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  • 1
    Online Resource
    Online Resource
    Berlin, Heidelberg :Springer Berlin / Heidelberg,
    Keywords: Proteins-Structure-Congresses. ; Electronic books.
    Type of Medium: Online Resource
    Pages: 1 online resource (141 pages)
    Edition: 1st ed.
    ISBN: 9783642741739
    Series Statement: Colloquium der Gesellschaft Für Biologische Chemie in Mosbach Baden Series ; v.39
    DDC: 574.19245
    Language: English
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  • 2
    Online Resource
    Online Resource
    San Diego :Elsevier Science & Technology,
    Keywords: Genetics. ; Electronic books.
    Type of Medium: Online Resource
    Pages: 1 online resource (307 pages)
    Edition: 1st ed.
    ISBN: 9780123808592
    Series Statement: Issn Series
    DDC: 573.8
    Language: English
    Note: Front Cover -- Aggression -- Copyright -- Contents -- Contributors -- Chapter 1: Aggression -- Chapter 2: Evolutionary Aspects of Aggression: The Importance of Sexual Selection -- I. Introduction -- II. Sexual Selection -- III. Mating Systems -- IV. When to Fight and When to Flee -- V. Case Studies: Sexual Dimorphism -- VI. Humans and the Mammalian Pattern -- Acknowledgment -- References -- Chapter 3: Signaling Aggression -- I. Introduction -- A. An ethological approach to aggression -- B. The classic game theory model -- C. Signaling games -- D. Threat displays and why they are part of aggression -- E. Evolutionary issues -- F. The challenge of "incomplete honesty -- G. Case studies in aggressive signaling -- II. Bird Song Signals Aggressive Intentions: Speak Softly and Carry a Big Stick -- III. Visual Displays Signal Aggressive Intent in Cephalopods: The Sweet Smell of Success -- A. Cuttlefish agonistic bouts -- B. Squid agonistic bouts -- C. From molecules to aggression: Contact pheromone triggers strong aggression in squid -- D. Signaling aggression in humans -- Acknowledgments -- References -- Chapter 4: Self-Structuring Properties of Dominance Hierarchies... -- I. Introduction -- II. Definitions -- A. Dominance relationships -- B. Dominance hierarchies -- III. Animal Models -- A. Chickens -- B. Fish -- C. Crustaceans -- D. Primates -- IV. Factors Affecting Dominance Relationships in Pairs of Animals -- A. Physical differences -- 1. Behavioral profile or personality -- B. Physiology -- C. Genetics -- D. Behavioral states: Winner, loser and bystander effects -- V. Formation of Dominance Relationships and Dominance Hierarchies in Groups -- A. Differences in individual attributes and hierarchy formation -- B. Influence of social factors on linear hierarchy formation. , VI. A New Approach to Explaining the Formation of Linear Hierarchies: Behavioral Processes -- A. Modifications of the jigsaw puzzle model -- B. Experimental evidence concerning animal cognitive abilities and processes of interaction -- VII. Conclusion -- Acknowledgments -- References -- Chapter 5: Neurogenomic Mechanisms of Aggression in Songbirds -- I. Aggression in Context -- II. Hormonal Mechanisms of Aggression -- A. Territoriality in the breeding season -- B. Hormones and territoriality -- C. Aggression outside the breeding season -- 1. Aggression in flocks -- 2. Territoriality in the nonbreeding season -- D. Evolution of aggression and life history strategies -- III. Transcriptional Activity and Neural Mechanisms of Aggression in Birds -- A. Transcriptional traces of aggression reveal ubiquitous vertebrate themes -- B. Neurochemistry and major modulators -- IV. A Natural Model Uniting Social Behavior, Hormones, and Genetics -- A. The white-throated sparrow -- B. Endocrine and neuroendocrine correlates of behavioral polymorphism -- C. Causality and "phenotypic engineering -- D. Mapping the ZAL2m -- V. Future Directions -- Acknowledgments -- References -- Chapter 6: Genetics of Aggression in Voles -- I. Introduction -- II. The Prairie Vole Model -- III. Neural Correlates -- IV. Neural Circuitry -- V. Neurochemical Regulation of Selective Aggression -- A. Neuropeptides -- B. Dopamine -- C. Steroid hormones -- D. Classical neurotransmitters -- VI. Molecular Genetics of Selective Aggression -- VII. Drug-induced Aggression -- VIII. Conclusions and Future Directions -- Acknowledgments -- References -- Chapter 7: The Neurochemistry of Human Aggression -- I. Introduction -- II. Serotonin -- III. Dopamine -- IV. Norepinephrine (Noradrenaline) -- V. GABA -- VI. Peptides -- VII. Conclusion -- References -- Chapter 8: Human Aggression Across the Lifespan. , I. Heritability of Aggression: Twin and Adoption Studies -- A. Does heritability vary depending on sex? -- B. Does heritability change across age? -- C. Do heritabilities vary across methods of assessment? -- D. Do heritabilities vary across forms of aggression? -- E. Does heritability vary depending on study design (twins vs. adopted siblings)? -- F. Criticisms of twin and adoption studies: Assumptions and generalizability -- II. G x E Interaction in Aggressive Behavior -- A. Potential moderators of genetic influence found in adoption and twin studies -- 1. Family adversity and social disadvantage -- 2. Violent media exposure -- 3. Alcohol use -- III. Specific Genes for Aggressive Behavior: Findings from Molecular Genetic Studies -- A. G x E interaction involving specific genes for aggressive behavior -- IV. Conclusions -- References -- Chapter 9: Perinatal Risk Factors in the Development of Aggression and Violence -- I. Introduction -- II. The Neurobiological and Psychophysiological Systems Involved in the Regulation of Aggression and Violence -- A. Types of aggressive behavior -- B. Neurobiological bases of aggression and violence -- 1. Amygdala -- 2. Anterior cingulate cortex -- 3. Prefrontal cortex -- 4. Hypothalamus -- C. Neurochemical signals of aggression and violence -- 1. Neurotransmitters-serotonin -- 2. Neurotransmitters-dopamine -- 3. Neurotransmitters-norepinephrine -- D. Hormones -- 1. Testosterone -- 2. Cortisol -- 3. Oxytocin -- E. Autonomic response measures -- 1. Heart rate and electrodermal activity -- F. Electro cortical response measures -- III. Perinatal Factors Related to the Development of Aggression -- A. Birth complications -- B. Preterm birth and low birth weight -- C. Prenatal drug and alcohol exposure -- 1. Alcohol -- 2. Drugs -- D. Smoking -- E. Maternal psychological stress -- F. Environmental context. , IV. Genetic Contributions -- A. Genetic factors as explanatory -- B. Gene by environment (G x E) interactions -- 1. Monoamine oxidase genotype -- 2. Genes related to dopaminergic function -- 3. Catechol O-methyltransferase -- C. The role of epigenetics -- V. Conclusions -- References -- Chapter 10: Neurocriminology -- I. Introduction -- II. Psychodynamic Theories -- III. Neuroimaging -- A. Structural imaging studies -- B. Functional imaging studies -- IV. Neuropsychological Testing -- V. Psychophysiological Evidence -- A. Electrocortical measures -- 1. Electroencephalogram (EEG) -- 2. Event-related potentials (ERPs) -- 3. Low resting heart rate -- 4. Skin conductance -- VI. Genetics -- A. Twin studies -- B. Adoption studies -- C. Molecular genetics -- D. ACE model -- E. Gene-environment interaction -- VII. Nongenetic Risk Factors -- A. Prenatal -- 1. Minor physical anomalies (MPAs) -- 2. Tobacco -- 3. Alcohol -- B. Perinatal risk factors -- C. Postnatal -- 1. Traumatic brain injury (TBI) -- VIII. The Limitations and Potential of Neurocriminology -- IX. Modifiable Risk Factor Interventions -- X. Conclusion -- References -- Index -- Colour Plate.
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  • 3
    Type of Medium: Book
    Pages: 103, 24 Blätter , graphische Darstellungen
    Language: English
    Note: Bremen, Universität, Dissertation, 1999
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  • 4
    Keywords: Forschungsbericht ; Fertigbauteil ; Recycling ; Bauökologie ; Nachhaltigkeit ; Berufliche Fortbildung
    Type of Medium: Online Resource
    Pages: Online-Ressource (109 Seiten, 11,8 MB) , Illustrationen, Diagramme
    Language: German
    Note: Unterschiede zwischen dem gedruckten Dokument und der elektronischen Ressource können nicht ausgeschlossen werden
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  • 5
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    The @journal of organic chemistry 57 (1992), S. 5778-5780 
    ISSN: 1520-6904
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 6
    ISSN: 1520-4995
    Source: ACS Legacy Archives
    Topics: Biology , Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    Biochemistry 26 (1987), S. 5153-5162 
    ISSN: 1520-4995
    Source: ACS Legacy Archives
    Topics: Biology , Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Palo Alto, Calif. : Annual Reviews
    Annual Review of Biophysics and Biomolecular Structure 28 (1999), S. 295-317 
    ISSN: 1056-8700
    Source: Annual Reviews Electronic Back Volume Collection 1932-2001ff
    Topics: Biology , Physics
    Notes: Abstract Proteasomes are large multisubunit proteases that are found in the cytosol, both free and attached to the endoplasmic reticulum, and in the nucleus of eukaryotic cells. Their ubiquitous presence and high abundance in these compartments reflects their central role in cellular protein turnover. Proteasomes recognize, unfold, and digest protein substrates that have been marked for degradation by the attachment of a ubiquitin moiety. Individual subcomplexes of the complete 26S proteasome are involved in these different tasks: The ATP-dependent 19S caps are believed to unfold substrates and feed them to the actual protease, the 20S proteasome. This core particle appears to be more ancient than the ubiquitin system. Both prokaryotic and archaebacterial ancestors have been identified. Crystal structures are now available for the E. coli proteasome homologue and the T. acidophilum and S. cerevisiae 20S proteasomes. All three enzymes are cylindrical particles that have their active sites on the inner walls of a large central cavity. They share the fold and a novel catalytic mechanism with an N-terminal nucleophilic threonine, which places them in the family of Ntn (N terminal nucleophile) hydrolases. Evolution has added complexity to the comparatively simple prokaryotic prototype. This minimal proteasome is a homododecamer made from two hexameric rings stacked head to head. Its heptameric version is the catalytic core of archaebacterial proteasomes, where it is sandwiched between two inactive antichambers that are made up from a different subunit. In eukaryotes, both subunits have diverged into seven different subunits each, which are present in the particle in unique locations such that a complex dimer is formed that has six active sites with three major specificities that can be attributed to individual subunits. Genetic, biochemical, and high-resolution electron microscopy data, but no crystal structures, are available for the 19S caps. A first step toward a mechanistic understanding of proteasome activation and regulation has been made with the elucidation of the X-ray structure of the alternative, mammalian proteasome activator PA28.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    Langmuir 3 (1987), S. 827-830 
    ISSN: 1520-5827
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 10
    ISSN: 1520-4995
    Source: ACS Legacy Archives
    Topics: Biology , Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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