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  • 1
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Pediatric allergy and immunology 6 (1995), S. 0 
    ISSN: 1399-3038
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Lectins recognize carbohydrate moities of glycoproteins and glycolipids, and can elicit several biological effects, including cell agglutination, cell activation and mitogenesis. According to the gluten-lectin theory, celiac lesions represent a response to a toxic lectin, putatively wheat germ agglutinin (WGA). In this study we compared the serum antibody levels IgA, IgG and IgM to WGA and to gliadin in children under investigation for celiac disease (CD), as compared to reference children. We found that the levels of IgA and IgG to WGA as well as gliadin were significantly higher in celiac children on a gluten-containing diet, compared to children on gluten-free diet and reference children. These findings lend support to the concept that WGA is a biologically significant component of gluten. Since WGA can mimic the effects of epidermal growth factor (EGF) at the cellular level, we hypothezise that the crypt hyperplasia seen in celiac children could be due to a mitogenic response induced by WGA.
    Type of Medium: Electronic Resource
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  • 2
    Publication Date: 2021-09-03
    Description: The purpose of the guidelines is to review existing knowledge and provide guidance for designing an Arctic monitoring program that will track litter and MP. The topics of litter, plastic pollution, and MP are addressed in many fora, including several of the Arctic Council working groups: Arctic Monitoring and Assessment Programme (AMAP; https://www.amap.no/documents/doc/amap-assessment-2016-chemicals-of-emerging-arctic-concern/1624), Protection of the Marine Environment (PAME, 2019), and Conservation of the Arctic Flora and Fauna (CAFF). The development of an Arctic monitoring program and its technical approaches will be based on the work that already exists in other programs such as those of OSPAR, the Helsinki Commission (HELCOM), the International Council for the Exploration of the Sea (ICES), the Organisation for Economic Co-operation and Development (OECD), and the United Nations Environment Programme (UNEP). Plastic pollution is typically categorized into items and particles of macro-, micro-, and nano-sizes. These guidelines address macrosized litter as well as MP (〈 5 mm), essentially including smaller size ranges (〉1 µm). However, determination of nanoplastic (〈 1 µm) particles is still hampered by technical challenges, as addressed in Section 4.3 Analytical methods, and thus not currently considered in the current recommendations. Although most studies have addressed marine litter and MP, these guidelines also comprise the Arctic’s terrestrial and freshwater environments. Thus, the objectives of the guidelines are to: 1) support litter and MP baseline mapping in the Arctic across a wide range of environmental compartments to allow spatial and temporal comparisons in the coming years; 2) initiate monitoring to generate data to assess temporal and spatial trends; 3) recommend that Arctic countries develop and implement monitoring nationally via community-based programs and other mechanisms, in the context of a pan-Arctic program; 4) provide data that can be used with the Marine Litter Regional Action Plan (ML-RAP) to assess the effectiveness of mitigation strategies; 5) act as a catalyst for future work in the Arctic related to biological effects of plastics, including determining environmentally relevant concentrations and informing cumulative effects assessments; 6) identify areas in which research and development are needed from an Arctic perspective; and 7) provide recommendations for monitoring programs whose data will feed into future global assessments to track litter and MP in the environment. To achieve these objectives, the guidelines present indicators (with limitations) of litter and MP pollution to be applied throughout the Arctic, and thus, form the basis for circumpolar comparability of approaches and data. In addition, the guidelines present technical details for sampling, sample treatment, and plastic determination, with harmonized and potentially standardized approaches. Furthermore, recommendations are given on sampling locations and sampling frequency based on best available science to provide a sound basis for spatial and temporal trend monitoring. As new data are gathered, and appropriate power analyses can be undertaken, a review of the sampling sizes, locations, and frequencies should be initiated. Plastic pollution is a local problem in Arctic communities, and thus, guidelines and references need to include community-based monitoring projects to empower communities to establish plastics monitoring with comparable results across the Arctic. Community-based monitoring is an integrated part of the objectives of this report. The monitoring program design and guidelines for its implementation are the necessary first steps for monitoring and assessment of litter and MP in the Arctic. The work under the AMAP LMEG is taking a phased approach under this new expert group. The first phase (which included the development of these Monitoring Guidelines) focuses on a monitoring framework and set of techniques for physical plastics. Later phases of the work will extend to assessments of levels, trends, and effects of litter and MP in the Arctic environment. The guidelines strictly cover environmental monitoring of litter and MP. This does not include drinking water or indoor air quality tests. Additionally, although there is an emphasis on examining litter and MP in biota that are consumed by humans, and thus of interest to human-health questions, the guidelines do not consider MP ingestion by humans.
    Repository Name: EPIC Alfred Wegener Institut
    Type: Miscellaneous , notRev
    Format: application/pdf
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  • 3
    Publication Date: 2022-07-07
    Description: The atmosphere and cryosphere have recently garnered considerable attention due to their role in transporting microplastics to and within the Arctic, and between freshwater, marine, and terrestrial environments. While investigating either in isolation provides valuable insight on the fate of microplastics in the Arctic, monitoring both provides a more holistic view. Nonetheless, despite the recent scientific interest, fundamental knowledge on microplastic abundance, and consistent monitoring efforts, are lacking for these compartments. Here, we build upon the work of the Arctic Monitoring and Assessment Programme’s Monitoring Guidelines for Litter and Microplastic to provide a roadmap for multi-compartment monitoring of the atmosphere and cryosphere to support our understanding of the sources, pathways, and sinks of plastic pollution across the Arctic. Overall, we recommend the use of existing standard techniques for ice and atmospheric sampling and to build upon existing monitoring efforts in the Arctic to obtain a more comprehensive pan-Arctic view of microplastic pollution in these two compartments.
    Repository Name: EPIC Alfred Wegener Institut
    Type: Article , NonPeerReviewed
    Format: application/pdf
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  • 4
    Publication Date: 2022-10-04
    Repository Name: EPIC Alfred Wegener Institut
    Type: Conference , notRev
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  • 5
    Publication Date: 2023-06-21
    Description: *
    Repository Name: EPIC Alfred Wegener Institut
    Type: Conference , notRev
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  • 6
    Publication Date: 2023-06-21
    Description: Litter and microplastic assessments are being carried out worldwide. Arctic ecosystems are no exception and plastic pollution is high on the Arctic Council’s agenda. Water and sediment have been identified as two of the priority compartments for monitoring plastics under the Arctic Monitoring and Assessment Programme (AMAP). Recommendations for monitoring both compartments are presented in this publication. Alone, such samples can provide information on presence, fate, and potential impacts to ecosystems. Together, the quantification of microplastics in sediment and water from the same region produce a three-dimensional picture of plastics, not only a snapshot of floating or buoyant plastics in the surface water or water column but also a picture of the plastics reaching the shoreline or benthic sediments, in lakes, rivers, and the ocean. Assessment methodologies must be adapted to the ecosystems of interest to generate reliable data. In its current form, published data on plastic pollution in the Arctic is sporadic and collected using a wide spectrum of methods which limits the extent to which data can be compared. A harmonised and coordinated effort is needed to gather data on plastic pollution for the Pan-Arctic. Such information will aid in identifying priority regions and focusing mitigation efforts.
    Repository Name: EPIC Alfred Wegener Institut
    Type: Article , isiRev
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  • 7
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Geophysical prospecting 30 (1982), S. 0 
    ISSN: 1365-2478
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Geosciences , Physics
    Notes: A suite of electrical, radiation, and mechanical borehole probes were run in a 76-mm-diameter borehole drilled to a slant depth of 380 m in leptite and granite. The hole is located in Precambrian bedrock in central Sweden where a site is dedicated to in-situ experiments pertaining to the disposal of radioactive wastes. The challenge to borehole logging methods for such site investigations is to resolve geological features and fluid flow parameters in geological sites which are initially chosen for their homogeneity, low porosity, and minimal fracturing. The Stripa borehole is characterized by high electrical resistivity values in the 20–100 kΩm range, by acoustic velocities around 5800 m s-1 (which is close to laboratory values on intact specimens), and by total porosity of around one volume percent. In this context, probe resolution was adequate to produce interpretable information on almost all of the logs.Two principal rock types were encountered in the hole: granite, of quartz monzonitic composition, and leptite. The granite and leptite intercepts are subdivided into units characterized by mafic mineral content, sulfide mineral content, and electrical and radiation properties. Iron-rich zones in the leptite are highly anomalous on the gamma-gamma and neutron logs; thin mafic zones in the granite can also be distinguished. Occurrences of a few percent pyrite are detected by the electrical, gamma-gamma, and neutron logs. Although overall porosity is quite low throughout the hole, analysis of the resistivity and neutron logs indicates the porosity increases by a few volume percent at fracture zones. The differential resistance and caliper probes detect borehole diameter roughness of less than 1 mm, helping to confirm acoustic waveform anomalies which are indicative of fracture zones. Compres-sional wave transit time and shear-wave interference patterns usually occur coincident with open fractures observed in core, the correlation being especially good at major fracture zones.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 76 (1994), S. 7405-7409 
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: The Schottky barrier formation between Bi and polycrystalline, ceramic ZnO has been studied with photoelectron spectroscopy (PES) under ultrahigh-vacuum conditions. This system is a simple model of a varistor compound. Evaporation of Bi on highly n-doped (Al) sintered ZnO surfaces, fractured in situ and held at room temperature, results in considerable upward band bending. After evaporation of 10 A(ring) of Bi (approximately 3 monolayer coverage), the Bi-induced band bending amounts to 0.43 eV, as evident from the energy shift of the Bi 5d emission in PES. From valence-band and band-gap studies using ultraviolet PES, the states responsible for the observed band bending could be identified: Bi induces states in the ZnO band gap at 0.9 eV above the valence-band maximum. The filling of this high density of band-gap states results in a pinning of the surface Fermi level which makes the band bending proportional to the Bi coverage, with a rapid increase during the formation of the first monolayer and markedly slower thereafter. These results show the importance of Bi in the formation of the varistor Schottky barriers. © 1994 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Allergy 42 (1987), S. 0 
    ISSN: 1398-9995
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: To study the possibility of intrauterine sensitization, 212 women were enrolled on a voluntary basis into a prospective, randomized study, comparing the effects of an elimination diet and normal food during late pregnancy. The diet group took no cow milk and no egg from week 28 to delivery, and extra calcium and casein hydrolysate (Nutramigen ®) supplement was given to fill the nutritional needs of mother and child. The control group took normal food, including approximately 1/2 liter of milk/day and 3–5 eggs/week. All families had a history of allergy in mother, father, or sibling. Maternal weight gain during pregnancy was significantly lower in the diet group. Birth weights showed no significant difference between the two main groups, but smokers in the elimination diet group had significantly smaller babies. IgE antibodies to cow milk and egg were significantly higher in atopic than in non-atopic women before the trial. The diet caused a significant fall in IgG-antibodies to cow milk and egg in both atopic and non-atopic subjects. Cord blood IgE determination revealed no significant difference between the groups. No IgE antibodies to cow milk or egg were detected in any of the cord sera. The participating babies are being followed up until 18 months of age.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Scandinavian journal of immunology 9 (1979), S. 0 
    ISSN: 1365-3083
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: An opto-electronic device has been used for a quantitative assessment of the motility of individual polymorphonuclear leucocytes (PMNL) adhering to a glass cover slip. One of the oculars in a phase contrast microscope is provided with a mini-array of 32 × 32 light-sensitive elements. These are connected lo an electronic unit, capable of recording the number of light-intensity changes on each element and of visualizing the path of a cell on an oscilloscope screen, as a pattern of dots. The results clearly show that individual PMNL respond differently to environmental conditions; for instance, (ij raising the temperature increased the motility of cells to a maximum at around 39°C and lowering the temperature from 42°C restored their peak motility. (ii) protein was required at attachment depending on the temperature at attachment, (iii) endo-toxin-activated normal human serum affected more drastically cells with a low initial motility and cytochalasin B more adversely influenced cells with a high initial motility. (iv) phagocytosis of yeast cells reduced the percentage of motile ceils, which was more pronounced if the PMNL were washed before the mobility measurement. The average motility of the PMNL was also diminished, although individual PMNL retained normal activity after ingestion of one or more yeast cells.
    Type of Medium: Electronic Resource
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