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  • 1
    Electronic Resource
    Electronic Resource
    High dose bolus methylprednisolone for the treatment of acute graft versus host disease (1983)
    Springer
    Annals of hematology 46 (1983), S. 125-132 
    Details
    ISSN: 1432-0584
    Keywords: Graft versus host disease ; Methylprednisolone
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Nineteen patients with acute graft versus host disease (GvHD) following bone marrow transplantation (BMT) were treated with high dose bolus 6-methylprednisolone (BMPr), at the dose of 20 mg/kg/day i.v. for the first 3 days, 10 mg/kg/day i.v. for the following 4 days, and then at doses gradually tapered down to 1 mg/kg/day. All patients except one, who was given preventive BMPr 5 mg/kg/day i.v. on alternate days, were placed on preventive methotrexate therapy after BMT. Sixteen patients were grafted with an HLA matched, and three patients with an HLA mismatched marrow. Overall complete response rate in the HLA matched group was 43%, with an additional 50% showing a partial response. In the HLA mismatched group there were no responses and all three patients proved refractory to BMPr. With respect to organ involvement the complete and partial response rates were respectively 50% and 33% in the skin, 36% and 28% in the liver, 18% and 55% in the gut. Six of sixteen patients in the HLA matched group and none of the three in the HLA mismatched group are surviving. Thirteen patients died: nine patients for causes directly or indirectly related to GvHD, four of other causes (relapse, rejection, hemorrhage and idiopathic interstitial pneumonia). Side effects of BMPr consisted in hyperglicemia, and steroid associated gastritis in 2/3 of the patients, both of which responded well to conventional treatment. This study indicates that high dose BMPr is an effective form of treatment for established acute GvHD, and has no major side effects. The efficacy of BMPr is less clear in recipients of HLA mismatched grafts.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00320270
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    Paper (German National Licenses)
    Fulltext
  • 2
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    (Table 4) Seasonal variation of sea spray sodium concentrations during 2004-2007 at Concordia Station, Antarctica (2012)
    PANGAEA
    In:  Supplement to: Udisti, Roberto; Dayan, Uri; Becagli, Silvia; Busetto, Maurizio; Frosini, Daniele; Legrand, Michel R; Lucarelli, F; Preunkert, Suzanne; Severi, Mirko; Traversi, Rita; Vitale, Vito (2012): Sea spray aerosol in central Antarctica. Present atmospheric behaviour and implications for paleoclimatic reconstructions. Atmospheric Environment, 52, 109-120, https://doi.org/10.1016/j.atmosenv.2011.10.018
    Details
    Publication Date: 2023-12-13
    Description: From November 2004 to December 2007, size-segregated aerosol samples were collected all-year-round at Dome C (East Antarctica) by using PM10 and PM2.5 samplers, and multi-stage impactors. The data set obtained from the chemical analysis provided the longest and the most time-resolved record of sea spray aerosol (sea salt Na+) in inner Antarctica. Sea spray showed a sharp seasonal pattern. The highest values measured in winter (Apr-Nov) were about ten times larger than in summer (Dec-Mar). For the first time, a size-distribution seasonal pattern was also shown: in winter, sea spray particles are mainly submicrometric, while their summer size-mode is around 1-2 µm. Meteorological analysis on a synoptic scale allowed the definition of atmospheric conditions leading sea spray to Dome C. An extreme-value approach along with specific environmental based criteria was taken to yield stronger fingerprints linking atmospheric circulation (means and anomalies) to extreme sea spray events. Air mass back-trajectory analyses for some high sea spray events allowed the identification of two major air mass pathways, reflecting different size distributions: micrometric fractions for transport from the closer Indian-Pacific sector, and sub-micrometric particles for longer trajectories over the Antarctic Plateau. The seasonal pattern of the SO4**2- /Na+ ratio enabled the identification of few events depleted in sulphate, with respect to the seawater composition. By using methanesulphonic acid (MSA) profile to evaluate the biogenic SO4**2- contribution, a more reliable sea salt sulphate was calculated. In this way, few events (mainly in April and in September) were identified originating probably from the "frost flower" source. A comparison with daily-collected superficial snow samples revealed that there is a temporal shift between aerosol and snow sea spray trends. This feature could imply a more complex deposition processes of sea spray, involving significant contribution of wet and diamond dust deposition, but further work has to be carried out to rule out the effect of wind re-distribution and to have more statistic significance.
    Keywords: DATE/TIME; Date/time end; Dome C, Antarctica; International Polar Year (2007-2008); IPY; MULT; Multiple investigations; Season; Sodium; Sodium, standard deviation; Station_Concordia
    Type: Dataset
    Format: text/tab-separated-values, 42 data points
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  • 3
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    Basic measurements of radiation at Concordia Station (2006-01) (2009)
    PANGAEA
    In:  Institute of Atmospheric Sciences and Climate of the Italian National Research Council, Bologna
    Details
    Publication Date: 2024-01-25
    Keywords: Antarctica; Baseline Surface Radiation Network; BSRN; Concordia Station, Dome C; DATE/TIME; Diffuse radiation; Diffuse radiation, maximum; Diffuse radiation, minimum; Diffuse radiation, standard deviation; Direct radiation; Direct radiation, maximum; Direct radiation, minimum; Direct radiation, standard deviation; DOM; HEIGHT above ground; Long-wave downward radiation; Long-wave downward radiation, maximum; Long-wave downward radiation, minimum; Long-wave downward radiation, standard deviation; Monitoring station; MONS; Pyranometer, Kipp & Zonen, CM22, SN 050108, WRMC No. 74002; Pyranometer, Kipp & Zonen, CM22, SN 050110, WRMC No. 74001; Pyrgeometer, Kipp & Zonen, CG4, SN 050768, WRMC No. 74003; Pyrheliometer, Eppley, NIP, SN 34093E6, WRMC No. 74005; Short-wave downward (GLOBAL) radiation; Short-wave downward (GLOBAL) radiation, maximum; Short-wave downward (GLOBAL) radiation, minimum; Short-wave downward (GLOBAL) radiation, standard deviation
    Type: Dataset
    Format: text/tab-separated-values, 486840 data points
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  • 4
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    Basic measurements of radiation at Concordia Station (2006-03) (2009)
    PANGAEA
    In:  Institute of Atmospheric Sciences and Climate of the Italian National Research Council, Bologna
    Details
    Publication Date: 2024-01-25
    Keywords: Antarctica; Baseline Surface Radiation Network; BSRN; Concordia Station, Dome C; DATE/TIME; Diffuse radiation; Diffuse radiation, maximum; Diffuse radiation, minimum; Diffuse radiation, standard deviation; Direct radiation; Direct radiation, maximum; Direct radiation, minimum; Direct radiation, standard deviation; DOM; HEIGHT above ground; Long-wave downward radiation; Long-wave downward radiation, maximum; Long-wave downward radiation, minimum; Long-wave downward radiation, standard deviation; Monitoring station; MONS; Pyranometer, Kipp & Zonen, CM22, SN 050108, WRMC No. 74002; Pyranometer, Kipp & Zonen, CM22, SN 050110, WRMC No. 74001; Pyrgeometer, Kipp & Zonen, CG4, SN 050768, WRMC No. 74003; Pyrheliometer, Eppley, NIP, SN 34093E6, WRMC No. 74005; Short-wave downward (GLOBAL) radiation; Short-wave downward (GLOBAL) radiation, maximum; Short-wave downward (GLOBAL) radiation, minimum; Short-wave downward (GLOBAL) radiation, standard deviation
    Type: Dataset
    Format: text/tab-separated-values, 698628 data points
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  • 5
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    Basic measurements of radiation at Concordia Station (2006-02) (2009)
    PANGAEA
    In:  Institute of Atmospheric Sciences and Climate of the Italian National Research Council, Bologna
    Details
    Publication Date: 2024-01-25
    Keywords: Antarctica; Baseline Surface Radiation Network; BSRN; Concordia Station, Dome C; DATE/TIME; Diffuse radiation; Diffuse radiation, maximum; Diffuse radiation, minimum; Diffuse radiation, standard deviation; Direct radiation; Direct radiation, maximum; Direct radiation, minimum; Direct radiation, standard deviation; DOM; HEIGHT above ground; Long-wave downward radiation; Long-wave downward radiation, maximum; Long-wave downward radiation, minimum; Long-wave downward radiation, standard deviation; Monitoring station; MONS; Pyranometer, Kipp & Zonen, CM22, SN 050108, WRMC No. 74002; Pyranometer, Kipp & Zonen, CM22, SN 050110, WRMC No. 74001; Pyrgeometer, Kipp & Zonen, CG4, SN 050768, WRMC No. 74003; Pyrheliometer, Eppley, NIP, SN 34093E6, WRMC No. 74005; Short-wave downward (GLOBAL) radiation; Short-wave downward (GLOBAL) radiation, maximum; Short-wave downward (GLOBAL) radiation, minimum; Short-wave downward (GLOBAL) radiation, standard deviation
    Type: Dataset
    Format: text/tab-separated-values, 641016 data points
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  • 6
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    Basic measurements of radiation at Concordia Station (2006-05) (2009)
    PANGAEA
    In:  Institute of Atmospheric Sciences and Climate of the Italian National Research Council, Bologna
    Details
    Publication Date: 2024-01-25
    Keywords: Antarctica; Baseline Surface Radiation Network; BSRN; Concordia Station, Dome C; DATE/TIME; Diffuse radiation; Diffuse radiation, maximum; Diffuse radiation, minimum; Diffuse radiation, standard deviation; Direct radiation; Direct radiation, maximum; Direct radiation, minimum; Direct radiation, standard deviation; DOM; HEIGHT above ground; Long-wave downward radiation; Long-wave downward radiation, maximum; Long-wave downward radiation, minimum; Long-wave downward radiation, standard deviation; Monitoring station; MONS; Pyranometer, Kipp & Zonen, CM22, SN 050108, WRMC No. 74002; Pyranometer, Kipp & Zonen, CM22, SN 050110, WRMC No. 74001; Pyrgeometer, Kipp & Zonen, CG4, SN 050768, WRMC No. 74003; Pyrheliometer, Eppley, NIP, SN 34093E6, WRMC No. 74005; Short-wave downward (GLOBAL) radiation; Short-wave downward (GLOBAL) radiation, maximum; Short-wave downward (GLOBAL) radiation, minimum; Short-wave downward (GLOBAL) radiation, standard deviation
    Type: Dataset
    Format: text/tab-separated-values, 702780 data points
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  • 7
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    Basic measurements of radiation at Concordia Station (2006-04) (2009)
    PANGAEA
    In:  Institute of Atmospheric Sciences and Climate of the Italian National Research Council, Bologna
    Details
    Publication Date: 2024-01-25
    Keywords: Antarctica; Baseline Surface Radiation Network; BSRN; Concordia Station, Dome C; DATE/TIME; Diffuse radiation; Diffuse radiation, maximum; Diffuse radiation, minimum; Diffuse radiation, standard deviation; Direct radiation; Direct radiation, maximum; Direct radiation, minimum; Direct radiation, standard deviation; DOM; HEIGHT above ground; Long-wave downward radiation; Long-wave downward radiation, maximum; Long-wave downward radiation, minimum; Long-wave downward radiation, standard deviation; Monitoring station; MONS; Pyranometer, Kipp & Zonen, CM22, SN 050108, WRMC No. 74002; Pyranometer, Kipp & Zonen, CM22, SN 050110, WRMC No. 74001; Pyrgeometer, Kipp & Zonen, CG4, SN 050768, WRMC No. 74003; Pyrheliometer, Eppley, NIP, SN 34093E6, WRMC No. 74005; Short-wave downward (GLOBAL) radiation; Short-wave downward (GLOBAL) radiation, maximum; Short-wave downward (GLOBAL) radiation, minimum; Short-wave downward (GLOBAL) radiation, standard deviation
    Type: Dataset
    Format: text/tab-separated-values, 657116 data points
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  • 8
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    Basic measurements of radiation at Concordia Station (2006-06) (2009)
    PANGAEA
    In:  Institute of Atmospheric Sciences and Climate of the Italian National Research Council, Bologna
    Details
    Publication Date: 2024-01-25
    Keywords: Antarctica; Baseline Surface Radiation Network; BSRN; Concordia Station, Dome C; DATE/TIME; Diffuse radiation; Diffuse radiation, maximum; Diffuse radiation, minimum; Diffuse radiation, standard deviation; Direct radiation; Direct radiation, maximum; Direct radiation, minimum; Direct radiation, standard deviation; DOM; HEIGHT above ground; Long-wave downward radiation; Long-wave downward radiation, maximum; Long-wave downward radiation, minimum; Long-wave downward radiation, standard deviation; Monitoring station; MONS; Pyranometer, Kipp & Zonen, CM22, SN 050108, WRMC No. 74002; Pyranometer, Kipp & Zonen, CM22, SN 050110, WRMC No. 74001; Pyrgeometer, Kipp & Zonen, CG4, SN 050768, WRMC No. 74003; Pyrheliometer, Eppley, NIP, SN 34093E6, WRMC No. 74005; Short-wave downward (GLOBAL) radiation; Short-wave downward (GLOBAL) radiation, maximum; Short-wave downward (GLOBAL) radiation, minimum; Short-wave downward (GLOBAL) radiation, standard deviation
    Type: Dataset
    Format: text/tab-separated-values, 549700 data points
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  • 9
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    Basic measurements of radiation at Concordia Station (2006-07) (2009)
    PANGAEA
    In:  Institute of Atmospheric Sciences and Climate of the Italian National Research Council, Bologna
    Details
    Publication Date: 2024-01-25
    Keywords: Antarctica; Baseline Surface Radiation Network; BSRN; Concordia Station, Dome C; DATE/TIME; Diffuse radiation; Diffuse radiation, maximum; Diffuse radiation, minimum; Diffuse radiation, standard deviation; Direct radiation; Direct radiation, maximum; Direct radiation, minimum; Direct radiation, standard deviation; DOM; HEIGHT above ground; Long-wave downward radiation; Long-wave downward radiation, maximum; Long-wave downward radiation, minimum; Long-wave downward radiation, standard deviation; Monitoring station; MONS; Pyranometer, Kipp & Zonen, CM22, SN 050108, WRMC No. 74002; Pyranometer, Kipp & Zonen, CM22, SN 050110, WRMC No. 74001; Pyrgeometer, Kipp & Zonen, CG4, SN 050768, WRMC No. 74003; Pyrheliometer, Eppley, NIP, SN 34093E6, WRMC No. 74005; Short-wave downward (GLOBAL) radiation; Short-wave downward (GLOBAL) radiation, maximum; Short-wave downward (GLOBAL) radiation, minimum; Short-wave downward (GLOBAL) radiation, standard deviation
    Type: Dataset
    Format: text/tab-separated-values, 706108 data points
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  • 10
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    Basic measurements of radiation at Concordia Station (2006-08) (2009)
    PANGAEA
    In:  Institute of Atmospheric Sciences and Climate of the Italian National Research Council, Bologna
    Details
    Publication Date: 2024-01-25
    Keywords: Antarctica; Baseline Surface Radiation Network; BSRN; Concordia Station, Dome C; DATE/TIME; Diffuse radiation; Diffuse radiation, maximum; Diffuse radiation, minimum; Diffuse radiation, standard deviation; Direct radiation; Direct radiation, maximum; Direct radiation, minimum; Direct radiation, standard deviation; DOM; HEIGHT above ground; Long-wave downward radiation; Long-wave downward radiation, maximum; Long-wave downward radiation, minimum; Long-wave downward radiation, standard deviation; Monitoring station; MONS; Pyranometer, Kipp & Zonen, CM22, SN 050108, WRMC No. 74002; Pyranometer, Kipp & Zonen, CM22, SN 050110, WRMC No. 74001; Pyrgeometer, Kipp & Zonen, CG4, SN 050768, WRMC No. 74003; Pyrheliometer, Eppley, NIP, SN 34093E6, WRMC No. 74005; Short-wave downward (GLOBAL) radiation; Short-wave downward (GLOBAL) radiation, maximum; Short-wave downward (GLOBAL) radiation, minimum; Short-wave downward (GLOBAL) radiation, standard deviation
    Type: Dataset
    Format: text/tab-separated-values, 692508 data points
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