudakis, Kevin A. Fischer, Tomas Sarmiento, Kai Mueller, and Jelena Vučković We have grown high quality p-type δ-doped InAs quantum dots and have demonstrated coherent spin pumping and repumping of a hole spin in a positively charged quantum dot by means of a single-laser driving scheme under a high magnetic field in the Voigt configuration. Modeling of our system shows exce... [Phys. Rev. B 90, 121402] Published Mon Sep 15, 2014
    Keywords: Surface physics, nanoscale physics, low-dimensional systems
    Print ISSN: 1098-0121
    Electronic ISSN: 1095-3795
    Topics: Physics
    Published by American Physical Society (APS)
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  • 2
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    Optical near-field interference in the excitation of a bowtie nanoantenna (2011)
    American Physical Society (APS)
    Details
    Publication Date: 2011-06-09
    Description: Author(s): P. Melchior, D. Bayer, C. Schneider, A. Fischer, M. Rohmer, W. Pfeiffer, and M. Aeschlimann We show experimentally as well as in simulation that the phase-sensitive superposition of different plasmonic modes leads to a spatially controllable enhancement of the near-field inside and in the vicinity of a metallic nanostructure. Multiphoton photoemission electron microscopy maps the local nea... [Phys. Rev. B 83, 235407] Published Wed Jun 08, 2011
    Keywords: Surface physics, nanoscale physics, low-dimensional systems
    Print ISSN: 1098-0121
    Electronic ISSN: 1095-3795
    Topics: Physics
    Published by American Physical Society (APS)
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  • 3
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    Dissipative preparation of the exciton and biexciton in self-assembled quantum dots on picosecond time scales (2014)
    American Physical Society (APS)
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    Publication Date: 2014-12-03
    Description: Author(s): Per-Lennart Ardelt, Lukas Hanschke, Kevin A. Fischer, Kai Müller, Alexander Kleinkauf, Manuel Koller, Alexander Bechtold, Tobias Simmet, Jakob Wierzbowski, Hubert Riedl, Gerhard Abstreiter, and Jonathan J. Finley Pulsed resonant fluorescence is used to probe ultrafast phonon-assisted exciton and biexciton preparation in individual self-assembled InGaAs quantum dots. By driving the system using large area (≥10π) near resonant optical pulses, we experimentally demonstrate how phonon-mediated dissipation within... [Phys. Rev. B 90, 241404] Published Tue Dec 02, 2014
    Keywords: Surface physics, nanoscale physics, low-dimensional systems
    Print ISSN: 1098-0121
    Electronic ISSN: 1095-3795
    Topics: Physics
    Published by American Physical Society (APS)
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  • 4
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    Trends in Use and Adverse Outcomes Associated with Transvenous Lead Removal in the United States [Arrhythmia/Electrophysiology] (2015)
    American Heart Association (AHA)
    Details
    Publication Date: 2015-12-24
    Description: Background— Transvenous lead removal (TLR) has made significant progress with respect to innovation, efficacy, and safety. However, limited data exist regarding trends in use and adverse outcomes outside the centers of considerable experience for TLR. The aim of our study was to examine use patterns, frequency of adverse events, and influence of hospital volume on complications. Methods and Results— Using the Nationwide Inpatient Sample, we identified 91 890 TLR procedures. We investigated common complications including pericardial complications (hemopericardium, cardiac tamponade, or pericardiocentesis), pneumothorax, stroke, vascular complications (consisting of hemorrhage/hematoma, incidents requiring surgical repair, and accidental arterial puncture), and in-hospital deaths described with TLR, defining them by the validated International Classification of Diseases, Ninth Revision, Clinical Modification diagnosis code. We specifically assessed in-hospital death (2.2%), hemorrhage requiring transfusion (2.6%), vascular complications (2.0%), pericardial complications (1.4%), open heart surgery (0.2%), and postoperative respiratory failure (2.4%). Independent predictors of complications were female sex and device infections. Hospital volume was not independently associated with higher complications. There was a significant rise in overall complication rates over the study period. Conclusions— The overall complication rate in patients undergoing TLR was higher than previously reported. Female sex and device infections are associated with higher complications. Hospital volume was not associated with higher complication rates. The number of adverse events in the literature likely underestimates the actual number of complications associated with TLR.
    Keywords: Arrhythmias, Catheter Ablation and Implantable Cardioverter-Defibrillator, Electrophysiology, Quality and Outcomes
    Electronic ISSN: 1524-4539
    Topics: Medicine
    Published by American Heart Association (AHA)
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  • 5
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    MicroRNA-34a regulates cardiac ageing and function (2013)
    Nature Publishing Group (NPG)
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    Publication Date: 2013-02-22
    Description: Ageing is the predominant risk factor for cardiovascular diseases and contributes to a significantly worse outcome in patients with acute myocardial infarction. MicroRNAs (miRNAs) have emerged as crucial regulators of cardiovascular function and some miRNAs have key roles in ageing. We propose that altered expression of miRNAs in the heart during ageing contributes to the age-dependent decline in cardiac function. Here we show that miR-34a is induced in the ageing heart and that in vivo silencing or genetic deletion of miR-34a reduces age-associated cardiomyocyte cell death. Moreover, miR-34a inhibition reduces cell death and fibrosis following acute myocardial infarction and improves recovery of myocardial function. Mechanistically, we identified PNUTS (also known as PPP1R10) as a novel direct miR-34a target, which reduces telomere shortening, DNA damage responses and cardiomyocyte apoptosis, and improves functional recovery after acute myocardial infarction. Together, these results identify age-induced expression of miR-34a and inhibition of its target PNUTS as a key mechanism that regulates cardiac contractile function during ageing and after acute myocardial infarction, by inducing DNA damage responses and telomere attrition.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Boon, Reinier A -- Iekushi, Kazuma -- Lechner, Stefanie -- Seeger, Timon -- Fischer, Ariane -- Heydt, Susanne -- Kaluza, David -- Treguer, Karine -- Carmona, Guillaume -- Bonauer, Angelika -- Horrevoets, Anton J G -- Didier, Nathalie -- Girmatsion, Zenawit -- Biliczki, Peter -- Ehrlich, Joachim R -- Katus, Hugo A -- Muller, Oliver J -- Potente, Michael -- Zeiher, Andreas M -- Hermeking, Heiko -- Dimmeler, Stefanie -- England -- Nature. 2013 Mar 7;495(7439):107-10. doi: 10.1038/nature11919. Epub 2013 Feb 20.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Institute for Cardiovascular Regeneration, Centre of Molecular Medicine, Goethe University Frankfurt, 60590 Frankfurt, Germany.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/23426265" target="_blank"〉PubMed〈/a〉
    Keywords: Aging/genetics/pathology/*physiology ; Animals ; Apoptosis ; DNA Damage ; Fibrosis/genetics/pathology ; Gene Deletion ; *Gene Expression Regulation ; Gene Knockout Techniques ; Genetic Therapy ; Heart/*physiology ; Mice ; Mice, Inbred C57BL ; MicroRNAs/*genetics/metabolism ; Myocardial Infarction/genetics/pathology/therapy ; Myocardium/cytology/*metabolism/pathology ; Myocytes, Cardiac/cytology/metabolism/pathology ; Substrate Specificity ; Telomere/genetics/metabolism
    Print ISSN: 0028-0836
    Electronic ISSN: 1476-4687
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Published by Nature Publishing Group (NPG)
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