ISSN:
1434-4475
Keywords:
Keywords. Asymmetric reduction; Chiral boranes; Steroid-20-one.
Source:
Springer Online Journal Archives 1860-2000
Topics:
Chemistry and Pharmacology
Notes:
Summary. The synthesis of a new chiral boroxazolidine was achieved which was used to control the stereochemistry of the borane reduction of the 20-keto group of steroids. The otherwise hardly accessible 20α-(20S)-alcohol can thus be prepared in a yield of 91%.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/s007060070037
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