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  • 1
    ISSN: 1432-2056
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary Phytoplankton biomass and distribution of major phytoplankton groups were investigated in relation to sea ice conditions, hydrography and nutrients along three north-south transects in the north western Weddell Sea in early spring 1988 during the EPOS Study (European Polarstern Study), Leg 1. Three different zones along the transects could be distinguished: 1) the Open Water Zone (OWZ) from 58° to 60°S with high chlorophyll a concentrations up to 3.5 μg l−1; 2) the Marginal Ice Zone (MIZ) from 60° to about 62.5° with chlorophyll a concentrations between 0.1 and 0.3 μg l−1, and 3) the closed pack-ice zone (CPI) from 62.5° to 63.2°S with chlorophyll a concentrations below 0.1 μgl−1. Nutrient concentrations increased towards the south showing winter values under the closed pack-ice. Centric diatoms such as Thalassiosira gravida and Chaetoceros neglectum forming large colonies dominated the phytoplankton assemblage in terms of biomass in open water together with large, long chain forming, pennate diatoms, whereas small pennate diatoms such as Nitzschia spp., and nanoflagellates prevailed in ice covered areas. Fairly low concentrations of phytoplankton cells were encountered at the southernmost stations and many empty diatom frustules were found in the samples. The enhanced phytoplankton biomass in the Weddell-Scotia-Confluence area is achieved through sea ice melting in the frontal zone of two different water masses, the Weddell and the Scotia Sea surface waters.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1432-198X
    Keywords: Key words Vesicoureteric reflux ; Cyclic voiding cystourethrography ; Occult vesicoureteric reflux ; Upgrading ; Downgrading
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract  Cyclic voiding cystourethrography (CVC) enhances the detection of vesicoureteric reflux (VUR). We investigated whether more-severe VUR may be overlooked, and whether older children are at risk of having their VUR missed with the conventional single-cycle study. Three hundred and seventy patients, 168 boys and 202 girls aged 1 month to 16 years, consecutively admitted over 1 year for suspicion of VUR, underwent two complete cycles of filling and voiding CVC. One hundred and four subjects, 33 boys and 71 girls, were older than 3 years (mean age 5.7 years, range 3.2–16 years).Sixty-six refluxing ureters from 51 patients were identified in the first cycle and 61 refluxing ureters from 45 patients were identified only with the second cycle. Four instances of grade IV VUR in 4 patients and three of grade V VUR in 3 patients were overlooked completely in the first cycle. Seven episodes of VUR ≤ grade III from 5 patients diagnosed in the first cycle were upgraded to ≥ grade IV at the second cycle. The presence of VUR was identified only in the second cycle in 35 of 74 subjects aged ≤ 3 years and in 10 of 22 aged 〉3 years (not significant). Of the 10 children aged 〉3 years, 2, who had diagnosis only at the second cycle, had ≥ grade IV VUR. More-severe VUR may be overlooked or down-graded in a single-cycle study. Two-cycle CVC is also useful in children older than 3 years.
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  • 3
    ISSN: 1432-198X
    Keywords: Key words Hypercalciuria ; Calculi ; Microcalculi ; Hematuria ; Abdominal pain ; Dysuria
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract  Idiopathic hypercalciuria (IHC) has been reported mainly in children with hematuria in the 1980s and early 1990s, when renal sonography was just becoming routine. The presence of microcalculi, i.e., of hyperechogenic spots 〈3 mm in diameter in renal calyces, was not taken into account in those studies. We attempted to outline clinical presentation and natural course of IHC not only in children with hematuria, but also in those with dysuria and/or recurrent abdominal/flank pain and a family history of nephrolithiasis, taking into account the finding of microcalculi. We analyzed retrospectively the data at diagnosis from 74 consecutive children aged 2.4–18 years (mean 8.6) with IHC (calciuria 4.1–15.1 mg kg–1 24 h–1, mean 6.1) and the outcome of 30 of them who were followed ≥1 years (mean 3.2) with no specific therapy. At diagnosis, 38 patients (51%) had no hematuria, 42 (57%) had microcalculi and four (5%) had calculi. Of the patients with normal urinalysis, 71% had microcalculi or stones. The subjects with microcalculi and those with stones were significantly older than those without microcalculi and stones (P=0.004 and 0.007). A normal urinalysis at our evaluation and a history of abdominal/flank pain were significantly more frequent in patients with microcalculi than in those without (P=0.02 and 0.0001, respectively). During the follow-up, four of 30 patients formed stones 1–3 years after first diagnosis of IHC. More than half of children with IHC have microcalculi. The risk of formation of microcalculi or stones increases with age. The lack of hematuria does not exclude the presence of microcalculi or calculi. Hypercalciuria has to be suspected in children with dysuria and/or recurrent abdominal/ flank pain and a family history of nephrolithiasis, even when they have no hematuria.
    Type of Medium: Electronic Resource
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  • 4
    Publication Date: 2014-11-14
    Description: Protumorigenic effects of mir-145 loss in malignant pleural mesothelioma Oncogene 33, 5319 (13 November 2014). doi:10.1038/onc.2013.476 Authors: M Cioce, F Ganci, V Canu, A Sacconi, F Mori, C Canino, E Korita, B Casini, G Alessandrini, A Cambria, M A Carosi, R Blandino, V Panebianco, F Facciolo, P Visca, S Volinia, P Muti, S Strano, C M Croce, H I Pass & G Blandino
    Keywords: mesotheliomaOCT4mir-145mesothelial cystschemoresistancesenescence
    Print ISSN: 0950-9232
    Topics: Medicine
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  • 5
    Publication Date: 2019-07-16
    Repository Name: EPIC Alfred Wegener Institut
    Type: Article , isiRev
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