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  • 1
    Electronic Resource
    Electronic Resource
    A new method for determining water–cation short-range potentials for modeling water in aluminosilicate lattices (1990)
    College Park, Md. : American Institute of Physics (AIP)
    The Journal of Chemical Physics 93 (1990), S. 3573-3579 
    Details
    ISSN: 1089-7690
    Source: AIP Digital Archive
    Topics: Physics , Chemistry and Pharmacology
    Notes: The problem of deriving realistic interaction potentials for modeling hydrated sites within aluminosilicate structures has been considered. It is argued that since a variety of cationic sites is involved, the effect of the lattice must be taken into account explicitly, both in the derivation and in the use of H2O–cation potentials. A new method for doing this is described with examples for H2O–Si4+ and H2O–Al3+ in quartz and/or zeolite-A. A more detailed analysis for H2O–Ca2+ in zeolite-A and cement structures is presented.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.458789
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  • 2
    Electronic Resource
    Electronic Resource
    Developmental regulation of cell-type-enriched mRNAs in Dictyostelium discoideum (1990)
    Oxford, UK : Blackwell Publishing Ltd
    Molecular microbiology 4 (1990), S. 0 
    Details
    ISSN: 1365-2958
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology , Medicine
    Notes: We describe sixteen new families of cDNA clones representing mRNAs that are expressed preferentially in either prespore or prestalk cells during developmentm of Dictyostelium discoideum and two new mRNAs that are expressed in a non-cell-type-specific manner. None of the prespore-enriched mRNAs are detectable in Dictyostelium cells until 13–15h of development but then they increase dramatically and peak at 18–22h. Upon dissociation of developing aggregates, all these mRNAs rapidly decay to low levels. In marked contrast to data presented for prespore genes by other workers, cyclic AMP either has no effect on the mRNA levels in dissociated cells or is only weakly effective in restoring normal expression. A prestalk-enriched mRNA examined, 5G mRNA, is similarly expressed late in development but is also expressed in vegetative cells. The level of 5G mRNA is only moderately affected by cell disaggregation.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2958.1990.tb00630.x
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  • 3
    Electronic Resource
    Electronic Resource
    Two cyclic AMP-regulated genes from Dictyostelium discoideum encode homologous proteins (1990)
    Oxford, UK : Blackwell Publishing Ltd
    Molecular microbiology 4 (1990), S. 0 
    Details
    ISSN: 1365-2958
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology , Medicine
    Notes: Expression of the 7E and 2C genes late in Dictyostelium development ceases upon cell disaggregation but, in contrast to many other genes we have studied, expression is fully restored by exogenous cAMP (A. J. Richards et af., submitted). The 7E and 2C genes encode polypeptides of similar size (9220 and 10573 Daltons, respectively), each of which contains an unusually high proportion of serine plus glycine residues (41% and 59%, respectively). Each protein possesses a relatively serine-rich N-terminus and glycine-rich C-terminus and contains the conserved sequence S(X)SSS(X2)SS(X)SS(X2)SFGS. These data suggest that genes 7E and 2C may have arisen by duplication of a common ancestor. Computer analysis indicates that both gene products are probably intra-cellular structural proteins that form extended coil structures.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2958.1990.tb02022.x
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  • 4
    Electronic Resource
    Electronic Resource
    Developmental expression and characterization of the gene encoding spore coat protein SP60 in Dictyostelium discoideum (1990)
    Oxford, UK : Blackwell Publishing Ltd
    Molecular microbiology 4 (1990), S. 0 
    Details
    ISSN: 1365-2958
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology , Medicine
    Notes: The complete coding sequence, upstream sequence and developmental expression of Dictyostelium discoideum AX2 spore coat protein gene SP60 is reported. The gene contains two exons, 154 bp and 1121 bp long, separated by a 119bp intron, and encodes a protein of 46925 molecular weight plus a 23-amino-acid hydrophobic leader sequence. The N-terminus of the mature protein consists of four copies of a perfect hexapeptide repeat (GDWNNN). The central region is rich in cysteine residues, including four highly conserved cysteine-rich repeats with homology to ‘EGF-like’ repeats. The C-terminus is aspartate-rich and composed of multiple imperfect copies of a D(G/D)DYD repeat followed by several repeats of the tetrapeptide DNDW and derived sequences. A TATA box promoter motif juxtaposed to an oligo(dA) stretch lies 52 bp upstream of the main transcriptional start site of the gene. Six AC-rich boxes occur in the region -327 to -556, all of which contain the consensus sequence CACAC. Two GC-rich boxes and a C-rich element (TTACCCCA) are also present upstream. Another open reading frame is positioned a short distance downstream of the SP60 gene in the opposite transcriptional orientation. Expression of the SP60 gene ceases upon disaggregation to single cells and cannot be restored by high levels of extracellular cAMP either alone or in combination with conditioned medium factors.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2958.1990.tb00668.x
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  • 5
    Electronic Resource
    Electronic Resource
    Cell-type-specific genes expressed late in Dictyostelium development show markedly different responses to 3′ 5′ cyclic AMP (1990)
    Oxford, UK : Blackwell Publishing Ltd
    Molecular microbiology 4 (1990), S. 0 
    Details
    ISSN: 1365-2958
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology , Medicine
    Notes: The maintenance of late gene expression by 3′ 5′ cyclic AMP was re-examined using several newly isolated cell-type-specific genes. Expression of all the prespore-enriched genes ceased immediately upon disaggregation of developing cells and pre-existing mRNA was rapidly degraded. For most genes, cAMP had little or no effect either alone or in combination with conditioned medium factors. The expression of the non-cell-type-specific genes 7E and 2C also ceased upon cell disaggregation but cAMP triggered a full re-induction of expression although the timing of the response differed markedly between these two genes. In contrast to earlier interpretations, these data argue that for none of these late prespore genes is cAMP alone sufficient for the maintenance of expression. The responses of the two prestalk mRNAs examined were gene-specific. Prestalk 5D mRNA decayed slowly upon disaggregation and was partially stabilized by cAMP whereas prestalk 5G mRNA increased upon disaggregation and was inhibited by cAMP.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2958.1990.tb00707.x
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  • 6
    Electronic Resource
    Electronic Resource
    COL3A1 mutations cause variable clinical phenotypes including acrogeria and vascular rupture (1996)
    Oxford, UK : Blackwell Publishing Ltd
    British journal of dermatology 135 (1996), S. 0 
    Details
    ISSN: 1365-2133
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Summary We have recently analysed by hislological, protein and molecular DNA techniques 23 mutations of the collagen III gene (COL3AI). most of which cause premature arterial fragility, thin skin and variants of vascular Ehlers-Danlos syndrome. There were 14 glycinesubstitutions between residues 637 and 1021. eight exon skips between exons 7 and 45 and one small inframe deletion. The glycine substitutions produce a gradient of increasingly abnormal clinical phenotypes from exons 36 to 49 while the clinical severity of exon skips is much more variable. Each mutation is private for the affected family or individual concerned having the potential for early prenatal diagnosis and prevention.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2133.1996.tb01143.x
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  • 7
    Electronic Resource
    Electronic Resource
    Reproduction in flowering plants (1979)
    [s.l.] : Nature Publishing Group
    Nature 278 (1979), S. 306-306 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] INTRODUCING the International Sym-posium on the Reproduction of Flower-ing Plants, held recently in New Zealand*, E. J. Godley (DSIR, Christ-church) discussed the special character-istics of the New Zealand flora. One question posed was whether the pro-portion of unisexual flowers found in New ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/278306a0
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  • 8
    Electronic Resource
    Electronic Resource
    2-Benzamido-3-(p-chlorophenyl)propenoic Acid (Antrex) (1995)
    Oxford [u.a.] : International Union of Crystallography (IUCr)
    Acta crystallographica 51 (1995), S. 2338-2340 
    Details
    ISSN: 1600-5759
    Source: Crystallography Journals Online : IUCR Backfile Archive 1948-2001
    Topics: Chemistry and Pharmacology , Geosciences , Physics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1107/S010827019500672X
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  • 9
    Electronic Resource
    Electronic Resource
    Sexuality and Apomixis in Taraxacum (1967)
    [s.l.] : Nature Publishing Group
    Nature 214 (1967), S. 114-114 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Fiirnkranz also found that diploid sexuals have regular pollen and polyploid apomicts irregular pollen, presumably because of multivalent formation and partial restitution during male meiosis in the apomicts. He found that most populations in the sections Vulgaria (= T. officinale Weber) and ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/214114a0
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  • 10
    Electronic Resource
    Electronic Resource
    Plant ecology: The sex life of primroses (1984)
    [s.l.] : Nature Publishing Group
    Nature 310 (1984), S. 12-13 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] A BLAZING controversy is best fuelled by a lack of good data. Crosby's discovery of a self-pollinating self-fertilizing primrose was accompanied by the contentious claim that the variant would spread rapidly through southern England because of the advantage that selfing seems to offer (based ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/310012a0
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