Keywords:
Peptides -- Synthesis.
;
Peptides.
;
Electronic books.
Type of Medium:
Online Resource
Pages:
1 online resource (516 pages)
Edition:
1st ed.
ISBN:
9781483218007
URL:
https://ebookcentral.proquest.com/lib/geomar/detail.action?docID=1874948
Language:
English
Note:
Front Cover -- Conformation in Biology and Drug Design -- Copyright Page -- Table of Contents -- Contributors -- Preface -- Nomenclature and Abbreviations -- Chapter 1. A Perspective on the Application of Physical Methods to Peptide Conformational-Biological Activity Studies -- I. Introduction -- II. Some Biological Considerations -- III. Historical Development of Peptide Conformational Studies in Solution -- IV. Theoretical Methods for Examining Peptide Conformations -- V. Application of Conformational and Dynamic Studies of Peptides to Their Biological Activities -- Acknowledgment -- References -- Chapter 2. Circular Dichroism of Peptides -- I. Introduction -- II. General Aspects of Peptide CD -- III. Specific Systems -- Acknowledgments -- References -- Chapter 3. Application of Fluorescence Techniques in Studies of Peptide Conformations and Interactions -- I. Introductory Remarks -- II. Fluorophores in Peptides -- III. Fluorescence Quantum Yield and Lifetime Measurements -- IV. Fluorescence Polarization Studies -- V. Measurement of Intramolecular Distances by Singlet-Singlet Resonance Energy Transfer Experiments -- VI. Fluorescence Studies of Peptide Interactions with Macromolecular Systems -- VII. Concluding Remarks -- Acknowledgment -- References -- Chapter 4. Theoretical Methods in the Analysis of Peptide Conformation -- I. Introduction -- II. Definitions and Conventions -- III. Methodology -- IV. Results -- References -- Chapter 5. Theoretical Simulation of Conformation, Energetics, and Dynamics of Peptides -- I. Introduction -- II. Techniques and Methodology -- III. Applications -- IV. Summary and Future Directions -- Acknowledgments -- References -- Chapter 6. Paramagnetic Metal Ions as Nuclear Magnetic Resonance Probes of Peptide Conformation in Solution -- I. Introduction.
,
II. Paramagnetic Metal Ion-Induced Shifts and Relaxation Enhancements -- III. Conclusions -- References -- Chapter 7. Nuclear Magnetic Resonance Studies of Peptide-Macromolecule Interactions -- I. Introduction -- II. Nuclear Magnetic Resonance Techniques -- III. Peptide-Protein Interaction -- IV. Peptide-Lipid Interaction -- V. Peptide-Nucleic Acid Interactions -- VI. Conclusions and Prospects -- References -- Chapter 8. Solid-State Nuclear Magnetic Resonance of Peptides -- I. Introduction -- II. Methods -- III. Applications -- IV. Prospects -- Acknowledgments -- References -- Chapter 9. Modern Nuclear Magnetic Resonance Spectroscopy of Peptides -- I. Introduction -- II. Conformational Homogeneity -- III. General Strategy for Nuclear Magnetic Resonance Investigation of Peptides -- IV. Assignment of Proton Nuclear Magnetic Resonance Signals -- V. Heteronuclear Techniques -- VI. Sequence Analysis -- VII. Quantitative Evaluation of Nuclear Magnetic Resonance Spectra -- VIII. Conclusions -- Acknowledgments -- References -- Index.
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